Nguyên tắc phân loại các tác động tiềm năng đến sức khỏe con người từ việc tiếp xúc với nanomaterial: các yếu tố của một chiến lược sàng lọc
Tóm tắt
Sự phát triển nhanh chóng của nhiều loại vật liệu nano công nghệ (được định nghĩa là các vật liệu được thiết kế và sản xuất có các đặc điểm cấu trúc với ít nhất một kích thước nhỏ hơn 100 nanomet) đã đặt ra một tình huống khó khăn cho các nhà quản lý trong việc xác định mối nguy. Viện Nghiên cứu Khoa học Đời sống Quốc tế / Viện Khoa học Rủi ro đã tập hợp một nhóm chuyên gia để phát triển chiến lược sàng lọc cho việc xác định mối nguy của các vật liệu nano công nghệ. Báo cáo của nhóm làm việc trình bày các
Có khả năng cao rằng hoạt tính sinh học của các hạt nano sẽ phụ thuộc vào các tham số lý hóa mà thường không được xem xét trong các nghiên cứu sàng lọc độc tính. Các tính chất lý hóa có thể quan trọng trong việc hiểu các tác động độc hại của các vật liệu thử nghiệm bao gồm kích thước và phân bố kích thước hạt, trạng thái agglomeration, hình dạng, cấu trúc tinh thể, thành phần hóa học, diện tích bề mặt, hóa học bề mặt, điện tích bề mặt, và độ xốp.
Các kỹ thuật
Từ khóa
#vật liệu nano #độc tính #sức khỏe con người #chiến lược sàng lọc #đánh giá rủi roTài liệu tham khảo
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