Preclinical studies and prospective clinical applications for bacteria-targeted imaging: the future is bright
Tóm tắt
Từ khóa
Tài liệu tham khảo
Love C, Palestro CJ (2004) Radionuclide imaging of infection. J Nucl Med Technol 32(2):47–57
Laxminarayan R, Duse A, Wattal C, Zaidi AK, Wertheim HF, Sumpradit N et al (2013) Antibiotic resistance—the need for global solutions. Lancet Infect Dis 13(12):1057–1098
World Health Organization (2016) The evolving threat of antimicrobial resistance—options for action. http://apps.who.int/iris/bitstream/10665/44812/1/9789241503181_eng.pdf . Accessed 25 February 2016
Parvizi J, Pawasarat IM, Azzam KA, Joshi A, Hansen EN, Bozic KJ (2010) Periprosthetic joint infection: the economic impact of methicillin-resistant infections. J Arthroplasty 25(6 Suppl):103–107
Sabat AJ, Budimir A, Nashev D, Sa-Leao R, van Dijl J, Laurent F et al (2013) Overview of molecular typing methods for outbreak detection and epidemiological surveillance. Euro Surveill 18(4):20380
Carek PJ, Dickerson LM, Sack JL (2001) Diagnosis and management of osteomyelitis. Am Fam Physician 63(12):2413–2420
Hatzenbuehler J, Pulling TJ (2011) Diagnosis and management of osteomyelitis. Am Fam Physician 84(9):1027–1033
Trampuz A, Zimmerli W (2006) Diagnosis and treatment of infections associated with fracture-fixation devices. Injury 37(Suppl 2):S59–S66
van Oosten M, Hahn M, Crane LM, Pleijhuis RG, Francis KP, van Dijl JM et al (2015) Targeted imaging of bacterial infections: advances, hurdles and hopes. FEMS Microbiol Rev 39(6):892–916
Love C, Tomas MB, Tronco GG, Palestro CJ (2005) FDG PET of infection and inflammation. Radiographics 25(5):1357–1368
Mills B, Bradley M, Dhaliwal K (2016) Optical imaging of bacterial infections. Clin Transl Imaging 4:163–174. doi: 10.1007/s40336-016-0180-0
El-Haddad G, Zhuang H, Gupta N, Alavi A (2004) Evolving role of positron emission tomography in the management of patients with inflammatory and other benign disorders. Semin Nucl Med 34(4):313–329
Glaudemans AW, Galli F, Pacilio M, Signore A (2013) Leukocyte and bacteria imaging in prosthetic joint infection. Eur Cell Mater 25:61–77
Fogarasi M, Pullman J, Winnard P Jr, Hnatowich DJ, Rusckowski M (1999) Pretargeting of bacterial endocarditis in rats with streptavidin and 111In-labeled biotin. J Nucl Med 40(3):484–490
Lazzeri E, Pauwels EK, Erba PA, Volterrani D, Manca M, Bodei L et al (2004) Clinical feasibility of two-step streptavidin/111In-biotin scintigraphy in patients with suspected vertebral osteomyelitis. Eur J Nucl Med Mol Imaging 31(11):1505–1511
Britton KE, Wareham DW, Das SS, Solanki KK, Amaral H, Bhatnagar A et al (2002) Imaging bacterial infection with 99mTc-ciprofloxacin (Infecton®). J Clin Pathol 55(11):817–823
Sarda L, Crémieux AC, Lebellec Y, Meulemans A, Lebtahi R, Hayem G et al (2003) Inability of 99mTc-ciprofloxacin scintigraphy to discriminate between septic and sterile osteoarticular diseases. J Nucl Med 44(6):920–926
Siaens RH, Rennen HJ, Boerman OC, Dierckx R, Slegers G (2004) Synthesis and comparison of 99mTc-enrofloxacin and 99mTc-ciprofloxacin. J Nucl Med 45(12):2088–2094
Dumarey N, Blocklet D, Appelboom T, Tant L, Schoutens A (2002) Infection is not specific for bacterial osteo-articular infective pathology. Eur J Nucl Med Mol Imaging 29(4):530–535
