Polymorphism of Human Cytochrome P450 2D6 and Its Clinical Significance

Springer Science and Business Media LLC - Tập 48 Số 11 - Trang 689-723 - 2009
Shufeng Zhou1
1School of Health Sciences, RMIT University, Melbourne, Australia

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Tài liệu tham khảo

Nebert, 2002, Lancet, 360, 1155, 10.1016/S0140-6736(02)11203-7

Rendic, 2002, Drug Metab Rev, 34, 83, 10.1081/DMR-120001392

Ingelman-Sundberg, 2007, Pharmacol Ther, 116, 496, 10.1016/j.pharmthera.2007.09.004

Kirchheiner, 2007, Biochim Biophys Acta, 1770, 489, 10.1016/j.bbagen.2006.09.019

Tomalik-Scharte, 2008, Pharmacogenomics J, 8, 4, 10.1038/sj.tpj.6500462

Zhou, 2009, Drug Metab Rev, 41, 89, 10.1080/03602530902843483

Alexanderson, 1969, Br Med J, 4, 764, 10.1136/bmj.4.5686.764

Mahgoub, 1977, Lancet, II, 584, 10.1016/S0140-6736(77)91430-1

Eichelbaum, 1979, Eur J Clin Pharmacol, 16, 183, 10.1007/BF00562059

Cascorbi, 2003, Eur J Clin Invest, 33, 17, 10.1046/j.1365-2362.33.s2.3.x

Gardiner, 2006, Pharmacol Rev, 58, 521, 10.1124/pr.58.3.6

Ingelman-Sundberg, 2005, Pharmacogenomics J, 5, 6, 10.1038/sj.tpj.6500285

Zhou, 2008, Curr Drug Metab, 9, 738, 10.2174/138920008786049302

Marechal, 2008, Br J Pharmacol, 153, S82, 10.1038/sj.bjp.0707570

Bock, 1994, Pharmacogenetics, 4, 209, 10.1097/00008571-199408000-00005

Zanger, 2004, Naunyn Schmiedebergs Arch Pharmacol, 369, 23, 10.1007/s00210-003-0832-2

Sachse, 1997, Am J Hum Genet, 60, 284

Bradford, 2002, Pharmacogenomics, 3, 229, 10.1517/14622416.3.2.229

Wang, 1993, Clin Pharmacol Ther, 53, 410, 10.1038/clpt.1993.44

Johansson, 1991, Eur J Clin Pharmacol, 40, 553, 10.1007/BF00279968

Dahl, 1995, J Pharmacol Exp Ther, 274, 516

Aklillu, 1996, J Pharmacol Exp Ther, 278, 441

Gough, 1993, Genomics, 15, 430, 10.1006/geno.1993.1082

Kimura, 1989, Am J Hum Genet, 45, 889

Eichelbaum, 1987, Br J Clin Pharmacol, 23, 455, 10.1111/j.1365-2125.1987.tb03075.x

Heim, 1990, Lancet, 336, 529, 10.1016/0140-6736(90)92086-W

Heim, 1992, Genomics, 14, 49, 10.1016/S0888-7543(05)80282-4

Steen, 1995, Pharmacogenetics, 5, 215, 10.1097/00008571-199508000-00005

Pai, 2004, J Biol Chem, 279, 27383, 10.1074/jbc.M402337200

Gaedigk, 2005, Biochem Biophys Res Commun, 336, 1241, 10.1016/j.bbrc.2005.08.255

Zhang, 2009, Drug Metab Dispos, 37, 1, 10.1124/dmd.108.023663

Nelson, 2004, Pharmacogenetics, 14, 1, 10.1097/00008571-200401000-00001

Eichelbaum, 1975, Naunyn Schmiedebergs Arch Pharmacol, 287, R94

Osikowska-Evers, 1987, Clin Pharmacol Ther, 41, 320, 10.1038/clpt.1987.34

Eichelbaum, 1979, Eur J Clin Pharmacol, 16, 189, 10.1007/BF00562060

Eichelbaum, 1986, Br J Clin Pharmacol, 22, 49, 10.1111/j.1365-2125.1986.tb02879.x

