Primary Prevention of Ischemic Stroke

10.1161/str.29.2.415

American Heart Association. Stroke Statistics. Dallas Tex: American Heart Association; 2000. Available at: http://www.americanheart.org/Heart and Stroke A Z Guide/strokes.html. Accessed September 2000.>

American Heart Association. Economic Cost of Cardiovascular Diseases. Available at: http://www.americanheart.org/statistics/10econom.html. Accessed September 2000.

10.1001/archneur.1995.00540280029015

10.1161/str.28.7.1507

10.1161/str.25.1.8266381

10.1161/str.28.8.1527

Brown RD, Whisnant JP, Sicks JD, et al. Stroke incidence, prevalence, and survival: secular trends in Rochester, Minnesota, through 1989. Stroke. 1996;27:373–380.

10.1161/str.28.9.1840

10.1161/str.23.11.1440701

10.1093/oxfordjournals.aje.a009445

10.1161/circ.99.4.463

10.1056/NEJM199609123351102

10.1001/archneur.1997.00550140073015

10.1161/circ.96.7.2468

10.1161/str.29.12.2656

10.1161/str.25.11.7974531

10.1161/str.30.4.736

10.1001/archinte.1995.00430120109013

10.1159/000109685

10.1161/str.30.8.1711

10.1159/000026172

Deleted in proof.

10.1161/str.29.1.29

10.1161/str.26.12.2222

10.1056/NEJM198708273170901

10.1161/str.24.9.8362432

10.1161/str.28.10.1908

10.1056/NEJM198402163100706

10.1161/str.23.2.1561651

Wolf PA. Cerebrovascular risk. In: Izzo JL Jr Black HR Goodfriend TL et al. Hypertension Primer: The Essentials of High Blood Pressure. Baltimore Md: Lippincott Williams & Wilkins; 1999.

10.1016/0140-6736(90)90878-9

10.1161/01.HYP.25.3.305

10.1001/archinte.1997.00440420033005

10.1001/jama.1970.03170330025003

10.1001/jama.1967.03130240070013

10.1001/jama.1997.03540330061036

10.1016/S0140-6736(97)05381-6

10.1001/jama.1991.03460240051027

10.1161/hyp.26.1.60

10.1161/str.30.7.1312

10.1159/000026215

10.1016/0735-1097(93)90773-T

Cruickshank JM, Neil-Dwyer G, Dorrance DE, et al. Acute effects of smoking on blood pressure and cerebral blood flow. J Hum Hypertens. 1989;3:443–449.

10.1136/bmj.298.6676.789

10.1161/str.22.3.2003301

National Center for Health Statistics. Healthy People 2000 Review 1989–1999. Hyattsville Md: US Dept of Health and Human Services; 1999.

10.1001/jama.1993.03500020066033

10.7326/0003-4819-120-6-199403150-00002

10.1001/jama.1988.03720070025028

10.1001/jama.1995.03530020073035

10.1016/0735-1097(94)90315-8

10.1136/tc.8.2.156

10.1345/aph.13398

10.1016/S1098-3597(98)90015-1

10.1161/str.25.5.8165689

10.1001/jama.1979.03290450033020

10.1136/bmj.317.7160.703

10.1002/ana.410380607

10.1001/jama.1996.03540230036032

10.1016/S0140-6736(98)07037-8

10.1177/204748739900600409

10.1016/S0140-6736(99)12323-7

Guide to Clinical Preventive Services: Report of the US Preventive Services Task Force. 2nd ed. Baltimore Md: Williams & Wilkins; 1996.

American Diabetes Association. Clinical practice recommendations 1998. Diabetes Care. 1998;21(suppl 1):S1–S89.

10.1161/str.23.12.1448826

10.1212/WNL.44.6.1046

10.1056/NEJM198610023151404

10.1212/WNL.36.6.861

10.1001/jama.283.11.1429

10.1056/NEJM200006083422302

10.1016/S0140-6736(87)92861-3

10.1161/str.22.10.1926232

10.1016/S0025-6196(12)60456-X

10.1056/NEJM199301283280401

10.1001/jama.1995.03520420037035

10.1161/str.29.4.750

10.1161/str.26.9.1607

10.1161/str.28.5.889

10.1161/str.22.8.1866765

10.1161/circ.98.10.946

10.1016/S0140-6736(89)91200-2

Boston Area Anticoagulation Trial for Atrial Fibrillation Investigators. The effect of low-dose warfarin on the risk of stroke in patients with nonrheumatic atrial fibrillation. N Engl J Med. 1990;22:1505–1511.

