Preventing Colitis-Associated Colon Cancer With Antioxidants: A Systematic Review
Tài liệu tham khảo
Frick, 2018, Overt increase of oxidative stress and DNA damage in murine and human colitis and colitis-associated neoplasia, Mol Cancer Res, 16, 634, 10.1158/1541-7786.MCR-17-0451
Nair, 2006, Increased etheno-DNA adducts in affected tissues of patients suffering from Crohn's disease, ulcerative colitis, and chronic pancreatitis, Antioxidants & Redox Signaling, 8, 1003, 10.1089/ars.2006.8.1003
Irrazabal, 2020, Limiting oxidative DNA damage reduces microbe-induced colitis-associated colorectal cancer, Nat Commun, 11, 1802, 10.1038/s41467-020-15549-6
Westbrook, 2009, Intestinal mucosal inflammation leads to systemic genotoxicity in mice, Cancer Res, 69, 4827, 10.1158/0008-5472.CAN-08-4416
Zhou, 2014, Reactive oxygen species in normal and tumor stem cells, Adv Cancer Res, 122, 1, 10.1016/B978-0-12-420117-0.00001-3
Panday, 2015, NADPH oxidases: an overview from structure to innate immunity-associated pathologies, Cellular & Molecular Immunology, 12, 5, 10.1038/cmi.2014.89
Mittal, 2014, Reactive oxygen species in inflammation and tissue injury, Antioxidants & Redox Signaling, 20, 1126, 10.1089/ars.2012.5149
Myant, 2013, ROS production and NF-kappaB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation, Cell Stem Cell, 12, 761, 10.1016/j.stem.2013.04.006
Coant, 2010, NADPH oxidase 1 modulates WNT and NOTCH1 signaling to control the fate of proliferative progenitor cells in the colon, Mol Cell Biol, 30, 2636, 10.1128/MCB.01194-09
Knaus, 2017, Pathogen control at the intestinal mucosa: H2O2 to the rescue, Gut Microbes, 8, 67, 10.1080/19490976.2017.1279378
Singh, 2018, Hydrogen peroxide production by lactobacilli promotes epithelial restitution during colitis, Redox Biology, 16, 11, 10.1016/j.redox.2018.02.003
Matthews, 2019, Proteomic analysis of microbial induced redox-dependent intestinal signaling, Redox Biology, 20, 526, 10.1016/j.redox.2018.11.011
Pisoschi, 2015, The role of antioxidants in the chemistry of oxidative stress: a review, Eur J Med Chem, 97, 55, 10.1016/j.ejmech.2015.04.040
Osburn, 2007, Increased colonic inflammatory injury and formation of aberrant crypt foci in Nrf2-deficient mice upon dextran sulfate treatment, Int J Cancer, 121, 1883, 10.1002/ijc.22943
Niles, 2006, Peroxynitrite-induced oxidation and nitration products of guanine and 8-oxoguanine: structures and mechanisms of product formation, Nitric Oxide, 14, 109, 10.1016/j.niox.2005.11.001
Ö, 2017, Myeloid cell-derived reactive oxygen species induce epithelial mutagenesis, Cancer Cell, 32, 869, 10.1016/j.ccell.2017.11.004
Kim, 2020, Glutathione S-transferase theta 1 protects against colitis through goblet cell differentiation via interleukin-22, FASEB J, 34, 3289, 10.1096/fj.201902421R
Visnes, 2018, Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation, Science, 362, 834, 10.1126/science.aar8048
Naik, 2011, Mitochondrial reactive oxygen species drive proinflammatory cytokine production, J Exp Med, 208, 417, 10.1084/jem.20110367
Zhou, 2011, A role for mitochondria in NLRP3 inflammasome activation, Nature, 469, 221, 10.1038/nature09663
Bulua, 2011, Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS), J Exp Med, 208, 519, 10.1084/jem.20102049
Formentini, 2017, Mitochondrial ROS production protects the intestine from inflammation through functional M2 macrophage polarization, Cell Rep, 19, 1202, 10.1016/j.celrep.2017.04.036