Eichelbaum, 1986, Xenobiotica, 16, 465, 10.3109/00498258609050252

Ebner, 1995, Mol Pharmacol, 48, 1078

Tyndale, 1990, Pharmacol Toxicol, 67, 14, 10.1111/j.1600-0773.1990.tb00774.x

Schellens, 1989, J Pharmacol Exp Ther, 249, 638

Madan, 2003, Drug Metab Dispos, 31, 421, 10.1124/dmd.31.4.421

Zanger, 2007, Pharmacogenomics, 8, 743, 10.2217/14622416.8.7.743

Woolhouse, 1979, Clin Pharmacol Ther, 26, 584, 10.1002/cpt1979265584

Eiermann, 1998, Drug Metab Dispos, 26, 1096

Gonzalez, 1988, Nature, 331, 442, 10.1038/331442a0

Evans, 1980, J Med Genet, 17, 102, 10.1136/jmg.17.2.102

Alvan, 1990, Eur J Clin Pharmacol, 39, 533, 10.1007/BF00316090

Bertilsson, 1992, Clin Pharmacol Ther, 51, 388, 10.1038/clpt.1992.38

Dayer, 1989, Clin Pharmacol Ther, 45, 34, 10.1038/clpt.1989.6

Jacqz-Aigrain, 1993, Pharmacogenetics, 3, 197, 10.1097/00008571-199308000-00004

Schmid, 1985, Clin Pharmacol Ther, 38, 618, 10.1038/clpt.1985.235

Kohler, 1997, Pharmacogenetics, 7, 453, 10.1097/00008571-199712000-00003

Hiroi, 2002, Drug Metab Dispos, 30, 970, 10.1124/dmd.30.9.970

Carcillo, 2003, Clin Pharmacol Ther, 73, 456, 10.1016/S0009-9236(03)00055-9

Mankowski, 1999, Drug Metab Dispos, 27, 1024

Yamazaki, 1994, Mol Pharmacol, 46, 568

Paar, 1997, Eur J Clin Pharmacol, 53, 235, 10.1007/s002280050368

Subrahmanyam, 2001, Drug Metab Dispos, 29, 1146

Paar, 1992, Clin Investig, 70, 708, 10.1007/BF00180294

Wu, 2002, Xenobiotica, 32, 411, 10.1080/00498250110113230

Grond, 2004, Clin Pharmacokinet, 43, 879, 10.2165/00003088-200443130-00004

Yuan, 2002, Drug Metab Dispos, 30, 1311, 10.1124/dmd.30.12.1311

Zhou, 2009, Curr Med Chem, 16, 2661, 10.2174/092986709788681985

Mellstrom, 1981, Drug Metab Dispos, 9, 565

Venkatakrishnan, 2000, J Pharmacol Exp Ther, 293, 343

Venkatakrishnan, 2001, J Clin Pharmacol, 41, 1043, 10.1177/00912700122012634

Nielsen, 1996, J Pharmacol Exp Ther, 277, 1659

Lemoine, 1993, Mol Pharmacol, 43, 827

Venkatakrishnan, 1998, J Clin Pharmacol, 38, 112, 10.1002/j.1552-4604.1998.tb04399.x

Haritos, 2000, Pharmacogenetics, 10, 591, 10.1097/00008571-200010000-00003

Hartter, 2002, Pharm Res, 19, 1034, 10.1023/A:1016478708902

Breyer-Pfaff, 1997, Drug Metab Dispos, 25, 340

Olesen, 2000, Br J Clin Pharmacol, 50, 563, 10.1046/j.1365-2125.2000.00298.x

Margolis, 2000, Drug Metab Dispos, 28, 1187

von Moltke, 1997, Psychopharmacology (Berl), 132, 402, 10.1007/s002130050362

Spigset, 2001, Eur J Clin Pharmacol, 57, 653, 10.1007/s002280100373

Bloomer, 1992, Br J Clin Pharmacol, 33, 521, 10.1111/j.1365-2125.1992.tb04082.x

Obach, 2005, Drug Metab Dispos, 33, 262, 10.1124/dmd.104.002428

Xu, 1999, Br J Clin Pharmacol, 48, 416, 10.1046/j.1365-2125.1999.00023.x

Kobayashi, 1999, Drug Metab Dispos, 27, 763

Ring, 2002, Drug Metab Dispos, 30, 319, 10.1124/dmd.30.3.319

Brachtendorf, 2002, Pharmacol Toxicol, 90, 144, 10.1034/j.1600-0773.2002.900306.x

Stormer, 2000, Drug Metab Dispos, 28, 1168

Koyama, 1996, J Pharmacol Exp Ther, 278, 21

Otton, 1996, Br J Clin Pharmacol, 41, 149, 10.1111/j.1365-2125.1996.tb00173.x

Fogelman, 1999, Neuropsychopharmacology, 20, 480, 10.1016/S0893-133X(98)00113-4

Yoshii, 2000, Life Sci, 67, 175, 10.1016/S0024-3205(00)00613-5

Wojcikowski, 2006, Drug Metab Dispos, 34, 471, 10.1124/dmd.105.006445

Shiraga, 1999, Xenobiotica, 29, 217, 10.1080/004982599238623

Dahl, 1991, Acta Psychiatr Scand, 84, 99, 10.1111/j.1600-0447.1991.tb01428.x

Jerling, 1996, Clin Pharmacol Ther, 59, 423, 10.1016/S0009-9236(96)90111-3

Yasui-Furukori, 2001, Drug Metab Dispos, 29, 1263

Tateishi, 2000, Life Sci, 67, 2913, 10.1016/S0024-3205(00)00874-2

Kudo, 1998, Eur J Clin Pharmacol, 54, 253, 10.1007/s002280050455

Yue, 1997, Eur J Clin Pharmacol, 52, 41, 10.1007/s002280050247

Kirkwood, 1997, Br J Clin Pharmacol, 44, 549, 10.1046/j.1365-2125.1997.t01-1-00626.x

