Ross, 1999, Atherosclerosis-an inflammatory disease, N Engl J Med, 340, 115, 10.1056/NEJM199901143400207
Grundy, 1990, Coronary heart disease in high-risk populations: lessons from Finland, Eur Heart J, 11, 462, 10.1093/oxfordjournals.eurheartj.a059730
Stamler, 1986, Is the relationship between serum cholesterol and risk of premature death from coronary heart disease continuous and graded? Findings in 356,222 primary screenees of the Multiple Risk Factor Intervention Trial (MRFIT), JAMA, 256, 2823, 10.1001/jama.1986.03380200061022
Superko, 1994, Coronary artery disease regression: convincing evidence for the benefit of aggressive lipoprotein management, Circulation, 90, 1056, 10.1161/01.CIR.90.2.1056
Ballantyne, 1997, Effects of lipid-lowering therapy on progression of coronary and carotid artery disease, Curr Opin Lipidol, 8, 354, 10.1097/00041433-199712000-00006
Superko, 1996, What can we learn about dense LDL and lipoprotein particles from clinical trials?, Curf Opin Lipidol, 7, 363, 10.1097/00041433-199612000-00004
Superko, 1996, Beyond LDL reduction, Circulation, 94, 2351, 10.1161/01.CIR.94.10.2351
1994, Randomized trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S), Lancet, 344, 1383
Shepherd, 1995, Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia, N Engl J Med, 333, 1301, 10.1056/NEJM199511163332001
Sacks, 1996, The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels, N Engl J Med, 335, 1001, 10.1056/NEJM199610033351401
Downs, 1998, Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS, JAMA, 279, 1615, 10.1001/jama.279.20.1615
1998, Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels, N Engl J Med, 339, 1349, 10.1056/NEJM199811053391902
1998, Influence of pravastatin and plasma lipids on clinical events in the West of Scotland Coronary Prevention Study, Circulation, 97, 1440, 10.1161/01.CIR.97.15.1440
Sacks, 1998, Relationship between plasma LDL concentrations during treatment with pravastatin and recurrent coronary events in the Cholesterol and Recurrent Events trial, Circulation, 97, 1446, 10.1161/01.CIR.97.15.1446
Grundy, 1998, Statin trials and goals of cholesterol-lowering therapy, Circulation, 97, 1436, 10.1161/01.CIR.97.15.1436
Castelli, 1986, Incidence of coronary heart disease and lipoprotein-cholesterol levels: The Framingham Study, JAMA, 256, 2835, 10.1001/jama.1986.03380200073024
Superko, 1995, New aspects of cardiovascular risk factors including small, dense LDL, homocysteine, and Lp(a), Curr Opin Cardiol, 10, 347, 10.1097/00001573-199507000-00002
Pahor, 1999, Emerging noninvasive biochemical measures to predict cardiovascular risk, Arch Intern Med, 159, 237, 10.1001/archinte.159.3.237
Liao, 1998, Endothelium and the acute coronary syndromes, Clin Chem, 44, 1799, 10.1093/clinchem/44.8.1799
Lagrand, 1999, C-reactive protein as a cardiovascular risk factor: more than an epiphenomenon?, Circulation, 100, 96, 10.1161/01.CIR.100.1.96
Libby, 1997, Roles of infectious agents in atherosclerosis and restenosis, Circulation, 96, 4095, 10.1161/01.CIR.96.11.4095
Kannel, 1995, Range of serum cholesterol values in the population developing coronary artery disease, Am J Cardiol, 76, 69C, 10.1016/S0002-9149(99)80474-3
Grundy, 1997, atherogenic dyslipidemia, and the metabolic syndrome, Circulation, 95, 1, 10.1161/01.CIR.95.1.1
Otvos, 1999, Measurement of triglyceride-rich lipoproteins by nuclear magnetic resonance spectroscopy, Clin Cardiol, 22, II
Albrink, 1959, Serum triglycerides in coronary artery disease, Arch Intern Med, 103, 4, 10.1001/archinte.1959.00270010010002
Goldstein, 1973, Hyperlipidemia in coronary heart disease, I: lipid levels in 500 survivors of myocardial infarction, J Clin Invest, 52, 1533, 10.1172/JCI107331
Castelli, 1977, HDL cholesterol and other lipids in coronary heart disease: The Cooperative Lipoprotein Phenotyping Study, Circulation, 55, 767, 10.1161/01.CIR.55.5.767
Carlson, 1979, Risk factors for myocardial infarction in the Stockholm Prospective Study: a l4-year follow-up focusing on the role of plasma triglyceride and cholesterol, Acta Med Scand, 206, 351, 10.1111/j.0954-6820.1979.tb13526.x
Gotto, 1977, Relationship between plasma lipid concentration and coronary artery disease in 496 patients, Circulation, 56, 875, 10.1161/01.CIR.56.5.875
Sprecher, 1998, Triglycerides as a risk factor for coronary artery disease, Am J Cardiol, 82, 49U, 10.1016/S0002-9149(98)00953-9
Gotto, 1998, Triglycerides as a risk factor for coronary artery disease, Am J Cardiol, 82, 22Q, 10.1016/S0002-9149(98)00770-X
Packard, 1999, Physiology of the lipoprotein transport system: an overview of lipoprotein metabolism, 17
Ginsberg, 1999, VLDL/LDL cascade system: assembly, secretion, and intravascular metabolism of apoprotein B-containing lipoproteins, 55
Yamashita, 1999, Cholesteryl ester transfer protein, 277
Eisenberg, 1999, High-density lipoprotein metabolism, 71
Brunzell, 1989, Familial lipoprotein lipase deficiency and other causes of the chylomicronemia syndrome, 1165
Gerdes, 1995, Polymorphisms in the lipoprotein lipase and their associations with plasma lipid concentration in 40-year-old Danish men, Circulation, 92, 1765, 10.1161/01.CIR.92.7.1765
Tall, 1986, Plasma lipid transfer proteins, J Lipid Res, 27, 361, 10.1016/S0022-2275(20)38819-2
Krauss, 1994, Heterogeneity of plasma low-density lipoproteins and atherosclerosis risk, Cuff Opin Lipidol, 5, 339, 10.1097/00041433-199410000-00005
Krauss, 1998, Atherogenicity of triglyceride-rich lipoproteins, Am J Cardiol, 81, 13B, 10.1016/S0002-9149(98)00032-0
Hodis, 1999, Pathophysiology of triglyceriderich lipoproteins in atherothrombosis: clinical aspects, Clin Cardiol, 22, II
Hodis, 1999, Triglyceride-rich lipoprotein remnants and risk of atherosclerosis, Circulation, 99, 2852, 10.1161/01.CIR.99.22.2852
Alaupovic, 1991, Apolipoprotein composition as the basis for classifying plasma lipoproteins, Prog Lipid Res, 30, 105, 10.1016/0163-7827(91)90008-S
Grundy, 1992, Two different views of the relationship of hypertriglyceridemia to coronary heart disease: implications for treatment, Arch Intern Med, 152, 28, 10.1001/archinte.1992.00400130054004
Gianturco, 1999, Pathophysiology of triglyceride-rich lipoproteins in atherothrombosis: cellular aspects, Clin Cardiol, 22, II
Benlian, 1996, Premature atherosclerosis in patients with familial chylomicronemia caused by mutations in the lipoprotein lipase gene, N Engl J Med, 335, 848, 10.1056/NEJM199609193351203
Anderson, 1999, Association of lipoprotein lipase gene polymorphisms with coronary artery disease, J Am Coll Cardiol, 33, 1013, 10.1016/S0735-1097(98)00677-9
Wittrup, 1999, Lipoprotein lipase mutations, plasma lipids and lipoproteins, and risk of ischemic disease: a meta-analysis, Circulation, 99, 2901, 10.1161/01.CIR.99.22.2901
