Potential effector and immunoregulatory functions of mast cells in mucosal immunity
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Mekori, 2000, Mast cells in innate immunity, Immunol. Rev, 173, 131, 10.1034/j.1600-065X.2000.917305.x
Metz, 2007, Mast cells in the promotion and limitation of chronic inflammation, Immunol. Rev, 217, 304, 10.1111/j.1600-065X.2007.00520.x
Galli, 2008, Immunomodulatory mast cells: negative, as well as positive, regulators of immunity, Nat. Rev. Immunol, 8, 478, 10.1038/nri2327
Moon, 2010, Advances in mast cell biology: new understanding of heterogeneity and function, Mucosal Immunol, 3, 111, 10.1038/mi.2009.136
Gurish, 2012, Developmental origin and functional specialization of mast cell subsets, Immunity, 37, 25, 10.1016/j.immuni.2012.07.003
Galli, 2005, Mast cells in the development of adaptive immune responses, Nat. Immunol, 6, 135, 10.1038/ni1158
Galli, 2005, Mast cells as “tunable” effector and immunoregulatory cells: recent advances, Annu. Rev. Immunol, 23, 749, 10.1146/annurev.immunol.21.120601.141025
Kitamura, 1977, Development of mast cells from grafted bone marrow cells in irradiated mice, Nature, 268, 442, 10.1038/268442a0
Kitamura, 1989, Heterogeneity of mast cells and phenotypic change between subpopulations, Annu. Rev. Immunol, 7, 59, 10.1146/annurev.iy.07.040189.000423
Douaiher, 2014, Development of mast cells and importance of their tryptase and chymase serine proteases in inflammation and wound healing, Adv. Immunol, 122, 211, 10.1016/B978-0-12-800267-4.00006-7
Oliveira, 2003, Stem cell factor: a hemopoietic cytokine with important targets in asthma, Curr. Drug Targets Inflamm. Allergy, 2, 313, 10.2174/1568010033483990
Reber, 2006, Stem cell factor and its receptor c-Kit as targets for inflammatory diseases, Eur. J. Pharmacol, 533, 327, 10.1016/j.ejphar.2005.12.067
Galli, 1994, The kit ligand, stem cell factor, Adv. Immunol, 55, 1
Razin, 1984, Interleukin 3: a differentiation and growth factor for the mouse mast cell that contains chondroitin sulfate E proteoglycan, J. Immunol, 132, 1479, 10.4049/jimmunol.132.3.1479
Toru, 1996, Induction of the high-affinity IgE receptor (FcɛRI) on human mast cells by IL-4, Int. Immunol, 8, 1367, 10.1093/intimm/8.9.1367
Valent, 1991, Interleukin 4 promotes expression of mast cell ICAM-1 antigen, Proc. Natl. Acad. Sci. USA, 88, 3339, 10.1073/pnas.88.8.3339
Sillaber, 1991, IL-4 regulates c-kit proto-oncogene product expression in human mast and myeloid progenitor cells, J. Immunol, 147, 4224, 10.4049/jimmunol.147.12.4224
Toru, 1998, Interleukin-4 promotes the development of tryptase and chymase double-positive human mast cells accompanied by cell maturation, Blood, 91, 187, 10.1182/blood.V91.1.187
Matsuzawa, 2003, IL-9 enhances the growth of human mast cell progenitors under stimulation with stem cell factor, J. Immunol, 170, 3461, 10.4049/jimmunol.170.7.3461
Mwamtemi, 2001, An increase in circulating mast cell colony-forming cells in asthma, J. Immunol, 166, 4672, 10.4049/jimmunol.166.7.4672
Bailey, 2006, Interleukin-10 induces apoptosis in developing mast cells and macrophages, J. Leukoc. Biol, 80, 581, 10.1189/jlb.0405201
Royer, 2001, Inhibition of IgE-induced activation of human mast cells by IL-10, Clin. Exp. Allergy, 31, 694, 10.1046/j.1365-2222.2001.01069.x
Yeatman, 2000, Combined stimulation with the T helper cell type 2 cytokines interleukin (IL)-4 and IL-10 induces mouse mast cell apoptosis, J. Exp. Med, 192, 1093, 10.1084/jem.192.8.1093
Ho, 2007, IL-33 induces IL-13 production by mouse mast cells independently of IgE-FcɛRI signals, J. Leukoc. Biol, 82, 1481, 10.1189/jlb.0407200
Iikura, 2007, IL-33 can promote survival, adhesion and cytokine production in human mast cells, Lab. Invest, 87, 971, 10.1038/labinvest.3700663
Allakhverdi, 2007, Cutting edge: the ST2 ligand IL-33 potently activates and drives maturation of human mast cells, J. Immunol, 179, 2051, 10.4049/jimmunol.179.4.2051
Lin, 2000, Human mast cells transmigrate through human umbilical vein endothelial monolayers and selectively produce IL-8 in response to stromal cell-derived factor-1α, J. Immunol, 165, 211, 10.4049/jimmunol.165.1.211
Godot, 2007, H4 histamine receptor mediates optimal migration of mast cell precursors to CXCL12, J. Allergy Clin. Immunol, 120, 827, 10.1016/j.jaci.2007.05.046
Macey, 2010, IL-4 and TGF-β1 counterbalance one another while regulating mast cell homeostasis, J. Immunol, 184, 4688, 10.4049/jimmunol.0903477
Matsuda, 1991, Nerve growth factor induces development of connective tissue-type mast cells in vitro from murine bone marrow cells, J. Exp. Med, 174, 7, 10.1084/jem.174.1.7
Ruitenberg, 1976, Absence of intestinal mast cell response in congenitally athymic mice during Trichinella spiralis infection, Nature, 264, 258, 10.1038/264258a0
Friend, 1996, Mast cells that reside at different locations in the jejunum of mice infected with Trichinella spiralis exhibit sequential changes in their granule ultrastructure and chymase phenotype, J. Cell Biol, 135, 279, 10.1083/jcb.135.1.279
Friend, 1998, Reversible expression of tryptases and chymases in the jejunal mast cells of mice infected with Trichinella spiralis, J. Immunol, 160, 5537, 10.4049/jimmunol.160.11.5537
Hunt, 1996, Natural disruption of the mouse mast cell protease 7 gene in the C57BL/6 mouse, J. Biol. Chem, 271, 2851, 10.1074/jbc.271.5.2851
Jippo, 2001, Tissue-dependent alteration of protease expression phenotype in murine peritoneal mast cells that were genetically labeled with green fluorescent protein, Am. J. Pathol, 158, 1695, 10.1016/S0002-9440(10)64125-9
Galli, 2011, Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils, Nat. Immunol, 12, 1035, 10.1038/ni.2109
Irani, 1989, Detection of MCT and MCTC types of human mast cells by immunohistochemistry using new monoclonal anti-tryptase and anti-chymase antibodies, J. Histochem. Cytochem, 37, 1509, 10.1177/37.10.2674273
Li, 1996, Mast cells expressing chymase but not tryptase can be derived by culturing human progenitors in conditioned medium obtained from a human mastocytosis cell strain with c-kit ligand, J. Immunol, 156, 4839, 10.4049/jimmunol.156.12.4839
Weidner, 1993, Heterogeneity of mast cells at multiple body sites. Fluorescent determination of avidin binding and immunofluorescent determination of chymase, tryptase, and carboxypeptidase content, Pathol. Res. Pract, 189, 156, 10.1016/S0344-0338(11)80086-5
Irani, 1987, Deficiency of the tryptase-positive, chymase-negative mast cell type in gastrointestinal mucosa of patients with defective T lymphocyte function, J. Immunol, 138, 4381, 10.4049/jimmunol.138.12.4381
Irani, 1986, Two types of human mast cells that have distinct neutral protease compositions, Proc. Natl. Acad. Sci. USA, 83, 4464, 10.1073/pnas.83.12.4464
Matin, 1992, Distribution of chymase-containing mast cells in human bronchi, J. Histochem. Cytochem, 40, 781, 10.1177/40.6.1588024
Bischoff, 2009, Physiological and pathophysiological functions of intestinal mast cells, Semin. Immunopathol, 31, 185, 10.1007/s00281-009-0165-4
Bischoff, 1996, Quantitative assessment of intestinal eosinophils and mast cells in inflammatory bowel disease, Histopathology, 28, 1, 10.1046/j.1365-2559.1996.262309.x
Raithel, 2001, Release of mast cell tryptase from human colorectal mucosa in inflammatory bowel disease, Scand. J. Gastroenterol, 36, 174, 10.1080/003655201750065933
Cho, 2011, Nafamostat mesilate attenuates colonic inflammation and mast cell infiltration in the experimental colitis, Int. Immunopharmacol, 11, 412, 10.1016/j.intimp.2010.12.008