Sanwald, 1996, J Chromatogr B Biomed Appl, 678, 53, 10.1016/0378-4347(95)00446-7

Firkusny, 1995, Biochem Pharmacol, 49, 1777, 10.1016/0006-2952(95)00021-Q

Fischer, 1994, Drug Metab Dispos, 22, 269

Sanwald, 1996, Drug Metab Dispos, 24, 602

Desta, 2002, Drug Metab Dispos, 30, 336, 10.1124/dmd.30.3.336

Kobayashi, 1997, J Pharmacol Exp Ther, 280, 927

Rochat, 1997, Pharmacogenetics, 7, 1, 10.1097/00008571-199702000-00001

Olesen, 1999, Pharmacology, 59, 298, 10.1159/000028333

von Moltke, 2001, Drug Metab Dispos, 29, 1102

von Moltke, 1998, Psychopharmacology (Berl), 140, 293, 10.1007/s002130050770

Greenblatt, 2003, Biopharm Drug Dispos, 24, 87, 10.1002/bdd.340

Skinner, 2003, Clin Pharmacol Ther, 73, 170, 10.1067/mcp.2003.28

Anttila, 2001, CNS Drug Rev, 7, 249, 10.1111/j.1527-3458.2001.tb00198.x

Wang, 2003, Drug Metab Dispos, 31, 742, 10.1124/dmd.31.6.742

Bottiger, 1996, Br J Clin Pharmacol, 42, 707, 10.1046/j.1365-2125.1996.00471.x

Grace, 1994, Chem Res Toxicol, 7, 286, 10.1021/tx00039a003

Hidestrand, 2001, Drug Metab Dispos, 29, 1480

Gras, 2002, CNS Drug Rev, 8, 217, 10.1111/j.1527-3458.2002.tb00226.x

Pascual, 2003, Drugs Today (Barc), 39, 31

Keam, 2002, Drugs, 62, 387, 10.2165/00003495-200262020-00010

McEnroe, 2005, Clin Pharmacokinet, 44, 237, 10.2165/00003088-200544030-00002

Pichard, 1995, Drug Metab Dispos, 23, 1253

Spaldin, 1994, Br J Clin Pharmacol, 38, 15, 10.1111/j.1365-2125.1994.tb04316.x

Barner, 1998, Ann Pharmacother, 32, 70, 10.1345/aph.17150

Bachus, 1999, Pharmacogenetics, 9, 661, 10.1097/00008571-199912000-00001

Jann, 2002, Clin Pharmacokinet, 41, 719, 10.2165/00003088-200241100-00003

Obach, 1998, Drug Metab Dispos, 26, 764

Davies, 2007, Drug Metab Dispos, 35, 128, 10.1124/dmd.106.012252

Desta, 2004, J Pharmacol Exp Ther, 310, 1062, 10.1124/jpet.104.065607

Beverage, 2007, J Pharm Sci, 96, 2224, 10.1002/jps.20892

Stearns, 2003, J Natl Cancer Inst, 95, 1758, 10.1093/jnci/djg108

Crewe, 2002, Drug Metab Dispos, 30, 869, 10.1124/dmd.30.8.869

Dehal, 1997, Cancer Res, 57, 3402

Narimatsu, 1993, Biochem Biophys Res Commun, 193, 1262, 10.1006/bbrc.1993.1761

Yumibe, 1996, Biochem Pharmacol, 51, 165, 10.1016/0006-2952(95)02169-8

Yumibe, 1995, Int Arch Allergy Immunol, 107, 420, 10.1159/000237063

Nakamura, 1996, Pharmacogenetics, 6, 449, 10.1097/00008571-199610000-00009

Matsumoto, 2001, Br J Clin Pharmacol, 51, 133, 10.1046/j.1365-2125.2001.01292.x

Nakamura, 1998, J Pharmacol Exp Ther, 284, 437

Jones, 1998, Drug Metab Dispos, 26, 875

Imai, 1999, Drug Metab Dispos, 27, 942

Nakajima, 1999, Drug Metab Dispos, 27, 1381

Goto, 2005, Biol Pharm Bull, 28, 328, 10.1248/bpb.28.328

Goto, 2004, Biol Pharm Bull, 27, 684, 10.1248/bpb.27.684

Kishimoto, 1997, Res Commun Mol Pathol Pharmacol, 98, 273

Akutsu, 2007, Drug Metab Dispos, 35, 72, 10.1124/dmd.106.012088

He, 2002, Eur J Clin Pharmacol, 57, 847, 10.1007/s00228-001-0399-0

Yasuda, 2002, Br J Clin Pharmacol, 53, 519, 10.1046/j.1365-2125.2002.01578.x

Postlind, 1998, Drug Metab Dispos, 26, 289

Kudo, 1999, Drug Metab Dispos, 27, 303

Kumar, 1996, J Pharmacol Exp Ther, 277, 423

Erickson, 1999, Drug Metab Dispos, 27, 1488

Voorman, 1998, Drug Metab Dispos, 26, 631

Halliday, 1995, Br J Clin Pharmacol, 40, 369, 10.1111/j.1365-2125.1995.tb04559.x

Gibbs, 2006, Drug Metab Dispos, 34, 1516, 10.1124/dmd.105.008714

Evans, 1989, Clin Pharmacol Ther, 45, 568, 10.1038/clpt.1989.74

Brynne, 1998, Clin Pharmacol Ther, 63, 529, 10.1016/S0009-9236(98)90104-7

Farid, 1985, J Clin Pharmacol, 25, 296, 10.1002/j.1552-4604.1985.tb02842.x

Zoble, 1989, Propafenone Research Group Clin Pharmacol Ther, 45, 535, 10.1038/clpt.1989.69