Gulhane, 2016, High fat diets induce colonic epithelial cell stress and inflammation that is reversed by IL-22, Sci Rep, 6, 28990, 10.1038/srep28990
Cremonini, 2019, Anthocyanins protect the gastrointestinal tract from high fat diet-induced alterations in redox signaling, barrier integrity and dysbiosis, Redox Biology, 26, 101269, 10.1016/j.redox.2019.101269
Biedermann, 2013, Bilberry ingestion improves disease activity in mild to moderate ulcerative colitis: an open pilot study, J Crohns Colitis, 7, 271, 10.1016/j.crohns.2012.07.010
Hou, 2011, Dietary intake and risk of developing inflammatory bowel disease: a systematic review of the literature, Am J Gastroenterol, 106, 563, 10.1038/ajg.2011.44
Zhong, 2016, NF-κB restricts inflammasome activation via elimination of damaged mitochondria, Cell, 164, 896, 10.1016/j.cell.2015.12.057
Brown, 2003, The mismatch repair system is required for S-phase checkpoint activation, Nat Genet, 33, 80, 10.1038/ng1052
Markkanen, 2017, Not breathing is not an option: how to deal with oxidative DNA damage, DNA Repair, 59, 82, 10.1016/j.dnarep.2017.09.007
Colussi, 2002, The mammalian mismatch repair pathway removes DNA 8-oxodGMP incorporated from the oxidized dNTP pool, Curr Biol, 12, 912, 10.1016/S0960-9822(02)00863-1
Russo, 2007, Different DNA repair strategies to combat the threat from 8-oxoguanine, Mutat Res, 614, 69, 10.1016/j.mrfmmm.2006.03.007
Beltran, 2010, Mitochondrial dysfunction, persistent oxidative damage, and catalase inhibition in immune cells of naive and treated Crohn's disease, Inflamm Bowel Dis, 16, 76, 10.1002/ibd.21027
Chang, 2012, Association of catalase genotype with oxidative stress in the predication of colorectal cancer: modification by epidemiological factors, Biomed Environ Sci, 25, 156
Horie, 2018, Peroxiredoxin 1 expression in active ulcerative colitis mucosa identified by proteome analysis and involvement of thioredoxin based on immunohistochemistry, Oncology Letters, 15, 2364
Fischer, 2018, Peroxiredoxins in colorectal cancer: predictive biomarkers of radiation response and therapeutic targets to increase radiation sensitivity?, Antioxidants, 7, 10.3390/antiox7100136
Peng, 2017, Peroxiredoxin 2 is associated with colorectal cancer progression and poor survival of patients, Oncotarget, 8, 15057, 10.18632/oncotarget.14801
Huang, 2018, Expression of PRDX6 correlates with migration and invasiveness of colorectal cancer cells, Cell Physiol Biochem, 51, 2616, 10.1159/000495934
Jia, 2019, The role of thioredoxin system in cancer: strategy for cancer therapy, Cancer Chemother Pharmacol, 84, 453, 10.1007/s00280-019-03869-4
Barrett, 2017, Selenoproteins and oxidative stress-induced inflammatory tumorigenesis in the gut, Cell Mol Life Sci, 74, 607, 10.1007/s00018-016-2339-2
Te Velde, 2008, Glutathione peroxidase 2 and aquaporin 8 as new markers for colonic inflammation in experimental colitis and inflammatory bowel diseases: an important role for H2O2?, Eur J Gastroenterol Hepatol, 20, 555, 10.1097/MEG.0b013e3282f45751
Meplan, 2010, Genetic variants in selenoprotein genes increase risk of colorectal cancer, Carcinogenesis, 31, 1074, 10.1093/carcin/bgq076
Barrett, 2013, Tumor suppressor function of the plasma glutathione peroxidase gpx3 in colitis-associated carcinoma, Cancer Res, 73, 1245, 10.1158/0008-5472.CAN-12-3150
