Post-traumatic inflammation following spinal cord injury
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Acarin L et al. Neuronal, astroglial and microglial cytokine expression after an excitotoxic lesion in the immature rat brain. Eur J Neurosci 2000; 12: 3505–3520.
Bartholdi D, Schwab ME . Expression of pro-inflammatory cytokine and chemokine mRNA upon experimental spinal cord injury in mouse: an in situ hybridization study. Eur J Neurosci 1997; 9: 1422–1438.
Bethea JR et al. Traumatic spinal cord injury induces nuclear factor-kappaB activation. J Neurosci 1998; 18: 3251–3260.
Bethea JR et al. Systemically administrated interleukin-10 reduces tumor necrosis factor-α production and significantly improves functional recovery following traumatic spinal cord injury in rats. J Neurotrauma 1999; 16: 851–863.
Hayashi M et al. Sequential mRNA expression for immediate early genes, cytokines, and neurotrophins in spinal cord injury. J Neurotrauma 2000; 17: 203–218.
Klusman I, Schwab ME . Effects of pro-inflammatory cytokines in experimental spinal cord injury. Brain Res 1997; 762: 173–184.
Popovich PG et al. Cellular inflammatory response after spinal cord injury in Sprague–Dawley and Lewis rats. J Comp Neurol 1997; 377: 443–464.
Schwab ME, Bartholdi D . Degeneration and regeneration of axons in the lesioned spinal cord. Physiol Rev 1996; 76: 319–370.
Schnell L et al. Acute inflammatory responses to mechanical lesions in the CNS: differences between brain and spinal cord. Eur J Neurosci 1999a; 11: 3648–3658.
Schnell L et al. Cytokine-induced acute inflammation in the brain and spinal cord. J Neuropathol Exp Neurol 1999b; 55: 245–254.
Grimpe B, Silver J . The extracellular matrix in axon regeneration. Prog Brain Res 2002; 137: 333–349.
Jones LL, Tuszynski MH . Spinal cord injury expression of keratan sulfate proteoglycans by macrophages, reactive microglia, and oligodendrocyte progenitors. J Neurosci 2002; 22: 4611–4624.
Zhang Y et al. Tenascin-C expression and axonal sprouting following injury to the spinal dorsal columns in the adult rat. J Neurosci Res 1997; 49: 433–450.
Popovich PG . Immunonological regulation of neuronal degeneration and regeneration in the injured spinal cord. Prog Brain Res 2000; 128: 43–58.
Beattie MS, Bresnahan JC . Cell death, repair, and recovery of function after spinal cord injury in rats. In: Kalb RG, Strittmatter SM (eds). Neurobiology of Spinal Cord Injury. Humana Press Inc.: Totowa, NJ 2000.
Liu XZ et al. Neuronal and glial apoptosis after traumatic spinal cord injury. J Neuosci 1997; 17: 5395–5306.
Marmarou A et al. Traumatic brain tissue acidosis: experimental and clinical studies. Acta Neurochir Suppl 1993; 57: 160–164.
Segal JL et al. Circulating levels of IL-2R, ICAM-1, and IL-6 in spinal cord injuries. Arch Phys Med Rehabil 1997; 78: 44–47.
Beattie MS et al. Cell death and plasticity after experimental spinal cord injury. Prog Brain Res 2000; 128: 9–21.
Basso DM et al. Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transsection. Exp Neurol 1996; 139: 244–256.
Basso DM et al. MASCIS evaluation of open field locomotor scores: effects of experience and teamwork reliability. J Neurotrauma 1996; 13: 343–359.
Constantini S, Young W . The effects of methylprednisolone and the ganglioside GM1 on acute spinal cord injury in rats. J Neurosurg 1994; 80: 97–111.
Gruner JA . A monitored contusion model of spinal cord injury in the rat. J Neurotrauma 1992; 9: 123–128.
Behrmann DL et al. Spinal cord injury produced by consistent mechanical displacement of the cord in rats: behavioral and histologic analysis. J Neurotrauma 1992; 9: 197–217.
Bresnahan JC . A behavioral and anatomical analysis of spinal cord injury produced by a feedback-controlled impaction device. Exp Neurol 1987; 95: 548–570.
Casha S et al. Oligodendroglial apoptosis occurs along degenerating axons and is associated with Fas and p75 expression following spinal cord injury in the rat. Neuroscience 2001; 103: 203–218.
