Predictivity of in vitro non-clinical cardiac contractility assays for inotropic effects in humans — A literature search
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Adeyemi, 2009, QA interval as an indirect measure of cardiac contractility in the conscious telemeterised rat: Model optimization and evaluation, Journal of Pharmacological and Toxicological Methods, 60, 159, 10.1016/j.vascn.2009.03.006
Ahmad, 2001, Congestive heart failure associated with itraconazole, Lancet, 357, 1766, 10.1016/S0140-6736(00)04891-1
Anning, 1995, Enhancement of left ventricular relaxation in the isolated heart by an angiotensin-converting enzyme inhibitor, Circulation, 92, 2660, 10.1161/01.CIR.92.9.2660
Antila, 1995, Haemodynamic interactions of a new calcium sensitizing drug levosimendan and captopril, European Journal of Clinical Pharmacology, 49, 451, 10.1007/BF00195930
Arrowsmith, 2013, Phase II and phase III attrition rates 2011–2012, Nature Reviews Drug Discovery, 12, 569, 10.1038/nrd4090
Baruch, 2000, Pharmacodynamic effects of milrinone with and without a bolus loading infusion, American Heart Journal, 141, 266
Bell, 2011, Retrograde heart perfusion: The Langendorff technique of isolated heart perfusion, Journal of Molecular and Cellular Cardiology, 50, 940, 10.1016/j.yjmcc.2011.02.018
Belz, 1988, The relationship between pharmacokinetics and pharmacodynamics of enoximone in healthy man, European Journal of Clinical Pharmacology, 35, 631, 10.1007/BF00637599
Blasi, 2012, Sunitinib, a receptor tyrosine kinase inhibitor, increases blood pressure in rats without associated changes in cardiac structure and function, Cardiovascular Therapeutics, 30, 287, 10.1111/j.1755-5922.2011.00278.x
Boknik, 1997, Mechanisms of the contractile effects of levosimendan in the mammalian heart, Journal of Pharmacology & Experimental Therapeutics, 280, 277
Boudot, 1978, Cardiovascular effects of diltiazem, a calcium antagonist, on isolated heart muscle preparations and in anaesthetized and pithed rats
Bourassa, 1980, Hemodynamics and coronary flow following diltiazem administration in anesthetized dogs and in humans, Chest, 78, 224, 10.1378/chest.78.1.224
Brown, 1985, Concentration–response curves for positive inotropic agents before and after ouabain pretreatment, Cardiovascular Research, 19, 288, 10.1093/cvr/19.5.288
Brunkhorst, 1989, Relation of positive inotropic and chronotropic effects of pimobendan, UD-CG 212 Cl, milrinone and other phosphodiesterase inhibitors to phosphodiesterase III inhibition in guinea-pig heart, Naunyn-Schmiedeberg's Archives of Pharmacology, 339, 575, 10.1007/BF00167264
Caiozzo, 2002, Plasticity of skeletal muscle phenotype: Mechanical consequences, Muscle and Nerve, 26, 740, 10.1002/mus.10271
Cambridge, 1986, Evaluation of the QA interval as an index of cardiac contractility in anaesthetised dogs: Responses to change in cardiac loading and heart rate, Cardiovascular Research, 20, 444, 10.1093/cvr/20.6.444
Cavero, 1980, Effects of clonidine on canine cardiac neuroeffector structures controlling heart rate, British Journal of Pharmacology, 70, 269, 10.1111/j.1476-5381.1980.tb07932.x
Chu, 1999, Cardiovascular effect and simultaneous pharmacokinetic and pharmacodynamics modeling of pimobendan in healthy normal subjects, American Society for Pharmacology and Experimental Therapeutics, 27, 701
Cook, 2014, Lessons learned from the fate of AstraZeneca's drug pipeline: A five-dimensional framework, Nature Reviews Drug Discovery, 13, 419, 10.1038/nrd4309
