Principals of neovascularization for tissue engineering

Molecular Aspects of Medicine - Tập 23 Số 6 - Trang 463-483 - 2002
Masashi Nomi1, Anthony Atala1, Paolo De Coppi1, Shay Söker1
1Department of Urology, Laboratory for Cellular Therapeutics and Tissue Engineering, Children's Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA

Tóm tắt

Từ khóa


Tài liệu tham khảo

Abraham, 1986, Nucleotide sequence of a bovine clone encoding the angiogenic protein, basic fibroblast growth factor, Science, 233, 545, 10.1126/science.2425435

Adamis, 1994, Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy, Am. J. Ophthalmol., 118, 445, 10.1016/S0002-9394(14)75794-0

Ajioka, 2001, Establishment of heterotropic liver tissue mass with direct link to the host liver following implantation of hepatocytes transfected with vascular endothelial growth factor gene in mice, Tissue Eng., 7, 335, 10.1089/10763270152044198

Asahara, 1996, Accelerated restitution of endothelial integrity and endothelium-dependent function after phVEGF165 gene transfer, Circulation, 94, 3291, 10.1161/01.CIR.94.12.3291

Asahara, 1999, Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization, Circ. Res., 85, 221, 10.1161/01.RES.85.3.221

Asahara, 1997, Isolation of putative progenitor endothelial cells for angiogenesis, Science, 275, 964, 10.1126/science.275.5302.964

Asahara, 1999, VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells, EMBO J., 18, 3964, 10.1093/emboj/18.14.3964

Atala, 2000, Tissue engineering, World J. Urol., 18, 1, 10.1007/s003450050001

Baffour, 1992, Enhanced angiogenesis and growth of collaterals by in vivo administration of recombinant basic fibroblast growth factor in a rabbit model of acute lower limb ischemia: dose–response effect of basic fibroblast growth factor, J. Vasc. Surg., 19, 181, 10.1016/0741-5214(92)90106-I

Basilico, 1992, The FGF family of growth factors and oncogenes, Adv. Cancer Res., 59, 115, 10.1016/S0065-230X(08)60305-X

Battegay, 1995, Angiogenesis: mechanistic insights, neovascular diseases, and therapeutic prospects, J. Mol. Med., 73, 333, 10.1007/BF00192885

Bauters, 1995, Site-specific therapeutic angiogenesis after systemic administration of vascular endothelial growth factor, J. Vasc. Surg., 21, 314, 10.1016/S0741-5214(95)70272-5

Bikfalvi, 1997, Biological roles of fibroblast growth factor-2, Endocr. Rev., 18, 26, 10.1210/er.18.1.26

Breier, 1992, Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation, Development, 114, 521, 10.1242/dev.114.2.521

Burgess, 1986, Structural evidence that endothelial cell growth factor beta is the precursor of both endothelial cell growth factor alpha and acidic fibroblast growth factor, Proc. Natl. Acad. Sci. USA, 83, 7216, 10.1073/pnas.83.19.7216

Bussolino, 1992, Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth, J. Cell Biol., 119, 629, 10.1083/jcb.119.3.629

Carmeliet, 2000, Developmental biology. One cell two fates, Nature, 408, 43, 10.1038/35040684

Carmeliet, 2001, Growing better blood vessels, Nat. Biotechnol., 19, 1019, 10.1038/nbt1101-1019

Carmeliet, 1996, Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele, Nature, 380, 435, 10.1038/380435a0

Carmeliet, 1999, Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188, Nat. Med., 5, 495, 10.1038/8379

Darland, 1999, Blood vessel maturation: vascular development comes of age, J. Clin. Invest., 103, 157, 10.1172/JCI6127

Davis, 1999, The angiopoietins: Yin and Yang in angiogenesis, Curr. Top Microbiol. Immunol., 237, 173

de Vries, 1992, The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor, Science, 255, 989, 10.1126/science.1312256

Drake, 1998, Morphogenesis of the first blood vessels, Ann. NY Acad. Sci., 857, 155, 10.1111/j.1749-6632.1998.tb10115.x

Dvorak, 1995, Vascular permeability factor/vascular endothelial growth factor: an important mediator of angiogenesis in malignancy and inflammation, Int. Arch. Allergy Immunol., 107, 233, 10.1159/000236988