Brandt, 2003, Mast cells are required for experimental oral allergen-induced diarrhea, J. Clin. Invest, 112, 1666, 10.1172/JCI19785
Hagel, 2013, Mast cell tryptase levels in gut mucosa in patients with gastrointestinal symptoms caused by food allergy, Int. Arch. Allergy Immunol, 160, 350, 10.1159/000341634
Betts, 1999, Mast cells, eosinophils and antibody-mediated cellular cytotoxicity are not critical in resistance to Trichuris muris, Parasite Immunol, 21, 45, 10.1046/j.1365-3024.1999.00200.x
Lantz, 1998, Role for interleukin-3 in mast-cell and basophil development and in immunity to parasites, Nature, 392, 90, 10.1038/32190
Marone, 2005, Mast cells and basophils: friends as well as foes in bronchial asthma?, Trends Immunol, 26, 25, 10.1016/j.it.2004.10.010
Brightling, 2002, Mast-cell infiltration of airway smooth muscle in asthma, N Engl. J. Med, 346, 1699, 10.1056/NEJMoa012705
Brightling, 2003, Comparison of airway immunopathology of eosinophilic bronchitis and asthma, Thorax, 58, 528, 10.1136/thorax.58.6.528
Yu, 2006, Mast cells can promote the development of multiple features of chronic asthma in mice, J. Clin. Invest, 116, 1633, 10.1172/JCI25702
Yu, 2011, Identification of an IFN-γ/mast cell axis in a mouse model of chronic asthma, J. Clin. Invest, 121, 3133, 10.1172/JCI43598
Kawanami, 1979, Ultrastructure of pulmonary mast cells in patients with fibrotic lung disorders, Lab. Invest, 40, 717
Edwards, 2005, c-Kit immunophenotyping and metalloproteinase expression profiles of mast cells in interstitial lung diseases, J. Pathol, 206, 279, 10.1002/path.1780
Yoshizaki, 2008, CD19 regulates skin and lung fibrosis via Toll-like receptor signaling in a model of bleomycin-induced scleroderma, Am. J. Pathol, 172, 1650, 10.2353/ajpath.2008.071049
Reber, 2014, Mast cells contribute to bleomycin-induced lung inflammation and injury in mice through a chymase/mast cell protease 4-dependent mechanism, J. Immunol, 192, 1847, 10.4049/jimmunol.1300875
Sonoda, 1984, Proliferation of peritoneal mast cells in the skin of W/Wv mice that genetically lack mast cells, J. Exp. Med, 160, 138, 10.1084/jem.160.1.138
Kanakura, 1988, Multiple bidirectional alterations of phenotype and changes in proliferative potential during the in vitroin vivo passage of clonal mast cell populations derived from mouse peritoneal mast cells, Blood, 72, 877, 10.1182/blood.V72.3.877.bloodjournal723877
Tsai, 1991, The rat c-kit ligand, stem cell factor, induces the development of connective tissue-type and mucosal mast cells in vivo. Analysis by anatomical distribution, histochemistry, and protease phenotype, J. Exp. Med, 174, 125, 10.1084/jem.174.1.125
Dvorak, 1976, Morphology of delayed-type hypersensitivity reactions in man. II. Ultrastructural alterations affecting the microvasculature and the tissue mast cells, Lab. Invest, 34, 179
Dahlin, 2014, Mast cell progenitors: origin, development and migration to tissues, Mol. Immunol, 63, 9, 10.1016/j.molimm.2014.01.018
Arinobu, 2005, Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis, Proc. Natl. Acad. Sci. USA, 102, 18105, 10.1073/pnas.0509148102
Jones, 2009, Antigen-induced increases in pulmonary mast cell progenitor numbers depend on IL-9 and CD1d-restricted NKT cells, J. Immunol, 183, 5251, 10.4049/jimmunol.0901471
Abramson, 2007, Regulation of the mast cell response to the type 1 Fcɛ receptor, Immunol. Rev, 217, 231, 10.1111/j.1600-065X.2007.00518.x
Reber, 2014, Targeting mast cells in inflammatory diseases, Pharmacol. Ther, 142, 416, 10.1016/j.pharmthera.2014.01.004
Turner, 1999, Signalling through the high-affinity IgE receptor FcɛRI, Nature, 402, B24, 10.1038/35037021
Rivera, 2008, New insights on mast cell activation via the high affinity receptor for IgE, Adv. Immunol, 98, 85, 10.1016/S0065-2776(08)00403-3
Cheng, 2013, Perivascular mast cells dynamically probe cutaneous blood vessels to capture immunoglobulin E, Immunity, 38, 166, 10.1016/j.immuni.2012.09.022
Suzuki, 2014, Molecular editing of cellular responses by the high-affinity receptor for IgE, Science, 343, 1021, 10.1126/science.1246976
Marichal, 2013, A beneficial role for immunoglobulin E in host defense against honeybee venom, Immunity, 39, 963, 10.1016/j.immuni.2013.10.005
Palm, 2013, Bee venom phospholipase A2 induces a primary type 2 response that is dependent on the receptor ST2 and confers protective immunity, Immunity, 39, 976, 10.1016/j.immuni.2013.10.006
Profet, 1991, The function of allergy: immunological defense against toxins, Q Rev. Biol, 66, 23, 10.1086/417049
Abraham, 2010, Mast cell-orchestrated immunity to pathogens, Nat. Rev. Immunol, 10, 440, 10.1038/nri2782
Supajatura, 2002, Differential responses of mast cell Toll-like receptors 2 and 4 in allergy and innate immunity, J. Clin. Invest, 109, 1351, 10.1172/JCI0214704
Metz, 2006, Mast cells can enhance resistance to snake and honeybee venoms, Science, 313, 526, 10.1126/science.1128877
Akahoshi, 2011, Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice, J. Clin. Invest, 121, 4180, 10.1172/JCI46139
Schneider, 2007, Molecular mechanism of mast cell mediated innate defense against endothelin and snake venom sarafotoxin, J. Exp. Med, 204, 2629, 10.1084/jem.20071262
Ali, 2010, Regulation of human mast cell and basophil function by anaphylatoxins C3a and C5a, Immunol. Lett, 128, 36, 10.1016/j.imlet.2009.10.007
Schafer, 2013, Mast cell anaphylatoxin receptor expression can enhance IgE-dependent skin inflammation in mice, J. Allergy Clin. Immunol, 131, 541, 10.1016/j.jaci.2012.05.009
Kajiwara, 2010, Activation of human mast cells through the platelet-activating factor receptor, J. Allergy Clin. Immunol, 125, 1137, 10.1016/j.jaci.2010.01.056
Metz, 2011, Evidence for non-allergic mast cell activation in pollen-associated inflammation, J. Invest. Dermatol, 131, 987, 10.1038/jid.2010.419
Cirino, 1997, Factor Xa as an interface between coagulation and inflammation. Molecular mimicry of factor Xa association with effector cell protease receptor-1 induces acute inflammation in vivo, J. Clin. Invest, 99, 2446, 10.1172/JCI119428
Cirino, 1996, Thrombin functions as an inflammatory mediator through activation of its receptor, J. Exp. Med, 183, 821, 10.1084/jem.183.3.821
Enoksson, 2011, Mast cells as sensors of cell injury through IL-33 recognition, J. Immunol, 186, 2523, 10.4049/jimmunol.1003383
Lunderius-Andersson, 2012, Mast cells respond to cell injury through the recognition of IL-33, Front. Immunol, 3, 82, 10.3389/fimmu.2012.00082
Kaur, 2011, Mast cell-airway smooth muscle crosstalk: the role of thymic stromal lymphopoietin, Chest, 142, 76, 10.1378/chest.11-1782
Zhou, 2013, Aryl hydrocarbon receptor controls murine mast cell homeostasis, Blood, 121, 3195, 10.1182/blood-2012-08-453597
Sibilano, 2012, The aryl hydrocarbon receptor modulates acute and late mast cell responses, J. Immunol, 189, 120, 10.4049/jimmunol.1200009
Pawankar, 1997, Nasal mast cells in perennial allergic rhinitics exhibit increased expression of the FcɛRI, CD40L, IL-4, and IL-13, and can induce IgE synthesis in B cells, J. Clin. Invest, 99, 1492, 10.1172/JCI119311
Nakae, 2006, Mast cells enhance T cell activation: importance of mast cell costimulatory molecules and secreted TNF, J. Immunol, 176, 2238, 10.4049/jimmunol.176.4.2238
Kashiwakura, 2004, T cell proliferation by direct cross-talk between OX40 ligand on human mast cells and OX40 on human T cells: comparison of gene expression profiles between human tonsillar and lung-cultured mast cells, J. Immunol, 173, 5247, 10.4049/jimmunol.173.8.5247