Gofman, 1966, Ischemic heart disease, atherosclerosis, and longevity, Circulation, 34, 679, 10.1161/01.CIR.34.4.679
Gofman, 1954, The serum lipoprotein transport system in health, metabolic disorders, atherosclerosis, and coronary disease, Plasma, 2, 413
Lindgren, 1951, The ultracentrifugal characterization and isolation of human blood lipids and lipoproteins with applications to the study of atherosclerosis, J Phys Colloid Chem, 55, 80, 10.1021/j150484a010
Chung, 1991, Cytotoxicity of remnants of triglyceride-rich lipoproteins: an atherogenic insult, Adv Exp Med Biol, 285, 341, 10.1007/978-1-4684-5904-3_42
Schaefer, 1986, Familial apolipoprotein E deficiency, J Clin Invest, 78, 1206, 10.1172/JCI112704
Mahley, 1995, Type III hyperlipidemia (dysbetalipoproteinemia): The role of apolipoprotein E in normal and abnormal lipoprotein metabolism, 1953
Frost, 1998, Rationale for use of non-high-density lipoprotein cholesterol rather than low-density lipoprotein cholesterol as a tool for lipoprotein cholesterol screening and assessment of risk and therapy, Am J Cardiol, 81, 26B, 10.1016/S0002-9149(98)00034-4
Krauss, 1987, Intermediate-density lipoproteins and progression of coronary artery disease in hypercholesterolemic men, Lancet, 2, 62, 10.1016/S0140-6736(87)92734-6
Krauss, 1987, Relationship of intermediate and low-density lipoprotein subspecies to risk of coronary artery disease, Am Heart J, 113, 578, 10.1016/0002-8703(87)90636-3
Grundy, 1998, Consensus statement: role of therapy with “statins” in patients with hypertriglyceridemia, Am J Cardiol, 81, 1B, 10.1016/S0002-9149(98)00030-7
Grundy, 1998, Hypertriglyceridemia, atherogenic dyslipidemia, and the metabolic syndrome, Am J Cardiol, 81, 18B, 10.1016/S0002-9149(98)00033-2
Austin, 1990, Atherogenic lipoprotein phenotype: A proposed genetic marker for coronary heart disease risk, Circulation, 82, 495, 10.1161/01.CIR.82.2.495
Austin, 1994, Characterization of low-density lipoprotein subclasses: methodologic approaches and clinical relevance, Curr Opin Lipidol, 5, 395, 10.1097/00041433-199412000-00002
Superko, 1998, Small dense LDL: the new coronary artery disease risk factor and how it is changing the treatment of CAD, Prev Cardiol, 1, 16
Reaven, 1993, Insulin resistance and hyperinsulinemia in individuals with small, dense, low-density lipoprotein particles, J Clin Invest, 92, 141, 10.1172/JCI116541
Austin, 1995, Prospective study of small LDLs as a risk factor for non-insulin-dependent diabetes mellitus in elderly men and women, Circulation, 92, 1770, 10.1161/01.CIR.92.7.1770
1994, Second Report of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II), Circulation, 89, 1329
Gordon, 1990, Role of circulating high-density lipoprotein and triglycerides in coronary artery disease: risk and prevention, Endocrinol Metabol Clin North Am, 19, 299, 10.1016/S0889-8529(18)30326-8
Miller, 1992, Long-term predictors of subsequent cardiovascular events with coronary artery disease and “desirable” levels of plasma total cholesterol, Circulation, 86, 1165, 10.1161/01.CIR.86.4.1165
Burchfiel, 1995, Combined effects of HDL cholesterol, triglyceride, and total cholesterol concentrations on 18-year risk of atherosclerotic disease, Circulation, 92, 1430, 10.1161/01.CIR.92.6.1430
Corti, 1995, HDL cholesterol predicts coronary heart disease mortality in older persons, JAMA, 274, 539, 10.1001/jama.1995.03530070037026
Paunio, 1994, HDL cholesterol and mortality in Finnish men with special reference to alcohol intake, Circulation, 90, 2909, 10.1161/01.CIR.90.6.2909
Atger, 1995, Highdensity lipoprotein subfractions as markers of early atherosclerosis, Am J Cardiol, 75, 127, 10.1016/S0002-9149(00)80060-0
Lien, 1996, Low-serum, highdensity lipoprotein cholesterol concentration is an important coronary risk factor in Chinese patients with low serum levels of total cholesterol and triglyceride, Am J Cardiol, 77, 1112, 10.1016/S0002-9149(96)00144-0
Frost, 1996, Coronary heart disease risk factors in men and women aged 60 years and older, Circulation, 94, 26, 10.1161/01.CIR.94.1.26
Austin, 1991, Plasma triglyceride and coronary heart disease, Arterioscler Thromb, 11, 2, 10.1161/01.ATV.11.1.2
Criqui, 1993, Plasma triglyceride level and mortality from coronary heart disease, N Engl J Med, 328, 1220, 10.1056/NEJM199304293281702
Criqui, 1998, Epidemiologic aspects of lipid abnormalities, Am J Med, 105, 48S, 10.1016/S0002-9343(98)00212-5
Gardner, 1996, Association of small low-density lipoprotein particles with the incidence of coronary artery disease in men and women, JAMA, 276, 875, 10.1001/jama.1996.03540110029028
Miller, 1975, Plasma high-density lipoprotein concentration and development of ischemic heart disease, Lancet, 1, 16, 10.1016/S0140-6736(75)92376-4
Gordon, 1977, High-density lipoprotein as a protective factor against coronary heart disease: the Framingham Study, Am J Med, 62, 707, 10.1016/0002-9343(77)90874-9
Hokanson, 1996, Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: a metaanalysis of population-based prospective studies, J Cardiovasc Risk, 3, 213, 10.1097/00043798-199604000-00014
Byberg, 1998, Plasminogen activator inhibitor-1 activity is independently related to both insulin sensitivity and serum triglycerides in 70-year-old men, Arterioscler Thromb Vasc Biol, 18, 258, 10.1161/01.ATV.18.2.258
Miller, 1986, Association between dietary fat intake and plasma factor VII coagulant activity—a predictor of cardiovascular mortality, Atherosclerosis, 60, 269, 10.1016/0021-9150(86)90174-7
Miller, 1985, Assay of factor VII activity by two techniques: evidence for increased conversion of VII to alpha VIIa in hyperlipidemia with possible implications for ischemic heart disease, Br J Haematol, 59, 249, 10.1111/j.1365-2141.1985.tb02991.x
Miller, 1991, Plasma factor VII is activated by postprandial triglyceridemia, irrespective of dietary fat composition, Atherosclerosis, 86, 163, 10.1016/0021-9150(91)90212-L
Green, 1994, Hemostatic factors in the Coronary Artery Risk Development in Young Adults (CARDIA) Study, Arterioscler Thromb, 14, 686, 10.1161/01.ATV.14.5.686
Mussoni, 1992, Hypertriglyceridemia and regulation of fibrinolytic activity, Arterioscler Thromb, 12, 19, 10.1161/01.ATV.12.1.19
Simpson, 1983, Hypertriglyceridemia and hypercoagulability, Lancet, I, 786, 10.1016/S0140-6736(83)91849-4
Vogel, 1997, Effect of a single high-fat meal on endothelial function in healthy subjects, Am J Cardiol, 79, 350, 10.1016/S0002-9149(96)00760-6
Patsch, 1992, Relation of triglyceride metabolism and coronary artery disease: studies in the postprandial state, Arterioscler Thromb, 12, 1336, 10.1161/01.ATV.12.11.1336
