2010, Instituto Nacional de Estadística Geografía e Informática
Davington, 2004, Role of endothelial dysfunction in atherosclerosis, Circulation, 109, III27
Lerman, 2005, Endothelial function: Cardiac events, Circulation, 111, 363, 10.1161/01.CIR.0000153339.27064.14
Madamanchi, 2005, Oxidative stress and vascular disease, Arterioscler Thromb Vasc Biol, 25, 29, 10.1161/01.ATV.0000150649.39934.13
Cai, 1999, The Glu-298Asp (894GT) mutation at exon 7 of the endothelial nitric oxide synthase gene and coronary artery disease, J Mol Med, 77, 511, 10.1007/s001099900020
Wang, 2000, Genotype dependent and cigarette specific effects on endothelial nitric oxide synthase expression and enzyme activity, FEBS Lett, 471, 45, 10.1016/S0014-5793(00)01356-9
Golser, 2003, Functional characterization of Glu298Asp mutant human endothelial nitric oxide synthase purified from a yeast expression system, Nitric oxide, 8, 7, 10.1016/S1089-8603(02)00131-3
Hingorani, 1999, A common variant of the endothelial nitric oxide synthase (Glu298Asp) is a major risk factor for coronary artery disease in the UK, Circulation, 100, 1515, 10.1161/01.CIR.100.14.1515
Antoniades, 2005, Genetic polymorphism on endothelial nitric oxide synthase affects endothelial activation and inflammatory response during the acute phase of myocardial infarction, J Am Coll Cardiol, 46, 1101, 10.1016/j.jacc.2005.05.072
Lembo, 2001, A common variant of endothelial nitric oxide synthase (Glu298Asp) is an independent risk factor for carotid atherosclerosis, 32, 735
Paradossi, 2004, Endothelial function and carotid intima-media thickness in young healthy subjects among endothelial nitric oxide synthase Glu298Asp and T-786C polymorphisms, Stroke, 35, 1305, 10.1161/01.STR.0000126482.86708.37
Vasilakou, 2008, Lack of association between endothelial nitric oxide synthase gene polymorphisms and risk of premature coronary artery disease in the Greek population, Act Cardiol, 63, 609, 10.2143/AC.63.5.2033229
Granath, 2001, Lack of evidence for association between endothelial nitric oxide synthase gene polymorphism and coronary artery disease in the Australian Caucasian population, J Cardiovasc Risk, 8, 235, 10.1097/00043798-200108000-00008
Chi, 2003, CEPH human diversity panel for variants in folate pathway genes MTHFR, MTHFD1, MTRR RFC1, and GCP2, Birth Defects Research (Part A), 67, 545, 10.1002/bdra.10076
Vasquez-Vivar, 1998, Superoxide generation by endothelial nitric oxide synthase: the influence of cofactors, Proc Natl Acad Sci U S A, 95, 9220, 10.1073/pnas.95.16.9220
Graham, 1997, Plasma homocysteine as a risk factor for vascular disease The European Concerted Action Project, JAMA, 277, 1775, 10.1001/jama.1997.03540460039030
Gallagher, 1996, Homocysteine and risk of premature coronary heart disease, Circulation, 94, 2154, 10.1161/01.CIR.94.9.2154
Hum, 1988, Primary structure of a human trifunctional enzyme: Isolation of a cDNA encoding methylenetetrahydrofolate-dehydrogenase, methenyltetrahydrofolate-cyclohydrolase formyltetrahydrofolate synthetase, J Biol Chem, 263, 15946, 10.1016/S0021-9258(18)37540-9
Brody, 2002, Am J Hum Genet, 71, 1207, 10.1086/344213
Prasanann, 2003, Human mitochondrial Ci-tetrahydrofolate synthase: Gene structure, tissue distribution of the mRNA, and immunolocalization in Chinese hamster ovary cells, J Bio Chem, 278, 43178, 10.1074/jbc.M304319200
Casas, 2006, Endothelial nitric oxide synthase gene polymorphisms and cardiovascular disease: A HuGE review, Am J Epidemiol, 164, 921, 10.1093/aje/kwj302
Samani, 2007, Genomewide association analysis of coronary artery disease, N Engl J Med, 357, 443, 10.1056/NEJMoa072366
Zhang, 2012, Pharmacogenetic association of NOS3 variants with cardiovascular disease in patients with hypertension: The GenHAR study, Plos One, 7, e34217, 10.1371/journal.pone.0034217
Poirier, 1999, Polymorphisms of the endothelial nitric oxide synthase gene-no consistent in the ECTIM study, Eur J Clin Invest, 29, 284, 10.1046/j.1365-2362.1999.00451.x
2009, Large scale association analysis of novel genetic loci for coronary artery disease, Arterioscler Thromb Vasc Biol, 29, 774, 10.1161/ATVBAHA.108.181388
Silva-Solessi I, Hidalgo MA, Estrada Gil J, Fernández LJC, Figueroa UA, Contreras A. Análisis de la diversidad genómica en las poblaciones mestizas mexicanas para desarrollar medicina genómica en México. 2007 [consultado 17 Mar 2014]. Disponible en: http://www.pnas.org/cgi/doi/10.1073/pnas.0903045106
Stephan, 2012, 2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS guideline for the diagnosis and management of patients with stable ischemic heart disease, Circulation, 126, e354, 10.1161/CIR.0b013e318277d6a0
Christopher, 2013, 2013 ACCF/AHA key data elements and definitions for measuring the clinical management and outcomes of patients with acute coronary syndromes and coronary artery disease, Circulation, 127, 1052, 10.1161/CIR.0b013e3182831a11