Di Lorenzo, 2009, Cardiovascular toxicity following sunitinib therapy in metastatic renal cell carcinoma: A multicenter analysis, Annals of Oncology, 20, 1535, 10.1093/annonc/mdp025
Doherty, 2013, Multi-parameter in vitro toxicity testing of crizotinib, sunitinib, erlotinib, and nilotinib in human cardiomyocytes, Toxicology and Applied Pharmacology, 272, 245, 10.1016/j.taap.2013.04.027
Edelson, 1981, Relationship between amrinone plasma concentration and cardiac index, Clinical Pharmacology and Therapeutics, 29, 723, 10.1038/clpt.1981.102
Eichelbaum, 1980, Effects of verapamil on P–R-intervals in relation to verapamil plasma levels following single i.v. and oral administration and during chronic treatment, Klinische Wochenschrift, 58, 919, 10.1007/BF01477049
Ertl, 1991, Differential electrophysiologic and inotropic effects of phenylephrine in atrial and ventricular heart muscle preparations from rats, Naunyn-Schmiedeberg's Archives of Pharmacology, 344, 574, 10.1007/BF00170655
Franco-Cereceda, 1985, Calcitonin gene-related peptide (CGRP) and capsaicin-induced stimulation of heart contractile rate and force, Naunyn-Schmiedeberg's Archives of Pharmacology, 331, 146, 10.1007/BF00634231
Fujino, 1988, Sensitization of dog and guinea pig heart myofilaments to Ca2+ activation and the inotropic effect of pimobendan: Comparison with milrinone, Circulation Research, 63, 911, 10.1161/01.RES.63.5.911
Gharanei, 2014, Investigation into the cardiotoxic effects of doxorubicin on contractile function and the protection afforded by cyclosporin A using the work-loop assay, Toxicology In Vitro, 28, 722, 10.1016/j.tiv.2014.01.011
Gharanei, 2012, Doxorubicin induced myocardial injury is exacerbated following ischaemic stress via opening of the mitochondrial permeability transition pore, Toxicology and Applied Pharmacology, 268, 149, 10.1016/j.taap.2012.12.003
Grant, 1978, Effects of droperidol on depolarization-induced automaticity, maximum upstroke velocity (Vmax) and the kinetics of recovery of Vmax in guinea-pig ventricular myocardium, Journal of Pharmacology and Experimental Therapeutics, 205, 193
Guo, 2011, Estimating the risk of drug-induced proarrhythmia using human induced pluripotent stem cell-derived cardiomyocytes, Toxicological Sciences, 123, 281, 10.1093/toxsci/kfr158
Haglund, 1980, Time course of blood pressure, pulse rate, plasma renin and metoprolol treatment, European Journal of Clinical Pharmacology, 17, 321, 10.1007/BF00558443
Hamlin, 2012, dP/dtmax — A measure of ‘baroinometry’, Journal of Pharmacological and Toxicological Methods, 66, 63, 10.1016/j.vascn.2012.01.001
Hansen, 1984, Influence of atenolol and nifedipine on digoxin-induced inotropism in humans, British Journal of Clinical Pharmacology, 18, 817, 10.1111/j.1365-2125.1984.tb02550.x
Harding, 2007, The human embryonic stem cell-derived cardiomyocyte as a pharmacological model, Pharmacology & Therapeutics, 113, 341, 10.1016/j.pharmthera.2006.08.008
Harmer, 2012, Validation of an in vitro contractility assay using canine ventricular myocytes, Toxicology and Applied Pharmacology, 260, 162, 10.1016/j.taap.2012.02.007
Hermiller, 1983, Clonidine in congestive heart failure: A vasodilator with negative inotropic effects, American Journal of Cardiology, 51, 791, 10.1016/S0002-9149(83)80135-0
Hill, 2001, Attenuation of verapamil-induced myocardial toxicity in an ex-vivo rat model using a verapamil-specific ovine immunoglobin, Academic Emergency Medicine, 8, 950, 10.1111/j.1553-2712.2001.tb01092.x