Dvorak, 1991, Distribution of vascular permeability factor (vascular endothelial growth factor) in tumors: concentration in tumor blood vessels, J. Exp. Med., 174, 1275, 10.1084/jem.174.5.1275

Edelman, 1991, Controlled and modulated release of basic fibroblast growth factor, Biomaterials, 12, 619, 10.1016/0142-9612(91)90107-L

Eiselt, 1998, Development of technologies aiding large-tissue engineering, Biotechnol. Prog., 14, 134, 10.1021/bp970135h

Ferrara, 1999, Molecular and biological properties of vascular endothelial growth factor, J. Mol. Med., 77, 527, 10.1007/s001099900019

Ferrara, 2001, Role of vascular endothelial growth factor in regulation of physiological angiogenesis, Am. J. Physiol. Cell Physiol., 280, C1358, 10.1152/ajpcell.2001.280.6.C1358

Ferrara, 1996, Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene, Nature, 380, 439, 10.1038/380439a0

Finnerty, 1993, Molecular cloning of murine FLT and FLT4, Oncogene, 8, 2293

Flamme, 1997, Molecular mechanisms of vasculogenesis and embryonic angiogenesis, J. Cell Physiol., 173, 206, 10.1002/(SICI)1097-4652(199711)173:2<206::AID-JCP22>3.0.CO;2-C

Folkman, 1992, The role of angiogenesis in tumor growth, Semin. Cancer Biol., 3, 65

Folkman, 1997, Angiogenesis and angiogenesis inhibition: an overview, Exs, 79, 1

Folkman, 2001, Angiogenesis-dependent diseases, Semin. Oncol., 28, 536, 10.1016/S0093-7754(01)90021-1

Folkman, 1992, Angiogenesis and inflamation, 821

Folkman, 1996, Blood vessel formation: what is its molecular basis?, Cell, 87, 1153, 10.1016/S0092-8674(00)81810-3

Folkman, 1992, Angiogenesis, J. Biol. Chem., 267, 10931, 10.1016/S0021-9258(19)49853-0

Fong, 1995, Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium, Nature, 376, 66, 10.1038/376066a0

Fontaine, 1995, Human hepatocyte isolation and transplantation into an athymic rat, using prevascularized cell polymer constructs, J. Pediatr. Surg., 30, 50, 10.1016/0022-3468(95)90610-X

Frank, 1995, Regulation of vascular endothelial growth factor expression in cultured keratinocytes. Implications for normal and impaired wound healing, J. Biol. Chem., 270, 12607, 10.1074/jbc.270.21.12607

Furlong, 1991, Comparison of biological and immunochemical properties indicates that scatter factor and hepatocyte growth factor are indistinguishable, J. Cell Sci., 100, 173, 10.1242/jcs.100.1.173

Gherardi, 1991, Hepatocyte growth factor – scatter factor: mitogen, motogen, and met, Cancer Cells, 3, 227

Gilbert, 1993, Cell transplantation of genetically altered cells on biodegradable polymer scaffolds in syngeneic rats, Transplantation, 56, 423, 10.1097/00007890-199308000-00033

Grant, 1993, Scatter factor induces blood vessel formation in vivo, Proc. Natl. Acad. Sci. USA, 90, 1937, 10.1073/pnas.90.5.1937

Gratton, 2001, Akt down-regulation of p38 signaling provides a novel mechanism of vascular endothelial growth factor-mediated cytoprotection in endothelial cells, J. Biol. Chem., 276, 30359, 10.1074/jbc.M009698200

Grunstein, 2000, Isoforms of vascular endothelial growth factor act in a coordinate fashion to recruit and expand tumor vasculature, Mol. Cell Biol., 20, 7282, 10.1128/MCB.20.19.7282-7291.2000

Hanahan, 1997, Signaling vascular morphogenesis and maintenance, Science, 277, 48, 10.1126/science.277.5322.48

Hanahan, 1996, Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis, Cell, 86, 353, 10.1016/S0092-8674(00)80108-7

Henry, 1999, Therapeutic angiogenesis, BMJ, 318, 1536, 10.1136/bmj.318.7197.1536

Houck, 1992, Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms, J. Biol. Chem., 267, 26031, 10.1016/S0021-9258(18)35712-0

