Polylactic Acid Based Nanocomposites: Promising Safe and Biodegradable Materials in Biomedical Field

International Journal of Polymer Science - Tập 2016 - Trang 1-11 - 2016
Lili Sha1,2, Zhaofeng Chen1,2, Zhou Chen1,3, Aili Zhang3, Zhaogang Yang3
1College of Material Science and Technology, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China
2Suqian NUAA Institute of New Materials and New Equipment Manufacturing Co., Ltd., Suqian 223800, China
3Nanoscale Science and Engineering Center, The Ohio State University, Columbus, OH 43210, USA

Tóm tắt

Polylactic acid (PLA) is widely used in biological areas due to its excellent compatibility, bioabsorbability, and degradation behavior in human bodies. Pure polylactic acid has difficulty in meeting all the requirements that specific field may demand. Therefore, PLA based nanocomposites are extensively investigated over the past few decades. PLA based nanocomposites include PLA based copolymers in nanometer size and nanocomposites with PLA or PLA copolymers as matrix and nanofillers as annexing agent. The small scale effect and surface effect of nanomaterials help improve the properties of PLA and make PLA based nanocomposites more popular compared with pure PLA materials. This review mainly introduces different kinds of PLA based nanocomposites in recent researches that have great potential to be used in biomedical fields including bone substitute and repair, tissue engineering, and drug delivery system.

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Tài liệu tham khảo

10.1038/nature02388

10.1164/rccm.201511-2129le

10.1016/j.biotechadv.2016.04.002

10.1039/c6bm00070c

10.2174/1381612821666151027152121

2015, Current Pharmaceutical Biotechnology, 15, 829

10.1039/c4nr01510j

10.1016/j.actbio.2014.08.003

10.1021/mp300504z

10.1016/j.jconrel.2016.03.032

10.1021/la302779q

10.3390/ma8084912

10.1155/2013/710502

10.1007/s11095-014-1366-7

10.1166/sam.2016.2719

10.1039/c3cp51556g

10.1039/c4ra09979f

10.1126/science.8134835

10.1016/j.biomaterials.2006.01.039

10.1016/j.clay.2013.12.005

10.1016/j.carbon.2016.04.052

10.1021/ie503434q

2013, Degradable and resorbable biomaterials, 179

10.1016/s0032-3861(01)00086-6

10.1016/s1359-6446(02)02255-9

2014, Journal of Applied Polymer Science, 131, 205

10.1016/j.biortech.2010.05.092

10.1016/s0032-3861(96)00455-7

10.1016/0032-3861(96)82913-2

10.1002/(sici)1097-4628(19971121)66:8<1495::aid-app10>3.0.co;2-3

10.1016/j.polymer.2014.06.059

10.1016/j.polymer.2013.10.035

10.1002/pen.23550

10.1002/app.36770

10.1007/s10570-013-0007-3

10.1016/j.egypro.2014.07.151

10.1016/j.clay.2015.01.004

10.1016/j.cej.2014.11.066

10.1002/pi.4290

10.1016/j.clay.2015.08.017

10.1186/1741-7015-9-66

10.1016/j.soc.2011.11.001

10.1097/moo.0b013e328347f895

10.1177/0194599811435633

10.1007/s10561-015-9510-0

10.1016/0142-9612(95)00327-4

10.1016/s0141-8130(99)00043-4

10.1016/0278-2391(91)90065-t

2010

10.1089/ten.teb.2012.0443

10.1016/j.ijpharm.2014.06.033

10.1002/jbm.b.30878

10.2174/1874325001105010063

10.1016/j.actbio.2008.11.030

1987, The Orthopedic Clinics of North America, 18, 323, 10.1016/S0030-5898(20)30395-3

10.1016/0142-9612(86)90071-2

10.1557/JMR.1998.0015

10.1016/j.biomaterials.2005.09.003

10.1007/bf00122979

2000, Journal of Biomedical Materials Research, 50, 410, 10.1002/(SICI)1097-4636(20000605)50:3<410::AID-JBM16>3.0.CO;2-Y

1999, Journal of Biomedical Materials Research, 47, 412, 10.1002/(SICI)1097-4636(19991205)47:3<412::AID-JBM17>3.0.CO;2-B

10.1002/jbm.b.10027

10.1038/pj.2014.121

10.1007/s00441-013-1770-z

10.1016/j.compscitech.2005.04.051

2003, Journal of Biomedical Materials Research—Part A, 66, 335

10.1002/jbm.b.33364

2014, The Journal of the Western Society of Periodontology/Periodontal Abstracts, 62, 35

10.3390/jfb6030667

10.1007/s13233-015-3138-6

10.1016/j.biomaterials.2004.06.051

10.1186/s12951-015-0081-9

10.1016/0032-3861(94)90953-9

10.1002/jbm.a.31392

10.1002/(sici)1097-4636(199704)35:1<107::aid-jbm11>3.0.co;2-g

10.1016/0142-9612(96)87284-x

10.1007/s11814-009-0309-1

10.1088/1748-6041/10/4/045018

10.1002/jbm.b.30396

10.1088/0960-1317/18/5/055027

10.3390/polym7101500

10.1016/j.msec.2015.08.026

10.1002/jbm.a.35400

10.2174/1568009616666151130213910

2015, Biomaterials Science, 4, 365

10.2174/1381612821666150901104821

10.2147/IJN.S32817

10.2174/1389201015666140617092552

10.1016/j.msec.2015.11.067

10.1007/s00280-006-0287-5

10.2147/ijn.s54050

10.1016/j.colsurfb.2009.09.001

10.1016/0378-5173(89)90281-0

10.1016/j.nano.2005.12.003

10.1016/0168-3659(95)00164-6

10.1016/S0168-3659(99)00244-8

10.1016/S0378-5173(99)00153-2

10.1016/j.ijbiomac.2006.07.001

10.1016/j.jconrel.2005.06.010

10.1016/S0939-6411(01)00169-2

10.1016/s0168-3659(98)00116-3

10.1016/j.biomaterials.2005.12.021

10.1080/02652040400026442

10.1016/s0736-0266(01)00174-7

10.1039/c5cc03692e

10.1016/s0169-409x(02)00226-0

10.1016/s0169-409x(01)00244-7

10.1016/j.biomaterials.2006.10.034

10.1208/s12249-012-9781-8

10.1016/s0168-3659(00)00295-9

10.1088/1748-6041/1/1/005

10.2147/IJN.S17296

10.1007/978-81-322-2491-4_10

10.1016/j.clay.2015.06.017

10.1016/j.jconrel.2007.09.013

10.3109/02652049809006876