Polymorphisms of endothelial nitric oxide synthase gene in systolic heart failure: An haplotype analysis

Rossi, 2003, The T-786C endothelial nitric oxide synthase genotype is a novel risk factor for coronary artery disease in Caucasian patients of the GENICA study, J. Am. Coll. Cardiol., 41, 930, 10.1016/S0735-1097(02)03012-7 McNamara, 2003, Effect of the Asp298 variant of endothelial nitric oxide synthase on survival for patients with congestive heart failure, Circulation, 107, 1598, 10.1161/01.CIR.0000060540.93836.AA Cruz-Gonzalez, 2009, Association between -T786C NOS3 polymorphism and resistant hypertension: a prospective cohort study, BMC Cardiovasc. Disord., 9, 35, 10.1186/1471-2261-9-35 Mohan, 1996, Myocardial contractile response to nitric oxide and cGMP, Circulation, 93, 1223, 10.1161/01.CIR.93.6.1223 Förstermann, 1994, Nitric oxide synthase isozymes. Characterization, purification, molecular cloning and functions, Hypertension, 23, 1121, 10.1161/01.HYP.23.6.1121 Song, 2003, Genotype-specific influence on nitric oxide synthase gene expression, protein concentrations, and enzyme activity in cultured human endothelial cells, Clin. Chem., 49, 847, 10.1373/49.6.847 Senthil, 2005, Genotype-dependent expression of endothelial nitric oxide synthase (eNOS) and its regulatory proteins in cultured endothelial cells, DNA Cell Biol., 24, 218, 10.1089/dna.2005.24.218 Marsden, 1993, Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene, J. Biol. Chem., 268, 17478, 10.1016/S0021-9258(19)85359-0 Dosenko, 2006, Allelic polymorphism of endothelial NO-synthase gene and its functional manifestations, Acta Biochim. Pol., 53, 299, 10.18388/abp.2006_3342 Doshi, 2010, A promoter polymorphism of the endothelial nitric oxide synthase gene is associated with reduced mRNA and protein expression in failing human myocardium, J. Card. Fail., 16, 314, 10.1016/j.cardfail.2009.12.013 Casas, 2004, Endothelial nitric oxide synthase genotype and ischemic heart disease: meta-analysis of 26 studies involving 23028 subjects, Circulation, 109, 1359, 10.1161/01.CIR.0000121357.76910.A3 Tsukada, 1998, Evidence of association of the ecNOS gene polymorphism with plasma NO metabolite levels in humans, Biochem. Biophys. Res. Commun., 245, 190, 10.1006/bbrc.1998.8267 Wang, 1996, A smoking-dependent risk of coronary artery disease associated with a polymorphism of the endothelial nitric oxide synthase gene, Nat. Med., 2, 41, 10.1038/nm0196-41 Jemaa, 2007, Association of a 27-bp repeat polymorphism in intron 4 of endothelial constitutive nitric oxide synthase gene with myocardial infarction in Tunisian patients, Clin. Chem. Lab. Med., 45, 1476, 10.1515/CCLM.2007.312 Small, 2008, Genetic variation within the beta1-adrenergic receptor gene results in haplotype-specific expression phenotypes, J. Cardiovasc. Pharmacol., 51, 106, 10.1097/FJC.0b013e31815a958f Metzger, 2011, Endothelial nitric oxide synthase gene haplotypes affect nitrite levels in black subjects, Pharmacogenomics J., 11, 393, 10.1038/tpj.2010.52 Tanus-Santos, 2001, Effects of ethnicity on the distribution of clinically relevant endothelial nitric oxide variants, Pharmacogenetics, 11, 719, 10.1097/00008571-200111000-00011 Buraczynska, 2004, Endothelial nitric oxide synthase gene intron 4 polymorphism in patients with end-stage renal disease, Nephrol. Dial. Transplant., 19, 2302, 10.1093/ndt/gfh077 Hedrick, 1987, Gametic disequilibrium measures: proceed with caution, Genetics, 117, 331, 10.1093/genetics/117.2.331 Stephens, 2001, A new statistical method for haplotype reconstruction from population data, Am. J. Hum. Genet., 68, 978, 10.1086/319501 Stephens, 2005, Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation, Am. J. Hum. Genet., 76, 449, 10.1086/428594 Sandrim, 2006, Susceptible and protective eNOS haplotypes in hypertensive black and white subjects, Atherosclerosis, 186, 428, 10.1016/j.atherosclerosis.2005.08.003 Velloso, 2010, Endothelial nitric oxide synthase Glu298Asp gene polymorphism in a multi-ethnical population with heart failure and controls, Nitric Oxide, 22, 220, 10.1016/j.niox.2009.12.007 Zakrzewski-Jakubiak, 2008, Ten renin-angiotensin system-related gene polymorphisms in maximally treated Canadian Caucasian patients with heart failure, Br. J. Clin. Pharmacol., 65, 742, 10.1111/j.1365-2125.2007.03091.x McNamara, 2009, Endothelial nitric oxide synthase (NOS3) polymorphisms in African Americans with heart failure: results from the A-HeFT trial, J. Card Fail., 15, 191, 10.1016/j.cardfail.2008.10.028 Saraiva, 2006, Nitric oxide signaling in the cardiovascular system: implications for heart failure, Curr. Opin. Cardiol., 21, 221, 10.1097/01.hco.0000221584.56372.dc Jones, 2003, Endothelial nitric oxide synthase overexpression attenuates congestive heart failure in mice, Proc. Natl. Acad. Sci. USA, 100, 4891, 10.1073/pnas.0837428100 Uchiyama, 2002, Nitric oxide induces caspase-dependent apoptosis and necrosis in neonatal rat cardiomyocytes, J. Mol. Cell. Cardiol., 24, 1049, 10.1006/jmcc.2002.2045 Brown, 2007, Nitric oxide and mitocondrial respiration in the heart, Cardiovasc. Res., 75, 283, 10.1016/j.cardiores.2007.03.022 Hare, 1995, Nitric oxide inhibits the positive inotropic response to beta-adrenergic stimulation in humans with left ventricular dysfunction, Circulation, 92, 2198, 10.1161/01.CIR.92.8.2198 Alfadhli, 2011, Endothelial nitric oxide synthase gene haplotype association with systemic lupus erythematosus, Lupus, 20, 700, 10.1177/0961203310395980 Holla, 2008, Haplotype analysis of the endothelial nitric oxide synthase gene in asthma, Hum. Immunol., 69, 306, 10.1016/j.humimm.2008.03.003