Sharrett, 1995, Association of postprandial triglyceride and retinyl palmitate responses with asymptomatic carotid artery atherosclerosis in middle-aged men and women: the Atherosclerosis Risk in Communities (ARIC) Study, Arterioscler Thromb Vase Biol, 15, 2122, 10.1161/01.ATV.15.12.2122
Karpe, 1994, Postprandial lipoproteins and progression of coronary atherosclerosis, Atherosclerosis, 106, 83, 10.1016/0021-9150(94)90085-X
Uiterwaal, 1994, Postprandial triglyceride response in young adult men and familial risk for coronary atherosclerosis, Ann Intern Med, 121, 576, 10.7326/0003-4819-121-8-199410150-00004
Karpe, 1999, Differences in postprandial concentrations of very-low density lipoprotein and chylomicron remnants between normotriglyceridemic and hypertriglyceridemic men with and without coronary heart disease, Metabolism, 48, 301, 10.1016/S0026-0495(99)90076-8
Marx, 1995, Does gemfibrozil prevent coronary disease by reduction of postprandial triglyceride-rich lipoproteins? Differences between triglyceride/HDL subgroups, Circulation, 92, I
O'Keefe, 1995, Effects of pravastatin with niacin or magnesium on lipid levels and postprandial lipemia, Am J Cardiol, 76, 480, 10.1016/S0002-9149(99)80134-9
Nikkila, 1994, Postprandial plasma lipoprotein changes in relation to apolipoprotein E phenotypes and low-density lipoprotein size in men with and without coronary heart disease, Atherosclerosis, 106, 149, 10.1016/0021-9150(94)90120-1
Ginsberg, 1995, Association of postprandial triglyceride and retinyl palmitate responses with newly diagnosed exercise-induced myocardial ischemia in middle-aged men and women, Arterioscler Thromb Vase Biol, 15, 1829, 10.1161/01.ATV.15.11.1829
Schaefer, 1994, Familial lipoprotein disorders and premature coronary artery disease, Med Clin North Am, 78, 21, 10.1016/S0025-7125(16)30175-4
Janus, 1980, Kinetic bases of the primary hyperlipidemias: studies of apolipoprotein B turnover in genetically defined subjects, Eur J Clin Invest, 10, 161, 10.1111/j.1365-2362.1980.tb02076.x
Kissebah, 1981, Integrated regulation of very low-density lipoprotein, triglycerides, and apolipoprotein-B kinetics in man: normolipemic subjects, familial hypertriglyceridemia, and familial combined hyperlipidemia, Metabolism, 30, 856, 10.1016/0026-0495(81)90064-0
Genest, 1992, Familial lipoprotein disorders in patients with premature coronary artery disease, Circulation, 85, 2025, 10.1161/01.CIR.85.6.2025
Goldstein, 1973, Hyperlipidemia in coronary heart disease: II—genetic analysis of lipid levels in 176 families and delineation of a new inherited disorder, combined hyperlipidemia, J Clin Invest, 52, 1544, 10.1172/JCI107332
Stone, 1998, Management of lipids in clinical practice, 60
Castelli, 1988, Cholesterol and lipids in the risk of coronary artery disease: the Framingham Heart Study, Can J Cardiol, 4, 5A
Hulley, 1980, Epidemiology as a guide to clinical decisions: the association between triglyceride and coronary heart disease, N Engl J Med, 302, 1383, 10.1056/NEJM198006193022503
Assmann, 1992, Role of triglycerides in coronary disease: lessons from the Prospective Cardiovascular Muenster Study, Am J Cardiol, 70, 10H, 10.1016/0002-9149(92)91084-H
Assmann, 1992, Relation of high-density lipoprotein cholesterol and triglycerides to incidence of atherosclerotic coronary artery disease (The PROCAM experience), Am J Cardiol, 70, 733, 10.1016/0002-9149(92)90550-I
Castelli, 1992, Epidemiology of triglycerides: a view from Framingham, Am J Cardiol, 70, 3H, 10.1016/0002-9149(92)91083-G
Bainton, 1992, Plasma triglyceride and high-density lipoprotein cholesterol as predictors of ischemic heart disease in British men: the Caerphilly and Speedwell Collaborative Heart Disease Studies, Br Heart J, 68, 60, 10.1136/hrt.68.7.60
Assmann, 1996, Hypertriglyceridemia and elevated lipoprotein (a) are risk factors for major coronary events in middle-aged men, Am J Cardiol, 77, 1179, 10.1016/S0002-9149(96)00159-2
Jeppesen, 1998, Triglyceride concentration and ischemic heart disease: an eight-year follow-up in the Copenhagen Male Study, Circulation, 97, 1029, 10.1161/01.CIR.97.11.1029
Cambien, 1986, Is the level of serum triglyceride a significant predictor of coronary death in “normocholesterolemic” subjects?, Am J Epidemiol, 124, 624, 10.1093/oxfordjournals.aje.a114435
Miller, 1998, Normal triglyceride levels and coronary artery disease events: the Baltimore Coronary Observational Long-Term Study, J Am Coll Cardiol, 31, 1252, 10.1016/S0735-1097(98)00083-7
Austin, 1998, Hypertriglyceridemia as a cardiovascular risk factor, Am J Cardiol, 81, 7B, 10.1016/S0002-9149(98)00031-9
1993, Summary of the Second Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II), JAMA, 269, 3015, 10.1001/jama.1993.03500230097036
Miller, 1999, The epidemiology of triglycerides as a coronary artery disease risk factor, Clin Cardiol, 22, II-1, 10.1002/clc.4960221402
Tailleux, 1996, HDL heterogeneity and atherosclerosis, Crit Rev Clin Lab Sci, 33, 163, 10.3109/10408369609083060
Fielding, 1995, Molecular physiology of reverse cholesterol transport, J Lipid Res, 36, 211, 10.1016/S0022-2275(20)39898-9
O'Connor, 1998, Pre-beta-1 HDL in plasma of normolipidemic individuals: Influences of plasma lipoproteins, age and gender, J Lipid Res, 39, 670, 10.1016/S0022-2275(20)33304-6
Tall, 1998, An overview of reverse cholesterol transport, Eur Heart J, 19, A31
Acton, 1996, Identification of scavenger receptor SR-BI as a high-density lipoprotein receptor, Science, 271, 518, 10.1126/science.271.5248.518
Krieger, 1998, The “best” of cholesterols, the “worst” of cholesterols: a tale of two receptors, 95, 4077
Kwiterovich, 1998, The anti-atherogenic role of high-density lipoprotein cholesterol, Am J Cardiol, 82, 13Q, 10.1016/S0002-9149(98)00808-X
Dansky, 1999, High-density lipoprotein and plaque regression: the good cholesterol gets even better, Circulation, 100, 1762, 10.1161/01.CIR.100.17.1762
Tangirala, 1999, Regression of atherosclerosis induced by liver-directed gene transfer of apolipoprotein A-I in mice, Circulation, 100, 1816, 10.1161/01.CIR.100.17.1816
Parthasarathy, 1990, High-density lipoprotein inhibits the oxidative modification of low-density lipoprotein, Biochem Biophys Acta, 1044, 275, 10.1016/0005-2760(90)90314-N
Saku, 1985, Activation of fibrinolysis by apolipoproteins of high-density lipoproteins in man, Thromb Res, 39, 1, 10.1016/0049-3848(85)90116-1
Barter, 1996, High-density lipoproteins and coronary heart disease, Atherosclerosis, 121, 1, 10.1016/0021-9150(95)05675-0
Havel, 1973, Interchange of apolipoproteins between chylomicrons and high-density lipoproteins during alimentary lipemia in man, J Clin Invest, 52, 32, 10.1172/JCI107171
Gordon, 1989, High-density lipoprotein cholesterol and cardiovascular disease: four prospective American series, Circulation, 79, 8, 10.1161/01.CIR.79.1.8