Steven Esworthy, 2013, The Gdac1 locus modifies spontaneous and Salmonella-induced colitis in mice deficient in either Gpx2 or Gpx1 gene, Free Radic Biol Med, 65, 1273, 10.1016/j.freeradbiomed.2013.09.013
Florian, 2010, Loss of GPx2 increases apoptosis, mitosis, and GPx1 expression in the intestine of mice, Free Radic Biol Med, 49, 1694, 10.1016/j.freeradbiomed.2010.08.029
Esworthy, 2001, Mice with combined disruption of Gpx1 and Gpx2 genes have colitis, Am J Physiol Gastrointest Liver Physiol, 281, G848, 10.1152/ajpgi.2001.281.3.G848
Chu, 2017, Deficiency in Duox2 activity alleviates ileitis in GPx1- and GPx2-knockout mice without affecting apoptosis incidence in the crypt epithelium, Redox Biology, 11, 144, 10.1016/j.redox.2016.11.001
Esworthy, 2014, Nox1 causes ileocolitis in mice deficient in glutathione peroxidase-1 and -2, Free Radic Biol Med, 68, 315, 10.1016/j.freeradbiomed.2013.12.018
Perkins, 2015, Peroxiredoxins: guardians against oxidative stress and modulators of peroxide signaling, Trends Biochem Sci, 40, 435, 10.1016/j.tibs.2015.05.001
Lu, 2014, Peroxiredoxin 2 is upregulated in colorectal cancer and contributes to colorectal cancer cells' survival by protecting cells from oxidative stress, Mol Cell Biochem, 387, 261, 10.1007/s11010-013-1891-4
Nicolussi, 2017, The role of peroxiredoxins in cancer, Molecular and Clinical Oncology, 6, 139, 10.3892/mco.2017.1129
Takagi, 2019, Elevated ER stress exacerbates dextran sulfate sodium-induced colitis in PRDX4-knockout mice, Free Radic Biol Med, 134, 153, 10.1016/j.freeradbiomed.2018.12.024
Sido, 1998, Impairment of intestinal glutathione synthesis in patients with inflammatory bowel disease, Gut, 42, 485, 10.1136/gut.42.4.485
Clapper, 1998, Glutathione S-transferases: biomarkers of cancer risk and chemopreventive response, Chem Biol Interact, 111–112, 377, 10.1016/S0009-2797(97)00174-9
Zhang, 2020, Efficacy of serum total bilirubin in predicting the severity of ulcerative colitis: a cross-sectional study, Ann Clin Lab Sci, 50, 228
Su, 2019, Low serum bilirubin, albumin, and uric acid levels in patients with Crohn's disease, Medicine, 98, 10.1097/MD.0000000000015664
Terry, 2009, Melatonin and ulcerative colitis: evidence, biological mechanisms, and future research, Inflamm Bowel Dis, 15, 134, 10.1002/ibd.20527
Ishihara, 2009, Therapeutic effect of lecithinized superoxide dismutase against colitis, J Pharmacol Exp Ther, 328, 152, 10.1124/jpet.108.144451
Suzuki, 2008, A lecithinized superoxide dismutase (PC-SOD) improves ulcerative colitis, Colorectal Dis, 10, 931, 10.1111/j.1463-1318.2008.01487.x
Hou, 2014, Superoxide dismutase recombinant Lactobacillus fermentum ameliorates intestinal oxidative stress through inhibiting NF-kappaB activation in a trinitrobenzene sulphonic acid-induced colitis mouse model, J Appl Microbiol, 116, 1621, 10.1111/jam.12461
Sheng, 2019, A manganese-superoxide dismutase from Thermus thermophilus HB27 suppresses inflammatory responses and alleviates experimentally induced colitis, Inflamm Bowel Dis, 25, 1644, 10.1093/ibd/izz097
LeBlanc, 2011, Use of superoxide dismutase and catalase producing lactic acid bacteria in TNBS induced Crohn's disease in mice, Journal of Biotechnology, 151, 287, 10.1016/j.jbiotec.2010.11.008
Del Carmen, 2014, Genetically engineered immunomodulatory Streptococcus thermophilus strains producing antioxidant enzymes exhibit enhanced anti-inflammatory activities, Appl Environ Microbiol, 80, 869, 10.1128/AEM.03296-13
