Preparation and partial characterization of monoclonal antibodies specific for the nascent non-triple helical form of the type IV collagen alpha 1 chain

Kühn, 1995, Basement membrane (type IV) collagen, Matrix Biol., 14, 439, 10.1016/0945-053X(95)90001-2 Brinckmann, 2005, Current Chemistry: 247 Quail, 2013, Microenvironmental regulation of tumor progression and metastasis, Nat. Med., 19, 1423, 10.1038/nm.3394 Xu, 2001, Proteolytic exposure of a cryptic site within collagen type IV is required for angiogenesis and tumor growth in vivo, J. Cell Biol., 154, 1069, 10.1083/jcb.200103111 Colorado, 2000, Anti-angiogenic cues from vascular basement membrane collagen, Cancer Res., 60, 2520 Mundel, 2007, Type IV collagen-derived angiogenesis inhibitors, Micro. Res., 74, 85, 10.1016/j.mvr.2007.05.005 Takahashi, 1999, Serum-dependent Secretion of Nondisulfide-bonded and Unfolded Type IV Collagen α Chains by Cultured Fetal Lung Fibroblasts, Connect. Tissue, 31, 161 Kajimura, 2004, Non-helical type IV collagen polypeptides in human placenta, Biochem Biophys. Res Commun., 314, 11, 10.1016/j.bbrc.2003.12.061 Yoshikawa, 2001, Secretion of non-helical collagenous polypeptides of alpha1(IV) and alpha2(IV) chains upon depletion of ascorbate by cultured human cells, J. Biochem., 129, 929, 10.1093/oxfordjournals.jbchem.a002939 Uitto, 1972, Failure of the intracellular collagen to assume a triple-helical conformation, Biochim. Biophys. Acta, 278, 601, 10.1016/0005-2795(72)90023-2 Steinmann, 1981, Intracellular degradation of newly synthesized collagen is conformation-dependent, FEBS Lett., 133, 142, 10.1016/0014-5793(81)80491-7 Sasaki, 1987, Reduction of collagen production in keloid fibroblast cultures by ethyl-3,4-dihydroxybenzoate. Inhibition of prolyl hydroxylase activity as a mechanism of action, J Biol. Chem., 262, 9397, 10.1016/S0021-9258(18)48093-3 Sugiyama, 2015, Non-triple helical form of type IV collagen α1 chain, Heliyon, 1, e00051, 10.1016/j.heliyon.2015.e00051 Kino, 1991, A novel chain of basement membrane-associated collagen as revealed by biochemical and immunohistochemical characterizations of the epitope recognized by a monoclonal antibody against human placenta basement membrane collagen, Am. J. Pathol., 138, 911 Iwata, 1995, Evidence for a short form of alpha 1(IV) as a major polypeptide in bovine lens capsule, J. Biochem., 117, 1298, 10.1093/oxfordjournals.jbchem.a124858 Muraoka, 1993, Three polypeptides with distinct biochemical properties are major alpha chain-size components of type IV collagen in bovine lens capsule, J. Biochem., 114, 358, 10.1093/oxfordjournals.jbchem.a124181 Iwata, 1996, The 160k alpha 1(IV) chain, a short form of a type IV collagen polypeptide, of bovine lens capsule retains the NC1 domain, J. Biochem., 120, 133, 10.1093/oxfordjournals.jbchem.a021374 Laemmli, 1970, Cleavage of structural proteins during the assembly of the head of bacteriophage T4, Nature, 227, 680, 10.1038/227680a0 Crouch, 1980, Structural basis for apparent heterogeneity of collagens in human basement membranes: type IV procollagen contains two distinct chains, Proc. Natl. Acad. Sci. Usa., 77, 745, 10.1073/pnas.77.2.745 Timpl, 1981, A network model for the organization of type IV collagen molecules in basement membranes, Eur. J. Biochem., 120, 203, 10.1111/j.1432-1033.1981.tb05690.x George, 1999, Elevated serum type IV collagen: a sensitive indicator of the presence of cirrhosis in haemochromatosis, J. Hepatol., 31, 47, 10.1016/S0168-8278(99)80162-7