Langer O, Brunner M, Zeitlinger M, Zielger S, Müller U, Dobrozemsky G et al (2004) In vitro and in vivo evaluation of [18F]ciprofloxacin for the imaging of bacterial infections with PET. Eur J Nucl Med Mol Imaging 32(2):143–150
Hall AV, Solanki KK, Vinjamuri S, Britton KE, Das SS (1998) Evaluation of the efficacy of 99mTc-Infecton, a novel agent for detecting sites of infection. J Clin Pathol 51(3):215–219
Malamitsi J, Giamarellou H, Kanellakopoulou K, Dounis E, Grecka V, Christakopoulos J et al (2003) Infecton®: a 99mTc-ciprofloxacin radiopharmaceutical for the detection of bone infection. Clin Microbiol Infect 9(2):101–109
Kaul A, Hazari PP, Rawat H, Singh B, Kalawat TC, Sharma S et al (2013) Preliminary evaluation of Technetium-99m-labeled ceftriaxone: infection imaging agent for the clinical diagnosis of orthopedic infection. Int J Infect Dis 17(4):263–270
Fischman AJ, Livni E, Babich JW, Alpert NM, Bonab A, Chodosh S et al (1996) Pharmacokinetics of [18F]fleroxacin in patients with acute exacerbations of chronic bronchitis and complicated urinary tract infection studied by positron emission tomography. Antimicrob Agents Chemother 40(3):659–664
Assadi M, Vahdat K, Nabipour I, Sehhat MR, Hadavand F, Javadi H et al (2011) Diagnostic value of 99mTc-ubiquicidin scintigraphy for osteomyelitis and comparisons with 99mTc-methylene diphosphonate scintigraphy and magnetic resonance imaging. Nucl Med Commun 32(8):716–723
Akhtar MS, Qaisar A, Irfanullah J, Iqbal J, Khan B, Jehangir M et al (2005) Antimicrobial peptide 99mTc-ubiquicidin 29–41 as human infection-imaging agent: clinical trial. J Nucl Med 46(4):567–573
Melendez-Alafort L, Rodriguez-Cortes J, Ferro-Flores G, Arteaga De Murphy C, Herrera-Rodriguez R, Mitsoura E et al (2004) Biokinetics of (99m)Tc-UBI 29-41 in humans. Nucl Med Biol 31(3):373–379
Gandomkar M, Najafi R, Shafiei M, Mazidi M, Goudarzi M, Mirfallah SH et al (2009) Clinical evaluation of antimicrobial peptide [(99m)Tc/Tricine/HYNIC(0)]ubiquicidin 29–41 as a human-specific infection imaging agent. Nucl Med Biol 36(2):199–205
Ostovar A, Mahsan Assadi M, Vahdat K, Nabipour I, Javadi H, Eftekhari M et al (2013) A pooled analysis of diagnostic value of 99mTc-ubiquicidin (UBI) scintigraphy in detection of an infectious process. Clin Nucl Med 38(6):413–416
Diaz LA Jr, Foss CA, Thornton K, Nimmagadda S, Endres CJ, Uzuner O et al (2007) Imaging of musculoskeletal bacterial infections by [124I]FIAU-PET/CT. PLoS One 2(10):e1007
Zhang XM, Zhang HH, McLeroth P, Berkowitz RD, Mont MA, Stabin MG et al (2016) [124I]FIAU: human dosimetry and infection imaging in patients with suspected prosthetic joint infection. Nucl Med Biol 43(5):273–279
Nijhof MW, Oyen WJ, van Kampen A, Claessens RA, van der Meer JW, Corstens FH (1997) Evaluation of infections of the locomotor system with indium-111-labeled human IgG scintigraphy. J Nucl Med 38(8):1300–1305
Buscombe JR, Oyen WJ, Grant A, Claessens RA, van der Meer J, Corstens FH et al (1993) Indium-111-labeled polyclonal human immunoglobulin: identifying focal infection in patients positive for human immunodeficiency virus. J Nucl Med 34(10):1621–1625
Buscombe JR, Oyen WJ, Corstens FH, Ell PJ, Miller RF (1995) A comparison of 111In-HIG scintigraphy and chest radiology in the identification of pulmonary infection in patients with HIV infection. Nucl Med Commun 16(5):327–335
Gowrishankar G, Namavari M, Jouannot EB, Hoehne A, Reeves R, Hardy J et al (2014) Investigation of 6-[18F]-fluoromaltose as a novel PET tracer for imaging bacterial infection. PLoS One 9(9):e107951