Sibilano, 2012, Modulation of FcɛRI-dependent mast cell response by OX40L via Fyn, PI3K, and RhoA, J. Allergy Clin. Immunol, 130, 751, 10.1016/j.jaci.2012.03.032
Lee, 2013, Activation of human synovial mast cells from rheumatoid arthritis or osteoarthritis patients in response to aggregated IgG through Fcγ receptor I and Fcγ receptor II, Arthritis Rheum, 65, 109, 10.1002/art.37741
Malbec, 2007, The mast cell IgG receptors and their roles in tissue inflammation, Immunol. Rev, 217, 206, 10.1111/j.1600-065X.2007.00510.x
Fantozzi, 1985, Mast cell and neutrophil interactions: a role for superoxide anion and histamine, Agents Actions, 16, 260, 10.1007/BF01983155
Gri, 2008, CD4+CD25+ regulatory T cells suppress mast cell degranulation and allergic responses through OX40-OX40L interaction, Immunity, 29, 771, 10.1016/j.immuni.2008.08.018
Gaudenzio, 2009, Cell-cell cooperation at the T helper cell/mast cell immunological synapse, Blood, 114, 4979, 10.1182/blood-2009-02-202648
Karra, 2011, Down-regulation of mast cell responses through ITIM containing inhibitory receptors, Adv. Exp. Med. Biol, 716, 143, 10.1007/978-1-4419-9533-9_9
Katz, 2002, Inhibitory receptors and allergy, Curr. Opin. Immunol, 14, 698, 10.1016/S0952-7915(02)00400-4
Ott, 2000, Activating and inhibitory signaling in mast cells: new opportunities for therapeutic intervention?, J. Allergy Clin. Immunol, 106, 429, 10.1067/mai.2000.109428
Hill, 1996, Stem cell factor enhances immunoglobulin E-dependent mediator release from cultured rat bone marrow-derived mast cells: activation of previously unresponsive cells demonstrated by a novel ELISPOT assay, Immunology, 87, 326, 10.1046/j.1365-2567.1996.455545.x
Ito, 2012, Stem cell factor programs the mast cell activation phenotype, J. Immunol, 188, 5428, 10.4049/jimmunol.1103366
Komai-Koma, 2012, Interleukin-33 amplifies IgE synthesis and triggers mast cell degranulation via interleukin-4 in naive mice, Allergy, 67, 1118, 10.1111/j.1398-9995.2012.02859.x
Okayama, 2000, Expression of a functional high-affinity IgG receptor, FcγRI, on human mast cells: up-regulation by IFN-γ, J. Immunol, 164, 4332, 10.4049/jimmunol.164.8.4332
Razin, 1983, IgE-mediated release of leukotriene C4, chondroitin sulfate E proteoglycan, β-hexosaminidase, and histamine from cultured bone marrow-derived mouse mast cells, J. Exp. Med, 157, 189, 10.1084/jem.157.1.189
Windelborg Nielsen, 1990, Histamine release from cord blood basophils, Int. Arch. Allergy Appl. Immunol, 93, 314, 10.1159/000235260
Ghosh, 2002, Defective angiogenesis in the inflammatory granulation tissue in histidine decarboxylase-deficient mice but not in mast cell-deficient mice, J. Exp. Med, 195, 973, 10.1084/jem.20011782
Xu, 2006, Neutrophil histamine contributes to inflammation in mycoplasma pneumonia, J. Exp. Med, 203, 2907, 10.1084/jem.20061232
Caughey, 2011, Mast cell proteases as protective and inflammatory mediators, Adv. Exp. Med. Biol, 716, 212, 10.1007/978-1-4419-9533-9_12
Pejler, 2010, Mast cell proteases: multifaceted regulators of inflammatory disease, Blood, 115, 4981, 10.1182/blood-2010-01-257287
Huang, 1998, Induction of a selective and persistent extravasation of neutrophils into the peritoneal cavity by tryptase mouse mast cell protease 6, J. Immunol, 160, 1910, 10.4049/jimmunol.160.4.1910
Algermissen, 1999, Purification of mast cell proteases from murine skin, Exp. Dermatol, 8, 413, 10.1111/j.1600-0625.1999.tb00391.x
Compton, 2000, Human mast cell tryptase stimulates the release of an IL-8-dependent neutrophil chemotactic activity from human umbilical vein endothelial cells (HUVEC), Clin. Exp. Immunol, 121, 31, 10.1046/j.1365-2249.2000.01271.x
Gallwitz, 2006, Expansion of the mast cell chymase locus over the past 200 million years of mammalian evolution, Immunogenetics, 58, 655, 10.1007/s00251-006-0126-1
Tchougounova, 2003, The chymase, mouse mast cell protease 4, constitutes the major chymotrypsin-like activity in peritoneum and ear tissue. A role for mouse mast cell protease 4 in thrombin regulation and fibronectin turnover, J. Exp. Med, 198, 423, 10.1084/jem.20030671
Andersson, 2008, The extended cleavage specificity of the rodent β-chymases rMCP-1 and mMCP-4 reveal major functional similarities to the human mast cell chymase, Mol. Immunol, 45, 766, 10.1016/j.molimm.2007.06.360
Walsh, 1991, Human dermal mast cells contain and release tumor necrosis factor α, which induces endothelial leukocyte adhesion molecule 1, Proc. Natl. Acad. Sci. USA, 88, 4220, 10.1073/pnas.88.10.4220
Frangogiannis, 1998, Resident cardiac mast cells degranulate and release preformed TNF-α, initiating the cytokine cascade in experimental canine myocardial ischemia/reperfusion, Circulation, 98, 699, 10.1161/01.CIR.98.7.699
Gordon, 1990, Mast cells as a source of both preformed and immunologically inducible TNF-α/cachectin, Nature, 346, 274, 10.1038/346274a0
Kunder, 2009, Mast cell-derived particles deliver peripheral signals to remote lymph nodes, J. Exp. Med, 206, 2455, 10.1084/jem.20090805
Austen, 2005, The mast cell and the cysteinyl leukotrienes, Novartis Found. Symp, 271, 166, 10.1002/9780470033449.ch13
Boyce, 2007, Mast cells and eicosanoid mediators: a system of reciprocal paracrine and autocrine regulation, Immunol. Rev, 217, 168, 10.1111/j.1600-065X.2007.00512.x
Dreskin, 1999, Production of TNF-α by murine bone marrow derived mast cells activated by the bacterial fimbrial protein, FimH, Clin. Immunol, 90, 420, 10.1006/clim.1998.4657
Malaviya, 1996, Mast cell modulation of neutrophil influx and bacterial clearance at sites of infection through TNF-α, Nature, 381, 77, 10.1038/381077a0
Gordon, 1994, Promotion of mouse fibroblast collagen gene expression by mast cells stimulated via the FcɛRI. Role for mast cell-derived transforming growth factor β and tumor necrosis factor α, J. Exp. Med, 180, 2027, 10.1084/jem.180.6.2027
Burd, 1989, Interleukin 3-dependent and -independent mast cells stimulated with IgE and antigen express multiple cytokines, J. Exp. Med, 170, 245, 10.1084/jem.170.1.245
Hagaman, 2001, Secretion of interleukin-1 receptor antagonist from human mast cells after immunoglobulin E-mediated activation and after segmental antigen challenge, Am. J. Respir. Cell Mol. Biol, 25, 685, 10.1165/ajrcmb.25.6.4541
Lin, 2002, Pseudomonas aeruginosa activates human mast cells to induce neutrophil transendothelial migration via mast cell-derived IL-1 α and β, J. Immunol, 169, 4522, 10.4049/jimmunol.169.8.4522
Oldford, 2010, A critical role for mast cells and mast cell-derived IL-6 in TLR2-mediated inhibition of tumor growth, J. Immunol, 185, 7067, 10.4049/jimmunol.1001137
Liu, 2009, Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice, Nat. Med, 15, 940, 10.1038/nm.1994
Ishizuka, 1999, Interleukin-10 is localized to and released by human lung mast cells, Clin. Exp. Allergy, 29, 1424, 10.1046/j.1365-2222.1999.00636.x
Grimbaldeston, 2007, Mast cell-derived interleukin 10 limits skin pathology in contact dermatitis and chronic irradiation with ultraviolet B, Nat. Immunol, 8, 1095, 10.1038/ni1503
Song, 2012, IL-12 and IL-10 production are differentially regulated by phosphatidylinositol 3-kinase in mast cells, Scand. J. Immunol, 75, 266, 10.1111/j.1365-3083.2011.02660.x
Mrabet-Dahbi, 2009, Murine mast cells secrete a unique profile of cytokines and prostaglandins in response to distinct TLR2 ligands, Exp. Dermatol, 18, 437, 10.1111/j.1600-0625.2009.00878.x