Himmel, 2013, Drug-induced functional cardiotoxicity screening in stem cell-derived human and mouse cardiomyocytes: Effects of reference compounds, Journal of Pharmacological and Toxicological Methods, 68, 97, 10.1016/j.vascn.2013.05.005
Hirakawa, 1977, In situ measurement of papillary muscle dynamics in the dog left ventricle, American Journal of Physiology, 233, H384
Holck, 1986, Inhibition of the myocardial Ca2+ inward current by the class 1 antiarrhythmic agent, cibenzoline, British Journal of Pharmacology, 87, 705, 10.1111/j.1476-5381.1986.tb14588.x
Holtzman, 1989, The pharmacodynamic and pharmacokinetic interaction between single doses of flecainide acetate and verapamil: Effects on cardiac function and drug clearance, Clinical Pharmacology and Therapeutics, 46, 26, 10.1038/clpt.1989.102
Honerjäger, 1986, Negative inotropic effects of tetrodotoxin and seven class I antiarrhythmic drugs in relation to sodium channel blockade, Naunyn-Schmiedeberg's Archives of Pharmacology, 332, 184, 10.1007/BF00511411
Houk, 2009, A population pharmacokinetic meta-analysis of sunitinib malate (SU11248) and its primary metabolite (SU12662) in healthy volunteers and oncology patients, Clinical Cancer Research, 15, 2497, 10.1158/1078-0432.CCR-08-1893
Huizer, 1992, Captopril inhibits angiotensin I-induced coronary flow reduction in isolated rat heart but has no effect on contractility or energy metabolism, European Heart Journal, 13, 109, 10.1093/oxfordjournals.eurheartj.a060029
ICH S7A, 2000, International conference on harmonization
Ito, 1996, Possible involvement of altered Na+–Ca2+ exchange in negative inotropic effects of class I antiarrhythmic drugs on rabbit and rat ventricles, Journal of Cardiovascular Pharmacology, 27, 355, 10.1097/00005344-199603000-00007
James, 1996, Isometric and isotonic muscle properties as determinants of work loop power output, Pflügers Archiv, 432, 767, 10.1007/s004240050197
Josephson, 1985, Mechanical power output from striated muscle during cyclic contraction, Journal of Experimental Biology, 493, 10.1242/jeb.114.1.493
Josephson, 1993, Contraction dynamics and power output of skeletal muscle, Annual Review of Physiology, 55, 527, 10.1146/annurev.ph.55.030193.002523
Khan, 2013, The case for induced pluripotent stem cell-derived cardiomyocytes in pharmacological screening, British Journal of Pharmacology, 169, 304, 10.1111/j.1476-5381.2012.02118.x
Khatib, 2003, Effects of glyburide (glibenclamide) on myocardial function in Langendorff perfused rabbit heart and on myocardial contractility and slow calcium current in guinea-pig single myocytes, Molecular and Cellular Biochemistry, 242, 81, 10.1023/A:1021137712039
Kondo, 1990, Negative inotropic effects of disopyramide on guinea-pig papillary muscles, British Journal of Pharmacology, 101, 789, 10.1111/j.1476-5381.1990.tb14158.x
Kraushaar, 2012, Cardiac safety pharmacology: From human ether-a-gogo related gene channel block towards induced pluripotent stem cell based disease models, Expert Opinion on Drug Safety, 11, 285, 10.1517/14740338.2012.639358
Landzberg, 1991, Effects of myocardial α1-adrenergic receptor stimulation and blockade on contractility in humans, Circulation, 84, 1608, 10.1161/01.CIR.84.4.1608
Layland, 1999, Positive force- and [Ca2+]i-frequency relationships in rat ventricular trabeculae at physiological frequencies, American Journal of Physiology, 276, H9
Layland, 2000, Effects of 1- or -adrenoceptor stimulation on work-loop and isometric contractions of isolated rat cardiac trabeculae, Journal of Physiology, 524, 205, 10.1111/j.1469-7793.2000.t01-1-00205.x