González-Herrera, 2010, Forensic parameters and genetic variation of 15 autosomal STR Loci in Mexican Mestizo populations from the State of Yucatan and Nayarit, Open Forensic Sci J, 3, 57, 10.2174/1874402801003010057
Bunce, 2000, PCR-SSP typing, 362
Hibi, 1998, Endothelial nitric oxide synthase gene polymorphism and acute myocardial infarction, Hypertension, 32, 521, 10.1161/01.HYP.32.3.521
Tanus-Santos, 2001, Effects of ethnicity on the distribution of clinically relevant endothelial nitric oxide variants, Pharmacogenetics, 11, 719, 10.1097/00008571-200111000-00011
Rosas-Vargas, 2003, Endothelial nitric oxide synthase gene polymorphism in the Indian and Mestizo populations of Mexico, Hum Biol, 75, 91, 10.1353/hub.2003.0027
Jokiæ, 2011, Association of MTHFR, MTR, MTRR RFC1, and DHFR gene polymorphisms with susceptibility to sporadic colon cancer, DNA Cell Biol, 30, 771, 10.1089/dna.2010.1189
Cann, 2002, A human genome diversity cell line panel, Science, 296, 261, 10.1126/science.296.5566.261b
Shi, 2003, Genotype frequencies and linkage disequilibrium in the CEPH human diversity panel for variants in folate pathway genes MTHFR, MTHFD, MTRR RFC1, and GCP2, Birth Defects Res A Clin Mol Teratol, 67, 545, 10.1002/bdra.10076
García-Castillo, 2005, RENASICA II. Registro Mexicano de Síndromes Coronarios Agudos, Arch Cardiol México, 75, S6
Arroyo, 2007, Obesidad, morfología corporal y presión arterial en grupos urbanos y rurales de Yucatán, Salud Pública de México, 49, 274, 10.1590/S0036-36342007000400007
Encuesta Nacional de Salud y Nutrición 2012. Resultados por entidad federativa. Yucatán. Instituto Nacional de Salud Pública. México [consultado 18 Mar 2014]. Disponible en: http://www.encuestas.insp.mx/
Vargas-Ancona, 1994, Epidemiología de la diabetes mellitus, intolerancia a la glucosa y factores de riesgo aterogénicos en Yucatán, México, Rev Invest Clin, 5, 151
Yamada, 2002, Prediction of the risk ok myocardial infarction from polymorphisms in candidate genes, N Engl J Med, 347, 1916, 10.1056/NEJMoa021445
Luo, 2014, Endothelial nitric oxide synthase gene G894T polymorphism and myocardial infarction: A meta-analysis of 34 studies involving 21068 subjects, PLoS ONE, 9, 87196, 10.1371/journal.pone.0087196
Isordia-Salas, 2010, The Glu298Asp polymorphism of the endothelial nitric oxide synthase gene is associated with premature ST elevation myocardial infarction in Mexican population, Clin Chim Acta, 411, 553, 10.1016/j.cca.2010.01.013
Fairchild, 2001, Acidic hydrolysis as a mechanism for the cleavage of the Glu(298)>Asp variant of human endothelial nitric-oxide synthase, J Biol Chem, 276, 26674, 10.1074/jbc.M103647200
McDonald, 2004, Functional comparison of the endothelial nitric oxide synthase Glu298Asp polymorphic variants in human endothelial cells, Pharmacogenetics, 14, 831, 10.1097/00008571-200412000-00006
Joshi, 2007, Biochemical consequences of the NOS3 Glu298Asp variation in human endothelium: Altered caveolar localization and impaired response to shear, FASEB J, 21, 2655, 10.1096/fj.06-7088com
Chen, 2012, Nitric oxide-dependent Src activation and resultant caveolin-1 phosphorylation promote eNOS/caveolin-1 binding and NOS inhibition, Mol Biol Cell, 23, 1388, 10.1091/mbc.E11-09-0811
Fleming, 2003, Molecular mechanisms involved in the regulation of the endothelial nitric oxide synthase, AmJ Physiol Regul Integr Com Physiol, 284, R1, 10.1152/ajpregu.00323.2002
Boo, 2006, Coordinated regulation of endothelial nitric oxide synthase activity by phosphorylation and subcellular localization, Free Radic Biol Med, 411, 44
Modrego, 2013, Platelet content of nitric oxide synthase 3 phosphorylated at serine1177 is associated with the functional response of platelets to aspirin, PLoS ONE, 8, e82574, 10.1371/journal.pone.0082574
Qian, 2013, Post-translational regulation of endothelial nitric oxide synthase in vascular endothelium, Frontier in Physiology, 4, 1
Han, 2012, 17β-estradiol antagonizes the down-regulation of ERα/NOS-3 signaling in vascular endothelial dysfunction of female diabetic rats, PLoS ONE, 7, e50402, 10.1371/journal.pone.0050402
Matsa, 2013, Haplotypes of NOS3 gene polymorphisms in dilated cardiomyopathy, PLoS ONE, 8, e70523, 10.1371/journal.pone.0070523
Colombo, 2003, Endothelial nitric oxide synthase gene polymorphisms and risk of coronary artery disease, Clin Chem, 49, 389, 10.1373/49.3.389
2007, Genome-wide association study of 14 000 cases of seven common diseases and 3 000 shared controls, Nature, 447, 661, 10.1038/nature05911
Bressler, 2010, Genetic variants identified in a European Genome-Wide Association Study that were found to predict incident coronary heart disease in the atherosclerosis risk in communities study, Am J Epidemiol, 171, 14, 10.1093/aje/kwp377