Isner, 1998, Vascular endothelial growth factor: gene therapy and therapeutic angiogenesis, Am. J. Cardiol., 82, 63S, 10.1016/S0002-9149(98)90439-8

Isner, 1998, Therapeutic angiogenesis, Front Biosci., 3, e49, 10.2741/A367

Isner, 1999, Therapeutic angiogenesis for heart failure, Nat. Med., 5, 491, 10.1038/8374

Isner, 1996, Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb, Lancet, 348, 370, 10.1016/S0140-6736(96)03361-2

Jiang, 1997, Hepatocyte growth factor/scatter factor, a cytokine playing multiple and converse roles, Histol. Histopathol., 12, 537

Joki, 2001, Continuous release of endostatin from microencapsulated engineered cells for tumor therapy, Nat. Biotechnol., 19, 35, 10.1038/83481

Kalka, 2000, Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularization, Proc. Natl. Acad. Sci. USA, 97, 3422, 10.1073/pnas.070046397

Kaushal, 2001, Functional small-diameter neovessels created using endothelial progenitor cells expanded ex vivo, Nat. Med., 7, 1035, 10.1038/nm0901-1035

Keck, 1989, Vascular permeability factor, an endothelial cell mitogen related to PDGF, Science, 246, 1309, 10.1126/science.2479987

Keyt, 1996, The carboxyl-terminal domain (111–165) of vascular endothelial growth factor is critical for its mitogenic potency, J. Biol. Chem., 271, 7788, 10.1074/jbc.271.13.7788

King, 1996, The cellular and molecular mechanisms of diabetic complications, Endocrinol. Metab Clin. North Am., 25, 255, 10.1016/S0889-8529(05)70324-8

Klagsbrun, 1991, A dual receptor system is required for basic fibroblast growth factor activity, Cell, 67, 229, 10.1016/0092-8674(91)90173-V

Klagsbrun, 1993, VEGF/VPF: the angiogenic factor found, Curr. Biol., 3, 699, 10.1016/0960-9822(93)90073-W

L’Heureux, 1998, A completely biological tissue-engineered human blood vessel, FASEB J., 12, 47, 10.1096/fasebj.12.1.47

Laham, 1999, Local perivascular delivery of basic fibroblast growth factor in patients undergoing coronary bypass surgery: results of a phase I randomized, double-blind, placebo-controlled trial, Circulation, 100, 1865, 10.1161/01.CIR.100.18.1865

Lammert, 2001, Induction of pancreatic differentiation by signals from blood vessels, Science, 294, 564, 10.1126/science.1064344

Levy, 1996, Hypoxia-inducible protein binding to vascular endothelial growth factor mRNA and its modulation by the von Hippel–Lindau protein, J. Biol. Chem., 271, 25492, 10.1074/jbc.271.41.25492

Levy, 1996, Post-transcriptional regulation of vascular endothelial growth factor by hypoxia, J. Biol. Chem., 271, 2746, 10.1074/jbc.271.5.2746

Mahoney, 1999, Millimeter-scale positioning of a nerve-growth-factor source and biological activity in the brain, Proc. Natl. Acad. Sci. USA, 96, 4536, 10.1073/pnas.96.8.4536

Matsumoto, 2001, Liver organogenesis promoted by endothelial cells prior to vascular function, Science, 294, 559, 10.1126/science.1063889

Mikos, 1993, Prevascularization of porous biodegradable polymers, Biotech. Bioeng., 42, 716, 10.1002/bit.260420606

Miyazawa, 1994, Proteolytic activation of hepatocyte growth factor in response to tissue injury, J. Biol. Chem., 269, 8966, 10.1016/S0021-9258(17)37062-X

Montesano, 1991, Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor, Cell, 67, 901, 10.1016/0092-8674(91)90363-4

Mooney, 1994, Transplantation of hepatocytes using porous, biodegradable sponges, Transplant. Proc., 26, 3425

Mooney, 1999, Growing new organs, Sci. Am., 280, 60, 10.1038/scientificamerican0499-60

Morimoto, 1991, Hepatocyte growth factor modulates migration and proliferation of human microvascular endothelial cells in culture, Biochem. Biophys. Res. Commun., 179, 1042, 10.1016/0006-291X(91)91924-2