10.1161/circ.84.2.1860198

10.1056/NEJM199211123272002

10.1016/0735-1097(91)90585-W

Laupacis A Albers G Dalen J et al. Antithrombotic therapy in atrial fibrillation. Chest. 1998;114(suppl):579S-589S.

10.1001/archinte.1994.00420130036007

Di Pasquale G Urbinati S Pinelli G. Cardiac investigation in patients with cerebrovascular disease. In: Ginsberg M Bogousslavsky J. Cerebrovascular Disease: Pathophysiology Diagnosis and Management. Malden Mass: Blackwell Science; 1998.

10.1002/ana.410160110

10.1097/00000658-198108000-00016

10.1161/str.20.6.2728043

10.1212/WNL.34.11.1403

10.1161/str.23.3.1542910

10.1161/str.28.5.941

10.1016/0002-9149(92)90930-W

10.1161/str.17.6.3810707

10.1097/00019052-199802000-00009

10.1161/circ.89.4.8149520

10.1056/NEJM199609123351103

10.1161/circ.99.18.2371

10.1016/S0003-4975(10)60352-9

10.1056/NEJM198811103191903

10.1016/0167-5273(92)90009-R

10.1016/S0022-5223(19)33877-2

10.1016/S0741-5214(95)70276-8

Newman MF Wolman R Kanchuger M et al. Multicenter preoperative stroke risk index for patients undergoing coronary artery bypass graft surgery: Multicenter Study of Perioperative Ischemia (MCSPI) Research Group. Circulation. 1996;94(suppl II):II-74–II-80.

10.1056/NEJM199612193352501

10.1016/S0735-1097(99)00606-3

Peterson ED Cowper PA Jollis JG et al. Outcomes of coronary artery bypass graft surgery in 24 461 patients aged 80 years or older. Circulation. 1995;92(suppl II):II-85–II-91.

10.1161/circ.100.6.642

10.1016/S0003-4975(99)00537-8

10.1016/S0002-8703(99)70191-2

10.1016/S0735-1097(99)00034-0

Adams RJ. Neurological complications. In: Embury S. Sickle Cell Disease: Scientific Principles and Clinical Practice. New York NY: Raven Press; 1994:599–621.

Ohene-Frempong K, Weiner SJ, Sleeper LA, et al. Cerebrovascular accidents in sickle cell disease: rates and risk factors. Blood. 1998;91:288–294.

10.1542/peds.97.6.864

10.1056/NEJM199202273260905

10.1002/ana.410420505

10.1056/NEJM199807023390102

10.1182/blood.V81.5.1109.bloodjournal8151109

10.1182/blood.V85.4.879.bloodjournal854879

10.1056/NEJM199505183322001

10.1016/S0140-6736(95)92836-7

10.1016/0091-7435(80)90017-1

10.1161/str.11.1.6444469

10.1136/bmj.309.6946.11

10.1161/str.25.4.8160226

10.1056/NEJM198904063201405

10.1136/bmj.303.6803.605

10.1159/000109885

Kargman DE, Tuck C, Berglund LF, et al. Elevated high density lipoprotein levels are more important in atherosclerotic ischemic stroke subtypes: the Northern Manhattan Stroke Study. Ann Neurol. 1998;44:442–443. Abstract.

Salonen R, Seppanen K, Rauramaa R, et al. Prevalence of carotid atherosclerosis and serum cholesterol levels in eastern Finland. Atherosclerosis. 1988;8:788–792.

10.1227/00006123-199009000-00001

10.1093/oxfordjournals.aje.a116078

10.7326/0003-4819-119-2-199307150-00008

10.1161/01.CIR.88.1.20

10.1161/circ.90.4.7734010

10.1016/S0002-9149(99)80580-3

10.7326/0003-4819-124-6-199603150-00002

Scandinavian Simvastatin Survival Study Group. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet. 1994;344:1383–1389.

10.1056/NEJM199610033351401

10.1056/NEJM199811053391902

10.1161/circ.92.9.2419

10.1001/jama.1997.03550040069040

10.1161/str.28.5.946

10.1056/NEJM199511163332001

10.1161/circ.99.2.216

Deleted in proof.

10.1161/atvb.19.2.187

10.1001/jama.279.20.1643

10.1161/str.28.11.2315

Endres M, Laufs U, Huang Z, et al. Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase. Proc Natl Acad Sci U S A. 1998;95:8880–8885.

