Priapism Following Trazodone Overdose with Cocaine Use

Annals of Clinical Psychiatry - Tập 10 - Trang 81-83 - 1998
Hugh Myrick1, John S. Markowitz1, Scott Henderson1
1The Institute of Psychiatry, The Medical University of South Carolina, Charleston

Tóm tắt

Priapism is a urologic disorder and medical emergency with a variety of known etiologies including the use of psychotropic medications. The antidepressant trazodone is the agent most frequently implicated in the precipitation of priapism. Additionally, a number of drugs of abuse including marijuana, ethanol, and cocaine have been known to cause the disorder. It is unknown if drugs may act in an additive or a synergistic manner to cause priapism. We report a case of priapism which occurred following trazodone overdose in an individual actively using cocaine. This case suggests that combined trazodone and cocaine use may pose an additional risk of priapism. Since trazodone is commonly employed as a hypnotic and often chosen for polysubstance abusers due to its low abuse potential, clinicians should be aware of the possible additive risk of priapism in this patient population.

Tài liệu tham khảo

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