Castelli, 1992, Lipids and risk of coronary heart disease: The Framingham Study, Ann Epidemiol, 2, 23, 10.1016/1047-2797(92)90033-M
Genest, 1992, Lipoprotein cholesterol, apolipoprotein A-1 and B, and Lipoprotein (a) abnormalities in men with premature coronary artery disease, J Am Coll Cardiol, 19, 792, 10.1016/0735-1097(92)90520-W
Castelli, 1977, HDL cholesterol and other lipids in coronary heart disease: the Cooperative Lipoprotein Phenotyping Study, Circulation, 55, 767, 10.1161/01.CIR.55.5.767
Pearson, 1979, The association of low levels of HDL cholesterol and arteriographically defined coronary artery disease, Am J Epidemiol, 109, 285, 10.1093/oxfordjournals.aje.a112682
Shah, 1992, Low, high-density lipoprotein level is associated with increased re-stenosis rate after coronary angioplasty, Circulation, 85, 1279, 10.1161/01.CIR.85.4.1279
Dzavik, 1995, Effect of serum lipid concentration on re-stenosis after successful de novo percutaneous transluminal coronary angioplasty in patients with total cholesterol 160–240 mg/dL and triglycerides <350 mg/dL, Am J Cardiol, 75, 936, 10.1016/S0002-9149(99)80691-2
Burke, 1997, Coronary risk factors and plaque morphology in men with coronary disease who died suddenly, N Engl J Med, 336, 1276, 10.1056/NEJM199705013361802
Rubins, 1999, Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol, N Engl J Med, 341, 410, 10.1056/NEJM199908053410604
Laakso, 1985, Association of low HDL and HDL2 cholesterol with coronary heart disease in non-insulin-dependent diabetics, Arteriosclerosis, 5, 653, 10.1161/01.ATV.5.6.653
Hamsten, 1986, Relationship of angiographically defined coronary heart disease to serum lipoproteins and apolipoproteins in young survivors of myocardial infarction, Circulation, 73, 1097, 10.1161/01.CIR.73.6.1097
Franceschini, 1987, Reduced HDL2 levels in myocardial infarction patients without risk factors for atherosclerosis, Atherosclerosis, 68, 213, 10.1016/0021-9150(87)90200-0
Ballantyne, 1982, High density and low density lipoprotein subfractions in survivors of myocardial infarction and in control subjects, Metabolism, 31, 433, 10.1016/0026-0495(82)90230-X
Stampfer, 1991, A prospective study of cholesterol, apolipoproteins, and the risk of myocardial infarction, N Engl J Med, 325, 373, 10.1056/NEJM199108083250601
Salonen, 1991, HDL, HDL2, and HDL3 subfractions, and the risk of acute myocardial infarction: a prospective population study in Eastern Finnish men, Circulation, 84, 129, 10.1161/01.CIR.84.1.129
Nichols, 1986, Nondenaturing polyacrylamide gradient gel electrophoresis, Methods Enzymol, 128, 417, 10.1016/0076-6879(86)28084-2
Wilson, 1993, Alterations in the concentration of an apolipoprotein E-containing subfraction of plasma high-density lipoprotein in coronary heart disease, Clin Chim Acta, 220, 175, 10.1016/0009-8981(93)90046-7
Johansson, 1991, High-density lipoproteins and coronary atherosclerosis: a strong inverse relation with the largest particles is confined to normotriglyceridemic patients, Arterioscler Thromb, 11, 174, 10.1161/01.ATV.11.1.174
Wilson, 1990, The distribution of high-density lipoprotein subfractions in coronary survivors, Biochem Soc Trans, 18, 1175, 10.1042/bst0181175
Cheung, 1991, Altered particle size distribution of apolipoprotein A-1-containing lipoproteins in subjects with coronary artery disease, J Lipid Res, 32, 383, 10.1016/S0022-2275(20)42061-9
Fievet, 1991, HDL heterogeneity and coronary heart disease, Diabetes Metab Rev, 7, 155, 10.1002/dmr.5610070304
Miller, 1987, Associations of high-density lipoprotein subclasses and apolipoproteins with ischemic heart disease and coronary atherosclerosis, Am Heart J, 113, 589, 10.1016/0002-8703(87)90638-7
Williams, 1992, Associations of lipoproteins and apolipoproteins with gradient gel electrophoresis estimates of high density lipoprotein subfractions in men and women, Arterioscler Thromb Vasc Biol, 12, 232, 10.1161/01.ATV.12.3.332
Otvos, 1992, Development of a proton nuclear magnetic resonance spectroscopic method for determining plasma lipoprotein concentrations and subspecies distributions from a single, rapid measurement, Clin Chem, 38, 1622, 10.1093/clinchem/38.9.1632
Freedman, 1998, Relation of lipoprotein subclasses as measured by proton nuclear magnetic spectroscopy to coronary artery disease, Arterioscler Thromb Vasc Biol, 18, 1046, 10.1161/01.ATV.18.7.1046
Stampfer, 1996, A prospective study of triglyceride level, low-density lipoprotein particle diameter, and risk of myocardial infarction, JAMA, 276, 882, 10.1001/jama.1996.03540110036029
Sweetnam, 1994, Associations of the HDL2 and HDL3 cholesterol subfractions with the development of ischemic heart disease in British men: the Caerphilly and Speedwell Collaborative Heart Disease Studies, Circulation, 90, 769, 10.1161/01.CIR.90.2.769
Lamarche, 1997, Associations of HDL2 and HDL3 with ischemic heart disease in men: prospective results for the Quebec Cardiovascular Study, Arterioscler Thromb Vasc Biol, 17, 1098, 10.1161/01.ATV.17.6.1098
Lagrost, 1994, Combined effects of lipid transfers and lipolysis on gradient gel patterns of human plasma LDL, Arterioscler Thromb, 14, 1327, 10.1161/01.ATV.14.8.1327
McNamara, 1992, Change in LDL particle size is associated with change in plasma triglyceride concentration, Arterioscler Thromb, 12, 1284, 10.1161/01.ATV.12.11.1284
Coresh, 1993, Association of plasma triglyceride concentration and LDL particle diameter, density, and chemical composition with premature coronary artery disease in men and women, J Lipid Res, 34, 1687, 10.1016/S0022-2275(20)35731-X
Austin, 1995, Prospective study of small LDLs as a risk factor for non-insulin dependent diabetes mellitus in elderly men and women, Circulation, 92, 1770, 10.1161/01.CIR.92.7.1770
Musliner, 1986, Presence of multiple subpopulations of lipoproteins of intermediate density in normal subjects, Arteriosclerosis, 6, 79, 10.1161/01.ATV.6.1.79
Zambon, 1993, Effect of hepatic lipase on LDL in normal men and those with coronary artery disease, Arterioscler Thromb, 13, 147, 10.1161/01.ATV.13.2.147
Austin, 1986, Genetic control of low-density lipoprotein subclasses, Lancet, 2, 592, 10.1016/S0140-6736(86)92425-6
Austin, 1992, Genetic epidemiology of low-density lipoprotein subclass phenotypes, Ann Med, 24, 477, 10.3109/07853899209166999
Campos, 1992, LDL particle size distribution: results from the Framingham Offspring Study, Arterioscler Thromb, 12, 1410, 10.1161/01.ATV.12.12.1410
Selby, 1993, LDL subclass phenotypes and the insulin resistance syndrome in women, Circulation, 88, 381, 10.1161/01.CIR.88.2.381
Tall, 1990, Plasma high-density lipoproteins. Metabolism and relationship to atherogenesis, J Clin Invest, 86, 379, 10.1172/JCI114722