Weinstein EA, Ordonez AA, DeMarco VP, Murawski AM, Pokkali S, MacDonald EM et al (2014) Imaging Enterobacteriaceae infection in vivo with 18F-fluorodeoxysorbitol positron emission tomography. Sci Transl Med 6(259):259ra146
van Oosten M, Schafer T, Gazendam JA, Ohlsen K, Tsompanidou E, de Goffau MC et al (2013) Real-time in vivo imaging of invasive- and biomaterial-associated bacterial infections using fluorescently labelled vancomycin. Nat Commun 4:2584
Luo S, Zhang E, Su Y, Cheng T, Shi C (2011) A review of NIR dyes in cancer targeting and imaging. Biomaterials 32(29):7127–7138
Hellebust A, Richards-Kortum R (2012) Advances in molecular imaging: targeted optical contrast agents for cancer diagnostics. Nanomedicine (Lond) 7(3):429–445
Pleijhuis RG, Langhout GC, Helfrich W, Themelis G, Sarantopoulos A, Crane LM et al (2011) Near-infrared fluorescence (NIRF) imaging in breast-conserving surgery: assessing intraoperative techniques in tissue-simulating breast phantoms. Eur J Surg Oncol 37(1):32–39
Witjes JA, Redorta JP, Jacqmin D, Sofras F, Malmstrom PU, Riedl C et al (2010) Hexaminolevulinate-guided fluorescence cystoscopy in the diagnosis and follow-up of patients with non-muscle-invasive bladder cancer: review of the evidence and recommendations. Eur Urol 57(4):607–614
Colditz MJ, Jeffree RL (2012) Aminolevulinic acid (ALA)-protoporphyrin IX fluorescence guided tumour resection. Part 1: clinical, radiological and pathological studies. J Clin Neurosci 19(11):1471–1474
Vahrmeijer AL, Hutteman M, van der Vorst JR, van de Velde CJ, Frangioni JV (2013) Image-guided cancer surgery using near-infrared fluorescence. Nat Rev Clin Oncol 10(9):507–518
van Dam GM, Themelis G, Crane LM, Harlaar NJ, Pleijhuis RG, Kelder W et al (2011) Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-alpha targeting: first in-human results. Nat Med 17(10):1315–1319
Ning X, Lee S, Wang Z, Kim D, Stubblefield B, Gilbert E et al (2011) Maltodextrin-based imaging probes detect bacteria in vivo with high sensitivity and specificity. Nat Mater 10(8):602–607
Panizzi P, Nahrendorf M, Figueiredo JL, Panizzi J, Marinelli B, Iwamoto Y et al (2011) In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation. Nat Med 17(9):1142–1146
Leevy WM, Gammon ST, Johnson JR, Lampkins AJ, Jiang H, Marquez M et al (2008) Noninvasive optical imaging of Staphylococcus aureus bacterial infection in living mice using a Bis-dipicolylamine-zinc(II) affinity group conjugated to a near-infrared fluorophore. Bioconjug Chem 19(3):686–692
Thakur ML, Zhang K, Paudyal B, Devakumar D, Covarrubias MY, Chen CP et al (2012) Targeting apoptosis for optical imaging of infection. Mol Imaging Biol 14(2):163–171
Ntziachristos V, Razansky D (2010) Molecular imaging by means of multispectral optoacoustic tomography (MSOT). Chem Rev 110(5):2783–2794
Ntziachristos V (2010) Going deeper than microscopy: the optical imaging frontier in biology. Nat Methods 7(8):603–614
Tan M, Wu X, Jeong EK, Chen Q, Parker DL, Lu ZR (2010) An effective targeted nanoglobular manganese(II) chelate conjugate for magnetic resonance molecular imaging of tumor extracellular matrix. Mol Pharm 7(4):936–943
Reuveni T, Motiei M, Romman Z, Popovtzer A, Popovtzer R (2011) Targeted gold nanoparticles enable molecular CT imaging of cancer: an in vivo study. Int J Nanomedicine 6:2859–2864