Layland, 1995, The length dependence of work production in rat papillary muscles in vitro, Journal of Experimental Biology, 198, 2491, 10.1242/jeb.198.12.2491
Lee, 2011, Calcium homeostasis in human induced pluripotent stem cell-derived cardiomyocytes, Stem Cell Reviews, 7, 976, 10.1007/s12015-011-9273-3
Lewis, 1985, Timolol and atenolol: Relationships between oxidation phenotype, pharmacokinetics and pharmacodynamics, British Journal of Clinical Pharmacology, 19, 329, 10.1111/j.1365-2125.1985.tb02651.x
Liljedahl, 2009, The effects of antihypertensive treatment on the Doppler-derived myocardial index in patients with hypertensive left ventricular hypertrophy: Results from the Swedish Irbesartan in left ventricular hypertrophy investigation versus atenolol (SILVHIA), Echocardiology: A Journal of Cardiovascular Ultrasound and Allied Technology, 26, 753, 10.1111/j.1540-8175.2008.00886.x
Lilleberg, 1994, Haemodynamic dose-efficacy of Levosimendan in healthy volunteers, European Journal Clinical Pharmacology, 47, 267, 10.1007/BF02570507
Lu, 2000, Enoximone echocardiography for predicting recovery of left ventricular dysfunction after revascularisation. A novel test for detecting myocardial viability, Circulation, 101, 1255, 10.1161/01.CIR.101.11.1255
Lüllman, 1973, The time courses of the changes in contractile force and in transmembrane potentials induced by cardiac glycosides in the guinea-pig papillary muscle, British Journal of Pharmacology, 49, 377, 10.1111/j.1476-5381.1973.tb17248.x
Lumley, 1977, Analysis of the inotropic:chronotropic selectivity of dobutamine and dopamine in anaesthetised dogs and guinea-pig isolated atria, Cardiovascular Research, 11, 17, 10.1093/cvr/11.1.17
Marcovitz, 1997, Impact of metoprolol on heart rate, blood pressure, and contractility in normal subjects during dobutamine stress echocardiography, American Journal of Cardiology, 80, 386, 10.1016/S0002-9149(97)00376-7
Markert, 2007, The value added by measuring myocardial contractility ‘in vivo’ in safety pharmacological profiling of drug candidates, Journal of Pharmacological and Toxicological Methods, 56, 203, 10.1016/j.vascn.2007.03.004
Matsui, 1999, Effects of pimobendan on the L-type Ca2+ current and developed tension in guinea-pig ventricular myocytes and papillary muscle: Comparison with IBMX, milrinone, and cilostazol, Cardiovascular Drugs and Therapy, 13, 105, 10.1023/A:1007779908346
Matsuoka, 1991, Comparison of Ca2+ channel inhibitory effects of cibenzoline with verapamil on guinea-pig heart, General Pharmacology: The Vascular System, 22, 87, 10.1016/0306-3623(91)90314-V
Mellors, 2001, The energetics of rat papillary muscles undergoing realistic strain patterns, Journal of Experimental Biology, 204, 3765, 10.1242/jeb.204.21.3765
Mellors, 2001, Comparison of the efficiency of rat papillary muscles during after loaded isotonic contractions and contractions with sinusoidal length changes, Journal of Experimental Biology, 204, 1765, 10.1242/jeb.204.10.1765
Miller, 1975, Clinical use of d sodium nitroprusside in chronic ischemic heart disease. Effects on peripheral vascular resistance and venous tone and on ventricular volume, pump and mechanical performance, Circulation, 51, 328, 10.1161/01.CIR.51.2.328
Miller, 1982, Effects on rabbit nodal, atria, ventricular, and Purkinje cell potential of the new antiarrhythmic drug, cibenzoline, which protects against action potential shortening in hypoxia, British Journal of Pharmacology, 75, 469, 10.1111/j.1476-5381.1982.tb09163.x
