Polymorphisms in genes MTHFR, MTR and MTRR are not risk factors for cleft lip/palate in South Brazil

Murray JC, 2002, Gene/environment causes of cleft lip and/or palate, Clin Genet, 61, 248, 10.1034/j.1399-0004.2002.610402.x

Bender PL, 2000, Genetics of cleft lip and palate, J Pediatr Nurs, 15, 242, 10.1053/jpdn.2000.8148

Goyette P, 1994, Human methylenetetrahydrofolate reductase: isolation of cDNA, mapping and mutation identification, Nat Genet, 7, 195, 10.1038/ng0694-195

Bailey LB, 2000, New standard for dietary folate intake in pregnant women, Am J Clin Nutr, 71, 1304S, 10.1093/ajcn/71.5.1304s

Leclerc D, 1996, Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders, Hum Mol Genet, 5, 1867, 10.1093/hmg/5.12.1867

Leclerc D, 1998, Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria, Proc Natl Acad Sci USA, 95, 3059, 10.1073/pnas.95.6.3059

Wilson A, 1999, A common variant in methionine synthase reductase combined with low cobalamin (vitamin B12) increases risk for spina bifida, Mol Genet Metab, 67, 317, 10.1006/mgme.1999.2879

van der Put NM, 1997, Sequence analysis of the coding region of human methionine synthase: relevance to hyperhomocysteinaemia in neural-tube defects and vascular disease, QJM, 90, 511, 10.1093/qjmed/90.8.511

Doolin MT, 2002, Maternal genetic effects, exerted by genes involved in homocysteine remethylation, influence the risk of spina bifida, Am J Hum Genet, 71, 1222, 10.1086/344209

Sharp L, 2004, Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: a HuGE review, Am J Epidemiol, 159, 423, 10.1093/aje/kwh066

Frosst P, 1995, A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase, Nat Genet, 10, 111, 10.1038/ng0595-111

Khoury MJ, 1987, Maternal cigarette smoking and oral clefts: a population-based study, Am J Public Health, 77, 623, 10.2105/AJPH.77.5.623

Wyszynski DF, 1997, Maternal cigarette smoking and oral clefts: a meta-analysis, Cleft Palate Craniofac J, 34, 206, 10.1597/1545-1569(1997)034<0206:MCSAOC>2.3.CO;2

Lieff S, 1999, Maternal cigarette smoking during pregnancy and risk of oral clefts in newborns, Am J Epidemiol, 150, 683, 10.1093/oxfordjournals.aje.a010071

Tolarova M, 1995, Reduced recurrence of orofacial clefts after periconceptional supplementation with high-dose folic acid and multivitamins, Teratology, 51, 71, 10.1002/tera.1420510205

Itikala PR, 2001, Maternal multivitamin use and orofacial clefts in offspring, Teratology, 63, 79, 10.1002/1096-9926(200102)63:2<79::AID-TERA1013>3.0.CO;2-3

Martinelli M, 2001, C677T variant form at the MTHFR gene and CL/P: a risk factor for mothers?, Am J Med Genet, 98, 357, 10.1002/1096-8628(20010201)98:4<357::AID-AJMG1108>3.0.CO;2-F

Jugessur A, 2003, Exploring the effects of methylenetetrahydrofolate reductase gene variants C677T and A1298C on the risk of orofacial clefts in 261 Norwegian case-parent triads, Am J Epidemiol, 157, 1083, 10.1093/aje/kwg097

Shotelersuk V, 2003, Maternal 677CT/1298AC genotype of the MTHFR gene as a risk factor for cleft lip, J Med Genet, 40, e64, 10.1136/jmg.40.5.e64

Pezzetti F, 2004, Maternal MTHFR variant forms increase the risk in offspring of isolated nonsyndromic cleft lip with or without cleft palate, Hum Mutat, 24, 104, 10.1002/humu.9257

Gaspar DA, 1999, Role of the C677T polymorphism at the MTHFR gene on risk to nonsyndromic cleft lip with/without cleft palate: results from a case-control study in Brazil, Am J Med Genet, 87, 197, 10.1002/(SICI)1096-8628(19991119)87:2<197::AID-AJMG15>3.0.CO;2-M

Vieira AR, 2005, Studies of reduced folate carrier 1 (RFC1) A80G and 5,10-methylenetetrahydrofolate reductase (MTHFR) C677T polymorphisms with neural tube and orofacial cleft defects, Am J Med Genet A, 135, 220, 10.1002/ajmg.a.30705

Rady PL, 2002, Genetic polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) in ethnic populations in Texas; a report of a novel MTHFR polymorphic site, G1793A, Am J Med Genet, 107, 162, 10.1002/ajmg.10122

O'Leary VB, 2002, MTRR and MTHFR polymorphism: link to Down syndrome?, Am J Med Genet, 107, 151, 10.1002/ajmg.10121

Alessio AC, 2004, Polymorphisms in the methylenetetrahydrofolate reductase and methionine synthase reductase genes and homocysteine levels in Brazilian children, Am J Med Genet A, 128, 256, 10.1002/ajmg.a.30108