Primary biliary cirrhosis and the nuclear pore complex

Autoimmunity Reviews - Tập 11 - Trang 898-902 - 2012
Carolina Duarte-Rey1,2, Dimitrios Bogdanos3, Chen-Yen Yang1, Krista Roberts1, Patrick S.C. Leung1, Juan-Manuel Anaya4, Howard J. Worman5,6, M. Eric Gershwin1
1Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis School of Medicine, Davis, CA, USA
2Departamento de Medicina Interna, Facultad de Medicina, Pontificia Universidad Javeriana, Bogotá, Colombia
3Institute of Liver Studies, Transplantation Immunology and Mucosal Biology, King's College London School of Medicine at King's College Hospital, London, UK
4Centro de Estudio de Enfermedades Autoinmunes, Facultad de Medicina, Universidad del Rosario, Bogotá, Colombia
5Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY, USA
6Department of Pathology and Cell Biology, College of Physicians and Surgeons, Columbia University, New York, NY, USA

Tài liệu tham khảo

Agmon-Levin, 2010, A comprehensive evaluation of serum autoantibodies in primary biliary cirrhosis, J Autoimmun, 34, 55, 10.1016/j.jaut.2009.08.009 Aringer, 2012, Therapeutic blockade of TNF in patients with SLE—promising or crazy?, Autoimmun Rev, 11, 321, 10.1016/j.autrev.2011.05.001 Belizna, 2010, Anti-Ku antibodies: clinical, genetic and diagnostic insights, Autoimmun Rev, 9, 691, 10.1016/j.autrev.2010.05.020 Bonaguri, 2011, Italian multicentre study for application of a diagnostic algorithm in autoantibody testing for autoimmune rheumatic disease: conclusive results, Autoimmun Rev, 11, 1, 10.1016/j.autrev.2011.06.006 Defendenti, 2011, Clinical and laboratory aspects of Ro/SSA-52 autoantibodies, Autoimmun Rev, 10, 150, 10.1016/j.autrev.2010.09.005 Lee, 2010, Transgenic overexpression of anti-double-stranded DNA autoantibody and activation of Toll-like receptor 4 in mice induce severe systemic lupus erythematosus syndromes, J Autoimmun, 35, 358, 10.1016/j.jaut.2010.07.007 Perl, 2010, Pathogenic mechanisms in systemic lupus erythematosus, Autoimmunity, 43, 1, 10.3109/08916930903374741 Szalat, 2010, Anti-NuMA1 and anti-NuMA2 (anti-HsEg5) antibodies: clinical and immunological features: a propos of 40 new cases and review of the literature, Autoimmun Rev, 9, 652, 10.1016/j.autrev.2010.05.001 Tan, 1966, Deoxybonucleic acid (DNA) and antibodies to DNA in the serum of patients with systemic lupus erythematosus, J Clin Invest, 45, 1732, 10.1172/JCI105479 Ullal, 2011, Microparticles as antigenic targets of antibodies to DNA and nucleosomes in systemic lupus erythematosus, J Autoimmun, 36, 173, 10.1016/j.jaut.2011.02.001 Wang, 2011, Enforced expression of the apoptosis inhibitor Bcl-2 ablates tolerance induction in DNA-reactive B cells through a novel mechanism, J Autoimmun, 37, 18, 10.1016/j.jaut.2011.03.002 Shoenfeld, 2005, Protective autoantibodies: role in homeostasis, clinical importance, and therapeutic potential, Arthritis Rheum, 52, 2599, 10.1002/art.21252 Meroni, 2008, Predictive, protective, orphan autoantibodies: the example of anti-phospholipid antibodies, Autoimmun Rev, 7, 585, 10.1016/j.autrev.2008.08.001 Forger, 2004, Clinical significance of anti-dsDNA antibody isotypes: IgG/IgM ratio of anti-dsDNA antibodies as a prognostic marker for lupus nephritis, Lupus, 13, 36, 10.1191/0961203304lu485oa Worman, 2007, Nuclear envelope protein autoantigens in primary biliary cirrhosis, Hepatol