Anastasiadis P, Mojica KD, Allen JS, Matter ML (2014) Detection and quantification of bacterial biofilms combining high-frequency acoustic microscopy and targeted lipid microparticles. J Nanobiotechnol 12:24
Elias DR, Thorek DL, Chen AK, Czupryna J, Tsourkas A (2008) In vivo imaging of cancer biomarkers using activatable molecular probes. Cancer Biomark 4(6):287–305
Kong Y, Yao H, Ren H, Subbian S, Cirillo SL, Sacchettini JC et al (2010) Imaging tuberculosis with endogenous beta-lactamase reporter enzyme fluorescence in live mice. Proc Natl Acad Sci USA 107(27):12239–12244
Hernandez FJ, Huang L, Olson ME, Powers KM, Hernandez LI, Meyerholz DK et al (2014) Noninvasive imaging of Staphylococcus aureus infections with a nuclease-activated probe. Nat Med 20(3):301–306
Lee S, Chen X (2009) Dual-modality probes for in vivo molecular imaging. Mol Imaging 8(2):87–100
Azhdarinia A, Ghosh P, Ghosh S, Wilganowski N, Sevick-Muraca EM (2012) Dual-labeling strategies for nuclear and fluorescence molecular imaging: a review and analysis. Mol Imaging Biol 14(3):261–276
Welling MM, Bunschoten A, Kuil J, Nelissen RG, Beekman FJ, Buckle T et al (2015) Development of a hybrid tracer for SPECT and optical imaging of bacterial infections. Bioconjug Chem 26(5):839–849
Rajesh S, Koshi E, Philip K, Mohan A (2011) Antimicrobial photodynamic therapy: an overview. J Indian Soc Periodontol 15(4):323–327
Mitsunaga M, Ogawa M, Kosaka N, Rosenblum LT, Choyke PL, Kobayashi H (2011) Cancer cell-selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules. Nat Med 17(12):1685–1691
Kharkwal GB, Sharma SK, Huang YY, Dai T, Hamblin MR (2011) Photodynamic therapy for infections: clinical applications. Lasers Surg Med 43(7):755–767
Mitsunaga M, Nakajima T, Sano K, Kramer-Marek G, Choyke PL, Kobayashi H (2012) Immediate in vivo targetspecific cancer cell death after near infrared photoimmunotherapy. BMC Cancer 12:345
Ragas X, Sanchez-Garcia D, Ruiz-Gonza lez R, Dai T, Agut M, MR Hamblin, Nonell S (2010) Cationic porphycenes as potential photosensitizers for antimicrobial photodynamic therapy. J Med Chem 53(21):7796–7803
Bhatti M, MacRobert A, Henderson B, Shepherd P, Cridland J, Wilson M (2000) Antibody-targeted lethal photosensitization of Porphyromonas gingivalis. Antimicrob Agents Chemother 44(10):2615–2618
Demidova TN, Hamblin MR (2004) Photodynamic therapy targeted to pathogens. Int J Immunopathol Pharmacol 17(3):245–254
Dosselli R, Tampieri C, Ruiz-Gonzalez R, De Munari S, Ragas X, Sanchez-Garcia D et al (2013) Synthesis, characterization, and photoinduced antibacterial activity of porphyrin-type photosensitizers conjugated to the antimicrobial peptide apidaecin 1b. J Med Chem 56(3):1052–1063
Suci P, Kang S, Gmur R, Douglas T, Young M (2010) Targeted delivery of a photosensitizer to Aggregatibacter actinomycetemcomitans biofilm. Antimicrob Agents Chemother 54(6):2489–2496
Terwisscha van Scheltinga AG, van Dam GM, Nagengast WB, Ntziachristos V, Hollema H, Herek JL et al (2011) Intraoperative near-infrared fluorescence tumor imaging with vascular endothelial growth factor and human epidermal growth factor receptor 2 targeting antibodies. J Nucl Med 52(11):1778–1785
Murdoch DR, Corey GR, Hoen B, Miro JM, Fowler VG Jr, Bayer AS et al (2009) Clinical presentation, etiology, and outcome of infective endocarditis in the 21st century: the international collaboration on endocarditis-prospective cohort study. Arch Intern Med 169(5):463–473