Gram, 1975, Clin Pharmacol Ther, 17, 555, 10.1002/cpt1975175555

Holliday, 1995, Drugs, 49, 280, 10.2165/00003495-199549020-00010

Breyer-Pfaff, 1992, Clin Pharmacol Ther, 52, 350, 10.1038/clpt.1992.155

Sunwoo, 2004, Clin Pharmacol Ther, 73, PII

Ebner, 1993, Br J Clin Pharmacol, 35, 426, 10.1111/j.1365-2125.1993.tb04161.x

Wang, 2009, Drug Metab Dispos, 37, 977, 10.1124/dmd.108.026047

Kagimoto, 1990, J Biol Chem, 265, 17209, 10.1016/S0021-9258(17)44890-3

Evert, 1997, Naunyn Schmiedebergs Arch Pharmacol, 355, 309, 10.1007/PL00004948

Gaedigk, 1991, Am J Hum Genet, 48, 943

Skoda, 1988, Proc Natl Acad Sci U S A, 85, 5240, 10.1073/pnas.85.14.5240

Marez, 1997, Pharmacogenetics, 7, 193, 10.1097/00008571-199706000-00004

Dahl, 1992, Clin Pharmacol Ther, 51, 12, 10.1038/clpt.1992.2

Masimirembwa, 1996, Eur J Clin Pharmacol, 51, 117, 10.1007/s002280050170

Simooya, 1993, Pharmacogenetics, 3, 205, 10.1097/00008571-199308000-00005

Gaedigk, 2006, Drug Metab Dispos, 34, 563, 10.1124/dmd.105.008292

Evert, 1994, Naunyn Schmiedebergs Arch Pharmacol, 350, 434, 10.1007/BF00178963

Marez, 1995, Pharmacogenetics, 5, 305, 10.1097/00008571-199510000-00006

Marez-Allorge, 1999, Pharmacogenetics, 9, 393, 10.1097/00008571-199906000-00015

Li, 2006, Drug Metab Dispos, 34, 1411, 10.1124/dmd.106.009548

Klein, 2007, Drug Metab Dispos, 35, 1247, 10.1124/dmd.107.015149

Marez, 1996, Hum Genet, 97, 668, 10.1007/BF02281880

Wang, 1999, Drug Metab Dispos, 27, 385

Kubota, 2000, Br J Clin Pharmacol, 50, 31, 10.1046/j.1365-2125.2000.00209.x

Daly, 1996, Pharmacogenetics, 6, 193, 10.1097/00008571-199606000-00001

Sakuyama, 2008, Drug Metab Dispos, 36, 2460, 10.1124/dmd.108.023242

Ji, 2002, Clin Chem, 48, 983, 10.1093/clinchem/48.7.983

Yokoi, 1996, Pharmacogenetics, 6, 395, 10.1097/00008571-199610000-00003

Steen, 1995, Hum Mol Genet, 4, 2251, 10.1093/hmg/4.12.2251

Idle, 2000, Lancet, 355, 319, 10.1016/S0140-6736(05)72317-5

Panserat, 1995, Br J Clin Pharmacol, 40, 361, 10.1111/j.1365-2125.1995.tb04558.x

Daly, 1996, Pharmacogenetics, 6, 319, 10.1097/00008571-199608000-00005

Johansson, 1994, Mol Pharmacol, 46, 452

Ishiguro, 2004, Clin Chim Acta, 347, 217, 10.1016/j.cccn.2004.04.020

Leathart, 1998, Pharmacogenetics, 8, 529, 10.1097/00008571-199812000-00010

Yokota, 1993, Pharmacogenetics, 3, 256, 10.1097/00008571-199310000-00005

Huang, 1999, Clin Pharmacol Ther, 65, 402, 10.1016/S0009-9236(99)70134-7

Yue, 1998, Clin Pharmacol Ther, 64, 384, 10.1016/S0009-9236(98)90069-8

Yamazaki, 1993, J Biochem, 114, 652, 10.1093/oxfordjournals.jbchem.a124232

Shen, 2007, Drug Metab Dispos, 35, 1292, 10.1124/dmd.107.015354

Garcia-Barcelo, 2000, Clin Chem, 46, 1411, 10.1093/clinchem/46.9.1411

Mitsunaga, 2002, Mutat Res, 505, 83, 10.1016/S0027-5107(02)00122-7

Masimirembwa, 1996, Br J Clin Pharmacol, 42, 713, 10.1046/j.1365-2125.1996.00489.x

Wennerholm, 1999, Pharmacogenetics, 9, 707, 10.1097/00008571-199912000-00005

Griese, 1999, Pharmacogenetics, 9, 715, 10.1097/00008571-199912000-00006

Oscarson, 1997, Mol Pharmacol, 52, 1034, 10.1124/mol.52.6.1034

Bogni, 2005, Toxicol In Vitro, 19, 621, 10.1016/j.tiv.2005.04.001

Cai, 2006, Pharmacogenomics J, 6, 343, 10.1038/sj.tpj.6500378

Fukuda, 2000, Arch Biochem Biophys, 380, 303, 10.1006/abbi.2000.1936

Chida, 2002, Pharmacogenetics, 12, 659, 10.1097/00008571-200211000-00011

Raimundo, 2000, Pharmacogenetics, 10, 577, 10.1097/00008571-200010000-00001

Raimundo, 2004, Clin Pharmacol Ther, 76, 128, 10.1016/j.clpt.2004.04.009

Toscano, 2006, Pharmacogenet Genomics, 16, 755, 10.1097/01.fpc.0000230112.96086.e0

Soyama, 2004, Drug Metab Pharmacokinet, 19, 313, 10.2133/dmpk.19.313

Rowland, 2006, J Biol Chem, 281, 7614, 10.1074/jbc.M511232200

Soyama, 2006, Drug Metab Pharmacokinet, 21, 208, 10.2133/dmpk.21.208

Gaedigk, 2005, Pharmacogenomics J, 5, 173, 10.1038/sj.tpj.6500305

Johansson, 1993, Proc Natl Acad Sci U S A, 90, 11825, 10.1073/pnas.90.24.11825

Flanagan, 2004, Biochem J, 380, 353, 10.1042/bj20040062

Keizers, 2004, Biochem Pharmacol, 68, 2263, 10.1016/j.bcp.2004.08.013

McLaughlin, 2005, J Biol Chem, 280, 38617, 10.1074/jbc.M505974200

Solus, 2004, Pharmacogenomics, 5, 895, 10.1517/14622416.5.7.895

Panserat, 1994, Hum Genet, 94, 401, 10.1007/BF00201601

Gaedigk, 2007, Clin Pharmacol Ther, 81, 242, 10.1038/sj.clpt.6100033

Bertilsson, 1993, Lancet, 341, 63, 10.1016/0140-6736(93)92546-6

Aklillu, 2002, Pharmacogenetics, 12, 375, 10.1097/00008571-200207000-00005

Nishida, 2000, Pharmacogenetics, 10, 567, 10.1097/00008571-200008000-00010

Bathum, 1998, Pharmacogenetics, 8, 119, 10.1097/00008571-199804000-00004

Bathum, 1999, Br J Clin Pharmacol, 48, 395, 10.1046/j.1365-2125.1999.00019.x

Sistonen, 2009, Pharmacogenet Genomics, 19, 170, 10.1097/FPC.0b013e32831ebb30

Sistonen, 2007, Pharmacogenet Genomics, 17, 93, 10.1097/01.fpc.0000239974.69464.f2