Res, 37, S406, 10.1111/j.1872-034X.2007.00227.x Bogdanos, 2008, Autoimmune liver serology: current diagnostic and clinical challenges, World J Gastroenterol, 14, 3374, 10.3748/wjg.14.3374 Bogdanos, 2011, Disease-specific autoantibodies in primary biliary cirrhosis, Clin Chim Acta, 412, 502, 10.1016/j.cca.2010.12.019 Courvalin, 1997, Nuclear envelope protein autoantibodies in primary biliary cirrhosis, Semin Liver Dis, 17, 79, 10.1055/s-2007-1007185 Worman, 2003, Antinuclear antibodies specific for primary biliary cirrhosis, Autoimmun Rev, 2, 211, 10.1016/S1568-9972(03)00013-2 Ruffatti, 1985, Nuclear membrane-staining antinuclear antibody in patients with primary biliary cirrhosis, J Clin Immunol, 5, 357, 10.1007/BF00918255 Lassoued, 1990, Antinuclear antibodies directed to a 200-kilodalton polypeptide of the nuclear envelope in primary biliary cirrhosis. A clinical and immunological study of a series of 150 patients with primary biliary cirrhosis, Gastroenterology, 99, 181, 10.1016/0016-5085(90)91246-3 Lassoued, 1988, Antinuclear autoantibodies specific for lamins. Characterization and clinical significance, Ann Intern Med, 108, 829, 10.7326/0003-4819-108-6-829 Lozano, 1988, Autoantibodies against nuclear envelope-associated proteins in primary biliary cirrhosis, Hepatology, 8, 930, 10.1002/hep.1840080438 Courvalin, 1990, Identification and characterization of autoantibodies against the nuclear envelope lamin B receptor from patients with primary biliary cirrhosis, J Exp Med, 172, 961, 10.1084/jem.172.3.961 Miyachi, 2003, Profile and clinical significance of anti-nuclear envelope antibodies found in patients with primary biliary cirrhosis: a multicenter study, J Autoimmun, 20, 247, 10.1016/S0896-8411(03)00033-7 Kraemer, 2003, Nucleoporin p62 antibodies in a case of mixed connective tissue disease, Clin Diagn Lab Immunol, 10, 329, 10.1128/CDLI.10.2.329-331.2003 Kraemer, 2010, Nuclear pore protein p62 autoantibodies in systemic lupus erythematosus, Open Rheumatol J, 4, 24, 10.2174/1874312901004010024 Hetzer, 2010, The nuclear envelope, Cold Spring Harb Perspect Biol, 2, a000539, 10.1101/cshperspect.a000539 Hoelz, 2011, The structure of the nuclear pore complex, Annu Rev Biochem, 80, 613, 10.1146/annurev-biochem-060109-151030 Macara, 2001, Transport into and out of the nucleus, Microbiol Mol Biol Rev, 65, 570, 10.1128/MMBR.65.4.570-594.2001 Hsia, 2007, Architecture of a coat for the nuclear pore membrane, Cell, 131, 1313, 10.1016/j.cell.2007.11.038 Alber, 2007, The molecular architecture of the nuclear pore complex, Nature, 450, 695, 10.1038/nature06405 Alber, 2007, Determining the architectures of macromolecular assemblies, Nature, 450, 683, 10.1038/nature06404 Callan, 1950, Experimental studies on amphibian oocyte nuclei. I. Investigation of the structure of the nuclear membrane by means of the electron microscope, Proc R Soc Lond B Biol Sci, 137, 367, 10.1098/rspb.1950.0047 Watson, 1959, Further observations on the nuclear envelope of the animal cell, J Biophys Biochem Cytol, 6, 147, 10.1083/jcb.6.2.147 Rout, 1993, Isolation of the yeast nuclear pore complex, J Cell Biol, 123, 771, 10.1083/jcb.123.4.771 Matunis, 1996, A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex, J Cell Biol, 135, 1457, 10.1083/jcb.135.6.1457 Davis, 1986, Identification and characterization of a nuclear pore complex protein, Cell, 45, 