Preclinical cardiac safety assessment of pharmaceutical compounds using an integrated systems-based computer model of the heart

Progress in Biophysics and Molecular Biology - Tập 90 - Trang 414-443 - 2006
Dean Bottino1, R. Christian Penland2, Andrew Stamps3, Martin Traebert4, Bérengère Dumotier4, Anna Georgieva5, Gabriel Helmlinger6, G. Scott Lett1
1The BioAnalytics Group LLC, USA
2Predix Pharmaceuticals, USA
3Department of Chemical Engineering, University of South Carolina, USA
4Safety Profiling & Assessment, Novartis Pharma AG, Basel, Switzerland
5Modeling & Simulation, Novartis Pharmaceuticals, East Hanover, USA
6Modeling & Simulation, Novartis Institutes for Biomedical Research Inc., Cambridge, USA

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Progress in Biophysics and Molecular Biology

Tập 90

414-443

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