Mitchell, 2005, Clonidine lowers blood pressure by reducing vascular resistance and cardiac output in young, healthy males, Cardiovascular Drugs and Therapy, 19, 49, 10.1007/s10557-005-6890-6
Montaigne, 2011, Doxorubicin induces mitochondrial permeability transition and contractile dysfunction in the human myocardium, Mitochondrion, 11, 22, 10.1016/j.mito.2010.06.001
Motomura, 1978, No evidence for involvement of dopaminergic receptors in the positive inotropic action of dopamine on the isolated rabbit papillary muscle, Japanese Journal of Pharmacology, 28, 145, 10.1254/jjp.28.145
Noguchi, 1998, In-vitro negative chronotropic and inotropic effects of a novel dihydropyridine derivative, CD-832, in the guinea-pig: Comparison with calcium-channel antagonists, Journal of Pharmacy and Pharmacology, 50, 329, 10.1111/j.2042-7158.1998.tb06869.x
Naruto, 2009, Assessment of the pharmacological effects of inotropic drugs on left ventricular pressure and contractility: An evaluation of the QA interval as an indirect indicator of cardiac ionotropism, Journal of Pharmacological and Toxicological Methods, 60, 193, 10.1016/j.vascn.2009.05.008
Orphanos, 2009, Cardiotoxicity induced by tyrosine kinase inhibitors, Acta Oncologica, 48, 964, 10.1080/02841860903229124
Packer, 1984, Hemodynamic and clinical limitations of long-term inotropic therapy with amrinone in patients with severe heart failure, Circulation, 70, 1038, 10.1161/01.CIR.70.6.1038
Packer, 1991, Effect of oral milrinone on mortality in chronic heart failure, New England Journal of Medicine, 325, 1468, 10.1056/NEJM199111213252103
Pollick, 1982, The cardiac effects of d- and l-disopyramide in normal subjects: A noninvasive study, Circulation, 66, 447, 10.1161/01.CIR.66.2.447
Qu, 2013, Itraconazole decreases left ventricular contractility in isolated rabbit heart: Mechanism of action, Toxicology and Applied Pharmacology, 268, 113, 10.1016/j.taap.2013.01.029
Riou, 1989, Inotropic effect of ketamine on rat cardiac papillary muscle, Anesthesiology, 71, 116, 10.1097/00000542-198907000-00020
Rothschild, 1989, The inotropic action of tolbutamide and glyburide, Clinical Pharmacology and Therapeutics, 45, 642, 10.1038/clpt.1989.85
Rump, 1994, A quantitative comparison of functional and anti-ischaemic effects of the phosphodiesterase-inhibitors, amrinone, milrinone and levosimendan in rabbit isolated hearts, British Journal of Pharmacology, 112, 757, 10.1111/j.1476-5381.1994.tb13143.x
Sanchez-Chapula, 1981, Multiple effects of putative α-adrenoceptor agonists on the electrical and mechanical activity of guinea-pig papillary muscle, Naunyn-Schmiedeberg's Archives of Pharmacology, 316, 108, 10.1007/BF00505302
Sartor, 1980, Serum glibenclamide in diabetic patients, and influence of food on the kinetics of glibenclamide, Diabetologia, 18, 17, 10.1007/BF01228296
Sato, 1994, Evaluation of a new method using telemetry for monitoring the left ventricular pressure in free-moving rats, Journal of Pharmacological and Toxicological Methods, 31, 191, 10.1016/1056-8719(94)90003-5
Sato, 1998, Effects of levosimendan on myocardial contractility and Ca2+ transients in aequorin-loaded right-ventricular papillary muscles and indo-1-loaded single ventricular cardiomyocytes of the rabbit, Journal of Molecular and Cellular Cardiology, 30, 1115, 10.1006/jmcc.1998.0677
Schulz, 2003, Therapeutic and toxic blood concentrations of more than 800 drugs and other xenobiotics, Pharmazie, 58, 447