Buckland, 2010, New role for mast cells as IL-17-expressing effector cells in established RA, Nat. Rev. Rheumatol, 6, 243, 10.1038/nrrheum.2010.50
Hueber, 2010, Mast cells express IL-17A in rheumatoid arthritis synovium, J. Immunol, 184, 3336, 10.4049/jimmunol.0903566
Boesiger, 1998, Mast cells can secrete vascular permeability factor/vascular endothelial cell growth factor and exhibit enhanced release after immunoglobulin E-dependent upregulation of Fcɛ receptor I expression, J. Exp. Med, 188, 1135, 10.1084/jem.188.6.1135
Grützkau, 1998, Synthesis, storage, and release of vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) by human mast cells: implications for the biological significance of VEGF206, Mol. Biol. Cell, 9, 875, 10.1091/mbc.9.4.875
Detoraki, 2009, Vascular endothelial growth factors synthesized by human lung mast cells exert angiogenic effects, J. Allergy Clin. Immunol, 123, 1142, 10.1016/j.jaci.2009.01.044
Zhang, 1998, Human mast cells express stem cell factor, J. Pathol, 186, 59, 10.1002/(SICI)1096-9896(199809)186:1<59::AID-PATH140>3.0.CO;2-J
de Paulis, 1999, Stem cell factor is localized in, released from, and cleaved by human mast cells, J. Immunol, 163, 2799, 10.4049/jimmunol.163.5.2799
Sibilano, 2014, Mast cell activation: a complex interplay of positive and negative signaling pathways, Eur. J. Immunol, 44, 2558, 10.1002/eji.201444546
Reber, 2012, New models for analyzing mast cell functions in vivo, Trends Immunol, 33, 613, 10.1016/j.it.2012.09.008
Oka, 2012, Evidence questioning cromolyn's effectiveness and selectivity as a ‘mast cell stabilizer’ in mice, Lab. Invest, 92, 1472, 10.1038/labinvest.2012.116
Dawicki, 2007, New and emerging roles for mast cells in host defence, Curr. Opin. Immunol, 19, 31, 10.1016/j.coi.2006.11.006
Grimbaldeston, 2005, Mast cell-deficient W-sash c-kit mutant KitW-sh/W-sh mice as a model for investigating mast cell biology in vivo, Am. J. Pathol, 167, 835, 10.1016/S0002-9440(10)62055-X
Grimbaldeston, 2006, Effector and potential immunoregulatory roles of mast cells in IgE-associated acquired immune responses, Curr. Opin. Immunol, 18, 751, 10.1016/j.coi.2006.09.011
Zhou, 2007, Mast cell deficiency in Kit(W-sh mice does not impair antibody-mediated arthritis, J. Exp. Med, 204, 2797, 10.1084/jem.20071391
Piliponsky, 2010, Mast cell-derived TNF can exacerbate mortality during severe bacterial infections in C57BL/6-KitW-sh/W-sh mice, Am. J. Pathol, 176, 926, 10.2353/ajpath.2010.090342
Nigrovic, 2008, Genetic inversion in mast cell-deficient Wsh mice interrupts corin and manifests as hematopoietic and cardiac aberrancy, Am. J. Pathol, 173, 1693, 10.2353/ajpath.2008.080407
Chervenick, 1969, Decreased neutrophils and megakaryocytes in anemic mice of genotype W/Wv, J. Cell. Physiol, 73, 25, 10.1002/jcp.1040730104
Nagle, 1995, Physical mapping of the TecGabrb1 loci reveals that the Wsh mutation on mouse chromosome 5 is associated with an inversion, Hum. Mol. Genet, 4, 2073, 10.1093/hmg/4.11.2073
Lyon, 1982, A new allele sash (Wsh) at the W-locus and a spontaneous recessive lethal in mice, Genet. Res, 39, 315, 10.1017/S001667230002098X
Wolters, 2005, Tissue-selective mast cell reconstitution and differential lung gene expression in mast cell-deficient KitW-sh/KitW-sh sash mice, Clin. Exp. Allergy, 35, 82, 10.1111/j.1365-2222.2005.02136.x
Huizinga, 1995, W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity, Nature, 373, 347, 10.1038/373347a0
Galli, 1987, Genetically mast-cell-deficient W/Wvand Sl/Sldmice. Their value for the analysis of the roles of mast cells in biologic responses in vivo, Am. J. Pathol, 127, 191
Lilla, 2011, Reduced mast cell and basophil numbers and function in Cpa3-Cre; Mcl-1fl/fl mice, Blood, 118, 6930, 10.1182/blood-2011-03-343962
Dudeck, 2011, Mast cells are key promoters of contact allergy that mediate the adjuvant effects of haptens, Immunity, 34, 973, 10.1016/j.immuni.2011.03.028
Scholten, 2008, Mast cell-specific Cre/loxP-mediated recombination in vivo, Transgenic Res, 17, 307, 10.1007/s11248-007-9153-4
Musch, 2008, Generation and characterization of alpha-chymase-Cre transgenic mice, Genesis, 46, 163, 10.1002/dvg.20378
Otsuka, 2011, Requirement of interaction between mast cells and skin dendritic cells to establish contact hypersensitivity, PLoS One, 6, e25538, 10.1371/journal.pone.0025538
Feyerabend, 2011, Cre-mediated cell ablation contests mast cell contribution in models of antibody- and T cell-mediated autoimmunity, Immunity, 35, 832, 10.1016/j.immuni.2011.09.015
Furumoto, 2011, PTEN deficiency in mast cells causes a mastocytosis-like proliferative disease that heightens allergic responses and vascular permeability, Blood, 118, 5466, 10.1182/blood-2010-09-309955
Rodewald, 2012, Widespread immunological functions of mast cells: fact or fiction?, Immunity, 37, 13, 10.1016/j.immuni.2012.07.007
Galli, S.J., Tsai, M., Marichal, T., Chugunova, E., Reber, L.L. & Pejler, G. Approaches for analyzing the roles of mast cells and their proteases in vivo. Adv. Immunol. (in press).
Wernersson, 2014, Mast cell secretory granules: armed for battle, Nat. Rev. Immunol, 14, 478, 10.1038/nri3690
Groschwitz, 2009, Mast cells regulate homeostatic intestinal epithelial migration and barrier function by a chymase/Mcpt4-dependent mechanism, Proc. Natl. Acad. Sci. USA, 106, 22381, 10.1073/pnas.0906372106
Berkes, 2003, Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation, Gut, 52, 439, 10.1136/gut.52.3.439
Perdue, 1991, Role of mast cells in ion transport abnormalities associated with intestinal anaphylaxis. Correction of the diminished secretory response in genetically mast cell-deficient W/Wv mice by bone marrow transplantation, J. Clin. Invest, 87, 687, 10.1172/JCI115047
Groschwitz, 2009, Intestinal barrier function: molecular regulation and disease pathogenesis, J. Allergy Clin. Immunol, 124, 3, 10.1016/j.jaci.2009.05.038
McDermott, 2003, Mast cells disrupt epithelial barrier function during enteric nematode infection, Proc. Natl. Acad. Sci. USA, 100, 7761, 10.1073/pnas.1231488100
Chabot, 1988, The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus, Nature, 335, 88, 10.1038/335088a0
Kapur, 1999, The presence of novel amino acids in the cytoplasmic domain of stem cell factor results in hematopoietic defects in Steel17H mice, Blood, 94, 1915, 10.1182/blood.V94.6.1915
Wang, 1995, Substance P induces ion secretion in mouse small intestine through effects on enteric nerves and mast cells, Am. J. Physiol, 269, G85
Bousquet, 2000, Asthma. From bronchoconstriction to airways inflammation and remodeling, Am. J. Respir. Crit. Care Med, 161, 1720, 10.1164/ajrccm.161.5.9903102
Fish, 1999, Airway remodeling and persistent airway obstruction in asthma, J. Allergy Clin. Immunol, 104, 509, 10.1016/S0091-6749(99)70315-5
Wills-Karp, 1999, Immunologic basis of antigen-induced airway hyperresponsiveness, Annu. Rev. Immunol, 17, 255, 10.1146/annurev.immunol.17.1.255
Holt, 2012, Viral infections and atopy in asthma pathogenesis: new rationales for asthma prevention and treatment, Nat. Med, 18, 726, 10.1038/nm.2768
Wenzel, 2012, Asthma phenotypes: the evolution from clinical to molecular approaches, Nat. Med, 18, 716, 10.1038/nm.2678
Slager, 2012, Genetics of asthma susceptibility and severity, Clin. Chest Med, 33, 431, 10.1016/j.ccm.2012.05.005
Meyers, 2014, Asthma genetics and personalised medicine, Lancet Respir. Med, 2, 405, 10.1016/S2213-2600(14)70012-8
Dougherty, 2010, Accumulation of intraepithelial mast cells with a unique protease phenotype in TH2-high asthma, J. Allergy Clin. Immunol, 125, 1046, 10.1016/j.jaci.2010.03.003