Tamaki, 2006, Human thioredoxin-1 ameliorates experimental murine colitis in association with suppressed macrophage inhibitory factor production, Gastroenterology, 131, 1110, 10.1053/j.gastro.2006.08.023
Hirota, 1999, Distinct roles of thioredoxin in the cytoplasm and in the nucleus: a two-step mechanism of redox regulation of transcription factor NF-kappaB, J Biol Chem, 274, 27891, 10.1074/jbc.274.39.27891
Ardite, 2000, Replenishment of glutathione levels improves mucosal function in experimental acute colitis, Lab Invest, 80, 735, 10.1038/labinvest.3780077
El-Gowelli, 2015, Co-administration of alpha-lipoic acid and cyclosporine aggravates colon ulceration of acetic acid-induced ulcerative colitis via facilitation of NO/COX-2/miR-210 cascade, Toxicol Appl Pharmacol, 288, 300, 10.1016/j.taap.2015.08.002
Moura, 2016, Colonic and hepatic modulation by lipoic acid and/or N-acetylcysteine supplementation in mild ulcerative colitis induced by dextran sodium sulfate in rats, Oxidative Medicine and Cellular Longevity, 2016, 4047362, 10.1155/2016/4047362
Mirza-Aghazadeh-Attari, 2020, Melatonin: an important anticancer agent in colorectal cancer, J Cell Physiol, 235, 804, 10.1002/jcp.29049
Tahan, 2011, Melatonin expresses powerful anti-inflammatory and antioxidant activities resulting in complete improvement of acetic-acid-induced colitis in rats, Dig Dis Sci, 56, 715, 10.1007/s10620-010-1364-5
Iravani, 2019, The role of melatonin in colorectal cancer, Journal of Gastrointestinal Cancer
Chojnacki, 2013, Evaluation of enterochromaffin cells and melatonin secretion exponents in ulcerative colitis, World J Gastroenterol, 19, 3602, 10.3748/wjg.v19.i23.3602
Trivedi, 2013, Melatonin reduces ulcerative colitis-associated local and systemic damage in mice: investigation on possible mechanisms, Dig Dis Sci, 58, 3460, 10.1007/s10620-013-2831-6
Myung, 2010, Effects of antioxidant supplements on cancer prevention: meta-analysis of randomized controlled trials, Ann Oncol, 21, 166, 10.1093/annonc/mdp286
Gill, 2016, Cancer, oxidative stress, and metastasis, Cold Spring Harb Symp Quant Biol, 81, 163, 10.1101/sqb.2016.81.030791
Bjelakovic, 2007, Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis, JAMA, 297, 842, 10.1001/jama.297.8.842
Kohan, 2020, Reactive oxygen species in cancer: a paradox between pro- and anti-tumour activities, Cancer Chemother Pharmacol, 86, 1, 10.1007/s00280-020-04103-2
Zhang, 2010, A systems biology perspective on Nrf2-mediated antioxidant response, Toxicol Appl Pharmacol, 244, 84, 10.1016/j.taap.2009.08.018
Sayin, 2014, Antioxidants accelerate lung cancer progression in mice, Science Translational Medicine, 6, 221ra15, 10.1126/scitranslmed.3007653
Piskounova, 2015, Oxidative stress inhibits distant metastasis by human melanoma cells, Nature, 527, 186, 10.1038/nature15726
Le Gal, 2015, Antioxidants can increase melanoma metastasis in mice, Science Translational Medicine, 7, 308re8, 10.1126/scitranslmed.aad3740
Saber, 2019, Telmisartan ameliorates dextran sodium sulfate-induced colitis in rats by modulating NF-kappaB signalling in the context of PPARgamma agonistic activity, Arch Biochem Biophys, 671, 185, 10.1016/j.abb.2019.07.014
Peppas, 2020, Statins and inflammatory bowel disease: where do we stand?, European Journal of Internal Medicine, 75, 10, 10.1016/j.ejim.2020.02.017
Maheshwari, 2015, Protective effect of simvastatin and rosuvastatin on trinitrobenzene sulfonic acid-induced colitis in rats, Indian Journal of Pharmacology, 47, 17, 10.4103/0253-7613.150311