Dixon, 1991, Oleic acid stimulates secretion of ApoB-containing lipoproteins from HepG2 cells by reducing intracellular degradation of ApoB, J Biol Chem, 266, 5080, 10.1016/S0021-9258(19)67758-6
Randle, 1963, The glucose fatty-acid cycle: its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus, Lancet, 1, 785, 10.1016/S0140-6736(63)91500-9
Campos, 1991, Variations in hepatic lipase and lipoprotein lipase activities associated with low-density lipoprotein subclass patterns, Circulation, 84, 11
Campos, 1992, Low-density lipoprotein particle size and coronary artery disease, Arterioscler Thromb, 12, 187, 10.1161/01.ATV.12.2.187
Austin, 1988, Low-density lipoprotein subclass patterns and risk of myocardial infarction, JAMA, 260, 1917, 10.1001/jama.1988.03410130125037
Crouse, 1985, Studies of low-density lipoprotein molecular weight in human beings with coronary artery disease, J Lipid Res, 26, 566, 10.1016/S0022-2275(20)34343-1
Tornvall, 1991, Relationships of low density lipoprotein subfractions to angiographically defined coronary artery disease in young survivors of myocardial infarction, Atherosclerosis, 90, 67, 10.1016/0021-9150(91)90245-X
Stampfer, 1996, A prospective study of triglyceride level, low-density lipoprotein particle diameter, and risk of myocardial infarction, JAMA, 276, 882, 10.1001/jama.1996.03540110036029
Gardner, 1996, Association of small low-density lipoprotein particles with the incidence of coronary artery disease in men and women, JAMA, 276, 875, 10.1001/jama.1996.03540110029028
Lamarche, 1997, Small, dense low-density lipoprotein particles as a predictor of the risk of ischemic heart disease in men: prospective results from the Quebec Cardiovascular Study, Circulation, 95, 69, 10.1161/01.CIR.95.1.69
DeGraaf, 1991, Enhanced susceptibility to in vitro oxidation of the dense low-density lipoprotein subfraction in healthy subjects, Arterioscler Thromb, 11, 298, 10.1161/01.ATV.11.2.298
Tribble, 1992, Variations in oxidative susceptibility among six low-density lipoprotein subfractions of differing density and particle size, Atherosclerosis, 93, 189, 10.1016/0021-9150(92)90255-F
Chait, 1993, Susceptibility of small, dense, lowdensity lipoproteins to oxidative modification in subjects with the atherogenic lipoprotein phenotype, pattern B, Am J Med, 94, 350, 10.1016/0002-9343(93)90144-E
Dejager, 1993, Dense, low-density lipoprotein subspecies with diminished oxidative resistance predominate in combined hyperlipidemia, J Lipid Res, 34, 295, 10.1016/S0022-2275(20)40756-4
Dyce, 1993, Indices of LDL particle size closely relate to endothelial function, Circulation, 88, I-466
Anderson, 1996, Endothelium-dependent coronary vasomotion relates to the susceptibility of LDL to oxidation in humans, Circulation, 93, 1647, 10.1161/01.CIR.93.9.1647
Selwyn, 1997, Atherogenic lipids, vascular dysfunction, and clinical signs of ischemic heart disease, Circulation, 95, 5, 10.1161/01.CIR.95.1.5
Nielsen, 1996, Transfer of low-density lipoprotein into the arterial wall and risk of atherosclerosis, Atherosclerosis, 123, 1, 10.1016/0021-9150(96)05802-9
Bjomheden, 1996, Accumulation of lipoprotein fractions and subfractions in the arterial wall, determined in an in vitro perfusion system, Atherosclerosis, 123, 43, 10.1016/0021-9150(95)05770-6
Coresh, 1996, Small, dense, low-density lipoprotein particles and coronary heart risk: a clear association with uncertain implications, JAMA, 276, 914, 10.1001/jama.1996.03540110068034
Austin, 1999, Low-density lipoprotein particle size is a risk factor for coronary heart disease independent of triglyceride and HDL cholesterol: a meta-analysis of three prospective studies in men, Circulation, 99, I-1124
Austin, 1992, Bimodality of plasma apolipoprotein B levels in familial combined hyperlipidemia, Atherosclerosis, 92, 67, 10.1016/0021-9150(92)90011-5
Teng, 1983, Composition and distribution of low-density lipoprotein fractions in hyperapobetalipoproteinemia normolipidemia, and familial hypercholesterolemia, 80, 6662
Genest, 1993, Familial hypoalphalipoproteinemia in premature coronary artery disease, Arterioscler Thromb, 13, 1728, 10.1161/01.ATV.13.12.1728
Brown, 1996, Impact of management in stabilization of coronary disease, 191
Fuster, 1992, The pathogenesis of coronary artery disease and the acute coronary syndromes, N Engl J Med, 326, 242, 10.1056/NEJM199201233260406
Fuster, 1992, The pathogenesis of coronary artery disease and the acute coronary syndromes, N Engl J Med, 326, 310, 10.1056/NEJM199201303260506
Brown, 1993, Lipid lowering and plaque regression: New insights into prevention of plaque disruption and clinical events in coronary disease, Circulation, 87, 1781, 10.1161/01.CIR.87.6.1781
Brensike, 1984, Effects of therapy with cholestyramine on progression of coronary arteriosclerosis: results of the NHLBI Type II Coronary Intervention Study, Circulation, 69, 313, 10.1161/01.CIR.69.2.313
Miller, 1993, Baseline triglyceride levels predict angiographic benefit of colestipol plus niacin therapy in the Cholesterol-Lowering Atherosclerosis Study (CLAS), Circulation, 88, I
Hodis, 1995, Triglyceride-rich lipoproteins and the progression of coronary artery disease, Curf Opin Lipidol, 6, 209, 10.1097/00041433-199508000-00004
Blankenhorn, 1990, Prediction of angiographic change in native human coronary arteries and aortocoronary bypass grafts: lipid and non-lipid factors, Circulation, 81, 470, 10.1161/01.CIR.81.2.470
Blankenhorn, 1987, Beneficial effects of combined colestipol-niacin therapy on coronary atherosclerosis and coronary venous bypass grafts, JAMA, 257, 3233, 10.1001/jama.1987.03390230069027
Cashin-Hemphill, 1990, Beneficial effects of colestipol-niacin on coronary atherosclerosis: a four-year followup, JAMA, 264, 3013, 10.1001/jama.1990.03450230049028
Koren, 1996, Triglyceride-enriched lipoprotein particles correlate with the severity of coronary artery disease, Atherosclerosis, 122, 105, 10.1016/0021-9150(95)05791-9
Phillips, 1993, Plasma lipoproteins and progression of coronary artery disease evaluated by angiography and clinical events, Circulation, 88, 2762, 10.1161/01.CIR.88.6.2762
Mack, 1996, Lipoprotein subclasses in the Monitored Atherosclerosis Regression Study (MARS): treatment effects and relation to coronary angiographic progression, Arterioscler Thromb Vase Biol, 16, 697, 10.1161/01.ATV.16.5.697
Hodis, 1994, Triglyceride- and cholesterol-rich lipoproteins have a differential effect on mild/moderate and severe lesion progression as assessed by quantitative coronary angiography in a controlled trial of lovastatin, Circulation, 90, 42, 10.1161/01.CIR.90.1.42
Blankenhorn, 1993, Coronary angiographic changes with lovastatin therapy: the Monitored Atherosclerosis Regression Study (MARS), Ann Intern Med, 119, 969, 10.7326/0003-4819-119-10-199311150-00002
