Post-polypectomy bleeding after colonoscopy on uninterrupted aspirin/non steroideal antiflammatory drugs: Systematic review and meta-analysis

Winawer, 1993, Prevention of colorectal cancer by colonoscopic polypectomy. The National Polyp Study Workgroup, N Engl J Med, 329, 1977, 10.1056/NEJM199312303292701 Wexner, 2001, A prospective analysis of 13,580 colonoscopies. Reevaluation of credentialing guidelines, Surg Endosc, 15, 251, 10.1007/s004640080147 Bowles, 2004, Prospective study of colonoscopy practice in the UK today: are we adequately prepared for national colorectal cancer screening tomorrow?, Gut, 53, 277, 10.1136/gut.2003.016436 Sieg, 2001, Prospective evaluation of complications in outpatient GI endoscopy: a survey among German gastroenterologists, Gastrointest Endosc, 53, 620, 10.1067/mge.2001.114422 Sawhney, 2008, Risk factors for severe delayed postpolypectomy bleeding, Endoscopy, 40, 115, 10.1055/s-2007-966959 Amato, 2016, Early and delayed complications of polypectomy in a community setting: the Spoc prospective prophylactic trial, Dig Liv Dis, 48, 43, 10.1016/j.dld.2015.09.007 Zhang, 2014, Assessment of risk factors for delayed colonic post polypectomy hemorrhage: a study of 15,553 polypectomies from 2005 to 2013, PLoS One, 9, 1 Kim, 2014, What can be the criteria of outpatient-based endoscopic resection for colon polyp?, World J Gastrointest Endosc, 6, 493, 10.4253/wjge.v6.i10.493 Choung, 2014, Incidence and risk factors of delayed postpolypectomy bleeding: a retrospective cohort study, Clin Gastroenterol, 48, 784, 10.1097/MCG.0000000000000027 Manocha, 2012, Bleeding risk after invasive procedures in aspirin/NSAID users: polypectomy study in Veterans, Am J Med, 125, 1222, 10.1016/j.amjmed.2012.05.030 Gimeno-Garcia, 2012, Incidence and predictors of postpolypectomy bleeding in colorectal polyps larger than 10mm, Eur J Gastroenterol Hepatol, 24, 520, 10.1097/MEG.0b013e328350fcdc Hui, 2004, Risk of colonsocpic polypectomy bleeding with anticoagulants and antiplatelet agents: analysis of 1657 cases, Gastrointest Endosc, 59, 44, 10.1016/S0016-5107(03)02307-1 Veitch, 2016, Endoscopy in patients on antiplatelet or anticoagulant therapy, including direct oral anticoagulants: British Society of Gastroenterology (BSG) and European Society of Gastrointestinal Endoscopy (ESGE) guidelines, Endoscopy, 48, 1 Shiffman, 1994, Risk of bleeding after endoscopic biopsy or polypectomy in patients taking aspirin or other NSAIDS, Gastrointest Endosc, 40, 458, 10.1016/S0016-5107(94)70210-1 Yousfi, 2004, Postpolypectomy lower gastrointestinal bleeding: potential role of aspirin, Am J Gastroenterol, 99, 1785, 10.1111/j.1572-0241.2004.30368.x Pan, 2012, The role of aspirin in post-polypectomy bleeding. A retrospective survey, BMC Gastroenterol, 12, 138, 10.1186/1471-230X-12-138 Metz, 2011, Factors that predict bleeding following endoscopic mucosal resection of large colonic lesions, Endoscopy, 43, 506, 10.1055/s-0030-1256346 Soni A. Aspirin use among the adult U.S. non institutionalized population, with and without indicators of heart disease, 2005. Statistical Brief #129. Agency for Healthcare Research and Quality, Medical Expenditure Panel Survey, available at: http://meps.ahrq.gov/mepsweb/data_files/publications/st179/stat179.pdf. [Accessed December 2016]. FitzGerald, 1983, Endogenous biosynthesis of prostacyclin and thromboxane and platelet function during chronic administration of aspirin in man, J Clin Invest, 71, 676, 10.1172/JCI110814 Patrono, 2009, Low-dose aspirin, coxibs, and other NSAIDS: a clinical mosaic emerges, Mol Interv, 9, 31, 10.1124/mi.9.1.8 Schulman, 2010, Definition of major bleeding in clinical investigations of antihemostatic medicinal products in surgical patients, J Thromb Haemost, 8, 202, 10.1111/j.1538-7836.2009.03678.x Moher, 2009, The PRISMA group. Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement, PLoS Med, 6, 10.1371/journal.pmed.1000097 Wells GA, Shea B, O’Connell D, Dae Hun Kwon, Kang Hun Koh, Ji Youn Sohn, et al. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. http://wwwohrica/programs/clinical_epidemiology/oxfordhtml. [Accessed December 2016]. Higgins, 2003, Measuring inconsistency in meta-analyses, BMJ, 327, 557, 10.1136/bmj.327.7414.557 Egger, 1997, Bias in meta-analysis detected by a simple, graphical test, BMJ, 315, 629, 10.1136/bmj.315.7109.629 Duval, 2000, A nonparametric “trim and fill” method of accounting for publication bias in meta-analysis, JASA, 95, 89 Wu, 2013, Risk factors for delayed postpolypectomy bleeding: how to minimize your patients’ risk, Int J Colorectal Dis, 28, 1127, 10.1007/s00384-013-1661-5 Kim, 2006, Risk factors for immediate postpolypectomy bleeding of the colon: a multicenter study, Am J Gastroenterol, 101, 1333, 10.1111/j.1572-0241.2006.00638.x Park, 2015, Comparison of clipping with and without epinephrine injection for the prevention of post-polypectomy bleeding in pedunculated colon polyps, J Gastroenterol Hepatol, 30, 1499, 10.1111/jgh.12994 Bahin, 2016, Prediction of clinically significant bleeding following wide-field endoscopic resection of large sessile and laterally spreading colorectal lesions: a clinical risk score, Am J Gastroenterol, 111, 1115, 10.1038/ajg.2016.235 Burgess, 2014, Risk factors for intraprocedural and clinically significant delayed bleeding after wide-field endoscopic mucosal resection of large colonic lesions, Clin Gastroenterol Hepatol, 12, 651, 10.1016/j.cgh.2013.09.049 Beppu, 2014, Timing for resuming antithrombotic agents and risk factors for delayed bleeding after endoscopic resection of colorectal tumors, Gastroenterol Res Pract, 2014, 825179, 10.1155/2014/825179 Anderson, 2009, Management of antithrombotic agents for endoscopic procedures, Gastrointest Endosc, 70, 1060, 10.1016/j.gie.2009.09.040 Cotton, 1996, 168 Shalman, 2015, Systematic review with meta-analysis: the risk of gastrointestinal haemorrhage post-polypectomy in patients receiving anti-platelet, anti-coagulant and/or thienopyridine medications, Aliment Pharmacol Ther, 42, 949, 10.1111/apt.13367 Moon, 2014, Only the size of resected polyps is an independent risk factor for delayed postpolypectomy hemorrhage: a 10-year single-center case-control study, Ann Coloproctol, 30, 182, 10.3393/ac.2014.30.4.182 Grossman, 2010, Antiplatelet medications increase the risk of post-polypectomy bleeding, Gastrointest Endosc, 71, 10.1016/j.gie.2010.03.126 Biondi-Zoccai, 2006, A systematic review and meta-analysis on the hazards of discontinuing or not adhering to aspirin among 50,279 patients at risk for coronary artery disease, Eur Heart J, 27, 2667, 10.1093/eurheartj/ehl334