Kirchheiner, 2008, J Clin Psychopharmacol, 28, 78, 10.1097/JCP.0b013e318160f827

Stamer, 2007, Clin Pharmacol Ther, 82, 41, 10.1038/sj.clpt.6100152

Shams, 2006, J Clin Pharm Ther, 31, 493, 10.1111/j.1365-2710.2006.00763.x

Kirchheiner, 2007, Pharmacogenomics J, 7, 257, 10.1038/sj.tpj.6500406

Kirchheiner, 2004, J Clin Psychopharmacol, 24, 647, 10.1097/01.jcp.0000145341.30547.f0

Kirchheiner, 2004, Clin Pharmacol Ther, 76, 302, 10.1016/j.clpt.2004.07.002

Goryachkina, 2008, Eur J Clin Pharmacol, 64, 1163, 10.1007/s00228-008-0525-3

Dalen, 1997, Ther Drug Monit, 19, 543, 10.1097/00007691-199710000-00011

Horai, 1989, Clin Pharmacol Ther, 46, 198, 10.1038/clpt.1989.126

Sohn, 1991, Br J Clin Pharmacol, 32, 504, 10.1111/j.1365-2125.1991.tb03939.x

Horai, 1990, Br J Clin Pharmacol, 29, 111, 10.1111/j.1365-2125.1990.tb03609.x

Lamba, 1998, Eur J Clin Pharmacol, 54, 787, 10.1007/s002280050552

Gaedigk, 2002, Clin Pharmacol Ther, 72, 76, 10.1067/mcp.2002.125783

Evans, 1993, J Clin Invest, 91, 2150, 10.1172/JCI116441

Relling, 1991, Clin Pharmacol Ther, 50, 308, 10.1038/clpt.1991.141

Jorge, 1999, Pharmacogenetics, 9, 217

Griese, 1998, Pharmacogenetics, 8, 15, 10.1097/00008571-199802000-00003

London, 1997, Carcinogenesis, 18, 1203, 10.1093/carcin/18.6.1203

Scordo, 1999, Psychopharmacology (Berl), 147, 300, 10.1007/s002130051171

Agundez, 1995, Clin Pharmacol Ther, 57, 265, 10.1016/0009-9236(95)90151-5

Bernal, 1999, Pharmacogenetics, 9, 657, 10.1097/00008571-199910000-00013

Aynacioglu, 1999, Clin Pharmacol Ther, 66, 185, 10.1016/S0009-9236(99)90056-5

McLellan, 1997, Pharmacogenetics, 7, 187, 10.1097/00008571-199706000-00003

Lin, 1983, Am J Psychiatry, 140, 490, 10.1176/ajp.140.9.1268-a

Mihara, 1997, Psychopharmacology (Berl), 133, 95, 10.1007/s002130050376

Horowitz, 1995, Aust N Z J Med, 25, 111, 10.1111/j.1445-5994.1995.tb02820.x

Ashrafian, 2007, Cardiovasc Drug Rev, 25, 76, 10.1111/j.1527-3466.2007.00006.x

Cole, 1990, Circulation, 81, 1260, 10.1161/01.CIR.81.4.1260

Sorensen, 2003, Br J Clin Pharmacol, 55, 635, 10.1046/j.1365-2125.2003.01805.x

Sallustio, 2002, Br J Clin Pharmacol, 54, 107, 10.1046/j.1365-2125.2002.01618.x

Barclay, 2003, Pharmacogenetics, 13, 627, 10.1097/00008571-200310000-00006

Cooper, 1984, J Med Genet, 21, 27, 10.1136/jmg.21.1.27

Cooper, 1987, Eur J Clin Pharmacol, 32, 569, 10.1007/BF02455990

Morgan, 1984, Gut, 25, 1057, 10.1136/gut.25.10.1057

Shah, 1982, Br Med J (Clin Res Ed), 284, 295, 10.1136/bmj.284.6312.295

Follath, 1992, J Cardiovasc Pharmacol, 20, S41, 10.1097/00005344-199220002-00008

Niwa, 2000, Drug Metab Dispos, 28, 1128

Abolfathi, 1993, J Pharmacol Exp Ther, 266, 1196

Broly, 1990, Biochem Pharmacol, 39, 1045, 10.1016/0006-2952(90)90283-Q

Botsch, 1993, Mol Pharmacol, 43, 120

Kroemer, 1991, Mol Pharmacol, 40, 135

Kroemer, 1989, Clin Pharmacol Ther, 45, 28, 10.1038/clpt.1989.5

Funck-Brentano, 1992, J Pharmacol Exp Ther, 263, 780

Haefeli, 1990, J Cardiovasc Pharmacol, 15, 776, 10.1097/00005344-199005000-00013

Mehvar, 2002, Clin Pharmacokinet, 41, 533, 10.2165/00003088-200241080-00001

Turgeon, 1989, Clin Pharmacol Ther, 45, 692, 10.1038/clpt.1989.91

Carey, 1984, J Clin Invest, 73, 539, 10.1172/JCI111241

Barbey, 1988, Circulation, 77, 380, 10.1161/01.CIR.77.2.380

Roden, 1986, Am J Cardiol, 58, 4, 10.1016/0002-9149(86)90097-4

McAllister, 1986, Xenobiotica, 16, 483, 10.3109/00498258609050253

Woosley, 1986, Clin Pharmacol Ther, 39, 282, 10.1038/clpt.1986.40