Wang, 2013, Protective effects of N-acetylcysteine on acetic acid-induced colitis in a porcine model, BMC Gastroenterology, 13, 133, 10.1186/1471-230X-13-133
Uraz, 2013, N-acetylcysteine expresses powerful anti-inflammatory and antioxidant activities resulting in complete improvement of acetic acid-induced colitis in rats, Scand J Clin Lab Invest, 73, 61, 10.3109/00365513.2012.734859
Kurutas, 2005, Effects of antioxidant therapy on leukocyte myeloperoxidase and Cu/Zn-superoxide dismutase and plasma malondialdehyde levels in experimental colitis, Mediators of Inflammation, 2005, 390, 10.1155/MI.2005.390
Guijarro, 2008, N-acetyl-L-cysteine combined with mesalamine in the treatment of ulcerative colitis: randomized, placebo-controlled pilot study, World J Gastroenterol, 14, 2851, 10.3748/wjg.14.2851
Merra, 2012, Propionyl-L-carnitine hydrochloride for treatment of mild to moderate colonic inflammatory bowel diseases, World J Gastroenterol, 18, 5065, 10.3748/wjg.v18.i36.5065
Mikhailova, 2011, Randomised clinical trial: the efficacy and safety of propionyl-L-carnitine therapy in patients with ulcerative colitis receiving stable oral treatment, Aliment Pharmacol Ther, 34, 1088, 10.1111/j.1365-2036.2011.04844.x
Masri, 2015, Role of vitamins in gastrointestinal diseases, World J Gastroenterol, 21, 5191, 10.3748/wjg.v21.i17.5191
Tahan, 2011, Vitamin E has a dual effect of anti-inflammatory and antioxidant activities in acetic acid-induced ulcerative colitis in rats, Can J Surg, 54, 333, 10.1503/cjs.013610
Mirbagheri, 2008, Rectal administration of d-alpha tocopherol for active ulcerative colitis: a preliminary report, World J Gastroenterol, 14, 5990, 10.3748/wjg.14.5990
Aghdassi, 2003, Antioxidant vitamin supplementation in Crohn's disease decreases oxidative stress. a randomized controlled trial, Am J Gastroenterol, 98, 348
Kondo, 2019, Ameliorative effect of high-dose vitamin C administration on dextran sulfate sodium-induced colitis mouse model, Biol Pharm Bull, 42, 954, 10.1248/bpb.b18-00967
Yan, 2015, Ascorbic acid ameliorates oxidative stress and inflammation in dextran sulfate sodium-induced ulcerative colitis in mice, International Journal of Clinical and Experimental Medicine, 8, 20245
Sakamoto, 2005, Epidemiology Group of the Research Committee on Inflammatory Bowel Disease in Japan. Dietary risk factors for inflammatory bowel disease: a multicenter case-control study in Japan, Inflamm Bowel Dis, 11, 154, 10.1097/00054725-200502000-00009
Seril, 2002, Inhibition of chronic ulcerative colitis-associated colorectal adenocarcinoma development in a murine model by N-acetylcysteine, Carcinogenesis, 23, 993, 10.1093/carcin/23.6.993
Amrouche-Mekkioui, 2012, N-acetylcysteine improves redox status, mitochondrial dysfunction, mucin-depleted crypts and epithelial hyperplasia in dextran sulfate sodium-induced oxidative colitis in mice, Eur J Pharmacol, 691, 209, 10.1016/j.ejphar.2012.06.014
Rao, 2002, Chemopreventive properties of a selective inducible nitric oxide synthase inhibitor in colon carcinogenesis, administered alone or in combination with celecoxib, a selective cyclooxygenase-2 inhibitor, Cancer Res, 62, 165
Zhao, 2017, Small molecule GL-V9 protects against colitis-associated colorectal cancer by limiting NLRP3 inflammasome through autophagy, Oncoimmunology, 7