Balzar, 2011, Mast cell phenotype, location, and activation in severe asthma. Data from the Severe Asthma Research Program, Am. J. Respir. Crit. Care Med, 183, 299, 10.1164/rccm.201002-0295OC
Carroll, 2002, Distribution and degranulation of airway mast cells in normal and asthmatic subjects, Eur. Respir. J, 19, 879, 10.1183/09031936.02.00275802
Liesker, 2007, Mast cell numbers in airway smooth muscle and PC20AMP in asthma and COPD, Respir. Med, 101, 882, 10.1016/j.rmed.2006.10.001
Lamb, 1982, Intra-epithelial mast cells in human airway epithelium: evidence for smoking-induced changes in their frequency, Thorax, 37, 334, 10.1136/thx.37.5.334
Holgate, 1999, The bronchial epithelium as a key regulator of airway inflammation and remodelling in asthma, Clin. Exp. Allergy, 29 (Suppl 2), 90, 10.1046/j.1365-2222.1999.00016.x
Wilson, 2001, Assessing the evidence for remodelling of the airway in asthma, Pulm. Pharmacol. Ther, 14, 229, 10.1006/pupt.2001.0294
Altin, 2010, Understanding the genetic regulation of IgE production, Blood Rev, 24, 163, 10.1016/j.blre.2010.06.002
Takhar, 2007, Class switch recombination to IgE in the bronchial mucosa of atopic and nonatopic patients with asthma, J. Allergy Clin. Immunol, 119, 213, 10.1016/j.jaci.2006.09.045
Williams, 2000, Mast cells can amplify airway reactivity and features of chronic inflammation in an asthma model in mice, J. Exp. Med, 192, 455, 10.1084/jem.192.3.455
Taube, 2004, Mast cells, FcɛRI, and IL-13 are required for development of airway hyperresponsiveness after aerosolized allergen exposure in the absence of adjuvant, J. Immunol, 172, 6398, 10.4049/jimmunol.172.10.6398
Nakae, 2007, Mast cell-derived TNF contributes to airway hyperreactivity, inflammation, and TH2 cytokine production in an asthma model in mice, J. Allergy Clin. Immunol, 120, 48, 10.1016/j.jaci.2007.02.046
Reuter, 2008, Mast cell-derived tumour necrosis factor is essential for allergic airway disease, Eur. Respir. J, 31, 773, 10.1183/09031936.00058907
Kung, 1995, Mast cells modulate allergic pulmonary eosinophilia in mice, Am. J. Respir. Cell Mol. Biol, 12, 404, 10.1165/ajrcmb.12.4.7695919
Kobayashi, 2000, An essential role of mast cells in the development of airway hyperresponsiveness in a murine asthma model, J. Immunol, 164, 3855, 10.4049/jimmunol.164.7.3855
Nogami, 1990, Experimental pulmonary eosinophilia in mice by Ascaris suum extract, Am. Rev. Respir. Dis, 141, 1289, 10.1164/ajrccm/141.5_Pt_1.1289
Okudaira, 1991, T-cell-dependent accumulation of eosinophils in the lung and its inhibition by monoclonal anti-interleukin-5, Int. Arch. Allergy Appl. Immunol, 94, 171, 10.1159/000235354
Brusselle, 1994, Attenuation of allergic airway inflammation in IL-4 deficient mice, Clin. Exp. Allergy, 24, 73, 10.1111/j.1365-2222.1994.tb00920.x
Takeda, 1997, Development of eosinophilic airway inflammation and airway hyperresponsiveness in mast cell-deficient mice, J. Exp. Med, 186, 449, 10.1084/jem.186.3.449
Becker, 2011, Genetic variation determines mast cell functions in experimental asthma, J. Immunol, 186, 7225, 10.4049/jimmunol.1100676
Yang, 2009, Pathogenesis of steroid-resistant airway hyperresponsiveness: interaction between IFN-γ and TLR4/MyD88 pathways, J. Immunol, 182, 5107, 10.4049/jimmunol.0803468
Li, 2010, IL-27/IFN-γ induce MyD88-dependent steroid-resistant airway hyperresponsiveness by inhibiting glucocorticoid signaling in macrophages, J. Immunol, 185, 4401, 10.4049/jimmunol.1001039
Hunter, 2005, New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions, Nat. Rev. Immunol, 5, 521, 10.1038/nri1648
Bullens, 2006, IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx?, Respir. Res, 7, 135, 10.1186/1465-9921-7-135
Iwakura, 2011, Functional specialization of interleukin-17 family members, Immunity, 34, 149, 10.1016/j.immuni.2011.02.012
Tan, 1996, Double-blind controlled trial of effect of housedust-mite allergen avoidance on atopic dermatitis, Lancet, 347, 15, 10.1016/S0140-6736(96)91556-1
He, 2007, Epicutaneous antigen exposure induces a Th17 response that drives airway inflammation after inhalation challenge, Proc. Natl. Acad. Sci. USA, 104, 15817, 10.1073/pnas.0706942104
Hellings, 2003, Interleukin-17 orchestrates the granulocyte influx into airways after allergen inhalation in a mouse model of allergic asthma, Am. J. Respir. Cell Mol. Biol, 28, 42, 10.1165/rcmb.4832
Lin, 2011, Mast cells and neutrophils release IL-17 through extracellular trap formation in psoriasis, J. Immunol, 187, 490, 10.4049/jimmunol.1100123
Suurmond, 2011, Mast cells are the main interleukin 17-positive cells in anticitrullinated protein antibody-positive and -negative rheumatoid arthritis and osteoarthritis synovium, Arthritis Res. Ther, 13, R150, 10.1186/ar3466
Préfontaine, 2010, Increased IL-33 expression by epithelial cells in bronchial asthma, J. Allergy Clin. Immunol, 125, 752, 10.1016/j.jaci.2009.12.935
Préfontaine, 2009, Increased expression of IL-33 in severe asthma: evidence of expression by airway smooth muscle cells, J. Immunol, 183, 5094, 10.4049/jimmunol.0802387
Gudbjartsson, 2009, Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction, Nat. Genet, 41, 342, 10.1038/ng.323
Moffatt, 2010, A large-scale, consortium-based genomewide association study of asthma, N Engl. J. Med, 363, 1211, 10.1056/NEJMoa0906312
Torgerson, 2011, Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations, Nat. Genet, 43, 887, 10.1038/ng.888
Pecaric-Petkovic, 2009, Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33, Blood, 113, 1526, 10.1182/blood-2008-05-157818
Yagami, 2010, IL-33 mediates inflammatory responses in human lung tissue cells, J. Immunol, 185, 5743, 10.4049/jimmunol.0903818
Junttila, 2013, Efficient cytokine-induced IL-13 production by mast cells requires both IL-33 and IL-3, J. Allergy Clin. Immunol, 132, 704, 10.1016/j.jaci.2013.03.033
Liew, 2010, Disease-associated functions of IL-33: the new kid in the IL-1 family, Nat. Rev. Immunol, 10, 103, 10.1038/nri2692
Jung, 2013, IL-33 induces a hyporesponsive phenotype in human and mouse mast cells, J. Immunol, 190, 531, 10.4049/jimmunol.1201576
Waern, 2009, Mouse mast cell protease 4 is the major chymase in murine airways and has a protective role in allergic airway inflammation, J. Immunol, 183, 6369, 10.4049/jimmunol.0900180
Waern, 2013, Mast cell chymase modulates IL-33 levels and controls allergic sensitization in dust-mite induced airway inflammation, Mucosal Immunol, 6, 911, 10.1038/mi.2012.129
Sicherer, 2009, Food allergy: recent advances in pathophysiology and treatment, Annu. Rev. Med, 60, 261, 10.1146/annurev.med.60.042407.205711
Bock, 2001, Fatalities due to anaphylactic reactions to foods, J. Allergy Clin. Immunol, 107, 191, 10.1067/mai.2001.112031
Bock, 2007, Further fatalities caused by anaphylactic reactions to food, 2001-2006, J. Allergy Clin. Immunol, 119, 1016, 10.1016/j.jaci.2006.12.622
Finkelman, 2007, Anaphylaxis: lessons from mouse models, J. Allergy Clin. Immunol, 120, 506, 10.1016/j.jaci.2007.07.033
Tsujimura, 2008, Basophils play a pivotal role in immunoglobulin-G-mediated but not immunoglobulin-E-mediated systemic anaphylaxis, Immunity, 28, 581, 10.1016/j.immuni.2008.02.008
Jonsson, 2011, Mouse and human neutrophils induce anaphylaxis, J. Clin. Invest, 121, 1484, 10.1172/JCI45232
Sun, 2007, Impact of CD40 ligand, B cells, and mast cells in peanut-induced anaphylactic responses, J. Immunol, 179, 6696, 10.4049/jimmunol.179.10.6696
Reber, 2013, Selective ablation of mast cells or basophils reduces peanut-induced anaphylaxis in mice, J. Allergy Clin. Immunol, 132, 881, 10.1016/j.jaci.2013.06.008
