Premotor and nonmotor features of Parkinson's disease

Berg, 2014, Time to redefine PD Introductory statement of the MDS Task Force on the definition of Parkinsons disease., Mov Disord, 29, 454, 10.1002/mds.25844

Siderowf, 2012, Premotor Parkinsons disease: concepts and definitions., Mov Disord, 27, 608, 10.1002/mds.24954

Schenck, 2013, Delayed emergence of a parkinsonian disorder or dementia in 81 of older males initially diagnosed with idiopathic rapid eye movement sleep behavior disorder: 16-year update on a previously reported series., Sleep Med, 14, 744, 10.1016/j.sleep.2012.10.009

Iranzo, 2013, Neurodegenerative disease status and post-mortem pathology in idiopathic rapid-eye-movement sleep behaviour disorder: an observational cohort study., Lancet Neurol, 12, 443, 10.1016/S1474-4422(13)70056-5

Postuma, 2009, Quantifying the risk of neurodegenerative disease in idiopathic REM sleep behavior disorder., Neurology, 72, 1296, 10.1212/01.wnl.0000340980.19702.6e

Wing, 2012, Prospective outcome of rapid eye movement sleep behaviour disorder: psychiatric disorders as a potential early marker of Parkinsons disease., J Neurol Neurosurg Psychiatry, 83, 470, 10.1136/jnnp-2011-301232

Postuma, 2013, Antidepressants and REM sleep behavior disorder: isolated side effect or neurodegenerative signal S, leep, 36, 1579

Boot, 2012, Probable rapid eye movement sleep behavior disorder increases risk for mild cognitive impairment and Parkinson disease: a population-based study., Ann Neurol, 71, 49, 10.1002/ana.22655

Iranzo, 2010, Decreased striatal dopamine transporters uptake and substantia nigra hyperechogenicity as risk markers of synucleinopathy in patients with idiopathic rapid-eye-movement sleep behaviour disorder: a prospective study., Lancet Neurol, 9, 1070, 10.1016/S1474-4422(10)70216-7

Dang-Vu, 2012, Hippocampal perfusion predicts impending neurodegeneration in REM sleep behavior disorder., Neurology, 79, 2302, 10.1212/WNL.0b013e318278b658

Postuma, 2011, Olfaction and color vision identify impending neurodegeneration in REM behavior disorder., Ann Neurol, 69, 811, 10.1002/ana.22282

Postuma, 2012, How does parkinsonism start Prodromal parkinsonism motor changes in idiopathic REM sleep behaviour disorder., Brain, 135, 1860, 10.1093/brain/aws093

Ross, 2005, Association of olfactory dysfunction with risk of future Parkinsons disease., Mov Disord, 20, S129

Ross, 2006, Association of olfactory dysfunction with incidental Lewy bodies., Mov Disord, 21, 2062, 10.1002/mds.21076

Ponsen, 2004, Idiopathic hyposmia as a preclinical sign of Parkinsons disease., Ann Neurol, 56, 173, 10.1002/ana.20160

Berg, 2012, Defining at-risk populations for Parkinsons disease: lessons from ongoing studies., Mov Disord, 27, 656, 10.1002/mds.24985

Siderowf, 2012, Impaired olfaction and other prodromal features in the Parkinson At-Risk Syndrome Study., Mov Disord, 27, 406, 10.1002/mds.24892

Ponsen, 2009, Hyposmia and executive dysfunction as predictors of future Parkinsons disease: a prospective study., Mov Disord, 24, 1060, 10.1002/mds.22534

Pouclet, 2012, A comparison between rectal and colonic biopsies to detect Lewy pathology in Parkinsons disease., Neurobiol Dis, 45, 305, 10.1016/j.nbd.2011.08.014

Beach, 2010, Multiorgan distribution of phosphorylated alpha-synuclein histopathology in subjects with Lewy body disorders., Acta Neuropathol, 119, 689, 10.1007/s00401-010-0664-3

Abbott, 2007, Bowel movement frequency in late-life and incidental Lewy bodies., Mov Disord, 22, 1581, 10.1002/mds.21560