Wang, 1984, J Pharmacol Exp Ther, 228, 605

Sauer, 2003, Drug Metab Dispos, 31, 98, 10.1124/dmd.31.1.98

Zhou, 1995, Clin Pharmacol Ther, 57, 518, 10.1016/0009-9236(95)90036-5

Giessmann, 2004, Clin Pharmacol Ther, 75, 213, 10.1016/j.clpt.2003.10.004

Yasuda, 1995, Clin Pharmacol Ther, 58, 210, 10.1016/0009-9236(95)90199-X

Nielsen, 1992, Eur J Clin Pharmacol, 43, 405, 10.1007/BF02220617

Sindrup, 1990, Br J Clin Pharmacol, 30, 683, 10.1111/j.1365-2125.1990.tb03836.x

Lotsch, 2004, Clin Pharmacokinet, 43, 983, 10.2165/00003088-200443140-00003

Eckhardt, 1998, Pain, 76, 27, 10.1016/S0304-3959(98)00021-9

Caraco, 1996, J Pharmacol Exp Ther, 278, 1165

Spina, 1987, Clin Pharmacol Ther, 41, 314, 10.1038/clpt.1987.33

Spina, 1997, Eur J Clin Pharmacol, 51, 395, 10.1007/s002280050220

Brosen, 1986, Eur J Clin Pharmacol, 30, 679, 10.1007/BF00608215

Brosen, 1993, Eur J Clin Pharmacol, 44, 349, 10.1007/BF00316471

Fromm, 1995, Clin Pharmacol Ther, 58, 374, 10.1016/0009-9236(95)90049-7

Kirchheiner, 2002, Pharmacogenetics, 12, 571, 10.1097/00008571-200210000-00010

Gross, 1991, Eur J Clin Pharmacol, 40, 155, 10.1007/BF00280070

Mikus, 1989, Clin Pharmacol Ther, 45, 562, 10.1038/clpt.1989.73

Fjordside, 1999, Pharmacogenetics, 9, 55, 10.1097/00008571-199902000-00008

Hamelin, 1996, Clin Pharmacol Ther, 60, 512, 10.1016/S0009-9236(96)90147-2

Scordo, 2005, Basic Clin Pharmacol Toxicol, 97, 296, 10.1111/j.1742-7843.2005.pto_194.x

Brosen, 1986, Clin Pharmacol Ther, 40, 543, 10.1038/clpt.1986.221

Steiner, 1987, Clin Pharmacol Ther, 42, 278, 10.1038/clpt.1987.147

Firkusny, 1994, Br J Clin Pharmacol, 37, 383, 10.1111/j.1365-2125.1994.tb04293.x

Lennard, 1983, Clin Pharmacol Ther, 34, 732, 10.1038/clpt.1983.242

Hamelin, 2000, Clin Pharmacol Ther, 67, 466, 10.1067/mcp.2000.106464

Lennard, 1982, Br J Clin Pharmacol, 14, 301, 10.1111/j.1365-2125.1982.tb01982.x

Broly, 1991, Br J Clin Pharmacol, 32, 459, 10.1111/j.1365-2125.1991.tb03931.x

Dahl, 1994, Clin Pharmacol Ther, 56, 176, 10.1038/clpt.1994.121

Mihara, 1997, J Clin Psychopharmacol, 17, 467, 10.1097/00004714-199712000-00005

Dalen, 1998, Clin Pharmacol Ther, 63, 444, 10.1016/S0009-9236(98)90040-6

Morita, 2000, J Clin Psychopharmacol, 20, 141, 10.1097/00004714-200004000-00005

Sindrup, 1992, Clin Pharmacol Ther, 51, 278, 10.1038/clpt.1992.23

Ozdemir, 1997, Clin Pharmacol Ther, 62, 334, 10.1016/S0009-9236(97)90037-0

Pollock, 1995, Psychopharmacol Bull, 31, 327

Dahl-Puustinen, 1989, Clin Pharmacol Ther, 46, 78, 10.1038/clpt.1989.109

Linnet, 1996, Clin Pharmacol Ther, 60, 41, 10.1016/S0009-9236(96)90165-4

Ozdemir, 2007, Pharmacogenet Genomics, 17, 339, 10.1097/FPC.0b013e32801a3c10

Labbe, 2000, Clin Pharmacol Ther, 68, 44, 10.1067/mcp.2000.108023

Cai, 1999, Br J Clin Pharmacol, 47, 553, 10.1046/j.1365-2125.1999.00932.x

Siddoway, 1987, Circulation, 75, 785, 10.1161/01.CIR.75.4.785

Dilger, 1999, Pharmacogenetics, 9, 551, 10.1097/00008571-199910000-00002

Lee, 1990, N Engl J Med, 322, 1764, 10.1056/NEJM199006213222502

Chen, 2003, Acta Pharmacol Sin, 24, 1277

Bondolfi, 2002, Pharmacopsychiatry, 35, 50, 10.1055/s-2002-25026

Olesen, 1998, Ther Drug Monit, 20, 380, 10.1097/00007691-199808000-00004

Nyberg, 1995, Psychopharmacology (Berl), 119, 345, 10.1007/BF02246302

Roh, 2001, Eur J Clin Pharmacol, 57, 671, 10.1007/s002280100372

van der Weide, 2005, Ther Drug Monit, 27, 478, 10.1097/01.ftd.0000162868.84596.c3

