Prevalence of Chronic Kidney Disease among the High Risk Population in South-Western Ghana; A Cross Sectional Study

Richard K.D. Ephraim1, Sylvester Biekpe1, Samuel Asamoah Sakyi2,3, Prince Adoba1, Hope Agbodjakey1, Enoch O. Antoh2
1Department of Medical Laboratory Technology, School of Allied Health Sciences, University of Cape Coast, Cape Coast, Ghana
2Department of Molecular Medicine, School of Medical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana
3Noguchi Memorial Institute for Medical Research, Legon, Ghana

Tóm tắt

Background: Chronic Kidney Disease (CKD) is a major global health problem. CKD is one of the most common complications of diabetes mellitus and hypertension and carries a risk of cardiovascular morbidity and mortality and progression to end-stage kidney disease. Objectives: This study sought to use the 2012 Kidney Disease Improving Global Outcomes (KDIGO) definitions to establish the prevalence and risk factors for CKD among a high risk population in the Sekondi-Takoradi metropolis. Design: Cross sectional study. Setting: Effia-Nkwanta regional and the Takoradi Government hospitals in South Western Ghana. Patients: Two hundred eight consecutive adults with diabetes, hypertension or both. Measurements: Serum creatinine and urine albumin-creatinine ratio respectively. The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) was used to estimate glomerular filtration rate (GFR). Methods: CKD was classified according to KDIGO. Results: The prevalence of CKD was 30 %: 27 % in patients with diabetes, 22 % in patients with hypertension only and 74 % in patients with both diabetes and hypertension. GFR category G3a CKD was most prevalent stage (9 %). Albuminuria was highest among people with diabetes (39 %). Limitations: A convenience sample of patients attending clinics. Conclusion: CKD was prevalent in these high-risk patients.

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