Shannon, 2012, Is alpha-synuclein in the colon a biomarker for premotor Parkinsons disease Evidence from 3 cases., Mov Disord, 27, 716, 10.1002/mds.25020

Savica, 2009, Medical records documentation of constipation preceding Parkinson disease: a case-control study., Neurology, 73, 1752, 10.1212/WNL.0b013e3181c34af5

Gao, 2011, A prospective study of bowel movement frequency and risk of Parkinsons disease., Am J Epidemiol, 174, 546, 10.1093/aje/kwr119

Leentjens, 2003, Higher incidence of depression preceding the onset of Parkinsons disease: a register study., Mov Disord, 18, 414, 10.1002/mds.10387

Alonso, 2009, Use of antidepressants and the risk of Parkinsons disease: a prospective study., J Neurol Neurosurg Psychiatry, 80, 671, 10.1136/jnnp.2008.152983

Fang, 2010, Depression and the subsequent risk of Parkinsons disease in the NIH-AARP Diet and Health Study., Mov Disord, 25, 1157, 10.1002/mds.23092

Weisskopf, 2003, Prospective study of phobic anxiety and risk of Parkinsons disease., Mov Disord, 18, 646, 10.1002/mds.10425

Bower, 2010, Anxious personality predicts an increased risk of Parkinsons disease., Mov Disord, 25, 2105, 10.1002/mds.23230

Ishihara, 2006, What is the evidence for a premorbid parkinsonian personality: a systematic review., Mov Disord, 21, 1066, 10.1002/mds.20980

OSullivan, 2008, Nonmotor symptoms as presenting complaints in Parkinsons disease: a clinicopathological study., Mov Disord, 23, 101, 10.1002/mds.21813

Chaudhuri, 2006, International multicenter pilot study of the first comprehensive self-completed nonmotor symptoms questionnaire for Parkinsons disease: the NMSQuest study., Mov Disord, 21, 916, 10.1002/mds.20844

Chaudhuri, 2007, The metric properties of a novel nonmotor symptoms scale for Parkinsons disease: results from an international pilot study., Mov Disord, 22, 1901, 10.1002/mds.21596

Goetz, 2008, Movement Disorder Society-sponsored revision of the Unified Parkinsons Disease Rating Scale (MDS-UPDRS): scale presentation and clinimetric testing results., Mov Disord, 23, 2129, 10.1002/mds.22340

Duncan, 2014, Health-related quality of life in early Parkinsons disease: the impact of nonmotor symptoms., Mov Disord, 29, 195, 10.1002/mds.25664

Muller, 2011, Autonomic and sensory symptoms and signs in incident, untreated Parkinsons disease: frequent but mild., Mov Disord, 26, 65, 10.1002/mds.23387

Barone, 2009, The PRIAMO study: a multicenter assessment of nonmotor symptoms and their impact on quality of life in Parkinsons disease., Mov Disord, 24, 1641, 10.1002/mds.22643

Erro, 2013, Nonmotor symptoms in early Parkinsons disease: a 2-year follow-up study on previously untreated patients., J Neurol Neurosurg Psychiatry, 84, 14, 10.1136/jnnp-2012-303419

Khoo, 2013, The spectrum of nonmotor symptoms in early Parkinson disease., Neurology, 80, 276, 10.1212/WNL.0b013e31827deb74

Kim, 2009, Nonmotor symptoms in de novo Parkinson disease before and after dopaminergic treatment., J Neurol Sci, 287, 200, 10.1016/j.jns.2009.07.026

Aarsland, 2009, Cognitive impairment in incident, untreated Parkinson disease: the Norwegian ParkWest study., Neurology, 72, 1121, 10.1212/01.wnl.0000338632.00552.cb

Elgh, 2009, Cognitive function in early Parkinsons disease: a population-based study., Eur J Neurol, 16, 1278, 10.1111/j.1468-1331.2009.02707.x

Foltynie, 2004, The cognitive ability of an incident cohort of Parkinsons patients in the UK. The CamPaIGN study., Brain, 127, 550, 10.1093/brain/awh067

Muslimovic, 2005, Cognitive profile of patients with newly diagnosed Parkinson disease., Neurology, 65, 1239, 10.1212/01.wnl.0000180516.69442.95