Arias, 2011, Distinct immune effector pathways contribute to the full expression of peanut-induced anaphylactic reactions in mice, J. Allergy Clin. Immunol, 127, 1552, 10.1016/j.jaci.2011.03.044
Smit, 2011, Contribution of classic and alternative effector pathways in peanut-induced anaphylactic responses, PLoS One, 6, e28917, 10.1371/journal.pone.0028917
Khodoun, 2009, Peanuts can contribute to anaphylactic shock by activating complement, J. Allergy Clin. Immunol, 123, 342, 10.1016/j.jaci.2008.11.004
Ghosh, 2012, μ-Chain-deficient mice possess B-1 cells and produce IgG and IgE, but not IgA, following systemic sensitization and inhalational challenge in a fungal asthma model, J. Immunol, 189, 1322, 10.4049/jimmunol.1200138
Orinska, 2002, Novel B cell population producing functional IgG in the absence of membrane IgM expression, Eur. J. Immunol, 32, 3472, 10.1002/1521-4141(200212)32:12<3472::AID-IMMU3472>3.0.CO;2-F
Perona-Wright, 2008, Cutting edge: Helminth infection induces IgE in the absence of mu- or delta-chain expression, J. Immunol, 181, 6697, 10.4049/jimmunol.181.10.6697
Simons, 2009, Anaphylaxis: recent advances in assessment and treatment, J. Allergy Clin. Immunol, 124, 625, 10.1016/j.jaci.2009.08.025
Vadas, 2008, Platelet-activating factor, PAF acetylhydrolase, and severe anaphylaxis, N Engl. J. Med, 358, 28, 10.1056/NEJMoa070030
Vadas, 2013, Platelet-activating factor, histamine, and tryptase levels in human anaphylaxis, J. Allergy Clin. Immunol, 131, 144, 10.1016/j.jaci.2012.08.016
Cheifetz, 2003, The incidence and management of infusion reactions to infliximab: a large center experience, Am. J. Gastroenterol, 98, 1315, 10.1111/j.1572-0241.2003.07457.x
Sampson, 2006, Second symposium on the definition and management of anaphylaxis: summary report—Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium, J. Allergy Clin. Immunol, 117, 391, 10.1016/j.jaci.2005.12.1303
Bischoff, 2005, Gastrointestinal food allergy: new insights into pathophysiology and clinical perspectives, Gastroenterology, 128, 1089, 10.1053/j.gastro.2004.08.015
Hogan, 2012, Food-induced anaphylaxis: mast cells as modulators of anaphylactic severity, Semin. Immunopathol, 34, 643, 10.1007/s00281-012-0320-1
Caffarelli, 1998, Clinical food hypersensitivity: the relevance of duodenal immunoglobulin E-positive cells, Pediatr. Res, 44, 485, 10.1203/00006450-199810000-00004
Nolte, 1989, Comparison of intestinal mast cell and basophil histamine release in children with food allergic reactions, Allergy, 44, 554, 10.1111/j.1398-9995.1989.tb04200.x
Wang, 2010, Peanut-induced intestinal allergy is mediated through a mast cell-IgE-FcɛRI-IL-13 pathway, J. Allergy Clin. Immunol, 126, 306, 10.1016/j.jaci.2010.05.017
Forbes, 2008, IL-9- and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity, J. Exp. Med, 205, 897, 10.1084/jem.20071046
Boyce, 2011, Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-sponsored expert panel report, Nutr. Res, 31, 61, 10.1016/j.nutres.2011.01.001
Rance, 2008, Food allergy in children suffering from atopic eczema, Pediatr. Allergy Immunol, 19, 279, 10.1111/j.1399-3038.2008.00719.x
Noti, 2014, Exposure to food allergens through inflamed skin promotes intestinal food allergy through the thymic stromal lymphopoietin-basophil axis, J. Allergy Clin. Immunol, 133, 1390, 10.1016/j.jaci.2014.01.021
Burton, 2014, Immunoglobulin E signal inhibition during allergen ingestion leads to reversal of established food allergy and induction of regulatory T cells, Immunity, 41, 141, 10.1016/j.immuni.2014.05.017
Choi, 2015, Mast cell mediator responses and their suppression by pathogenic and commensal microorganisms, Mol. Immunol, 63, 74, 10.1016/j.molimm.2014.02.006
Chan, 2012, Plasticity in mast cell responses during bacterial infections, Curr. Opin. Microbiol, 15, 78, 10.1016/j.mib.2011.10.007
Kumar, 2010, Mast cells: emerging sentinel innate immune cells with diverse role in immunity, Mol. Immunol, 48, 14, 10.1016/j.molimm.2010.07.009
Galli, 2010, Mast cells in allergy and infection: versatile effector and regulatory cells in innate and adaptive immunity, Eur. J. Immunol, 40, 1843, 10.1002/eji.201040559
Woodbury, 1984, Mucosal mast cells are functionally active during spontaneous expulsion of intestinal nematode infections in rat, Nature, 312, 450, 10.1038/312450a0
Askenase, 1977, Immune inflammatory responses to parasites: the role of basophils, mast cells and vasoactive amines, Am. J. Trop. Med. Hyg, 26, 96, 10.4269/ajtmh.1977.26.96
Knight, 2000, Delayed expulsion of the nematode Trichinella spiralis in mice lacking the mucosal mast cell-specific granule chymase, mouse mast cell protease-1, J. Exp. Med, 192, 1849, 10.1084/jem.192.12.1849
Barrett, 1988, The immune response to nematode parasites: modulation of mast cell numbers and function during Strongyloides stercoralis infections in nonhuman primates, Am. J. Trop. Med. Hyg, 38, 574, 10.4269/ajtmh.1988.38.574
Gustowska, 1983, Increase of mucosal mast cells in the jejunum of patients infected with Trichinella spiralis, Int. Arch. Allergy Appl. Immunol, 71, 304, 10.1159/000233412
Allen, 2011, Diversity and dialogue in immunity to helminths, Nat. Rev. Immunol, 11, 375, 10.1038/nri2992
Grencis, 2014, Immunity to gastrointestinal nematodes: mechanisms and myths, Immunol. Rev, 260, 183, 10.1111/imr.12188
Maizels, 2009, Regulation of pathogenesis and immunity in helminth infections, J. Exp. Med, 206, 2059, 10.1084/jem.20091903
Taylor, 2012, T cells in helminth infection: the regulators and the regulated, Trends Immunol, 33, 181, 10.1016/j.it.2012.01.001
Ohnmacht, 2010, Basophils protect against reinfection with hookworms independently of mast cells and memory Th2 cells, J. Immunol, 184, 344, 10.4049/jimmunol.0901841
Crowle, 1983, Mucosal mast cell reconstitution and Nippostrongylus brasiliensis rejection by W/Wv mice, J. Parasitol, 69, 66, 10.2307/3281276
Abe, 1987, Reconstitution of mucosal mast cells in W/WV mice by adoptive transfer of bone marrow-derived cultured mast cells and its effects on the protective capacity to Strongyloides ratti-infection, Parasite Immunol, 9, 31, 10.1111/j.1365-3024.1987.tb00486.x
Sasaki, 2005, IL-18 with IL-2 protects against Strongyloides venezuelensis infection by activating mucosal mast cell-dependent type 2 innate immunity, J. Exp. Med, 202, 607, 10.1084/jem.20042202
Khan, 1993, Defective mucosal immunity and normal systemic immunity of Mongolian gerbils, Meriones unguiculatus, to reinfection with Strongyloides venezuelensis, Parasite Immunol, 15, 565, 10.1111/pim.1993.15.10.565
Ha, 1983, Delayed expulsion of adult Trichinella spiralis by mast cell-deficient W/Wv mice, Infect. Immun, 41, 445, 10.1128/iai.41.1.445-447.1983
Oku, 1984, Expulsion of Trichinella spiralis from the intestine of W/Wv mice reconstituted with haematopoietic and lymphopoietic cells and origin of mucosal mast cells, Immunology, 53, 337
Koyama, 2000, Mucosal mast cell responses are not required for protection against infection with the murine nematode parasite Trichuris muris, Parasite Immunol, 22, 13, 10.1046/j.1365-3024.2000.00270.x
Hepworth, 2012, Mast cells orchestrate type 2 immunity to helminths through regulation of tissue-derived cytokines, Proc. Natl. Acad. Sci. USA, 109, 6644, 10.1073/pnas.1112268109
Abe, 1987, Localization of mucosal mast cells in W/Wv mice after reconstitution with bone marrow cells or cultured mast cells, and its relation to the protective capacity to Strongyloides ratti infection, Parasite Immunol, 9, 477, 10.1111/j.1365-3024.1987.tb00524.x