Scott, 2014, An impedance-based cellular assay using human iPSC-derived cardiomyocytes to quantify modulators of cardiac contractility, Toxicol Sci, 142, 331, 10.1093/toxsci/kfu186
Seals, 1987, Antiarrhythmic efficacy and hemodynamic effects of cibenzoline in patients with nonsustained ventricular tachycardia and left ventricular dysfunction, Circulation, 75, 800, 10.1161/01.CIR.75.4.800
Semafuko, 1975, Papillary muscle dynamics: In situ function and responses of the papillary muscle, American Journal of Physiology, 228, 1800, 10.1152/ajplegacy.1975.228.6.1800
Shaid, 1989, Chronotropic and inotropic actions of milrinone, carbazeran and isobutylmethyl xanthine: Role of phosphodiesterase inhibition, British Journal of Pharmacology, 98, 291, 10.1111/j.1476-5381.1989.tb16894.x
Shaw, 1985, Plasma free captopril concentrations during short and long term treatment with oral captopril for heart failure, British Heart Journal, 54, 160, 10.1136/hrt.54.2.160
Shiels, 2008, The Frank–Starling mechanism in vertebrate cardiac myocytes, Journal of Experimental Biology, 211, 2005, 10.1242/jeb.003145
Siegel, 1984, Responses to amrinone in isolated cardiac muscles from cat, rabbit and guinea pig, Journal of Cardiovascular Pharmacology, 6, 281, 10.1097/00005344-198403000-00012
Singh, 1977, Effects of intravenous verapamil on hemodynamics in patients with heart disease, American Heart Journal, 94, 593, 10.1016/S0002-8703(77)80128-2
Skrzypiec-Spring, 2007, Isolated heart perfusion according to Langendorff — Still viable in the new millennium, Journal of Pharmacological and Toxicological Methods, 55, 113, 10.1016/j.vascn.2006.05.006
Sperelakis, 2001
Suga, 1973, Load independence of the instantaneous pressure–volume ratio of the canine left ventricle and effects of epinephrine and heart rate on the ratio, Circulation Research, 32, 314, 10.1161/01.RES.32.3.314
Sundberg, 1998, Integrated pharmacokinetics and pharmacodynamics of the novel calcium sensitizer levosimendan as assessed by systolic time intervals, International Journal of Clinical Pharmacology and Therapeutics, 36, 629
Syme, 1995, Influence of muscle length on work from trabecular muscle of frog atrium and ventricle, Journal of Experimental Biology, 198, 2221, 10.1242/jeb.198.10.2221
Tuttle, 1975, Dobutamine: Development of a new catecholamine to selectively increase cardiac contractility, Circulation Research, 36, 185, 10.1161/01.RES.36.1.185
Varma, 1999, Inverse agonist activities of b-adrenoceptor antagonists in rat myocardium, British Journal of Pharmacology, 127, 895, 10.1038/sj.bjp.0702616
Véniant, 1991, Ro-40-5967, in contrast to diltiazem, does not reduce left ventricular contractility in rats with chronic myocardial infarction, Journal of Cardiovascular Research, 17, 277
Williams, 1981, Effect of quinidine on positive inotropic action of digoxin, American Journal of Cardiology, 47, 1052, 10.1016/0002-9149(81)90211-3
Wing, 1997, Pharmacokinetic and concentration-effect relationships of clonidine in essential hypertension, European Journal of Clinical Pharmacology, 12, 463, 10.1007/BF00561067
Zausig, 2006, A comparison of three phosphodiesterase type II inhibitors on mechanical and metabolic function in the guinea pig isolated hearts, Anesthesia and Analgesia, 102, 1646, 10.1213/01.ane.0000216290.74626.27
Zimpfer, 1981, Effects of acute increases in left ventricular preload and indices of myocardial function in conscious, unrestrained and intact, tranquilized baboons, Journal of Clinical Investigation, 67, 430, 10.1172/JCI110051