699, 10.1016/0092-8674(86)90784-1 DeGrasse, 2009, Evidence for a shared nuclear pore complex architecture that is conserved from the last common eukaryotic ancestor, Mol Cell Proteomics, 8, 2119, 10.1074/mcp.M900038-MCP200 Courvalin, 1990, The 210-kD nuclear envelope polypeptide recognized by human autoantibodies in primary biliary cirrhosis is the major glycoprotein of the nuclear pore, J Clin Invest, 86, 279, 10.1172/JCI114696 Nickowitz, 1994, Autoantibodies against integral membrane proteins of the nuclear envelope in patients with primary biliary cirrhosis, Gastroenterology, 106, 193, 10.1016/S0016-5085(94)95333-3 Wozniak, 1989, Primary structure analysis of an integral membrane glycoprotein of the nuclear pore, J Cell Biol, 108, 2083, 10.1083/jcb.108.6.2083 Greber, 1990, A major glycoprotein of the nuclear pore complex is a membrane-spanning polypeptide with a large lumenal domain and a small cytoplasmic tail, EMBO J, 9, 1495, 10.1002/j.1460-2075.1990.tb08267.x Favreau, 2001, Biochemical characterization of nuclear pore complex protein gp210 oligomers, Eur J Biochem, 268, 3883, 10.1046/j.1432-1327.2001.02290.x Nickowitz, 1993, Autoantibodies from patients with primary biliary cirrhosis recognize a restricted region within the cytoplasmic tail of nuclear pore membrane glycoprotein Gp210, J Exp Med, 178, 2237, 10.1084/jem.178.6.2237 Wesierska-Gadek, 1995, Autoantibodies from patients with primary biliary cirrhosis preferentially react with the amino-terminal domain of nuclear pore complex glycoprotein gp210, J Exp Med, 182, 1159, 10.1084/jem.182.4.1159 Bandin, 1996, Specificity and sensitivity of gp210 autoantibodies detected using an enzyme-linked immunosorbent assay and a synthetic polypeptide in the diagnosis of primary biliary cirrhosis, Hepatology, 23, 1020, 10.1002/hep.510230512 Itoh, 1998, Autoantibodies against a 210 kDa glycoprotein of the nuclear pore complex as a prognostic marker in patients with primary biliary cirrhosis, J Gastroenterol Hepatol, 13, 257, 10.1111/j.1440-1746.1998.01553.x Tartakovsky, 1995, Detection of Gp210 autoantibodies in primary biliary cirrhosis using a recombinant protein containing the predominant autoepitope, Hepatology, 21, 495 Mattalia, 1997, Persistence of autoantibodies against recombinant mitochondrial and nuclear pore proteins after orthotopic liver transplantation for primary biliary cirrhosis, J Autoimmun, 10, 491, 10.1006/jaut.1997.0156 Miyachi, 1996, Primary biliary cirrhosis sera recognize not only gp210 but also proteins of the p62 complex bearing N-acetylglucosamine residues from rat liver nuclear envelope. Anti-p62 complex antibody in PBC, Mol Biol Rep, 23, 227, 10.1007/BF00351173 Luettig, 1998, The antinuclear autoantibodies Sp100 and gp210 persist after orthotopic liver transplantation in patients with primary biliary cirrhosis, J Hepatol, 28, 824, 10.1016/S0168-8278(98)80233-X Nakamura, 2007, Anti-gp210 and anti-centromere antibodies are different risk factors for the progression of primary biliary cirrhosis, Hepatology, 45, 118, 10.1002/hep.21472 Nakamura, 2005, Antibody titer to gp210-C terminal peptide as a clinical parameter for monitoring primary biliary cirrhosis, J Hepatol, 42, 386, 10.1016/j.jhep.2004.11.016 Liu, 2010, PBC screen: an IgG/IgA dual isotype ELISA detecting multiple mitochondrial and nuclear autoantibodies specific for primary