10.1161/circ.100.3.230

10.1161/str.30.9.1969

10.1038/330132a0

10.1161/01.CIR.74.4.758

10.1161/circ.96.5.1390

10.1161/str.25.1.8266386

10.1177/000456329703400404

10.1177/204748739900600101

Glader CA, Stegmayr B, Boman J, et al. Chlamydia pneumoniae antibodies and high lipoprotein(a) levels do not predict ischemic cerebral infarctions: results from a nested case-control study in northern Sweden. Stroke. 1999;20:2013–2018.

10.1093/oxfordjournals.aje.a008892

10.1001/jama.1997.03540430051032

Fletcher GF. Exercise in the prevention of stroke. Health Rep. 1994;6:106–110.

10.1093/oxfordjournals.aje.a117094

10.1093/oxfordjournals.aje.a117298

10.1161/str.24.10.8378951

Manson JE Stampfer MJ Willett WC et al. Physical activity and incidence of coronary heart disease and stroke in women. Circulation. 1995;91(suppl):5. Abstract.>

10.1161/str.24.10.8378948

10.1093/oxfordjournals.aje.a008829

10.1161/str.29.2.380

10.1136/bmj.304.6827.597

10.1136/bmj.307.6898.231

10.1056/NEJM199511303332204

10.1001/jama.1996.03540030039029

10.1016/0140-6736(91)90664-B

10.1016/0895-4356(93)90111-D

10.1161/atvb.15.10.1668

10.1093/sleep/18.3.188

10.1056/NEJM199605163342004

10.1001/jama.1996.03540030075036

10.1001/jama.1995.03520290054029

10.7326/0003-4819-130-12-199906150-00003

10.1001/jama.282.13.1233

10.1001/jama.1986.03370170075038

10.1056/NEJM198808043190503

10.1161/str.13.1.7064181

10.1016/S0140-6736(78)92160-8

10.1161/str.20.12.2688193

10.1161/str.18.2.3564091

10.1161/str.19.11.3188119

10.1016/0002-9343(91)90610-A

10.1161/str.20.6.2728039

10.1161/str.24.12.8248963

10.1001/jama.281.1.53

10.1161/str.24.10.8378949

10.1056/NEJM198610233151701

10.7326/0003-4819-131-5-199909070-00008

10.1093/clinchem/44.2.311

10.1161/circ.99.1.178

10.1001/jama.1993.03510220049033

10.1093/ajcn/69.3.482

10.7326/0003-4819-131-5-199909070-00003

10.1001/jama.1995.03530130055028

10.1161/str.29.12.2473

10.7326/0003-4819-131-5-199909070-00006

10.1159/000026169

10.1038/sj.jhh.1000803

10.1001/archinte.160.4.422

10.1136/bmj.316.7135.894

10.1097/00043798-199808000-00007

10.7326/0003-4819-113-11-821

10.1056/NEJM199009133231102

10.1001/archneur.1989.00520450059019

10.1212/WNL.41.9.1358

10.1212/WNL.48.2.341

10.1212/WNL.50.6.1688

10.1212/WNL.50.4.890

10.1097/00001648-199811000-00005

10.1016/S0736-4679(99)00009-8

10.1001/archinte.159.16.1925

10.1056/NEJM199504133321504

10.7326/0003-4819-117-4-303

Bushnell CD, Goldstein LB. Ischemic stroke: recognizing risks unique to women. Womens Health Primary Care. 1999;2:788–804.>

10.1056/NEJM198510243131702

10.1016/0002-9343(94)90050-7

10.1056/NEJM199706193362501

10.1111/j.1471-0528.1987.tb03166.x

Rosenberg SH, Fausone V, Clark R. The role of estrogens as a risk factor for stroke in postmenopausal women. West J Med. 1980;133:292–296.

10.1001/archinte.1993.00410010097008

10.1001/archinte.1993.00410100035005

10.1097/00001648-199701000-00010

10.1056/NEJM199608153350701

10.1161/str.29.1.23

10.1001/archinte.1991.00400010095012

10.1136/bmj.297.6647.519

Petitti DB, Perlman JA, Sidney S. Noncontraceptive estrogens and mortality: long-term follow-up of women in the Walnut Creek Study. Obstet Gynecol. 1987;70:289–293.

