Postoperative radiotherapy alone is as effective as postoperative chemoradiotherapy in patients with pT4aN0 gingival cancer with negative surgical margins

Clinical and Translational Radiation Oncology - Tập 41 - Trang 100641 - 2023
Chiung-Chen Fang1,2, He-Yuan Hsieh3, Wen-Cheng Chen2, Miao-Fen Chen2, Chia-Hsuan Lai2, Yu-Yen Chen2, Yao-Te Tsai4, Shu-Ling Tzeng5,6
1Institute of Medicine, Chung-Shan Medical University, Taichung, Taiwan
2Department of Radiation Oncology, Chang Gung Memorial Hospital, Chiayi, Taiwan
3Department of Radiation Oncology, Taichung Veterans General Hospital, Taichung, Taiwan
4Department of Otolaryngology – Head and Neck Surgery, Chang Gung Memorial Hospital, Chiayi, Taiwan
5Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan
6Department of Medical Research, Chung Shan Medical University Hospital, Taichung, Taiwan

Tài liệu tham khảo

Cancer registry annual report. Taiwan; 2019. Cooper, 2004, Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck, N Engl J Med, 350, 1937, 10.1056/NEJMoa032646 Bernier, 2004, Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer, N Engl J Med, 350, 1945, 10.1056/NEJMoa032641 National Comprehensive Cancer Network [internet]. NCCN clinical practice guidelines in oncology: Head and neck cancers. version 2, https://www.nccn.org/professionals/physician_gls/pdf/head-and-neck.pdf; 2022. Fives, 2017, Impact of mandibular invasion on prognosis in oral squamous cell carcinoma four centimeters or less in size, Laryngoscope, 127, 849, 10.1002/lary.26211 Ebrahimi, 2011, The prognostic and staging implications of bone invasion in oral squamous cell carcinoma, Cancer, 117, 4460, 10.1002/cncr.26032 Bernier, 2005, Defining risk levels in locally advanced head and neck cancers: A comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (# 9501), Head Neck, 27, 843, 10.1002/hed.20279 Cheng, 2016, Clinical implications of recent exodontia before diagnosis of gingival squamous cell carcinoma: A new classification, Head Neck, 38, 339, 10.1002/hed.23896 Yoshida, 2018, The prognostic implications of bone invasion in gingival squamous cell carcinoma, Anticancer Res, 38, 955 Namin, 2020, Implications of tumor size, subsite, and adjuvant therapy on outcomes in pT4aN0 oral cavity carcinoma, Otolaryngol Head Neck Surg, 162, 683, 10.1177/0194599820904679 Trifiletti, 2017, Beyond positive margins and extracapsular extension: Evaluating the utilization and clinical impact of postoperative chemoradiotherapy in resected locally advanced head and neck cancer, J Clin Oncol, 35, 1550, 10.1200/JCO.2016.68.2336 Ariyoshi, 2008, Epidemiological study of malignant tumors in the oral and maxillofacial region: Survey of member institutions of the Japanese Society of Oral and Maxillofacial Surgeons, 2002, Int J Clin Oncol, 13, 220, 10.1007/s10147-007-0756-9