Poliovirus RNA Replication Requires Genome Circularization through a Protein–Protein Bridge

Molecular Cell - Tập 7 - Trang 581-591 - 2001
Jens Herold1, Raul Andino1
1Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143 USA

Tài liệu tham khảo

Andino, 1990, A functional ribonucleoprotein complex forms around the 5′ end of poliovirus RNA, Cell, 63, 369, 10.1016/0092-8674(90)90170-J Andino, 1990, Substitutions in the protease (3Cpro) gene of poliovirus can suppress a mutation in the 5′ noncoding region, J. Virol., 64, 607, 10.1128/JVI.64.2.607-612.1990 Andino, 1993, Poliovirus RNA synthesis utilizes an RNP complex formed around the 5′- end of viral RNA, EMBO J., 12, 3587, 10.1002/j.1460-2075.1993.tb06032.x Barton, 1995, Complete replication of poliovirus in vitro, J. Virol., 69, 5516, 10.1128/JVI.69.9.5516-5527.1995 Barton, 1996, Assays for poliovirus polymerase, 3D(Pol), and authentic RNA replication in HeLa S10 extracts, Methods Enzymol., 275, 35, 10.1016/S0076-6879(96)75005-X Barton, 1999, Translating ribosomes inhibit poliovirus negative-strand RNA synthesis, J. Virol., 73, 10104, 10.1128/JVI.73.12.10104-10112.1999 Buck, 1996, Comparison of the replication of positive-stranded RNA viruses of plants and animals, Adv. Virus Res., 47, 159, 10.1016/S0065-3527(08)60736-8 Deo, 1999, Recognition of polyadenylate RNA by the poly(A)-binding protein, Cell, 98, 835, 10.1016/S0092-8674(00)81517-2 Diez, 2000, Identification and characterization of a host protein required for efficient template selection in viral RNA replication, Proc. Natl. Acad. Sci. USA, 97, 3913, 10.1073/pnas.080072997 Flanegan, 1977, Covalent linkage of a protein to a defined nucleotide sequence at the 5′-terminus of virion and replicative intermediate RNAs of poliovirus, Proc. Natl. Acad. Sci. USA, 74, 961, 10.1073/pnas.74.3.961 Gamarnik, 1996, Replication of poliovirus in Xenopus oocytes requires two human factors, EMBO J., 15, 5988, 10.1002/j.1460-2075.1996.tb00985.x Gamarnik, 1997, Two functional complexes formed by KH domain containing proteins with the 5′ noncoding region of poliovirus RNA, RNA, 3, 882 Gamarnik, 1998, Switch from translation to RNA replication in a positive-stranded RNA virus, Genes Dev., 12, 2293, 10.1101/gad.12.15.2293 Gingras, 1999, eIF4 initiation factors, Annu. Rev. Biochem., 68, 913, 10.1146/annurev.biochem.68.1.913 Gorlach, 1994, The mRNA poly(A)-binding protein, Exp. Cell Res., 211, 400, 10.1006/excr.1994.1104 Grundhoff, 1999, Characterization of DP103, a novel DEAD box protein that binds to the Epstein-Barr virus nuclear proteins EBNA2 and EBNA3C, J. Biol. Chem., 274, 19136, 10.1074/jbc.274.27.19136 Hahn, 1987, Conserved elements in the 3′ untranslated region of flavivirus RNAs and potential cyclization sequences, J. Mol. Biol., 198, 33, 10.1016/0022-2836(87)90455-4 Herold, 2000, Poliovirus requires a precise 5′ end for efficient positive-strand RNA synthesis, J. Virol., 74, 6394, 10.1128/JVI.74.14.6394-6400.2000 Herold, 1999, A human RNA viral cysteine proteinase that depends upon a unique Zn2+- binding finger connecting the two domains of a papain-like fold, J. Biol. Chem., 274, 14918, 10.1074/jbc.274.21.14918 Joachims, 1999, Cleavage of poly(A)-binding protein by enterovirus proteases concurrent with inhibition of translation in vitro, J. Virol., 73, 718, 10.1128/JVI.73.1.718-727.1999 Kerekatte, 1999, Cleavage of Poly(A)-binding protein by coxsackievirus 2A protease in vitro and in vivo, J. Virol., 73, 709, 10.1128/JVI.73.1.709-717.1999 Kiledjian, 1995, Identification of two KH domain proteins in the alpha-globin mRNP stability complex, EMBO J., 14, 4357, 10.1002/j.1460-2075.1995.tb00110.x Klovins, 1999, A long-range pseudoknot in Qbeta RNA is essential for replication, J. Mol. Biol., 294, 875, 10.1006/jmbi.1999.3274 Klovins, 1998, A long-range interaction in Qbeta RNA that bridges the thousand nucleotides between the M-site and the 3′ end is required for replication, RNA, 4, 948, 10.1017/S1355838298980177 Kuhn, 1996, Xenopus poly(A) binding protein, J. Mol. Biol., 256, 20 Larsen, 1980, The structure of poliovirus replicative form, Nucleic Acids Res., 8, 1217, 10.1093/nar/8.6.1217 Lee, 1977, A protein covalently linked to poliovirus genome RNA, Proc. Natl. Acad. Sci. USA, 74, 59, 10.1073/pnas.74.1.59 Molla, 