Ananthakrishnan, 2016, Statin use is associated with reduced risk of colorectal cancer in patients with inflammatory bowel diseases, Clin Gastroenterol Hepatol, 14, 973, 10.1016/j.cgh.2016.02.017
Mak, 2020, Cancer risk and chemoprevention in Chinese inflammatory bowel disease patients: a population-based cohort study, Scand J Gastroenterol, 55, 279, 10.1080/00365521.2020.1731760
Lutsenko, 2002, Vitamin C prevents DNA mutation induced by oxidative stress, J Biol Chem, 277, 16895, 10.1074/jbc.M201151200
Kazmierczak-Baranska, 2020, Two faces of vitamin C: antioxidative and pro-oxidative agent, Nutrients, 12, 10.3390/nu12051501
Chen, 2005, Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues, Proc Natl Acad Sci U S A, 102, 13604, 10.1073/pnas.0506390102
El Halabi, 2018, Ascorbic acid in colon cancer: from the basic to the clinical applications, International Journal of Molecular Sciences, 19, 10.3390/ijms19092752
McFadden, 2015, The role of curcumin in modulating colonic microbiota during colitis and colon cancer prevention, Inflamm Bowel Dis, 21, 2483, 10.1097/MIB.0000000000000522
Marjaneh, 2018, Phytosomal curcumin inhibits tumor growth in colitis-associated colorectal cancer, J Cell Physiol, 233, 6785, 10.1002/jcp.26538
Cui, 2010, Resveratrol suppresses colitis and colon cancer associated with colitis, Cancer Prevention Research, 3, 549, 10.1158/1940-6207.CAPR-09-0117
Wang, 2020, Resveratrol attenuates inflammatory bowel disease in mice by regulating SUMO1, Biol Pharm Bull, 43, 450, 10.1248/bpb.b19-00786
Bjelakovic, 2004, Antioxidant supplements for prevention of gastrointestinal cancers: a systematic review and meta-analysis, Lancet, 364, 1219, 10.1016/S0140-6736(04)17138-9
Bussey, 1982, A randomized trial of ascorbic acid in polyposis coli, Cancer, 50, 1434, 10.1002/1097-0142(19821001)50:7<1434::AID-CNCR2820500733>3.0.CO;2-F
Forman, 2004, Vitamins to prevent cancer: supplementary problems, Lancet, 364, 1193, 10.1016/S0140-6736(04)17153-5
Greenberg, 1994, A clinical trial of antioxidant vitamins to prevent colorectal adenoma: Polyp Prevention Study Group, N Engl J Med, 331, 141, 10.1056/NEJM199407213310301
Diakowska, 2007, Oxidative DNA damage and total antioxidant status in serum of patients with esophageal squamous cell carcinoma, Hepatogastroenterology, 54, 1701
Alexandrov, 2020, The repertoire of mutational signatures in human cancer, Nature, 578, 94, 10.1038/s41586-020-1943-3
Diao, 2016, Vitamin E promotes breast cancer cell proliferation by reducing ROS production and p53 expression, Eur Rev Med Pharmacol Sci, 20, 2710
Markowitz, 2009, Molecular origins of cancer: molecular basis of colorectal cancer, N Engl J Med, 361, 2449, 10.1056/NEJMra0804588
Beaugerie, 2015, Cancers complicating inflammatory bowel disease, N Engl J Med, 372, 1441, 10.1056/NEJMra1403718
Chen, 2016, The cell-cycle arrest and apoptotic functions of p53 in tumor initiation and progression, Cold Spring Harbor Perspectives in Medicine, 6, a026104, 10.1101/cshperspect.a026104
Sablina, 2005, The antioxidant function of the p53 tumor suppressor, Nat Med, 11, 1306, 10.1038/nm1320
Lang, 2013, Mutation rates, spectra, and genome-wide distribution of spontaneous mutations in mismatch repair deficient yeast, G3 (Bethesda), 3, 1453, 10.1534/g3.113.006429
Denson, 2018, Clinical and genomic correlates of neutrophil reactive oxygen species production in pediatric patients with Crohn's disease, Gastroenterology, 154, 2097, 10.1053/j.gastro.2018.02.016