Alaupovic, 1997, The role of triglyceride-rich lipoprotein families in the progression of atherosclerosic lesions as determined by sequential coronary angiography from a controlled clinical trial, Arterioscler Thromb Vasc Biol, 17, 715, 10.1161/01.ATV.17.4.715
Miller, 1994, Predominance of mid-density/low-density lipoproteins predicts angiographic benefit of lovastatin in the Monitored Atherosclerosis Regression Study, Circulation, 90, I
Hodis, 1997, Intermediate-density lipoproteins and progression of carotid arterial wall intimamedia thickness, Circulation, 95, 2022, 10.1161/01.CIR.95.8.2022
Watts, 1992, Effects on coronary artery disease of lipid-lowering diet, or diet plus cholestyramine, in the St. Thomas' Atherosclerosis Regression Study (STARS), Lancet, 339, 563, 10.1016/0140-6736(92)90863-X
Watts, 1993, Independent associations between plasma lipoprotein subfraction levels and the course of coronary artery disease in the St. Thomas' Atherosclerosis Regression Study (STARS), Metabolism, 42, 1461, 10.1016/0026-0495(93)90199-X
Miller, 1996, Predominance of dense, low-density lipoprotein particles predicts angiographic benefit of therapy in the Stanford Coronary Risk Intervention Project, Circulation, 94, 2146, 10.1161/01.CIR.94.9.2146
Haskell, 1994, The effects of intensive multiple risk factor reduction on coronary atherosclerosis and clinical events in men and women with coronary artery disease: the Stanford Coronary Risk Intervention Project (SCRIP), Circulation, 89, 975, 10.1161/01.CIR.89.3.975
Zambon, 1996, Hepatic lipase changes predicts coronary artery disease regression/progression in the Familial Atherosclerosis Treatment Study, Circulation, 94, I
Stewart, 1994, Benefits of lipid-lowering therapy in men with elevated apolipoprotein B are not confined to those with very high low-density lipoprotein cholesterol, J Am Coll Cardiol, 23, 899, 10.1016/0735-1097(94)90635-1
Brown, 1998, Very intensive lipid therapy with lovastatin, niacin, and colestipol for prevention of death and myocardial infarction: a 10-year Familial Atherosclerosis Treatment Study (FATS) follow-up, Circulation, 98, I
West, 1996, The Lipoprotein and Coronary Atherosclerosis Study (LCAS): design, methods, and baseline data of a trial of fluvastatin in patients without severe hypercholesterolemia, Control Clin Trials, 17, 550, 10.1016/S0197-2456(96)00178-X
Herd, 1997, Effects of fluvastatin on coronary atherosclerosis in patients with mild-tomoderate cholesterol elevations (Lipoprotein and Coronary Atherosclerosis Study-LCAS), Am J Cardiol, 80, 278, 10.1016/S0002-9149(97)00346-9
Ballantyne, 1999, Influence of low HDL on progression of coronary artery disease and response to fluvastatin therapy, Circulation, 99, 736, 10.1161/01.CIR.99.6.736
Frick, 1997, Prevention of the angiographic progression of coronary and vein-graft atherosclerosis by gemfibrozil after coronary bypass surgery in men with low levels of HDL cholesterol: Lopid Coronary Angiography Trial (LOCAT) Study Group, Circulation, 96, 2137, 10.1161/01.CIR.96.7.2137
Ericsson, 1996, Angiographic assessment of effects of bezafibrate on progression of coronary artery disease in young male postinfarction patients, Lancet, 347, 849, 10.1016/S0140-6736(96)91343-4
Ruotolo, 1998, J Am Card Cardiol, 32, 1648, 10.1016/S0735-1097(98)00442-2
Austin, 1987, Low-density lipoprotein subclass patterns and risk of myocardial infarction: the Boston Area Health Study, Am J Epidemiol, 126, 739
Carlson, 1988, Reduction of mortality in the Stockholm Ischaemic Heart Disease Secondary Prevention Study by combined treatment with clofibrate and nicotinic acid, Acta Med Scanda, 223, 405, 10.1111/j.0954-6820.1988.tb15891.x
Frick, 1987, Helsinki Heart Study: primary prevention trial with gemfibrozil in middle-aged men with dyslipidemia: safety of treatment, changes in risk factors, and incidence of coronary heart disease, N Engl J Med, 317, 1237, 10.1056/NEJM198711123172001
Manninen, 1988, Lipid alterations and decline in the incidence of coronary heart disease in the Helsinki Heart Study, JAMA, 260, 641, 10.1001/jama.1988.03410050061031
Manninen, 1992, Joint effects of serum triglycerides and LDL cholesterol and HDL cholesterol concentrations on coronary heart disease risk in the Helsinki Heart Study: implications for treatment, Circulation, 85, 37, 10.1161/01.CIR.85.1.37
Sacks, 1998, New lipoprotein predictors of recurrent coronary events: VLDL particle concentration, VLDL lipid content, and apolipoproteins C-III and E, Circulation, 98, I
1995, Baseline serum cholesterol and treatment effect in the Scandinavian Simvastatin Survival Study (4S), Lancet, 345, 1274, 10.1016/S0140-6736(95)90926-5
Kesaniemi, 1998, Serum triglycerides and clinical benefit in lipid-lowering trials, Am J Cardiol, 814A, 70B, 10.1016/S0002-9149(98)00042-3
Pedersen, 1998, Lipoprotein changes and reduction in the incidence of major coronary heart disease events in, Circulation, 97, 1453, 10.1161/01.CIR.97.15.1453
Ferguson, 1999, Bezafibrate Infarction Prevention Trial, 99, 1131
Goldbourt, 1993, Rationale and design of a secondary prevention trial of increasing serum high-density lipoprotein cholesterol and reducing triglycerides in patients with clinically manifest atherosclerotic heart disease (The Bezafibrate Infarction Prevention Trial), Am J Cardiol, 71, 909, 10.1016/0002-9149(93)90905-R
1998, 40, 117
Stone, 1999, 2, 1
Vega, 1990, Management of primary mixed hyperlipidemia with lovastatin, Arch Intern Med, 150, 1313, 10.1001/archinte.1990.00390180119022
Vega, 1990, Primary hypertriglyceridemia with borderline high cholesterol and elevated apolipoprotein B concentrations, JAMA, 264, 2759, 10.1001/jama.1990.03450210059033
Grundy, 1988, HMG-CoA reductase inhibitors for treatment of hypercholesterolemia, N Engl J Med, 319, 24, 10.1056/NEJM198807073190105
Ginsberg, 1998, Effects of statins on triglyceride metabolism, Am J Cardiol, 81 A, 32B, 10.1016/S0002-9149(98)00035-6
Vega, 1998, Effect of statins on metabolism of apo-B-containing lipoproteins in hypertriglyceridemic men, Am J Cardiol, 81 A, 36B, 10.1016/S0002-9149(98)00036-8
Stein, 1998, Comparison of statins in hypertriglyceridemia, Am J Cardiol, 81 A, 66B, 10.1016/S0002-9149(98)00041-1
Cabezas, 1993, Simvastatin improves chylomicron remnant removal in familial combined hyperlipidemia without changing chylomicron conversion, Metab Clin Exp, 42, 497, 10.1016/0026-0495(93)90109-2
Vega, 1990, Pravastatin therapy in primary moderate hypercholesterolaemia: changes in metabolism of apolipoprotein B-containing lipoproteins, J Intern Med, 227, 81, 10.1111/j.1365-2796.1990.tb00124.x
