Predictive value of cyclooxygenase 2 and Bcl-2 for cervical lymph node metastasis in mucoepidermoid carcinoma

Speight, 2002, Salivary gland tumors, Oral Dis, 8, 229, 10.1034/j.1601-0825.2002.02870.x Kusafuka, 2007, Primary nasopharyngeal mucoepidermoid carcinoma in Japanese patients: two case reports with histochemical and immunohistochemical analysis and a review of the literature, Virchows Arch, 450, 343, 10.1007/s00428-006-0277-3 Kuo TT, Chan JKC, Wenig BM, Eveson JW. Nasopharyngeal adenocarcinoma and salivary gland-type carcinoma. In: Barnes L, Eveson JW, Reichart P, Sidransky D (eds). World Health Organization classification tumours: pathology & genetics head and neck tumours. WHO Publications Center, Albany, NY, USA, IARC Press, Lyon, 2005;p 98. Shaheel Chummun, 2008, Mucoepidermoid carcinoma of the head and neck: a 13-year review, Eur J Plast Surg, 30, 277, 10.1007/s00238-007-0202-2 Goode, 1998, Mucoepidermoid carcinoma of the major salivary glands: clinical and histopathologic analysis of 234 cases with evaluation of grading criteria, Cancer, 82, 1217, 10.1002/(SICI)1097-0142(19980401)82:7<1217::AID-CNCR2>3.0.CO;2-C Brandwein, 2001, Mucoepidermoid carcinoma: a clinicopathologic study of 80 patients with special reference to histological grading, Am J Surg Pathol, 25, 835, 10.1097/00000478-200107000-00001 Bevilacqua, 1989, Association of low nm23 RNA levels in human primary infiltrating ductal breast carcinomas with lymph node involvement and other histopathological indicators of high metastatic potential, Cancer, 49, 5185 Bradley, 2001, Distant metastases from salivary glands cancer, ORL J Otorhinolaryngol Relat Spec, 63, 233, 10.1159/000055748 Ellis, 1996, 155 Kase, 2003, Expression of cyclo-oxygenase-2 is correlated with high intratumoral microvessel density and low apoptotic index in human esophageal squamous cell carcinomas, Virchows Arch, 442, 129, 10.1007/s00428-002-0706-x Fosslien, 2000, Biochemistry of cyclooxygenase (COX)-2 inhibitors and molecular pathology of COX-2 in neoplasia, Crit Rev Clin Lab Sci, 37, 431, 10.1080/10408360091174286 Farrow, 1998, Use of aspirin and other nonsteroidal anti-inflammatory drugs and risk of esophageal and gastric cancer, Cancer Epidemiol Biomarkers Prev, 7, 97 Reddy, 1987, Dose-related inhibition of colon carcinogenesis by dietarypiroxicam, a nonsteroidal anti-inflammatory drug during different stages of rat colon tumor development, Cancer Res, 47, 5340 Tsujii, 1998, Cyclooxygenase regulates angiogenesis induced by colon cancer cells, Cell, 93, 705, 10.1016/S0092-8674(00)81433-6 Attiga, 2000, Inhibitors of prostaglandin synthesis inhibit human prostate tumor cell invasiveness and reduce the release of matrix metalloproteinases, Cancer Res, 60, 4629 Tsujii, 1995, Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2, Cell, 83, 493, 10.1016/0092-8674(95)90127-2 Tsujii, 1997, Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential, Proc Natl Acad Sci U S A, 94, 3336, 10.1073/pnas.94.7.3336 Wang, 1993, Wild type p53 triggered apoptosis is inhibited by bcl-2 in v-myc induced T-cell lymphoma lines, Oncogene, 8, 3427 Johnson, 1998, Apoptosis regulating genes in prostate cancer, Oncol Rep, 5, 553 Vairo, 1996, BCL-2 has a cycle inhibitory function separable from its enhancement of cell survival, Oncogene, 13, 1511 Sakamoto, 2005, Cyclooxygenase-2 regulates the degree of apoptosis by modulating bcl-2 protein in pleomorphic adenoma and mucoepidermoid carcinoma of the parotid gland, Act Oto-Laryngologica, 125, 191, 10.1080/00016480410017693 2005, 313 Wittenkind, 2004, 5 Hsu, 1981, Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques a comparison between ABC and unlabeled antibody PAP procedures, J Histochem Cytochem, 29, 577, 