Leon, 2007, Pharmacopsychiatry, 40, 93, 10.1055/s-2007-973836

Jin, 2005, J Natl Cancer Inst, 97, 30, 10.1093/jnci/dji005

Schroth, 2007, J Clin Oncol, 25, 5187, 10.1200/JCO.2007.12.2705

Goetz, 2007, Breast Cancer Res Treat, 101, 113, 10.1007/s10549-006-9428-0

Borges, 2006, Clin Pharmacol Ther, 80, 61, 10.1016/j.clpt.2006.03.013

Goetz, 2005, J Clin Oncol, 23, 9312, 10.1200/JCO.2005.03.3266

Lim, 2007, J Clin Oncol, 25, 3837, 10.1200/JCO.2007.11.4850

von Bahr, 1991, Clin Pharmacol Ther, 49, 234, 10.1038/clpt.1991.22

Lewis, 1985, Br J Clin Pharmacol, 19, 329, 10.1111/j.1365-2125.1985.tb02651.x

Poulsen, 1996, Clin Pharmacol Ther, 60, 636, 10.1016/S0009-9236(96)90211-8

Fliegert, 2005, Eur J Clin Pharmacol, 61, 257, 10.1007/s00228-005-0920-y

Kim, 2003, Eur J Clin Pharmacol, 59, 111, 10.1007/s00228-003-0595-1

Kaiser, 2002, J Clin Oncol, 20, 2805, 10.1200/JCO.2002.09.064

Lessard, 1999, Pharmacogenetics, 9, 435, 10.1097/00008571-199912000-00003

Fukuda, 2000, Eur J Clin Pharmacol, 56, 175, 10.1007/s002280050737

Lindh, 2003, Eur J Clin Pharmacol, 59, 401, 10.1007/s00228-003-0627-x

Whyte, 2006, Int J Geriatr Psychiatry, 21, 542, 10.1002/gps.1522

Linnet, 1996, Ther Drug Monit, 18, 629, 10.1097/00007691-199612000-00001

Roden, 1988, Clin Pharmacokinet, 14, 141, 10.2165/00003088-198814030-00002

Anderson, 1981, N Engl J Med, 305, 473, 10.1056/NEJM198108273050901

McQuinn, 1984, Drug Metab Dispos, 12, 414

Gross, 1989, Br J Clin Pharmacol, 28, 555, 10.1111/j.1365-2125.1989.tb03542.x

Doki, 2006, Eur J Clin Pharmacol, 62, 919, 10.1007/s00228-006-0188-x

Martinez-Selles, 2005, Rev Esp Cardiol, 58, 745, 10.1157/13076423

Funck-Brentano, 1994, Clin Pharmacol Ther, 55, 256, 10.1038/clpt.1994.26

Tenneze, 2002, Clin Pharmacol Ther, 72, 112, 10.1067/mcp.2002.125946

Birgersdotter, 1992, Br J Clin Pharmacol, 33, 275, 10.1111/j.1365-2125.1992.tb04035.x