Abraham KE et al. The role of kainic acid/AMPA and metabotropic glutamate receptors in the regulation of opiod mRNA expression and the onset of pain-related behaviour following excitotoxic spinal cord injury. Neuroscience 2001; 104: 836–874.
Plunkett J et al. Effects of interleukin-10 on pain behavior and gene expression following excititoxic spinal cord injury in the rat. Exp Neural 2001; 168: 144–154.
Beattie MS et al. ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury. Neuron 2002; 36: 375–386.
Joshi M, Fehlings M . Development and characterization of a novel, graded model of clip compressive spinal cord injury in the mouse: Part 1. Clip design, behavioral outcome, and histopathology. J Neurotrauma 2002; 19: 175–190.
Joshi M, Fehlings M . Development and characterization of a novel, graded model of clip compressive spinal cord injury in the mouse: Part 2. Quantitative neuroanatomical assessment and analysis of the relationship between axonal tracts, residual tissue, and locomotor recovery. J Neurotrauma 2002; 19: 191–203.
Stokes BT, Jakeman LB . Experimental modeling of human spinal cord injury: a model that crosses the species barrier and mimics the spectrum of human cytopathology. Spinal Cord 2002; 40: 101–109.
Beal MF . Energetics in the pathogenesis of neuro-degenerative diseases. Trends Neurosci 2000; 23: 298–304.
Davies SJ, Silver J . Adult axon regeneration in adult CNS white matter. Trends Neurosci 1998; 21: 515.
Hausmann ON et al. Spinal cord injury induces expression of RGS7 in microglia/macrophages in rats. Eur J Neurosci 2002; 15: 602–612.
Noble LJ et al. Disruption and time course of protein extravasation in the rat spinal cord after contusive injury. Brain Res 1989; 482: 57–66.
Pan W, Kastin AJ . Increase in TNFalpha transport after SCI is specific for time, region, and type of lesion. Exp Neurol 2001; 170: 357–363.
Mautes AE et al. Vascular events after spinal cord injury: contribution to secondary pathogenesis. Phys Ther 2000; 80: 673–687.
Tator CH, Koyanagi I . Vascular mechanisms in the pathophysiology of human spinal cord injury. J Neurosurg 1997; 86: 483–492.
Saikumar P et al. Mechanisms of cell death in hypoxia/reoxygenation injury. Oncogene 1998; 17: 3341–3349.
Mills CD et al. Changes in metabotropic glutamate receptor expression following spinal cord injury. Exp Neurol 2001; 170: 244–257.
Ha BK et al. Kainate-induced excitotoxicity is dependent upon extracellular potassium concentrations that regulate the activity of AMPA/KA type receptors. J Neurochem 2002; 83: 934–945.
Mills CD et al. Involvement of metabotropic glutamate receptors in excitatory amino acid and GABA release following spinal cord injury in rat. J Neurochem 2001; 79: 835–848.
Chu GK et al. Calcium and neuronal death in spinal neurons. In: Kalb RG, Strittmatter SM (eds). Neurobiology of Spinal Cord Injury. Humana Press Inc.: Totowa, NJ 2000.
Regan RF, Choi DW . Glutamate neurotoxicity in spinal cord cell culture. Neuroscience 1991; 43: 585–591.
Vera-Portocarrero LP et al. Rapid changes in expression of glutamate transporters after spinal cord injury. Brain Res 2002; 927: 104–110.
Regan RF . The vulnerability of spinal cord neurons to excitotoxic injury: comparison with cortical neurons. Neurosci Lett 1996; 213: 9–12.
Choi DW . Glutamate receptors and the induction of excitotoxic neuronal cell death. Curr Opin Neurobiol 1996; 6: 667–672.
Jansco G et al. Neurotoxin induced nerve cell degeneration: possible involvement of calcium. Brain Res 1984; 295: 211–216.
Aizenman E et al. Oxygen free radicals regulate NMDA receptor function via a redox modulatory site. Neuron 1990; 5: 841–846.
Dalkara T et al. Constitutive nitric oxide synthase and ischemic/excitotoxic brain injury. In: Ruffolo RR et al (eds). Inflammatory Cells and Mediators in CNS Diseases. New Academic Publishers: Amsterdam 1999.
Lipton SA et al. A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds. Nature 1993; 364: 626–631.