Li JS, Sexton DJ, Mick N, Nettles R, Fowler VG Jr, Ryan T et al (2000) Proposed modifications to the Duke criteria for the diagnosis of infective endocarditis. Clin Infect Dis 30(4):633–638
Habets J, Tanis W, van Herwerden LA, van den Brink RB, Mali WP, de Mol BA et al (2014) Cardiac computed tomography angiography results in diagnostic and therapeutic change in prosthetic heart valve endocarditis. Int J Cardiovasc Imaging 30(2):377–387
Habib G, Lancellotti P, Antunes MJ, Bongiorni MG, Casalta JP, Del Zotti F et al (2015) 2015 ESC Guidelines for the management of infective endocarditis: the task force for the management of infective endocarditis of the european society of cardiology (esc) endorsed by: European Association for Cardio-Thoracic Surgery (EACTS), the European Association of Nuclear Medicine (EANM). Eur Heart J 36(44):3075–3128
Gomes A, Glaudemans AWJM, Touw DJ, van Melle JP, Willems TP, Maass AH et al (2016) Diagnostic value of imaging in infective endocarditis: a systematic literature review and a proposal of an updated diagnostic work-up. Lancet Infect Dis (in press)
Pizzi MN, Roque A, Fernandez-Hidalgo N, Cuellar-Calabria H, Ferreira-Gonzalez I, Gonzalez-Alujas MT et al (2015) Improving the diagnosis of infective endocarditis in prosthetic valves and intracardiac devices with 18F-fluordeoxyglucose positron emission tomography/computed tomography angiography: initial results at an infective endocarditis referral center. Circulation 132(12):1113–1126
Rouzet F, Chequer R, Benali K, Lepage L, Ghodbane W, Duval X et al (2014) Respective performance of 18F-FDG PET and radiolabeled leukocyte scintigraphy for the diagnosis of prosthetic valve endocarditis. J Nucl Med 55(12):1980–1985
Fukuchi K, Ishida Y, Higashi M, Tsunekawa T, Ogino H, Minatoya K et al (2005) Detection of aortic graft infection by fluorodeoxyglucose positron emission tomography: comparison with computed tomographic findings. J Vasc Surg 42(5):919–925
Keidar Z, Pirmisashvili N, Leiderman M, Nitecki S, Israel O (2014) 18F-FDG uptake in noninfected prosthetic vascular grafts: incidence, patterns, and changes over time. J Nucl Med 55(3):392–395
Bruggink JL, Slart RH, Pol JA, Reijnen MM, Zeebregts CJ (2011) Current role of imaging in diagnosing aortic graft infections. Semin Vasc Surg 24(4):182–190
Erba PA, Leo G, Sollini M, Tascini C, Boni R, Berchiolli RN et al (2014) Radiolabelled leucocyte scintigraphy versus conventional radiological imaging for the management of late, low-grade vascular prosthesis infections. Eur J Nucl Med Mol Imaging 41(2):357–368
Iovino F, Seinen J, Henriques-Normark B, van Dijl JM (2016) How does Streptococcus pneumoniae invade the brain? Trends Microbiol 24(4):307–315
Nensa F, Beiderwellen K, Heusch P, Wetter A (2014) Clinical applications of PET/MRI: current status and future perspectives. Diagn Interv Radiol 20(5):438–447
Yang ZL, Zhang LJ (2016) PET/MRI of central nervous system: current status and future perspective. Eur Radiol. doi: 10.1007/s00330-015-4202-5
Beyer T, Freudenberg LS, Czernin J, Townsend DW (2011) The future of hybrid imaging-part 3: PET/MR, small-animal imaging and beyond. Insights Imaging 2(3):235–246
Fàbregas N, Ewig S, Torres A, El-Ebiary M, Ramirez J, de La Bellacasa JP et al (1999) Clinical diagnosis of ventilator associated pneumonia revisited: comparative validation using immediate postmortem lung biopsies. Thorax 54(10):867–873