10.1161/str.17.1.2868549

10.7326/0003-4819-117-12-1016

10.1001/jama.1975.03240190022010

10.1161/str.25.5.8165687

10.1136/bmj.306.6883.956

10.1016/S0140-6736(95)12393-8

10.7326/0003-4819-127-8_Part_1-199710150-00003

10.1056/NEJM199607043350102

10.1136/bmj.315.7121.1502

10.1016/S0140-6736(95)12393-8

10.1111/j.1471-0528.1995.tb09070.x

10.1001/jama.284.1.72

10.1161/res.85.2.199

10.1161/res.82.5.532

10.1006/bbrc.1995.1140

10.1172/JCI116778

10.1161/str.29.7.1405

10.1016/S0021-9150(99)00011-8

10.1161/str.29.8.1625

10.1161/atvb.18.11.1765

10.1161/circ.96.12.4219

10.1161/atvb.17.11.2646

10.1007/s100169900277

10.1016/S0002-8703(99)70294-2

10.1177/000331979704800805

10.1161/str.29.4.773

10.1161/circ.92.12.3397

10.1161/circ.100.8.832

10.1161/str.30.2.299

10.1016/0002-9343(93)90332-J

10.1161/str.29.2.404

10.1161/str.27.12.2207

10.1053/ejvs.1999.0915

10.1161/circ.98.25.2796

10.1056/NEJM199704033361401

10.1016/S0002-9149(99)00491-9

10.1161/circ.98.8.731

10.1161/circ.100.8.793

Feng D, Tracy RP, Lipinska I, et al. Effect of short-term aspirin use on C-reactive protein. J Thromb Thrombolysis. 2000;9:37–41.

10.1161/circ.98.9.839

10.1161/str.19.7.3388457

10.1161/str.25.9.8073477

10.1212/WNL.46.2.301

10.1016/S0741-5214(98)70355-6

10.1016/0741-5214(88)90073-0

10.1001/archinte.1997.00440320143013

10.1161/str.23.12.1448818

10.1161/str.23.6.1595098

10.1016/0741-5214(87)90224-2

10.1001/archneur.1992.00530320089016

Ahmed A Adams RJ. Sickle cell disorders and cerebrovascular disease. In: Gillum RF Gorelick PB Cooper ES eds. Stroke in Blacks: A Guide to Management and Prevention. Basel Switzerland: S. Karger AG; 1999:62–69.

10.1159/000109683

10.1001/jama.282.16.1519

10.1161/str.26.5.749

10.1016/0002-9378(89)90522-X

10.7326/0003-4819-120-6-199403150-00004

10.1111/j.1471-0528.1993.tb15105.x

10.1001/jama.1997.03540400055031

10.1055/s-0037-1614528

10.1055/s-0037-1614599

10.1016/S0140-6736(95)91803-5

10.1002/(SICI)1096-8652(199908)61:4<265::AID-AJH8>3.0.CO;2-#

Zoller B, Garcia de Frutos P, Hillarp A, et al. Thrombophilia as a multigenic disease. Haematologica. 1999;84:59–70.

10.1055/s-0037-1614563

Cooper DN Krawczak M. Venous Thrombosis: From Genes to Clinical Medicine. Oxford UK: BIOS Scientific Publishers Ltd; 1997.>

10.1055/s-0038-1655963

10.1212/WNL.38.9.1359

10.1161/str.17.3.2940735

10.1159/000040854

10.1055/s-0037-1615049

10.1055/s-0038-1653730

10.1111/j.1365-2141.1994.tb04878.x

10.1212/WNL.43.10.2069

10.1111/j.1600-0447.1995.tb09545.x

10.1017/S0317167100033515

10.1161/str.30.8.1561

10.1016/S0022-510X(97)00071-3

Brey RL, Abbott RD, Sharp DS, et al. Beta-2-glycoprotein 1-dependent (B2GP1-dep) anticardiolipin antibodies (aCL) are an independent risk factor for ischemic stroke in the Honolulu Heart Cohort. Stroke. 1999;30:252. Abstract.

10.1182/blood.V90.9.3806

10.1016/S0049-3848(98)00154-6

10.1161/atvb.19.7.1751

10.1056/NEJM199504063321403

10.1097/00001721-199710000-00004

10.1182/blood.V92.2.704

10.1161/circ.99.8.999

10.1046/j.1365-2141.1997.3943208.x

10.1182/blood.V91.10.3562

10.1161/circ.100.7.736

10.1016/S0010-7824(98)00032-8

10.1161/str.29.2.554

10.1001/archneur.1997.00550130015009

10.1001/jama.1993.03500230097036