Mitropoulos, 1997, Randomized placebo-controlled study of the effects of simvastatin on haemostatic variables, lipoproteins and free fatty acids: the Oxford Cholesterol Study Group, Eur Heart J, 18, 235, 10.1093/oxfordjournals.eurheartj.a015225
Contacos, 1993, Effect of pravastatin and omega-3 fatty acids on plasma lipids and lipoproteins in patients with combined hyperlipidemia, Arterioscler Thromb, 13, 1755, 10.1161/01.ATV.13.12.1755
Cheung, 1993, Effects of pravastatin on apolipoprotein-specific, high-density lipoprotein subpopulations and low-density lipoprotein subclass phenotypes in patients with primary hypercholesterolemia, Atherosclerosis, 102, 107, 10.1016/0021-9150(93)90089-D
Superko, 1997, Effect of HMG-CoA reductase inhibitor (fluvastatin) on LDL peak particle diameter, Am J Cardiol, 80, 78, 10.1016/S0002-9149(97)00288-9
Franceschini, 1994, Pravastatin effectively lowers LDL cholesterol in familial-combined hyperlipidemia without changing LDL subclass pattern, Arterioscler Thromb, 14, 1569, 10.1161/01.ATV.14.10.1569
Yuan, 1991, Effects of fluvastatin (XU 62–320), an HMG-CoA reductase inhibitor, on the distribution and composition of lowdensity lipoprotein subspecies in humans, Atherosclerosis, 87, 147, 10.1016/0021-9150(91)90017-W
Viterbo, 1992, Low-density lipoprotein particle size changes with lovastatin treatment, Clin Res, 40, 219A
Zhao, 1991, Effect of simvastatin on the apparent size of LDL particles in patients with type IIB hyperlipoproteinemia, Clin Chim Acta, 203, 109, 10.1016/0009-8981(91)90283-I
Gaw, 1993, Effects of Simvastatin on ApoB metabolism and LDL subfraction distribution, Arterioscler Thromb, 13, 170, 10.1161/01.ATV.13.2.170
de Graaf, 1993, The effect of simvastatin treatment on the low-density lipoprotein subfraction profile and composition in familial hypercholesterolaemia, Neth J Med, 43, 254
Rosenson, 1998, Effects of pravastatin treatment on lipoprotein subclass profiles and particle size in the PLAC-1 Trial, Circulation, 98, I
Carpentier, 1998, Atorvastatin substantially reduces small dense LDL subpopulation in patients with coronary heart disease, Circulation, 98, I
Homma, 1995, Effects of simvastatin on plasma lipoprotein subtractions, cholesterol esterification rate, and cholesterol ester transfer protein in type II hyperlipoproteinemia, Atherosclerosis, 114, 223, 10.1016/0021-9150(94)05487-4
Athyros, 1997, Safety and efficacy of long-term statin-fibrate combinations in patients with refractory familial combined hyperlipidemia, Am J Cardiol, 80, 608, 10.1016/S0002-9149(97)00430-X
Murdock, 1999, Long-term safety and efficacy of combination gemfibrozil and HMG-CoA reductase inhibitors for the treatment of mixed lipid disorders, Am Heart J, 138, 151, 10.1016/S0002-8703(99)70261-9
Grundy, 1976, Chylomicron clearance in normal and hyperlipidemic man, Metabolism, 25, 1225, 10.1016/S0026-0495(76)80006-6
Garg, 1990, Nicotinic acid as therapy for dyslipidemia in non-insulindependent diabetes mellitus, JAMA, 264, 723, 10.1001/jama.1990.03450060069031
Grundy, 1981, Influence of nicotinic acid on metabolism of cholesterol and triglycerides in man, J Lipid Res, 22, 24, 10.1016/S0022-2275(20)34737-4
Guyton, 1998, Effect of niacin on atherosclerotic cardiovascular disease, Am J Cardiol, 82, 18U, 10.1016/S0002-9149(98)00767-X
1975, Clofibrate and niacin in coronary heart disease, JAMA, 231, 360, 10.1001/jama.1975.03240160024021
Canner, 1986, Fifteen-year mortality in coronary drug project patients: long-term benefit with niacin, J Am Coll Cardiol, 8, 1245, 10.1016/S0735-1097(86)80293-5
Brown, 1990, Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B, N Engl J Med, 323, 1289, 10.1056/NEJM199011083231901
Morgan, 1996, Treatment effect of niaspan, a controlled-release niacin, in patients with hypercholesterolemia: a placebo-controlled trial, J Cardiovasc Pharmacol, 1, 195, 10.1177/107424849600100302
Guyton, 1998, Effectiveness of once-nightly dosing of extended-release niacin alone and in combination for hypercholesterolemia, Am J Cardiol, 82, 737, 10.1016/S0002-9149(98)00448-2
Morgan, 1998, A new extended-release niacin (Niaspan): efficacy, tolerability, and safety in hypercholesterolemic patients, Am J Cardiol, 82, 29U, 10.1016/S0002-9149(98)00732-2
Knopp, 1998, Clinical profiles of plain versus sustained-release niacin (Niaspan) and the physiologic rationale for nighttime dosing, Am J Cardiol, 82, 24U, 10.1016/S0002-9149(98)00847-9
Kashyap, 1998, Mechanistic studies of high-density lipoproteins, Am J Cardiol, 82, 42U, 10.1016/S0002-9149(98)00813-3
Vega, 1985, Gemfibrozil therapy in primary hypertriglyceridemia associated with coronary heart disease: effects on metabolism of low-density lipoproteins, JAMA, 253, 2398, 10.1001/jama.1985.03350400082026
Superko, 1992, Differential effects of nicotinic acid in subjects with different LDL subclass patterns, Atherosclerosis, 95, 69, 10.1016/0021-9150(92)90177-I
Superko, 1994, KOS Investigators. Effect of nicotinic acid on LDL subclass patterns, Circulation, 90, I
Superko, 1995, Reduction of small, dense LDL by gemfibrozil in LDL subclass pattern B, Circulation, 92, I
Zambon, 1998, Common variants in the promoter of the hepatic lipase gene are associated with lower levels of hepatic lipase activity, buoyant LDL, and higher HDL2 cholesterol, Arterioscler Thromb Vasc Biol, 18, 1723, 10.1161/01.ATV.18.11.1723
Capuzzi, 1998, Advances in dyslipidemia, Am J Cardiol, 82, 850
Egan, 1999, Rationale and design of the Arterial Disease Multiple Intervention Trial (ADMIT) Pilot Study, Am J Cardiol, 83, 569, 10.1016/S0002-9149(98)00915-1
Saku, 1985, Mechanism of action of gemfibrozil on lipoprotein metabolism, J Clin Invest, 75, 1702, 10.1172/JCI111879
Superko, 1997, LDL subclass distribution change in familial combined hyperlipidemia patients following gemfibrozil and niacin treatment, J Am Coll Cardiol, 29, 46A
Gaw, 1999, Fibric acid derivatives, 1145
Yuan, 1994, Changes in composition and distribution of LDL subspecies in hypertriglyceridemic and hypercholesterolemic patients during gemfibrozil therapy, Atherosclerosis, 110, 1, 10.1016/0021-9150(94)90062-0
Dachet, 1995, Effect of gemfibrozil on the concentration and composition of very-low-density and low-density lipoprotein subfractions in hypertriglyceridemic patients, Atherosclerosis, 113, 1, 10.1016/0021-9150(94)05411-B
De Lorgeril, 1999, Lipid-lowering drugs and homocysteine, Lancet, 353, 209, 10.1016/S0140-6736(05)77220-2
East, 1988, Combination drug therapy for familial combined hyperlipidemia, Ann Intern Med, 109, 25, 10.7326/0003-4819-109-1-25
Garg, 1989, Gemfibrozil alone and in combination with lovastatin for treatment of hypertriglyceridemia in NIDDM, Diabetes, 38, 364, 10.2337/diabetes.38.3.364
Barrett-Connor, 1991, Estrogen and coronary heart disease in women, JAMA, 265, 1861, 10.1001/jama.1991.03460140089033