Wedemeyer, 2005, Decreased susceptibility of mast cell-deficient KitW/KitW-v mice to the development of 1, 2-dimethylhydrazine-induced intestinal tumors, Lab. Invest, 85, 388, 10.1038/labinvest.3700232
Shin, 2008, Mouse mast cell tryptase mMCP-6 is a critical link between adaptive and innate immunity in the chronic phase of Trichinella spiralis infection, J. Immunol, 180, 4885, 10.4049/jimmunol.180.7.4885
Blankenhaus, 2014, Foxp3+ regulatory T cells delay expulsion of intestinal nematodes by suppression of IL-9-driven mast cell activation in BALB/c but not in C57BL/6 mice, PLoS Pathog, 10, e1003913, 10.1371/journal.ppat.1003913
Newlands, 1995, Stem cell factor contributes to intestinal mucosal mast cell hyperplasia in rats infected with Nippostrongylus brasiliensis or Trichinella spiralis, but anti-stem cell factor treatment decreases parasite egg production during N brasiliensis infection, Blood, 86, 1968, 10.1182/blood.V86.5.1968.bloodjournal8651968
Arizono, 1993, Infection of Nippostrongylus brasiliensis induces development of mucosal-type but not connective tissue-type mast cells in genetically mast cell-deficient Ws/Ws rats, Blood, 81, 2572, 10.1182/blood.V81.10.2572.2572
Townsend, 2000, IL-9-deficient mice establish fundamental roles for IL-9 in pulmonary mastocytosis and goblet cell hyperplasia but not T cell development, Immunity, 13, 573, 10.1016/S1074-7613(00)00056-X
Harris, 2011, To B or not to B: B cells and the Th2-type immune response to helminths, Trends Immunol, 32, 80, 10.1016/j.it.2010.11.005
Pritchard, 1993, Immunity to helminths: is too much IgE parasite—rather than host-protective?, Parasite Immunol, 15, 5, 10.1111/j.1365-3024.1993.tb00566.x
Zhu, 2002, A novel human immunoglobulin FcγFcε bifunctional fusion protein inhibits FcεRI-mediated degranulation, Nat. Med, 8, 518, 10.1038/nm0502-518
Zhu, 2005, A chimeric human-cat fusion protein blocks cat-induced allergy, Nat. Med, 11, 446, 10.1038/nm1219
Echtenacher, 1996, Critical protective role of mast cells in a model of acute septic peritonitis, Nature, 381, 75, 10.1038/381075a0
Maurer, 1998, The c-kit ligand, stem cell factor, can enhance innate immunity through effects on mast cells, J. Exp. Med, 188, 2343, 10.1084/jem.188.12.2343
Maurer, 2004, Mast cells promote homeostasis by limiting endothelin-1-induced toxicity, Nature, 432, 512, 10.1038/nature03085
Mallen-St Clair, 2004, Mast cell dipeptidyl peptidase I mediates survival from sepsis, J. Clin. Invest, 113, 628, 10.1172/JCI200419062
Piliponsky, 2008, Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis, Nat. Med, 14, 392, 10.1038/nm1738
Sutherland, 2008, Mast cell IL-6 improves survival from Klebsiella pneumonia and sepsis by enhancing neutrophil killing, J. Immunol, 181, 5598, 10.4049/jimmunol.181.8.5598
Piliponsky, 2012, The chymase mouse mast cell protease 4 degrades TNF, limits inflammation, and promotes survival in a model of sepsis, Am. J. Pathol, 181, 875, 10.1016/j.ajpath.2012.05.013
Nakano, 2007, Involvement of mast cells in IL-12/23 p40 production is essential for survival from polymicrobial infections, Blood, 109, 4846, 10.1182/blood-2006-09-045641
Kanamaru, 2005, Smad3 deficiency in mast cells provides efficient host protection against acute septic peritonitis, J. Immunol, 174, 4193, 10.4049/jimmunol.174.7.4193
Orinska, 2007, IL-15 constrains mast cell-dependent antibacterial defenses by suppressing chymase activities, Nat. Med, 13, 927, 10.1038/nm1615
Huang, 2001, Evaluation of the substrate specificity of human mast cell tryptase βI and demonstration of its importance in bacterial infections of the lung, J. Biol. Chem, 276, 26276, 10.1074/jbc.M102356200
Thakurdas, 2007, The mast cell-restricted tryptase mMCP-6 has a critical immunoprotective role in bacterial infections, J. Biol. Chem, 282, 20809, 10.1074/jbc.M611842200
Xu, 2006, Mast cells protect mice from Mycoplasma pneumonia, Am. J. Respir. Crit. Care Med, 173, 219, 10.1164/rccm.200507-1034OC
Wershil, 1998, Direct evidence of mast cell involvement in Clostridium difficile toxin A-induced enteritis in mice, Gastroenterology, 114, 956, 10.1016/S0016-5085(98)70315-4
Malaviya, 2001, Role of Janus kinase 3 in mast cell-mediated innate immunity against gram-negative bacteria, Immunity, 15, 313, 10.1016/S1074-7613(01)00184-4
Anderson, 2004, Intracellular bacterial communities of uropathogenic Escherichia coli in urinary tract pathogenesis, Trends Microbiol, 12, 424, 10.1016/j.tim.2004.07.005
Shelburne, 2009, Mast cells augment adaptive immunity by orchestrating dendritic cell trafficking through infected tissues, Cell Host Microbe, 6, 331, 10.1016/j.chom.2009.09.004
Malaviya, 2004, Contribution of mast cells to bacterial clearance and their proliferation during experimental cystitis induced by type 1 fimbriated E. coli, Immunol. Lett, 91, 103, 10.1016/j.imlet.2003.10.005
Chan, 2013, Mast cell interleukin-10 drives localized tolerance in chronic bladder infection, Immunity, 38, 349, 10.1016/j.immuni.2012.10.019
Leveson-Gower, 2013, Mast cells suppress murine GVHD in a mechanism independent of CD4+CD25+ regulatory T cells, Blood, 122, 3659, 10.1182/blood-2013-08-519157
Ronnberg, 2014, Mast cells are activated by Staphylococcus aureus in vitro but do not influence the outcome of intraperitoneal S. aureus infection in vivo, Immunology, 143, 155, 10.1111/imm.12297
Sugiyama, 1977, Histamine release from rat mast cells induced by Sendai virus, Nature, 270, 614, 10.1038/270614a0
Castleman, 1990, Viral bronchiolitis during early life induces increased numbers of bronchiolar mast cells and airway hyperresponsiveness, Am. J. Pathol, 137, 821
Sorden, 1995, Virus-induced increases in bronchiolar mast cells in Brown Norway rats are associated with both local mast cell proliferation and increases in blood mast cell precursors, Lab. Invest, 73, 197
Kulka, 2004, Activation of mast cells by double-stranded RNA: evidence for activation through Toll-like receptor 3, J. Allergy Clin. Immunol, 114, 174, 10.1016/j.jaci.2004.03.049
Orinska, 2005, TLR3-induced activation of mast cells modulates CD8+ T-cell recruitment, Blood, 106, 978, 10.1182/blood-2004-07-2656
Higuchi, 2008, Mast cells play a critical role in the pathogenesis of viral myocarditis, Circulation, 118, 363, 10.1161/CIRCULATIONAHA.107.741595
Zsebo, 1990, Stem cell factor is encoded at the Sl locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor, Cell, 63, 213, 10.1016/0092-8674(90)90302-U
Wang, 2012, Skin mast cells protect mice against vaccinia virus by triggering mast cell receptor S1PR2 and releasing antimicrobial peptides, J. Immunol, 188, 345, 10.4049/jimmunol.1101703
Wang, 2012, Commensal bacteria lipoteichoic acid increases skin mast cell antimicrobial activity against vaccinia viruses, J. Immunol, 189, 1551, 10.4049/jimmunol.1200471
St John, 2013, Contributions of mast cells and vasoactive products, leukotrienes and chymase, to dengue virus-induced vascular leakage, Elife, 2, e00481, 10.7554/eLife.00481
St John, 2013, Influence of mast cells on dengue protective immunity and immune pathology, PLoS Pathog, 9, e1003783, 10.1371/journal.ppat.1003783
St John, 2011, Immune surveillance by mast cells during dengue infection promotes natural killer (NK) and NKT-cell recruitment and viral clearance, Proc. Natl. Acad. Sci. USA, 108, 9190, 10.1073/pnas.1105079108
Ebert, 2014, Mast cells expedite control of pulmonary murine cytomegalovirus infection by enhancing the recruitment of protective CD8 T cells to the lungs, PLoS Pathog, 10, e1004100, 10.1371/journal.ppat.1004100