Nakahara S et al. Changes in nitric oxide and expression of nitric oxide synthase in spinal cord after traumatic injury in rats. J Neurotrauma 2002; 11: 1467–1474.
Bao F, Liu D . Peroxynitrite generated in the rat spinal cord induces neuron death and neurological deficits. Neuroscience 2002; 115: 839–849.
Dawson VL et al. Mechanisms of nitric oxide-mediated neurotoxicity in primary cortical cultures. J Neurosci 1993; 13: 2651–2661.
Brewer GJ, Wallimann T . Protective effects of the energy precursor creatine against toxicity of glutamate and beta-amyloid in rat hippocampal neurons. J Neurochem 2000; 74: 1968–1978.
Hausmann ON et al. Protective effects of oral creatine supplementation prior to spinal cord injury in rats. Spinal Cord 2002; 40: 449–456.
Taoka Y, Okajima K . Role of leucocytes in spinal cord injury in rats. J Neurotrauma 2000; 17: 219–229.
Carlson SL et al. Acute inflammatory response in spinal cord following impact injury. Exp Neurol 1998; 151: 77–88.
Chatzipanteli K et al. Post-traumatic hypothermia reduces polymorphnuclear leucocyte accumulation following spinal cord injury in rats. J Neurotrauma 2000; 17: 321–332.
Watanabe T et al. Differential activation of microglia after experimental spinal cord injury. J Neurotrauma 1999; 16: 255–265.
Shuman SL et al. Apoptosis of microglia and oligo-dendrocytes after spinal cord injury in rats. J Neurosci Res 1997; 50: 798–808.
Schwartz M . Autoimmune involvement in CNS trauma is beneficial if well controlled. Prog Brain Res 2000; 128: 259–263.
Rapalino O et al. Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats. Nat Med 1998; 4: 814–821.
Hauben E et al. Autoimmune T cells as potential neuroprotective therapy for spinal cord injury. Lancet 2000; 354: 286–287.
Nevo U et al. Diffusion anisotrophy MRI for quantitative assessment of recovery in injured rat spinal cord. Magn Reson Med 2001; 45: 1–9.
Stichel CC, Müller HW . The CNS lesion scar: new vistas on an old regeneration barrier. Cell Tissue Res 1998; 249: 1–9.
Fawcett JW . Spinal cord repair: from experimental models to human application. Spinal Cord 1998; 36: 811–817.
Fawcett JW, Asher RA . The glial scar and central nervous system repair. Brain Res Bull 1999; 49: 377–391.
Fitch MT, Silver J . Glial cell extracellular matrix: boundaries for axon growth in the development and regeneration. Cell Tissue Res 1997a; 290: 379–384.
Goss JR . Astrocytes are the major source nerve growth factor upregulation following traumatic brain injury in the rat. Exp Neurol 1998; 149: 301–309.
Liesi P et al. Laminin is induced in astrocytes of the adult brain by injury. EMBO J 1984; 3: 683–686.
Davies SJ et al. Regeneration of adult axons in white matter tracts of the central nervous system. Nature 1997; 390: 680–683.
Davies SJ et al. Robust regeneration of adult sensory axons in degenerating white matter of the adult rat spinal cord. J Neurosci 1999; 19: 5810–5822.
Majno G et al. Apoptosis, oncosis, and necrosis. An overview of cell death. Am J Pathol 1995; 146: 3–15.
Crowe MJ et al. Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys. Nat Med 1997; 3: 73–76.
Springer JE et al. Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury. Nat Med 1999; 5: 943–946.
Baker SJ, Reddy EP . Modulation of life and death by the TNF receptor superfamily. Oncogene 1998; 17: 3261–3270.
Li GL et al. Changes of Fas and Fas ligand immuno-reactivity after compression trauma to rat spinal cord. Acta Neuropathol 2000; 100: 75–81.
Zurita M et al. Presence and significance of CD-95 (Fas/APO1) expression after spinal cord injury. J Neurosurg (Spine) 2001; 94: 257–264.
Lee YB et al. Role of tumor necrosis factor-α in neuronal and glial apoptosis after spinal cord injury. Exp Neurol 2000; 166: 190–195.
Wada S . Apoptosis following spinal cord injury in rats and preventative effects of N-methyl-D-aspartate receptor agonist. J Neurosurg (Spine 1) 1999; 91: 98–104.
