Preoperative Neutrophil–Lymphocyte Ratio and Saphenous Vein Graft Patency After Coronary Artery Bypass Grafting

Clinical and Applied Thrombosis/Hemostasis - Tập 20 Số 8 - Trang 819-824 - 2014
İrfan Taşoğlu1, Osman Turak2, Yunus Nazlı3, Fırat Özcan2, Necmettin Çolak3, Serpil ŞAHİN1, Kemal Kavasoğlu1, Bahadır Genc1, Doğan Emre Sert1, Mehmet Karahan1, Ömer Faruk Çiçek1, Ata Niyazi Ecevit1
1Department of Cardiovascular Surgery, Turkiye Yuksek Ihtisas Heart Education and Research Hospital, Ankara, Turkey.
2Department of Cardiology, Turkiye Yuksek Ihtisas Heart, Education and Research Hospital, Ankara, Turkey.
3Department of Cardiovascular Surgery, Fatih Unıversty Medical Faculty, Ankara, Turkey

Tóm tắt

Aim: The aim of the present study was to investigate the predictive value of preoperative neutrophil–lymphocyte ratio (NLR) in postoperative saphenous vein graft patency in patients undergoing coronary artery bypass grafting (CABG) surgery. Method: We retrospectively analyzed 444 patients who had undergone CABG and a further control coronary angiography due to recurrence of symptoms. The patients were divided into tertile groups according to the NLR. The primary end point was 50% saphenous vein graft stenosis or more or complete occlusion. Result: The saphenous vein graft failure in the 3 groups based on NLR was 33%, 66.2%, and 79.1%, in the low-, middle- and high-risk groups, respectively. In multivariate regression modeling, current smoker, diabetes mellitus, target artery diameter <1.5 mm, and NLR independently predicted saphenous vein graft patency in patients after CABG. Conclusion: Preoperative NLR is clearly an independent predictor of saphenous vein graft patency in patients after CABG.

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