Dhillon, 2014, Variants in nicotinamide adenine dinucleotide phosphate oxidase complex components determine susceptibility to very early onset inflammatory bowel disease, Gastroenterology, 147, 680, 10.1053/j.gastro.2014.06.005
Hayes, 2015, Defects in NADPH oxidase genes NOX1 and DUOX2 in very early onset inflammatory bowel disease, Cell Mol Gastroenterol Hepatol, 1, 489, 10.1016/j.jcmgh.2015.06.005
Parlato, 2017, First identification of biallelic inherited DUOX2 inactivating mutations as a cause of very early onset inflammatory bowel disease, Gastroenterology, 153, 609, 10.1053/j.gastro.2016.12.053
Huang, 2016, Genetic risk for inflammatory bowel disease is a determinant of Crohn's disease development in chronic granulomatous disease, Inflamm Bowel Dis, 22, 2794, 10.1097/MIB.0000000000000966
Angelino, 2017, Inflammatory bowel disease in chronic granulomatous disease: an emerging problem over a twenty years' experience, Pediatr Allergy Immunol, 28, 801, 10.1111/pai.12814
Masnadi Shirazi, 2018, Vitamin A supplementation decreases disease activity index in patients with ulcerative colitis: a randomized controlled clinical trial, Complement Ther Med, 41, 215, 10.1016/j.ctim.2018.09.026
Hanai, 2006, Curcumin maintenance therapy for ulcerative colitis: randomized, multicenter, double-blind, placebo-controlled trial, Clin Gastroenterol Hepatol, 4, 1502, 10.1016/j.cgh.2006.08.008
Sadeghi, 2020, The effect of curcumin supplementation on clinical outcomes and inflammatory markers in patients with ulcerative colitis, Phytother Res, 34, 1123, 10.1002/ptr.6581
Masoodi, 2018, The efficacy of curcuminoids in improvement of ulcerative colitis symptoms and patients' self-reported well-being: a randomized double-blind controlled trial, J Cell Biochem, 119, 9552, 10.1002/jcb.27273
Lang, 2015, Curcumin in combination with mesalamine induces remission in patients with mild-to-moderate ulcerative colitis in a randomized controlled trial, Clin Gastroenterol Hepatol, 13, 1444, 10.1016/j.cgh.2015.02.019
Singla, 2014, Induction with NCB-02 (curcumin) enema for mild-to-moderate distal ulcerative colitis: a randomized, placebo-controlled, pilot study, J Crohns Colitis, 8, 208, 10.1016/j.crohns.2013.08.006
Sugimoto, 2020, Highly bioavailable curcumin derivative ameliorates Crohn's disease symptoms: a randomized, double-blind, multicenter study, J Crohns Colitis, 10.1093/ecco-jcc/jjaa097
Samsamikor, 2016, Resveratrol supplementation and oxidative/anti-oxidative status in patients with ulcerative colitis: a randomized, double-blind, placebo-controlled pilot study, Arch Med Res, 47, 304, 10.1016/j.arcmed.2016.07.003
Samsami-Kor, 2015, Anti-inflammatory effects of resveratrol in patients with ulcerative colitis: a randomized, double-blind, placebo-controlled pilot study, Arch Med Res, 46, 280, 10.1016/j.arcmed.2015.05.005
Albanes, 2000, Effects of supplemental alpha-tocopherol and beta-carotene on colorectal cancer: results from a controlled trial (Finland), Cancer Causes Control, 11, 197, 10.1023/A:1008936214087
Malila, 1999, The effect of alpha-tocopherol and beta-carotene supplementation on colorectal adenomas in middle-aged male smokers, Cancer Epidemiol Biomarkers Prev, 8, 489
Hofstad, 1998, Growth and recurrence of colorectal polyps: a double-blind 3-year intervention with calcium and antioxidants, Digestion, 59, 148, 10.1159/000007480