Sundstrom, 2007, Human tissue mast cells are an inducible reservoir of persistent HIV infection, Blood, 109, 5293, 10.1182/blood-2006-11-058438
Bannert, 2001, Human mast cell progenitors can be infected by macrophagetropic human immunodeficiency virus type 1 and retain virus with maturation in vitro, J. Virol, 75, 10808, 10.1128/JVI.75.22.10808-10814.2001
Sundstrom, 2004, Signaling through Toll-like receptors triggers HIV-1 replication in latently infected mast cells, J. Immunol, 172, 4391, 10.4049/jimmunol.172.7.4391
Li, 2001, Mast cells/basophils in the peripheral blood of allergic individuals who are HIV-1 susceptible due to their surface expression of CD4 and the chemokine receptors CCR3, CCR5, and CXCR4, Blood, 97, 3484, 10.1182/blood.V97.11.3484
McLachlan, 2008, Mast cell activators: a new class of highly effective vaccine adjuvants, Nat. Med, 14, 536, 10.1038/nm1757
Ferry, 2002, G protein-dependent activation of mast cell by peptides and basic secretagogues, Peptides, 23, 1507, 10.1016/S0196-9781(02)00090-6
Aridor, 1993, Activation of exocytosis by the heterotrimeric G protein Gi3, Science, 262, 1569, 10.1126/science.7504324
Paton, 1951, Compound 48/80: a potent histamine liberator, Br. J. Pharmacol. Chemother, 6, 499, 10.1111/j.1476-5381.1951.tb00661.x
Fawcett, 1954, Cytological and pharmacological observations on the release of histamine by mast cells, J. Exp. Med, 100, 217, 10.1084/jem.100.2.217
Rothschild, 1970, Mechanisms of histamine release by compound 48-80, Br. J. Pharmacol, 38, 253, 10.1111/j.1476-5381.1970.tb10354.x
Gushchin, 1981, Histamine releasing and anti-inflammatory activities of MCD-peptide and its modified forms, Agents Actions, 11, 69, 10.1007/BF01991459
Galli, 1987, Ethanol-induced acute gastric injury in mast cell-deficient and congenic normal mice. Evidence that mast cells can augment the area of damage, Am. J. Pathol, 128, 131
Pae, 2010, Chronic allergen challenge induces bronchial mast cell accumulation in BALB/c but not C57BL/6 mice and is independent of IL-9, Immunogenetics, 62, 499, 10.1007/s00251-010-0452-1
Xing, 2011, Protease phenotype of constitutive connective tissue and of induced mucosal mast cells in mice is regulated by the tissue, Proc. Natl. Acad. Sci. USA, 108, 14210, 10.1073/pnas.1111048108
Forsberg, 1999, Abnormal mast cells in mice deficient in a heparin-synthesizing enzyme, Nature, 400, 773, 10.1038/23488
Humphries, 1999, Heparin is essential for the storage of specific granule proteases in mast cells, Nature, 400, 769, 10.1038/23481
Schwartz, 1994, Mast cells: function and contents, Curr. Opin. Immunol, 6, 91, 10.1016/0952-7915(94)90039-6
Craig, 1993, Ultrastructural localization of heparin to human mast cells of the MCTC and MCT types by labeling with antithrombin III-gold, Lab. Invest, 69, 552
Wernersson, 2014, Mast cell secretory granules: armed for battle, Nat. Rev. Immunol, 14, 478, 10.1038/nri3690
Wong, 1999, Identification of a new member of the tryptase family of mouse and human mast cell proteases which possesses a novel COOH-terminal hydrophobic extension, J. Biol. Chem, 274, 30784, 10.1074/jbc.274.43.30784
Xia, 1995, Quantitation of tryptase, chymase, FcɛRIα, and FcɛRIγ mRNAs in human mast cells and basophils by competitive reverse transcription-polymerase chain reaction, J. Immunol, 154, 5472, 10.4049/jimmunol.154.10.5472
Caughey, 2000, Characterization of human γ-tryptases, novel members of the chromosome 16p mast cell tryptase and prostasin gene families, J. Immunol, 164, 6566, 10.4049/jimmunol.164.12.6566
Schechter, 1990, Identification of a cathepsin G-like proteinase in the MCTC type of human mast cell, J. Immunol, 145, 2652, 10.4049/jimmunol.145.8.2652
Irani, 1991, Human mast cell carboxypeptidase. Selective localization to MCTC cells, J. Immunol, 147, 247, 10.4049/jimmunol.147.1.247
Vanderslice, 1990, Human mast cell tryptase: multiple cDNAs and genes reveal a multigene serine protease family, Proc. Natl. Acad. Sci. USA, 87, 3811, 10.1073/pnas.87.10.3811
Katz, 1985, Heterogeneity of mammalian mast cells differentiated in vivoin vitro, J. Allergy Clin. Immunol, 76, 250, 10.1016/0091-6749(85)90638-4
Li, 2014, Distinct cellular origins for serotonin-expressing and enterochromaffin-like cells in the gastric corpus, Gastroenterology, 146, 754, 10.1053/j.gastro.2013.11.048
von Stebut, 2003, Early macrophage influx to sites of cutaneous granuloma formation is dependent on MIP-1α/β released from neutrophils recruited by mast cell-derived TNFα, Blood, 101, 210, 10.1182/blood-2002-03-0921
Kushnir-Sukhov, 2007, Human mast cells are capable of serotonin synthesis and release, J. Allergy Clin. Immunol, 119, 498, 10.1016/j.jaci.2006.09.003
Lowman, 1988, Human mast cell heterogeneity: histamine release from mast cells dispersed from skin, lung, adenoids, tonsils, and colon in response to IgE-dependent and nonimmunologic stimuli, J. Allergy Clin. Immunol, 81, 590, 10.1016/0091-6749(88)90199-6
Rudich, 2012, Mast cell adenosine receptors function: a focus on the A3 adenosine receptor and inflammation, Front. Immunol, 3, 134, 10.3389/fimmu.2012.00134
Zhong, 2003, Activation of murine lung mast cells by the adenosine A3 receptor, J. Immunol, 171, 338, 10.4049/jimmunol.171.1.338
Tilley, 2000, Adenosine and inosine increase cutaneous vasopermeability by activating A3 receptors on mast cells, J. Clin. Invest, 105, 361, 10.1172/JCI8253
Sereda, 2011, Adenosine potentiates human lung mast cell tissue plasminogen activator activity, J. Immunol, 186, 1209, 10.4049/jimmunol.1001563
Gomez, 2011, Disparity in FcɛRI-induced degranulation of primary human lung and skin mast cells exposed to adenosine, J. Clin. Immunol, 31, 479, 10.1007/s10875-011-9517-7
Ujike, 1999, Modulation of immunoglobulin (Ig)E-mediated systemic anaphylaxis by low-affinity Fc receptors for IgG, J. Exp. Med, 189, 1573, 10.1084/jem.189.10.1573
Takai, 1996, Augmented humoral and anaphylactic responses in FcγRII-deficient mice, Nature, 379, 346, 10.1038/379346a0
Hazenbos, 1996, Impaired IgG-dependent anaphylaxis and Arthus reaction in FcγRIII (CD16) deficient mice, Immunity, 5, 181, 10.1016/S1074-7613(00)80494-X
Dombrowicz, 1997, Absence of FcɛRI α chain results in upregulation of FcγRIII-dependent mast cell degranulation and anaphylaxis. Evidence of competition between FcɛRI and FcγRIII for limiting amounts of FcR β and γ chains, J. Clin. Invest, 99, 915, 10.1172/JCI119256
Coleman, 1981, The number and affinity of IgE receptors on dispersed human lung mast cells, Immunology, 44, 859
Sellge, 2014, Interferon-γ regulates growth and controls Fcγ receptor expression and activation in human intestinal mast cells, BMC Immunol, 15, 27, 10.1186/1471-2172-15-27
Helm, 1988, The mast cell binding site on human immunoglobulin E, Nature, 331, 180, 10.1038/331180a0
Tkaczyk, 2002, Activation of human mast cells through the high affinity IgG receptor, Mol. Immunol, 38, 1289, 10.1016/S0161-5890(02)00077-9
Zhao, 2006, FcγRIIa, not FcγRIIb, is constitutively and functionally expressed on skin-derived human mast cells, J. Immunol, 177, 694, 10.4049/jimmunol.177.1.694
Trivedi, 2009, Human subjects are protected from mast cell tryptase deficiency despite frequent inheritance of loss-of-function mutations, J. Allergy Clin. Immunol, 124, 1099, 10.1016/j.jaci.2009.07.026
Befus, 1982, Mucosal mast cells. I. Isolation and functional characteristics of rat intestinal mast cells, J. Immunol, 128, 2475, 10.4049/jimmunol.128.6.2475