Preparation and In Vivo Evaluation of a Water-Soluble Prodrug for 2R-γ-Tocotrienol and as a Two-Step Prodrug for 2,7,8-Trimethyl-2S-(β-carboxyethyl)-6-hydroxychroman (S-γ-CEHC) in Rat

Drug Metabolism and Disposition - Tập 35 Số 9 - Trang 1502-1510 - 2007
Nami Akaho1, Jiro Takata2, Takeshi Fukushima3, Kazuhisa Matsunaga2, Akihiro Hattori4, Ryoji Hidaka2, Kosuke Fukui2, Miyako Yoshida2, Toshihiro Fujioka2, Yoshiharu Karube2, Kazuhiro Imai5
1Faculty of Pharmaceutical Sciences, Fukuoka University, Nanakuma, Johnan-ku, Fukuoka 814-0180, Japan
2Fukuoka University
3The University of Tokyo; University of Shizuoka
4The University of Tokyo,
5Musashino University; The University of Tokyo

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