Murphy, 2000, Sustained release of vascular endothelial growth factor from mineralized poly(lactide-co-glycolide) scaffolds for tissue engineering, Biomaterials, 21, 2521, 10.1016/S0142-9612(00)00120-4

Nakamura, 1991, Structure and function of hepatocyte growth factor, Prog. Growth Factor Res., 3, 67, 10.1016/0955-2235(91)90014-U

Nakamura, 1989, Molecular cloning and expression of human hepatocyte growth factor, Nature, 342, 440, 10.1038/342440a0

Naldini, 1991, Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor, EMBO J., 10, 2867, 10.1002/j.1460-2075.1991.tb07836.x

Niklason, 1999, Functional arteries grown in vitro, Science, 284, 489, 10.1126/science.284.5413.489

Nor, 1999, Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell survival and induction of Bcl-2 expression, Am. J. Pathol., 154, 375, 10.1016/S0002-9440(10)65284-4

Nor, 2001, Engineering and characterization of functional human microvessels in immunodeficient mice, Lab. Invest., 81, 453, 10.1038/labinvest.3780253

Park, 1993, The vascular endothelial growth factor (VEGF) isoforms: differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF, Mol. Biol. Cell, 4, 1317, 10.1091/mbc.4.12.1317

Pepper, 1997, Transforming growth factor-beta: vasculogenesis, angiogenesis, and vessel wall integrity, Cytokine Growth Factor Rev, 81, 21, 10.1016/S1359-6101(96)00048-2

Plate, 1993, Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis, Cancer Res., 53, 5822

Raines, 1991, Platelet-derived growth factor, 173

Richardson, 2001, Polymeric system for dual growth factor delivery, Nat. Biotechnol., 19, 1029, 10.1038/nbt1101-1029

Risau, 1997, Mechanisms of angiogenesis, Nature, 386, 671, 10.1038/386671a0

Risau, 1995, Vasculogenesis, Ann. Rev. Cell Develop. Biol., 11, 73, 10.1146/annurev.cb.11.110195.000445

Rivard, 1998, Angiogenesis and vasculogenesis in treatment of cardiovascular disease, Mol. Med., 4, 429, 10.1007/BF03401749

Rogelj, 1989, Basic fibroblast growth factor is an extracellular matrix component required for supporting the proliferation of vascular endothelial cells and the differentiation of PC12 cells, J. Cell Biol., 109, 823, 10.1083/jcb.109.2.823

Sato, 1995, Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation, Nature, 376, 70, 10.1038/376070a0

Sayers, 1998, Long-term results of femorotibial bypass with vein or polytetrafluoroethylene, Br. J. Surg., 85, 934, 10.1046/j.1365-2168.1998.00765.x

Schatteman, 2000, Blood-derived angioblasts accelerate blood-flow restoration in diabetic mice, J. Clin. Invest., 106, 571, 10.1172/JCI9087

Schechner, 2000, In vivo formation of complex microvessels lined by human endothelial cells in an immunodeficient mouse, Proc. Natl. Acad. Sci. USA, 97, 9191, 10.1073/pnas.150242297

Schmidt, 1995, Scatter factor/hepatocyte growth factor is essential for liver development, Nature, 373, 699, 10.1038/373699a0

Schultheiss, 2000, Tisssue engineering from Adam to the zygote: historical reflections, World J. Urol., 18, 84, 10.1007/s003450050015

Schumacher, 1998, Induction of neoangiogenesis in ischemic myocardium by human growth factors: first clinical results of a new treatment of coronary heart disease, Circulation, 97, 645, 10.1161/01.CIR.97.7.645

Shalaby, 1995, Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice, Nature, 376, 62, 10.1038/376062a0

Shea, 1999, DNA delivery from polymer matrices for tissue engineering, Nat. Biotechnol., 17, 551, 10.1038/9853

Shibuya, 1990, Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family, Oncogene, 5, 519

Shima, 1995, Hypoxic induction of endothelial cell growth factors in retinal cells: identification and characterization of vascular endothelial growth factor (VEGF) as the mitogen, Mol. Med., 1, 182, 10.1007/BF03401566