1991, Cell-free, de novo synthesis of poliovirus, Science, 254, 1647, 10.1126/science.1661029 Ostareck-Lederer, 1998, Cytoplasmic regulatory functions of the KH-domain proteins hnRNPs K and E1/E2, Trends Biochem. Sci., 23, 409, 10.1016/S0968-0004(98)01301-2 Parsley, 1997, Poly (rC) binding protein 2 forms a ternary complex with the 5′- terminal sequences of poliovirus RNA and the viral 3CD proteinase, RNA, 3, 1124 Paul, 1998, Protein-primed RNA synthesis by purified poliovirus RNA polymerase, Nature, 393, 280, 10.1038/30529 Pelletier, 1988, Cap-independent translation of poliovirus mRNA is conferred by sequence elements within the 5′ noncoding region, Mol. Cell. Biol., 8, 1103, 10.1128/MCB.8.3.1103 Pilipenko, 1996, Cis-element, oriR, involved in the initiation of (−) strand poliovirus RNA, EMBO J., 15, 5428, 10.1002/j.1460-2075.1996.tb00926.x Racaniello, 1981, Molecular cloning of poliovirus cDNA and determination of the complete nucleotide sequence of the viral genome, Proc. Natl. Acad. Sci. USA, 78, 4887, 10.1073/pnas.78.8.4887 Raju, 1999, In vivo addition of poly(A) tail and AU-rich sequences to the 3′ terminus of the Sindbis virus RNA genome, J. Virol., 73, 2410, 10.1128/JVI.73.3.2410-2419.1999 Rohll, 1994, The 5′-untranslated regions of picornavirus RNAs contain independent functional domains essential for RNA replication and translation, J. Virol., 68, 4384, 10.1128/JVI.68.7.4384-4391.1994 Rohll, 1995, The 3′ untranslated region of picornavirus RNA, J. Virol., 69, 7835, 10.1128/JVI.69.12.7835-7844.1995 Sachs, 1993, Poly(A) tail metabolism and function in eucaryotes, J. Biol. Chem., 268, 22955, 10.1016/S0021-9258(19)49408-8 Sachs, 1987, A similar domain of yeast poly (A)–binding protein is necessary and sufficient for RNA binding and cell viability, Mol. Cell. Biol., 7, 3268, 10.1128/MCB.7.9.3268 Sachs, 1997, Starting at the beginning, middle, and end, Cell, 89, 831, 10.1016/S0092-8674(00)80268-8 Sarnow, 1989, Role of 3′-end sequences in infectivity of poliovirus transcripts made in vitro, J. Virol., 63, 467, 10.1128/JVI.63.1.467-470.1989 Silvera, 1999, The N-terminal K homology domain of the poly(rC)-binding protein is a major determinant for binding to the poliovirus 5′-untranslated region and acts as an inhibitor of viral translation, J. Biol. Chem., 274, 38163, 10.1074/jbc.274.53.38163 Simoes, 1991, An RNA hairpin at the extreme 5′ end of the poliovirus RNA genome modulates viral translation in human cells, J. Virol., 65, 913, 10.1128/JVI.65.2.913-921.1991 Spagnolo, 2000, Host protein interactions with the 3′ end of bovine coronavirus RNA and the requirement of the poly(A) tail for coronavirus defective genome replication, J. Virol., 74, 5053, 10.1128/JVI.74.11.5053-5065.2000 Spector, 1975, Studies on the function of polyadenylic acid on poliovirus RNA, Cell, 6, 41, 10.1016/0092-8674(75)90071-9 Todd, 1997, Replication-competent picornaviruses with complete genomic RNA 3′ noncoding region deletions, J. Virol., 71, 8868, 10.1128/JVI.71.11.8868-8874.1997 Trono, 1988, Translation in mammalian cells of a gene linked to the poliovirus 5′ noncoding region, Science, 241, 445, 10.1126/science.2839901 Tsai, 1999, Sufficient length of a poly(A) tail for the formation of a potential pseudoknot is required for efficient replication of bamboo mosaic potexvirus RNA, J. Virol., 73, 2703, 10.1128/JVI.73.4.2703-2709.1999 Wang, 1999, An mRNA stability complex functions with poly(A)-binding protein to stabilize mRNA in vitro, Mol. Cell. Biol., 19, 4552, 10.1128/MCB.19.7.4552 Wells, 1998, Circularization of mRNA by eukaryotic translation initiation factors, Mol. Cell, 2, 135, 10.1016/S1097-2765(00)80122-7 Yogo, 1972, Polyadenylic acid at the 3′-terminus of poliovirus RNA, Proc. Natl. Acad. Sci. USA, 69, 1877, 10.1073/pnas.69.7.1877 You, 1999, A novel in vitro replication system for Dengue virus. Initiation of RNA synthesis at the 3′-end of exogenous viral RNA templates requires 5′- and 3′-terminal complementary sequence motifs of the viral RNA, J. Biol. Chem., 274, 33714, 10.1074/jbc.274.47.33714 Yu, 2000, A stem-loop motif formed by the immediate 5′ terminus of the bovine viral diarrhea virus genome modulates translation as well as replication of the viral RNA, J. Virol., 74, 5825, 10.1128/JVI.74.13.5825-5835.2000