10.1177/29.4.6166661 Segawa, 2008, Expression of cyclooxygenase-2 and DNA topoisomerase II in precancerous and cancerous lesions of the oral mucosa, Oral Oncol, 44, 664, 10.1016/j.oraloncology.2007.08.014 Ozawa, 2008, Mucoepidermoid carcinoma of the head and neck: clinical analysis of 43 patients, Jpn J Clin Oncol, 38, 414, 10.1093/jjco/hyn045 Spiro, 1978, Mucoepidermoid carcinoma of salivary glands: a clinicopathologic study of 367 cases, Am J Surg, 136, 461, 10.1016/0002-9610(78)90262-3 Suzuki, 1998, Histological features and prognosis of patients with mucoepidermoid carcinoma of the parotid gland, J Laryngol Otol, 112, 944, 10.1017/S0022215100142148 Evans, 1984, Mucoepidermoid carcinoma of salivary glands. a study of 69 cases with special attention to histologic grading, Am J Clin Pathol, 81, 696, 10.1093/ajcp/81.6.696 Kaklamanis, 1996, Early expression of BCL-2 protein in the adenoma-carcinoma sequence of colorectal neoplasia, J Pathol, 179, 10, 10.1002/(SICI)1096-9896(199605)179:1<10::AID-PATH540>3.0.CO;2-1 Friess, 1998, Bax, but not bcl-2, influences the prognosis of human pancreatic cancer, Gut, 43, 414, 10.1136/gut.43.3.414 Hu, 1999, BCL-2 expression related to altered p53 protein and its impact on the progression of human pancreatic carcinoma, Br J Cancer, 80, 1075, 10.1038/sj.bjc.6690466 Eid, 1998, Expression of BCL-2 in testicular carcinoma, Cancer, 83, 331, 10.1002/(SICI)1097-0142(19980715)83:2<331::AID-CNCR17>3.0.CO;2-U Rochaix, 1999, In vivo patterns of BCL-2 family protein expression in breast carcinoma in relation to apoptosis, J Pathol, 187, 410, 10.1002/(SICI)1096-9896(199903)187:4<410::AID-PATH266>3.0.CO;2-F Itoh, 2003, Immunohistochemical study on overexpression of cyclooxgenase-2 in squamous cell carcinoma of the oral cavity: its importance as a prognostic predictor, Oral Oncol, 39, 829, 10.1016/S1368-8375(03)00105-2 Yanez, 1999, BCL-2 gene protein expression in salivary gland tumors, Rev Med Chil, 127, 139 Yoshikawa, 2000, Expression of cyclooxygenase-2 in prostate carcinoma, Cancer, 89, 589, 10.1002/1097-0142(20000801)89:3<589::AID-CNCR14>3.0.CO;2-C Peng, 2002, Overexpression of cyclooxygenase 2 in squamous cell carcinoma of the hypopharynx, Hum Pathol, 33, 101, 10.1053/hupa.2002.30187 Zimmermann, 1999, Cyclooxygenase-2 expression in human esophageal carcinoma, Cancer Res, 59, 198 Huang, 1998, Non-small cell lung cancer cyclooxygenase-2 dependent regulation of cytokine balance in lymphocytes and macrophage: up-regulation of interleukin 10 and down-regulation of interleukin 12 production, Cancer Res, 58, 1208 Yin, 2000, Apoptosis and apoptotic-related factors in mucoepidermoid carcinoma of the minor salivary glands, Pathol Int, 50, 603, 10.1046/j.1440-1827.2000.01091.x Siziopikou, 1996, BCL-2 expression in the spectrum of preinvasive breast lesions, Cancer, 77, 499, 10.1002/(SICI)1097-0142(19960201)77:3<499::AID-CNCR11>3.0.CO;2-# Yang, 2003, Prognostic value of BCL-2 in invasive breast cancer receiving chemotherapy and endocrine therapy, Oncol Rep, 10, 121 Shibata, 2005, Cyclo-oxygenase-1 and 2-expression in human oral mucosa, dysplasia and squamous cell carcinomas and their pathological significance, Oral Oncol, 41, 304, 10.1016/j.oraloncology.2004.09.009 Tsubochi, 2006, Combined analysis of cyclooxygenase-2 expression with p35 and ki-67 in non small cell lung cancer, Ann Thorac Surg, 82, 1198, 10.1016/j.athoracsur.2006.04.069 Smith, 2000, The effect of nonsteroidal anti-inflammatory drugs on human colorectal cancer cells: evidence of different mechanisms of action, Eur J Cancer, 36, 664, 10.1016/S0959-8049(99)00333-0 Watson, 1998, Chemopreventive effects of NSAIDs against colorectal cancer: regulation of apoptosis and mitosis by COX-1 and -2, Histol Histopathol, 13, 591