biliary cirrhosis, J Autoimmun, 35, 436, 10.1016/j.jaut.2010.09.005 Muratori, 2003, Characterization and clinical impact of antinuclear antibodies in primary biliary cirrhosis, Am J Gastroenterol, 98, 431, 10.1111/j.1572-0241.2003.07257.x Schwarz-Herion, 2007, Domain topology of the p62 complex within the 3-D architecture of the nuclear pore complex, J Mol Biol, 370, 796, 10.1016/j.jmb.2007.05.030 Guan, 1995, Structural analysis of the p62 complex, an assembly of O-linked glycoproteins that localizes near the central gated channel of the nuclear pore complex, Mol Biol Cell, 6, 1591, 10.1091/mbc.6.11.1591 Capelson, 2010, Nuclear pore complexes: guardians of the nuclear genome, Cold Spring Harb Symp Quant Biol, 75, 585, 10.1101/sqb.2010.75.059 Wesierska-Gadek, 1996, Autoantibodies against nucleoporin p62 constitute a novel marker of primary biliary cirrhosis, Gastroenterology, 110, 840, 10.1053/gast.1996.v110.pm8608894 Wesierska-Gadek, 2007, Characterization of autoantibodies against components of the nuclear pore complexes: high frequency of anti-p62 nucleoporin antibodies, Ann N Y Acad Sci, 1109, 519, 10.1196/annals.1398.058 Wesierska-Gadek, 2008, Characterization of the antibodies to p62 nucleoporin in primary biliary cirrhosis using human recombinant antigen, J Cell Biochem, 104, 27, 10.1002/jcb.21595 Ou, 2004, The nuclear pore complex protein Tpr is a common autoantigen in sera that demonstrate nuclear envelope staining by indirect immunofluorescence, Clin Exp Immunol, 136, 379, 10.1111/j.1365-2249.2004.02432.x Wesierska-Gadek, 2006, Correlation of initial autoantibody profile and clinical outcome in primary biliary cirrhosis, Hepatology, 43, 1135, 10.1002/hep.21172 Meda, 2009, Fine specificity of anti-nup62 T-helper 1 cell (TH1) immune responses in priumary biliary cirrhosis, J Hepatol, 50, S248, 10.1016/S0168-8278(09)60678-4 Invernizzi, 2001, Autoantibodies against nuclear pore complexes are associated with more active and severe liver disease in primary biliary cirrhosis, J Hepatol, 34, 366, 10.1016/S0168-8278(00)00040-4 Bogdanos, 2007, Anti-gp210 antibody mirrors disease severity in primary biliary cirrhosis, Hepatology, 45, 1583, 10.1002/hep.21678 Sfakianaki, 2010, Peri-nuclear antibodies correlate with survival in Greek primary biliary cirrhosis patients, World J Gastroenterol, 16, 4938, 10.3748/wjg.v16.i39.4938 Nakamura, 2006, Increased expression of nuclear envelope gp210 antigen in small bile ducts in primary biliary cirrhosis, J Autoimmun, 26, 138, 10.1016/j.jaut.2005.10.007 Kaplan, 2005, Primary biliary cirrhosis, N Engl J Med, 353, 1261, 10.1056/NEJMra043898 Neuberger, 1997, Primary biliary cirrhosis, Lancet, 350, 875, 10.1016/S0140-6736(97)05419-6 Neuberger, 2003, Liver transplantation for primary biliary cirrhosis: indications and risk of recurrence, J Hepatol, 39, 142, 10.1016/S0168-8278(03)00283-6 Neuberger, 2003, Liver transplantation for primary biliary cirrhosis, Autoimmun Rev, 2, 1, 10.1016/S1568-9972(02)00103-9 Dubel, 1998, Persistence of gp210 and multiple nuclear dots antibodies does not correlate with recurrence of primary biliary cirrhosis 6 years after liver transplantation, J Hepatol, 28, 169, 10.1016/S0168-8278(98)80220-1 Shimoda, 2003, Molecular mimicry of mitochondrial and nuclear autoantigens in primary biliary cirrhosis, Gastroenterology, 124, 1915, 10.1016/S0016-5085(03)00387-1