Potentiation of oxytetracycline antimicrobial activity in vivo by concurrent administration of bromhexine

International Journal of Pharmaceutics - Tập 43 - Trang 77-81 - 1988
Jaspal S. Malhi1, Anita-Jane High1, Geoffrey W. Hanlon1, Paul R. Gard1, Christopher Marriott1
1Pharmaceutical Sciences Research Group, Department of Pharmacy, Brighton Polytechnic, BrightonU.K.

Tài liệu tham khảo

Abdou, 1975, Observations on the increase in the oxytetracycline level in the bronchial mucosa of pigs when using a simultaneous dosage with bromhexine, Tierarztl. Umschau, 30, 565

Bach, 1972, The effect of bromhexine on the penetrance of oxytetracycline into sputum, S. Afr. Med. J., 46, 1512

Brown, 1983, Antibiotic binding to purified mucus glycoproteins, J. Pharm. Pharmacol., 35, 80P

Burgi, 1971, Changes in sputum fibre systems and viscosity during treatment with bromhexine, Clin. Trials J., 8, 37

Cowan, 1974, Characters and characteristics, 42

Kearney, 1987, The effects of mucus glycoprotein on the availability of tetracycline. II, Binding. Int. J. Pharm., 35, 211, 10.1016/0378-5173(87)90132-3

Kotzian, 1976, Increase in oxytetracycline level in the bronchial mucus following simultaneous administration of Bisolvon, Tierarztl. Umschau, 32Jg, 132

Malhi, 1986, The effect of oral mucolytic agents on the microflora of guinea pig uteri, J. Pharm. Pharmacol, 38, 38P, 10.1111/j.2042-7158.1986.tb14267.x

Marriott, 1975, The effect of tetracyclines on the viscoelastic properties of bronchial mucus, Biorheology, 12, 391, 10.3233/BIR-1975-12610

Turner, 1985, The influence of native porcine gastric mucus gel on hydrogen ion diffusion, J. Pharm. Pharmacol, 37, 776, 10.1111/j.2042-7158.1985.tb04967.x