Lim, 2008, Br J Clin Pharmacol, 66, 660, 10.1111/j.1365-2125.2008.03267.x

Monk, 1990, Drugs, 40, 374, 10.2165/00003495-199040030-00005

Vandamme, 1993, J Cardiovasc Pharmacol, 21, 77, 10.1097/00005344-199301000-00011

Beckett, 1977, J Pharm Pharmacol, 29, 281, 10.1111/j.2042-7158.1977.tb11312.x

Turgeon, 1991, J Pharmacol Exp Ther, 259, 789

Broly, 1991, Life Sci, 48, PL123, 10.1016/0024-3205(91)90618-L

Turgeon, 1992, Drug Metab Dispos, 20, 762

Klein, 1985, Clin Pharmacol Ther, 37, 669, 10.1038/clpt.1985.109

Brockmeyer, 1989, Eur J Clin Pharmacol, 36, 375, 10.1007/BF00558298

Yonezawa, 2002, J Clin Pharmacol, 42, 342, 10.1177/00912700222011265

Ueno, 1996, Eur J Clin Pharmacol, 50, 129, 10.1007/s002280050080

Kusumoto, 1998, Ann Pharmacother, 32, 182, 10.1345/aph.17177

Bryson, 1993, Drugs, 45, 85, 10.2165/00003495-199345010-00008

Kroemer, 1989, Circulation, 79, 1068, 10.1161/01.CIR.79.5.1068

Hege, 1984, Eur J Drug Metab Pharmacokinet, 9, 41, 10.1007/BF03189604

Zhou, 2003, Pharmazie, 58, 651

Funck-Brentano, 1989, J Pharmacol Exp Ther, 249, 134

Capucci, 1990, Cardiovasc Drugs Ther, 4, 281, 10.1007/BF01857646

Anzenbacherova, 2000, Int J Clin Pharmacol Ther, 38, 426, 10.5414/CPP38426

Jazwinska-Tarnawska, 2001, Int J Clin Pharmacol Ther, 39, 288, 10.5414/CPP39288

Morike, 1994, Clin Pharmacol Ther, 55, 28, 10.1038/clpt.1994.6

Morike, 1995, J Intern Med, 238, 469, 10.1111/j.1365-2796.1995.tb01225.x

Ujhelyi, 1993, Clin Pharmacol Ther, 53, 38, 10.1038/clpt.1993.7

Kowey, 1989, J Clin Pharmacol, 29, 512, 10.1002/j.1552-4604.1989.tb03373.x

Wagner, 1987, Br J Clin Pharmacol, 24, 213, 10.1111/j.1365-2125.1987.tb03164.x

Katz, 1991, J Clin Psychiatry, 52, 432

Cai, 1999, Clin Pharmacol Ther, 66, 516, 10.1016/S0009-9236(99)70015-9

Roy, 2008, Circulation, 117, 1518, 10.1161/CIRCULATIONAHA.107.723866

Naccarelli, 2008, Drugs Today (Barc), 44, 325, 10.1358/dot.2008.44.5.1216597

Mao, 2009, J Clin Pharmacol, 49, 17, 10.1177/0091270008325148

Mehvar, 2001, J Pharm Pharm Sci, 4, 185

Oldham, 1997, Drug Metab Dispos, 25, 970

Narimatsu, 2002, J Pharmacol Exp Ther, 303, 172, 10.1124/jpet.102.036533

Mautz, 1995, Drug Metab Dispos, 23, 513

McGourty, 1985, Br J Clin Pharmacol, 20, 555, 10.1111/j.1365-2125.1985.tb05112.x

Belpaire, 1998, Eur J Clin Pharmacol, 54, 261, 10.1007/s002280050456

Tassaneeyakul, 1993, J Pharmacol Exp Ther, 265, 401

Masubuchi, 1994, Drug Metab Dispos, 22, 909

Johnson, 2000, J Pharmacol Exp Ther, 294, 1099

Volotinen, 2007, Drug Metab Dispos, 35, 1135, 10.1124/dmd.106.012906

McTavish, 1993, Drugs, 45, 232, 10.2165/00003495-199345020-00006

Keating, 2003, Drugs, 63, 1697, 10.2165/00003495-200363160-00006

Neugebauer, 1990, Eur J Clin Pharmacol, 38, S108, 10.1007/BF01409476

Honda, 2005, Biol Pharm Bull, 28, 1476, 10.1248/bpb.28.1476

Prakash, 2000, Drugs, 60, 647, 10.2165/00003495-200060030-00011

Dayer, 1985, Eur J Clin Pharmacol, 28, 149, 10.1007/BF00609683

Borg, 1975, Acta Pharmacol Toxicol (Copenh), 36, 125, 10.1111/j.1600-0773.1975.tb03329.x

Otton, 1988, J Pharmacol Exp Ther, 247, 242

Johnson, 1996, Drug Metab Dispos, 24, 350

Hoffmann, 1980, Clin Pharmacokinet, 5, 181, 10.2165/00003088-198005020-00005

Hemeryck, 2000, Clin Pharmacol Ther, 67, 283, 10.1067/mcp.2000.104788

Hemeryck, 2001, Drug Metab Dispos, 29, 656

Kim, 1993, Drug Metab Dispos, 21, 309

Seeringer, 2008, Eur J Clin Pharmacol, 64, 883, 10.1007/s00228-008-0504-8

Wuttke, 2002, Clin Pharmacol Ther, 72, 429, 10.1067/mcp.2002.127111

Zineh, 2004, Clin Pharmacol Ther, 76, 536, 10.1016/j.clpt.2004.08.020

Fux, 2005, Clin Pharmacol Ther, 78, 378, 10.1016/j.clpt.2005.07.004

Bijl, 2009, Clin Pharmacol Ther, 85, 45, 10.1038/clpt.2008.172

Talaat, 1988, Drug Metab Dispos, 16, 212

Ward, 1989, Clin Pharmacol Ther, 45, 72, 10.1038/clpt.1989.11

Lennard, 1984, Br J Clin Pharmacol, 17, 679, 10.1111/j.1365-2125.1984.tb02403.x

Lennard, 1986, Xenobiotica, 16, 435, 10.3109/00498258609050250

Raghuram, 1984, Clin Pharmacol Ther, 36, 51, 10.1038/clpt.1984.138

Lennard, 1984, Br J Clin Pharmacol, 17, 106, 10.1111/j.1365-2125.1984.tb02441.x

Sowinski, 1997, Pharmacotherapy, 17, 1305, 10.1002/j.1875-9114.1997.tb03097.x

Shaheen, 1989, Clin Pharmacol Ther, 45, 439, 10.1038/clpt.1989.52

Lai, 1995, Clin Pharmacol Ther, 58, 264, 10.1016/0009-9236(95)90242-2

Zhou, 1990, Clin Pharmacol Ther, 47, 686, 10.1038/clpt.1990.94

Frishman, 1994, J Clin Pharmacol, 34, 795, 10.1002/j.1552-4604.1994.tb02042.x

Heel, 1979, Drugs, 17, 38, 10.2165/00003495-197917010-00002

Nieminen, 2007, Scand J Clin Lab Invest, 67, 237, 10.1080/00365510601034736

Lama, 2002, Am J Ophthalmol, 134, 749, 10.1016/S0002-9394(02)01699-9

Vander Zanden, 2001, Ann Pharmacother, 35, 1633, 10.1345/aph.18464

Kaila, 1991, Clin Pharmacol Ther, 49, 53, 10.1038/clpt.1991.10

Huupponen, 1991, J Ocul Pharmacol, 7, 183, 10.1089/jop.1991.7.183

Nieminen, 2005, Eur J Clin Pharmacol, 61, 811, 10.1007/s00228-005-0052-4

Edeki, 1995, JAMA, 274, 1611, 10.1001/jama.1995.03530200047035