Shweiki, 1993, Patterns of expression of vascular endothelial growth factor (VEGF) and VEGF receptors in mice suggest a role in hormonally regulated angiogenesis, J. Clin. Invest., 91, 2235, 10.1172/JCI116450

Shweiki, 1992, Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis, Nature, 359, 843, 10.1038/359843a0

Skalak, 1988

Soker, 2001, Neuropilin in the midst of cell migration and retraction, Int. J. Biochem. Cell Biol., 33, 433, 10.1016/S1357-2725(01)00028-0

Soker, 1996, Characterization of novel vascular endothelial growth factor (VEGF) receptors on tumor cells that bind VEGF165 via its exon 7-encoded domain, J. Biol. Chem., 271, 5761, 10.1074/jbc.271.10.5761

Soker, 2000, Systems for therapeutic angiogenesis in tissue engineering, World J. Urol., 18, 10, 10.1007/PL00007070

Soker, 1998, Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor, Cell, 92, 735, 10.1016/S0092-8674(00)81402-6

Springer, 1998, VEGF gene delivery to muscle: potential role for vasculogenesis in adults, Mol. Cell., 2, 549, 10.1016/S1097-2765(00)80154-9

Takahashi, 1999, Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization, Nat. Med., 5, 434, 10.1038/8462

Takahashi, 1999, Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization, Nat. Med., 5, 434, 10.1038/8462

Takeshita, 1996, Gene transfer of naked DNA encoding for three isoforms of vascular endothelial growth factor stimulates collateral development in vivo, Lab. Invest., 75, 487

Takeshita, 1994, Therapeutic angiogenesis. A single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model, J. Clin. Invest., 93, 662, 10.1172/JCI117018

Terman, 1992, Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor, Biochem. Biophys. Res. Commun., 187, 1579, 10.1016/0006-291X(92)90483-2

Trusolino, 1998, Interactions between scatter factors and their receptors: hints for therapeutic applications, FASEB J., 12, 267, 10.1096/fasebj.12.13.1267

Tu, 1997, Use of cardiac procedures and outcomes in elderly patients with myocardial infarction in the United States and Canada, N. Engl. J. Med., 336, 1500, 10.1056/NEJM199705223362106

Uehara, 1995, Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor, Nature, 373, 702, 10.1038/373702a0

Vailhe, 2001, In vitro models of vasculogenesis and angiogenesis, Lab. Invest., 81, 439, 10.1038/labinvest.3780252

Van Belle, 1998, Potentiated angiogenic effect of scatter factor/hepatocyte growth factor via induction of vascular endothelial growth factor: the case for paracrine amplification of angiogenesis, Circulation, 97, 381, 10.1161/01.CIR.97.4.381

Veikkola, 1999, VEGFs, receptors and angiogenesis, Semin. Cancer Biol., 9, 211, 10.1006/scbi.1998.0091

Weinberg, 1986, A blood vessel model constructed from collagen and cultured vascular cells, Science, 231, 397, 10.1126/science.2934816

Yamashita, 2000, Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors, Nature, 408, 92, 10.1038/35040568

Yanagisawa-Miwa, 1992, Salvage of infarcted myocardium by angiogenic action of basic fibroblast growth factor, Science, 257, 1401, 10.1126/science.1382313

Yancopoulos, 2000, Vascular-specific growth factors and blood vessel formation, Nature, 407, 242, 10.1038/35025215

Yancopoulos, 1998, Vasculogenesis, angiogenesis, and growth factors: ephrins enter the fray at the border, Cell, 93, 661, 10.1016/S0092-8674(00)81426-9

Yang, 1999, Human endothelial cell life extension by telomerase expression, J. Biol. Chem., 274, 26141, 10.1074/jbc.274.37.26141

Yang, 2001, Telomerized human microvasculature is functional in vivo, Nat. Biotechnol., 19, 219, 10.1038/85655

Yayon, 1991, Cell surface, heparin-like molecules are required for binding basic fibroblast growth factor to its high affinity receptors, Cell, 64, 841, 10.1016/0092-8674(91)90512-W

Young, 1999, Chemoattraction of femoral CD34+ progenitor cells by tumor-derived vascular endothelial cell growth factor, Clin. Exp. Metastasis, 17, 881, 10.1023/A:1006708607666