Hopkins, 2010, Antioxidant micronutrients and biomarkers of oxidative stress and inflammation in colorectal adenoma patients: results from a randomized, controlled clinical trial, Cancer Epidemiol Biomarkers Prev, 19, 850, 10.1158/1055-9965.EPI-09-1052
Roncucci, 1993, Antioxidant vitamins or lactulose for the prevention of the recurrence of colorectal adenomas: Colorectal Cancer Study Group of the University of Modena and the Health Care District 16, Dis Colon Rectum, 36, 227, 10.1007/BF02053502
McKeown-Eyssen, 1988, A randomized trial of vitamins C and E in the prevention of recurrence of colorectal polyps, Cancer Res, 48, 4701
Moertel, 1985, High-dose vitamin C versus placebo in the treatment of patients with advanced cancer who have had no prior chemotherapy: a randomized double-blind comparison, N Engl J Med, 312, 137, 10.1056/NEJM198501173120301
Cameron, 1976, Supplemental ascorbate in the supportive treatment of cancer: prolongation of survival times in terminal human cancer, Proc Natl Acad Sci U S A, 73, 3685, 10.1073/pnas.73.10.3685
Wang, 2019, Phase I study of high-dose ascorbic acid with mFOLFOX6 or FOLFIRI in patients with metastatic colorectal cancer or gastric cancer, BMC Cancer, 19, 460, 10.1186/s12885-019-5696-z
Lance, 2017, Colorectal adenomas in participants of the SELECT randomized trial of selenium and vitamin E for prostate cancer prevention, Cancer Prevention Research, 10, 45, 10.1158/1940-6207.CAPR-16-0104
Thompson, 2016, Selenium supplementation for prevention of colorectal adenomas and risk of associated type 2 diabetes, J Natl Cancer Inst, 108, 10.1093/jnci/djw152
Reid, 2006, Selenium supplementation and colorectal adenomas: an analysis of the nutritional prevention of cancer trial, Int J Cancer, 118, 1777, 10.1002/ijc.21529
Bonelli, 2013, Antioxidant supplement and long-term reduction of recurrent adenomas of the large bowel: a double-blind randomized trial, J Gastroenterol, 48, 698, 10.1007/s00535-012-0691-z
Ribeiro, 2016, Effect of zinc supplementation on antioxidant defenses and oxidative stress markers in patients undergoing chemotherapy for colorectal cancer: a placebo-controlled, prospective randomized trial, Biol Trace Elem Res, 169, 8, 10.1007/s12011-015-0396-2
Cruz-Correa, 2018, Efficacy and safety of curcumin in treatment of intestinal adenomas in patients with familial adenomatous polyposis, Gastroenterology, 155, 668, 10.1053/j.gastro.2018.05.031
Howells, 2019, Curcumin combined with FOLFOX chemotherapy is safe and tolerable in patients with metastatic colorectal cancer in a randomized phase IIa trial, J Nutr, 149, 1133
Shin, 2018, Green tea extracts for the prevention of metachronous colorectal polyps among patients who underwent endoscopic removal of colorectal adenomas: a randomized clinical trial, Clin Nutr, 37, 452, 10.1016/j.clnu.2017.01.014
Shimizu, 2008, Green tea extracts for the prevention of metachronous colorectal adenomas: a pilot study, Cancer Epidemiol Biomarkers Prev, 17, 3020, 10.1158/1055-9965.EPI-08-0528
Hoensch, 2008, Prospective cohort comparison of flavonoid treatment in patients with resected colorectal cancer to prevent recurrence, World J Gastroenterol, 14, 2187, 10.3748/wjg.14.2187
Estensen, 1999, N-acetylcysteine suppression of the proliferative index in the colon of patients with previous adenomatous colonic polyps, Cancer Lett, 147, 109, 10.1016/S0304-3835(99)00281-5
Kuyumcu, 2015, Improved oxidative status in major abdominal surgery patients after N-acetyl cystein supplementation, Nutrition Journal, 14, 4, 10.1186/1475-2891-14-4