Preferential expression and activity of multidrug resistance gene 1 product (P-glycoprotein), a functionally active efflux pump, in human CD8 + T cells: A role in cytotoxic effector function
Tóm tắt
Từ khóa
Tài liệu tham khảo
Ng WF, Sarangi F, Zastawny RL, Veinot-Drebot L, Ling V: Identification of members of the P-glycoprotein multigene family. Mol Cell Biol 9:1224?1232, 1989
Chen CJ, Clark D, Ueda K, Pastan I, Gottesman MM, Roninson I: Genomic organization and evolution of the human multidrug resistance (mdr 1) gene. Proc Am Assoc Cancer Res 30:499, 1989
Juranka PF, Zastawny RL, Ling V: P-glycoprotein: multidrug resistance and a superfamily of membrane associated transport protein. FASEB J 3:2583?2592, 1989
Gros P, Croop J, Housman D: Mammalian multidrug resistance gene: Complete cDNA sequence indicates strong homology to bacterial transport proteins. Cell 47:371?380, 1986
Chen C-J, Chin JE, Ueda K, Clark DP, Pastan I, Gottesman MM: Internal duplication and homology with bacterial transport proteins in themdr 1 (p-glycoprotein) gene from multidrug resistant human cells. Cell 47:381?389, 1986
Gerlach JH, Endicott JA, Juranka PF, Henderson G, Sarangi F, Deuchars KL, Ling V: Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance. Nature 324:485?489, 1986
Wilson CM, Serrano AE, Wesley A, Bogenschutz MP, Shanker AH, Wirth DF: Amplification of a gene related to mammalianmdr genes in drug-resistantPlasmodium falciparum. Science 244:1184?1186, 1989
Foote SJ, Thompson JK, Cowman AF, Kemp DJ: Amplification of the multidrug resistant gene in some chloroquine-resistant isolates ofP. falciparum. Cell 57:921?930, 1989
Skovsgaard T: Mechanisms of resistance to daunorubicin in Ehrlich ascites tumor cells. Cancer Res 38:1785?1791, 1978
Inaba M, Kobayashi H, Sakurai Y, Johnson R: Active efflux of daunorubicin and adriamycin in sensitive and resistant sublines of P388 leukemia. Cancer Res 39:2200?2203, 1979
Fojo A, Akiyama S, Gottesman M, Pastan I: Reduced drug accumulation in multiple drug-resistant human KB carcinoma cell lines. Cancer Res 45:3002?3007, 1985
Gros P, Croop J, Roninson I, Varshavsky A, Hausman DE: Isolation and characterization of DNA sequences amplified in multidrug resistant hamster cells. Proc Natl Acad Sci USA 83:337?341, 1986
Cordon-Cardo C, O'Brian JP, Casals D, Ritter-Grauer L, Biedler JL, Melamed MR, Bertino JR: Multidrug resistance gene (P-glycoprotein) is expressed by endothelial cells at blood brain barrier sites. Proc Natl Acad Sci USA 86:695?698, 1989
Thiebaut T, Tsuruo T, Hamada H, Gottesman MM, Pastan I, Willingham MC: Cellular localization of multidrug resistant gene product P-glycoprotein in normal human tissues. Proc Natl Acad Sci USA 84:7734?7738, 1987
Arceci RJ, Croop JM, Horwitz SB, Housman D: The gene encoding multidrug resistance is induced and expressed at high levels during pregnancy in the secretory epithelium of the uterus. Proc Natl Acad Sci USA 85:4350?4354, 1988
Fojo AT, Ueda K, Slamon DJ, Poplack DG, Gottesman MM, Pastan I: Expression of a multidrug-resistance gene in human tumors and tissues. Proc Natl Acad Sci USA 84:265?269, 1987
Cordon-Cardo C, O'Brien JP, Boccia J, Casals D, Bertino JR, Melamed MR: Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues. J Histochem Cytochem 38:1277?1287, 1990
Sugawara I, Kataoka I, Morishita Y, Hamada H, Tsuruo T, Itoyama S, Mori S: Tissue distribution of P-glycoprotein encoded by a multidrug resistant gene as revealed by a monoclonal antibody, MRK16. Cancer Res 48:1926?1929, 1988
Sugawara I, Nakahama M, Hamada H, Tsuruo T, Mori S: Apparent stronger expression in the human adrenal cortex than in the human adrenal medulla of Mr 170,000?180,000 P-glycoprotein. Cancer Res 48:4611?4614, 1988
Hamada H, Tsuruo T: Functional role for the 170?180 Kda glycoprotein specific to drug resistant tumor cells as treated by monoclonal antibodies. Proc Natl Acad Sci USA 83:7785?7789, 1986
Noonan KE, Beck C, Holzmayer TA, Chin JE, Wunder JS, Andrulis IL, Gazdar AF, Willman CL, Griffith B, Von Hoff DD, Roninson IB: Quantitative analysis ofMDR 1 (multidrug resistance) gene expression in human polymerase chain reaction. Proc Natl Acad Sci USA 87:7160?7164, 1990
Kessel D, Beck WT, Kukuraga D, Schulz V: Characterization of multidrug resistance by fluorescent dyes. Cancer Res 51:4665?4670, 1991
Foxwell BMJ, Mackie A, Ling V, Ryffel B: Identification of the multidrug related P-glycoprotein as a cyclosporin binding protein. Mol Pharmacol 36:543?546, 1989
Sharma S, Gupta S: Antigen-specific primary cytotoxic T lymphocyte (CTL) responses in acquired immunodeficiency syndrome (AIDS) and AIDS-related complex (ARC). Clin Exp Immunol 62:296?303, 1985
Scotto KW, Biedler JL, Melera PW: Amplification and expression of gene associated with multidrug resistance in mammalian cells. Science 232:751?755, 1986
Scheper RJ, Bulte JWM, Brakkee JGP, Quak JJ, van der Schoot E, Balm AJM, Meijer CJLM, Broxterman HL, Kuiper CM, Lankelma J, Pinedo HM: Monoclonal antibody JSB-1 detects a highly conserved epitope on the tumors by P-glycoprotein associated with multi-drug resistance. Int J Cancer 42:389?394, 1988
Goldstein LJ, Galski H, Fojo A, Willingham M, Lai S-L, Gazdar A, Pirker R, Green A, Crist W, Brodeur GM, Leiber M, Cossman J, Gottesman M, Pastan I: Expression of multidrug resistance gene in human cancer. J Natl Cancer Inst 81:116?124, 1989
Gupta S, Tsuruo T, Gollapudi S: Expression of multidrug resistant gene-1 (mdr 1) in human T cell subsets. Regulation by cyclosporin A and role of protein kinase C isoforms. Adv Exp Med Biol 323:39?47, 1992
Chaudhary PM, Roninson IB: Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells. Cell 66:85?94, 1991
Neyfakh AA, Serpinskaya AS, Chervonsky AV, Apasov SG, Kazarov AR: Multidrug resistant phenotype of a subpopulation of T lymphocytes without drug selection. Exp Cell Res 185:496?505, 1989
Coon JS, Wang Y, Bines SD, Markham PN, Chong ASF, Gebel HM: Multidrug resistance activity in human lymphocytes. Hum Immunol 32:134?140, 1991
Gupta S, Gollapudi S: Heterogeneity of MDR cells demonstrated by flow cytometry. Fed Proc 4:1586, 1990
Podack E, Hengartner H, Lichtenheld MG: A central role of perforin in cytolysis. Annu Rev Immunol 9:129?157, 1991