Litvan, 2012, Diagnostic criteria for mild cognitive impairment in Parkinsons disease: Movement Disorder Society Task Force guidelines., Mov Disord, 27, 349, 10.1002/mds.24893

Yarnall, 2014, Characterizing mild cognitive impairment in incident Parkinson disease: the ICICLE-PD study., Neurology, 82, 308, 10.1212/WNL.0000000000000066

Williams-Gray, 2009, The distinct cognitive syndromes of Parkinsons disease: 5 year follow-up of the CamPaIGN cohort., Brain, 132, 2958, 10.1093/brain/awp245

Williams-Gray, 2013, The CamPaIGN study of Parkinsons disease: 10-year outlook in an incident population-based cohort., J Neurol Neurosurg Psychiatry, 84, 1258, 10.1136/jnnp-2013-305277

Pedersen, 2013, Prognosis of mild cognitive impairment in early Parkinson disease: the Norwegian ParkWest Study., JAMA Neurol, 70, 1, 10.1001/jamaneurol.2013.2110

Broeders, 2013, Evolution of mild cognitive impairment in Parkinson disease., Neurology, 81, 346, 10.1212/WNL.0b013e31829c5c86

Apostolova, 2010, Hippocampal, caudate, and ventricular changes in Parkinsons disease with and without dementia., Mov Disord, 25, 687, 10.1002/mds.22799

Bruck, 2004, Hippocampal and prefrontal atrophy in patients with early nondemented Parkinsons disease is related to cognitive impairment., J Neurol Neurosurg Psychiatry, 75, 1467, 10.1136/jnnp.2003.031237

Dalaker, 2010, Gray matter correlations of cognition in incident Parkinsons disease., Mov Disord, 25, 629, 10.1002/mds.22867

Hattori, 2012, Cognitive status correlates with white matter alteration in Parkinsons disease., Hum Brain Mapp, 33, 727, 10.1002/hbm.21245

Song, 2011, The pattern of cortical atrophy in patients with Parkinsons disease according to cognitive status., Mov Disord, 26, 289, 10.1002/mds.23477

Alves, 2013, Cerebrospinal fluid amyloid-beta and phenotypic heterogeneity in de novo Parkinsons disease., J Neurol Neurosurg Psychiatry, 84, 537, 10.1136/jnnp-2012-303808

Fabbrini, 2002, Excessive daytime sleepiness in de novo and treated Parkinsons disease., Mov Disord, 17, 1026, 10.1002/mds.10193

Giganti, 2013, Daytime course of sleepiness in de novo Parkinsons disease patients., J Sleep Res, 22, 197, 10.1111/jsr.12000

Erro, 2012, Link between nonmotor symptoms and cognitive dysfunctions in de novo, drug-naive PD patients., J Neurol, 259, 1808, 10.1007/s00415-011-6407-0

Weintraub, 2010, Impulse control disorders in Parkinson disease: a cross-sectional study of 3090 patients., Arch Neurol, 67, 589, 10.1001/archneurol.2010.65

Antonini, 2011, Impulsivity and compulsivity in drug-naive patients with Parkinsons disease., Mov Disord, 26, 464, 10.1002/mds.23501

Weintraub, 2013, Screening for impulse control symptoms in patients with de novo Parkinson disease: a case-control study., Neurology, 80, 176, 10.1212/WNL.0b013e31827b915c

Mollenhauer, 2013, Nonmotor and diagnostic findings in subjects with de novo Parkinson disease of the DeNoPa cohort., Neurology, 81, 1226, 10.1212/WNL.0b013e3182a6cbd5

Braak, 2004, Stages in the development of Parkinsons disease-related pathology., Cell Tissue Res, 318, 121, 10.1007/s00441-004-0956-9

Del Tredici, 2010, Lewy pathology in the submandibular gland of individuals with incidental Lewy body disease and sporadic Parkinsons disease., Acta Neuropathol, 119, 703, 10.1007/s00401-010-0665-2

Del Tredici, 2012, Lewy pathology and neurodegeneration in premotor Parkinsons disease., Mov Disord, 27, 597, 10.1002/mds.24921