Predictors of slow progression to diabetes in children with multiple islet autoantibodies

Journal of Autoimmunity - Tập 72 - Trang 113-117 - 2016
Andrea K. Steck1, Fran Dong1, Kathleen Waugh1, Brigitte I. Frohnert1, Liping Yu1, Jill M. Norris2, Marian J. Rewers1
1Barbara Davis Center for Childhood Diabetes, University of Colorado School of Medicine, Aurora, CO, USA
2Colorado School of Public Health, University of Colorado Denver, Aurora, CO, USA

Tài liệu tham khảo

Orban, 2009, Pancreatic islet autoantibodies as predictors of type 1 diabetes in the Diabetes Prevention Trial-Type 1, Diab. Care, 32, 2269, 10.2337/dc09-0934 Siljander, 2009, Predictive characteristics of diabetes-associated autoantibodies among children with HLA-conferred disease susceptibility in the general population, Diabetes, 58, 2835, 10.2337/db08-1305 Bingley, 2006, Progression to type 1 diabetes in islet cell antibody-positive relatives in the European Nicotinamide Diabetes Intervention Trial: the role of additional immune, genetic and metabolic markers of risk, Diabetology, 49, 881, 10.1007/s00125-006-0160-4 Yu, 2001, Expression of GAD65 and islet cell antibody (ICA512) autoantibodies among cytoplasmic ICA+ relatives is associated with eligibility for the Diabetes Prevention Trial-Type 1, Diabetes, 50, 1735, 10.2337/diabetes.50.8.1735 Greenbaum, 1992, J. Clin. Endocrinol. Metab., 74, 1040 Baekkeskov, 1990, Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase [published erratum appears in Nature 1990 Oct 25;347(6295):782], Nature, 347, 151, 10.1038/347151a0 Gianani, 1995, ICA512 autoantibody radioassay, diab, 44, 1340, 10.2337/diab.44.11.1340 Wenzlau, 2008, SlC30A8 is a major target of humoral autoimmunity in type 1 diabetes and a predictive marker in prediabetes, Ann. N. Y. Acad. Sci., 1150, 256, 10.1196/annals.1447.029 Ziegler, 2013, Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children, JAMA, 309, 2473, 10.1001/jama.2013.6285 Vardi, 1988, Concentration of insulin autoantibodies at onset of type I diabetes. Inverse log-linear correlation with age, Diab. Care, 11, 736, 10.2337/diacare.11.9.736 Steck, 2011, Age of islet autoantibody appearance and mean levels of insulin, but not GAD or IA-2 autoantibodies, predict age of diagnosis of type 1 diabetes: diabetes autoimmunity study in the young, Diab. Care, 34, 1397, 10.2337/dc10-2088 Achenbach, 2013, Characteristics of rapid vs slow progression to type 1 diabetes in multiple islet autoantibody-positive children, Diabetology, 56, 1615, 10.1007/s00125-013-2896-y Rewers, 1996, Newborn screening for HLA markers associated with iddm: diabetes autoimmunity study in the young (DAISY), Diabetology, 39, 807, 10.1007/s001250050514 Yu, 1996, Antiislet autoantibodies usually develop sequentially rather than simultaneously, J. Clin. Endocrinol. Metab., 81, 4264 Steck, 2015, Predictors of progression from the appearance of islet autoantibodies to early childhood diabetes: the environmental Determinants of diabetes in the young (TEDDY), Diab. Care, 38, 808, 10.2337/dc14-2426 Yu, 1996, Modification to Combined GAD65/ICA512 Radioassay for general population screening, Diabets, 45 Yu, 2012, Distinguishing persistent insulin autoantibodies with differential risk: nonradioactive bivalent proinsulin/insulin autoantibody assay, Diabetes, 61, 179, 10.2337/db11-0670 Miao, 2013, GAD65 autoantibodies detected by electrochemiluminescence (ECL) assay identify high risk for type 1 diabetes, Diabetes, 62, 4174, 10.2337/db13-0534 Mirel, 2002, Association of IL4R haplotypes with type 1 diabetes, Diabetes, 51, 3336, 10.2337/diabetes.51.11.3336 Steck, 2014, Improving prediction of type 1 diabetes by testing non-HLA genetic variants in addition to HLA markers, Pediatr. Diab., 15, 355, 10.1111/pedi.12092 Hummel, 2004, Brief communication: early appearance of islet autoantibodies predicts childhood type 1 diabetes in offspring of diabetic parents, Ann. Intern. Med., 140, 882, 10.7326/0003-4819-140-11-200406010-00009 Achenbach, 2004, Stratification of type 1 diabetes risk on the basis of islet autoantibody characteristics, Diabetes, 53, 384, 10.2337/diabetes.53.2.384 Decochez, 2002, IA-2 autoantibodies predict impending type I diabetes in siblings of patients, Diabetology, 45, 1658, 10.1007/s00125-002-0949-8 Yu, 2012, Zinc transporter-8 autoantibodies improve prediction of type 1 diabetes in relatives positive for the standard biochemical autoantibodies, Diab. Care, 35, 1213, 10.2337/dc11-2081 Sosenko, 2013, The prediction of type 1 diabetes by multiple autoantibody levels and their incorporation into an autoantibody risk score in relatives of type 1 diabetic patients, Diab. Care, 36, 2615, 10.2337/dc13-0425 Nakayama, 2005, Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice, Nature, 435, 220, 10.1038/nature03523 Sosenko, 2008, A risk score for type 1 diabetes derived from autoantibody-positive participants in the diabetes prevention trial-type 1, Diab. Care, 31, 528, 10.2337/dc07-1459 Sosenko, 2012, The application of the diabetes prevention trial-type 1 risk score for identifying a preclinical state of type 1 diabetes, Diab. Care, 35, 1552, 10.2337/dc12-0011 Yu, 2013, Proinsulin/insulin autoantibodies measured with electrochemiluminescent assay are the earliest indicator of prediabetic islet autoimmunity, Diab. Care, 36, 2266, 10.2337/dc12-2245