Rabchevsky AG et al. Basic fibroblast growth factor (bFGF) enhances tissue sparing and functional recovery following moderate spinal cord injury. J Neurotrauma 1999; 16: 817–830.
Zurita M et al. Effects of dexamethasone on apoptosis-related cell death after spinal cord injury. J Neurosurg (Spine) 2002; 96: 83–89.
Wrathall JR et al. Myelin gene expression after experimental contusive spinal cord injury. J Neurosci 1998; 18: 8780–8793.
Purves D et al. Intracellular signal transduction. In: Purves D et al (eds). Neuroscience. 2nd ed. Sinauer Associates: Sunderland, MA 2001.
O'Farrell AM et al. IL-10 inhibits macrophage activation and proliferation by distinct signalling mechanisms: evidence for Stat3-dependent and -independent pathways. EMBO J 1998; 17: 1006–1013.
Dietrich WD et al. Postischemic hypothermia and IL-10 treatment provide long-lasting neuroprotection of CA1 hippocampus following transient global ischemia in rats. Exp Neurol 1999; 158: 444–450.
Knoblauch SM et al. lnterleukin-10 improves outcome and alters proinflammatory cytokine expression after experimental traumatic brain injury. Exp Neurol 1998; 153: 143–151.
Bruce AJ et al. Alterated neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors. Nat Med 1996; 2: 788–794.
Holmin S et al. Intracerebral administration of interleukin-1b and induction of inflammation, apoptosis, and vasogenic edema. J Neurosurg 2000, 92: 108–120.
Streit WJ et al. Comparative evaluation of cytokine profiles and reactive gliosis supports a critical role for interleukin-6 in neuron–glia signaling during regeneration. J Neurosci Res 2000; 61: 10–20.
Lacroix S et al. Delivery of hyper-interleukin-6 to the injured signal cord increases neutrophil and macrophage infiltration and inhibits axonal growth. J Comp Neurol 2002; 454: 213–228.
Pan JZ et al. Cytokine activity contributes to induction of inflammatory cytokine mRNAs in spinal cord following contusion. J Neurosci Res 2002; 68: 315–322.
Wang CX et al. Increase of interleukin-1B mRNA and protein in the spinal cord following experimental traumatic injury in the rat. Brain Res 1997; 759: 190–196.
Anthony DC et al. Age-related effects of interleukin 1B on polymorphnuclear neutrophil-dependent increases in blood–brain barrier permeability in rats. Brain 1997; 120: 435–444.
Benzing T et al. Upregulation of RGS7 may contribute to tumor necrosis factor induced changes in central nervous function. Nat Med 1999; 5: 913–918.
Bradburry EJ et al. Chondroitinase ABC promotes functional recovery after spinal cord injury. Nature 2002; 416: 636–640.
Birkedal-Hansen H et al. Matrix metalloproteases: a review. Crit Rev Oral Biol Med 1993; 4: 197–250.
Noble LJ et al. Matrix metalloproteases limit functional recovery after spinal cord injury by modulation of early vascular events. J Neurosci 2002; 22: 7526–7535.
Xu J et al. Glucocorticoid receptor-mediated suppression of activator protein-1 activation and metalloproteinase expression after spinal cord injury. J Neurosci 2001; 2: 502–511.
Guang C et al. Beneficial effects of modest hypothermia on locomotor function and histopathological damage following contusion-induced spinal cord injury in rats. J Neurosurg (Spine1) 2000; 93: 85–93.
Stevens JD, Tetzlaff W . Strategies for spinal cord repair. In: Kalb RG, Strittmatter SM (eds). Neurobiology of Spinal Cord Injury. Humana Press Inc.: Totowa, NJ 2000.
Behrmann DL et al. Modeling spinal cord injury in the rat: neuroprotection and enhanced recovery with methylprednisolone and YM-14673. Exp Neurol 1994; 126: 61–75.
Fitch MT, Silver J . Activated macrophages and the blood–brain barrier: inflammation after CNS injury leads to increase in putative molecules. Exp Neurol 1997b; 148: 587–603.
Krautstrunk M et al. Increased expression of the putative axon growth-repulsive extracellular matrix molecule, keratan sulphate proteoglycan, following traumatic injury of the adult rat spinal cord. Acta Neuropathol 2002; 104: 592–600.
Schwartz M . Protective autoimmunity as a T-cell response to central nervous system trauma: prospects for therapeutic vaccines. Prog Neurobiol 2001; 65: 489–496.