Guetta, 1996, Cardiovascular effects of estrogen and lipid-lowering therapies in postmenopausal women, Circulation, 93, 1928, 10.1161/01.CIR.93.10.1928
1995, Effects of estrogen or estrogen/progestin regimens on heart disease risk factors in postmenopausal women: the Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial, JAMA, 273, 199, 10.1001/jama.1995.03520270033028
Darling, 1997, Estrogen and progestin compared with simvastatin for hypercholesterolemia in postmenopausal women, N Engl J Med, 337, 595, 10.1056/NEJM199708283370903
Tikkanen, 1999, Sex hormones, 967
Mosca, 1997, Cardiovascular disease in women, Circulation, 96, 2468, 10.1161/01.CIR.96.7.2468
Hulley, 1998, Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women, JAMA, 280, 605, 10.1001/jama.280.7.605
Lewis, 1998, Effect of pravastatin on cardiovascular events in women after myocardial infarction: the Cholesterol and Recurrent Events (CARE) Trial, J Am Coll Cardiol, 32, 140, 10.1016/S0735-1097(98)00202-2
Walsh, 1999, Lipids: natural history and pharmacologic management, 101
Von Schacky, 1999, The effect of dietary omega-3 fatty acids on coronary atherosclerosis, Ann Intern Med, 130, 554, 10.7326/0003-4819-130-7-199904060-00003
Burr, 1989, Effects of changes in fat, fish and fibre intakes on death and myocardial infarction: Diet and Reinfarction Trial (DART), Lancet, 2, 757, 10.1016/S0140-6736(89)90828-3
Burr, 1994, Diet and reinfarction, Eur Heart J, 15, 1152, 10.1093/oxfordjournals.eurheartj.a060645
Singh, 1997, Randomized, double-blind, placebo-controlled trial of fish oil and mustard oil in patients with suspected acute myocardial infarction: The Indian experiment of infarct survival-4, Cardiovasc Drug Ther, 11, 485, 10.1023/A:1007757724505
Harris, 1999, Nonpharmacologic treatment of hypertriglyceridemia: focus on fish oils, Clin Cardiol, 22, II-40, 10.1002/clc.4960221408
1999, GISSI-Prevenzione Investigators. Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione Trial, Lancet, 354, 447, 10.1016/S0140-6736(99)07072-5
Von Schacky, 1985, Long-term effects of dietary marine omega3 fatty acids upon plasma and cellular lipids, platelet function, and eicosanoid formation in humans, J Clin Invest, 76, 1626, 10.1172/JCI112147
Katan, 1995, Fish and heart disease, N Engl J Med, 332, 1024, 10.1056/NEJM199504133321509
Sniderman, 1996, Measurement of apoproteins: time to improve the diagnosis and treatment of the atherogenic dyslipoproteinemias, Clin Chem, 42, 489, 10.1093/clinchem/42.4.489
Rifai, 1992, Measurement of low-density lipoprotein cholesterol in serum: a status report, Clin Chem, 38, 150, 10.1093/clinchem/38.1.150
Kinosian, 1995, Cholesterol and coronary heart disease: predicting risks in men by changes in levels and ratios, J Investig Med, 43, 443
Kinosian, 1994, Cholesterol and coronary heart disease: Predicting risks by levels and ratios, Ann Intern Med, 121, 641, 10.7326/0003-4819-121-9-199411010-00002
Gaziano, 1997, Fasting triglycerides, high-density lipoprotein, and risk of myocardial infarction, Circulation, 96, 2520, 10.1161/01.CIR.96.8.2520
Abate, 1993, Variability in cholesterol content and physical properties of lipoproteins containing apolipoprotein B-100, Atherosclerosis, 104, 159, 10.1016/0021-9150(93)90187-Y
Vega, 1990, Does measurement of apolipoprotein B have a place in cholesterol management?, Arteriosclerosis, 10, 668, 10.1161/01.ATV.10.5.668
Havel, 1995, Management of primary hyperlipidemia, N Engl J Med, 332, 1491, 10.1056/NEJM199506013322207
Garg, 1990, Management of dyslipidemia in NIDDM, Diabetes Care, 13, 153, 10.2337/diacare.13.2.153
Vega, 1990, Does measurement of apolipoprotein B have a place in cholesterol management?, Arteriosclerosis, 10, 668, 10.1161/01.ATV.10.5.668
Sniderman, 1980, Association of coronary atherosclerosis with hyperapobetalipoproteinemia (increased protein but normal cholesterol levels in human plasma low density (B) lipoproteins), 77, 604
Brown, 1990, Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B, N Engl J Med, 323, 1289, 10.1056/NEJM199011083231901
Lamarche, 1995, Prevalence of dyslipidemic phenotypes in ischemic heart disease (prospective results from the Quebec cardiovascular study), Am J Cardiol, 75, 1189, 10.1016/S0002-9149(99)80760-7
Sniderman, 1997, To (measure apo) B or not to (measure apo) B: a critique of modern medical decision making, Clin Chem, 43, 1310, 10.1093/clinchem/43.8.1310
Ballantyne, 1998, Current thinking in lipid lowering, Am J Med, 104, 33S, 10.1016/S0002-9343(98)00186-7
Mahley, 1984, Plasma lipoproteins: apolipoprotein structure and function, J Lipid Res, 25, 1277, 10.1016/S0022-2275(20)34443-6
Puchois, 1987, Apolipoprotein A-I-containing lipoproteins in coronary artery disease, Atherosclerosis, 68, 35, 10.1016/0021-9150(87)90091-8
Fruchart, 1992, Apolipoprotein A-containing lipoprotein particles: physiologic role, quantification, and clinical significance, Clin Chem, 38, 793, 10.1093/clinchem/38.6.793
Krauss, 1992, Detection and quantitation of LDL subfractions, Curf Opin Lipidol, 3, 377, 10.1097/00041433-199212000-00005
Krauss, 1982, Identification of multiple subclasses of plasma low density lipoproteins in normal humans, J Lipid Res, 23, 97, 10.1016/S0022-2275(20)38178-5
Scheffer, 1997, Measurement of low-density lipoprotein particle size by high-performance gel-filtration chromatography, Clin Chem, 43, 1904, 10.1093/clinchem/43.10.1904
Scheffer, 1998, Measurement of LDL particle size in whole plasma and serum by high performance gel-filtration chromatography using a fluorescent lipid probe, Clin Chem, 44, 2148, 10.1093/clinchem/44.10.2148
Otvos, 1997, Measurement of lipoprotein subclass profiles by nuclear magnetic resonance spectroscopy, 497
Superko, 1997, The atherogenic lipoprotein profile, Science and Medicine, 4, 36
Superko, 1996, Lipid disorders contributing to coronary heart disease: an update, Curr Prob Cardiol, 21, 733, 10.1016/S0146-2806(96)80005-3
Hodis, 1995, Triglyceride-rich lipoproteins and the progression of coronary artery disease, Curr Opin Lipidol, 6, 209, 10.1097/00041433-199508000-00004
Havel, 1990, Role of triglyceride-rich lipoproteins in progression of atherosclerosis, Circulation, 82, 694, 10.1161/01.CIR.81.2.694
Hamsten, 1996, Triglycerides and coronary heart disease: has epidemiology given us the right answer?, 41
Karpe, 1995, Quantification of postprandial triglyceride-rich lipoproteins in healthy men by retinyl ester labeling and simultaneous measurement of apolipoproteins B-48 and B-100, Arterioscler Thromb Vasc Biol, 15, 199, 10.1161/01.ATV.15.2.199
Kugiyama, 1999, Remnant lipoprotein levels in fasting serum predict coronary events in patients with coronary artery disease, Circulation, 99, 2858, 10.1161/01.CIR.99.22.2858