Presynaptic Endosomal Cathepsin D Regulates the Biogenesis of GABAergic Synaptic Vesicles

Cell Reports - Tập 28 - Trang 1015-1028.e5 - 2019
Xia Li1,2, Liming Qin1, Yefei Li1, Hao Yu1,3, Zhijun Zhang4, Changlu Tao5, Yijun Liu1, Yanhong Xue6, Xiaoxing Zhang1, Zhenghao Xu1, Yi Wang1, Huifang Lou1, Zhibin Tan1, Paul Saftig7, Zhong Chen1, Tao Xu6, Guoqiang Bi5, Shumin Duan1, Zhihua Gao1
1Department of Neurobiology and Department of Neurology of Second Affiliated Hospital, NHC and CAMS Key Laboratory of Medical Neurobiology, Key Laboratory of Medical Neurobiology of Zhejiang Province, Zhejiang University School of Medicine, Hangzhou 310058, China
2Institute of Nautical Medicine, Academy of Special Environmental Medicine, Nantong University, Nantong 226001, China
3Department of Neurology and Research Center of Neurology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China
4Med-X Research Institute and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China
5School of Life Science, University of Science and Technology of China, Hefei 230026, China
6Institute of Biophysics, Chinese Academy of Science, Beijing 100101, China
7Institute of Biochemistry, University of Kiel, Kiel 24118, Germany

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