Platelet-rich plasma promotes epithelialization and angiogenesis in a splitthickness skin graft donor site

Natsuko Kakudo1, Satoshi Kushida1, Tatsuya Minakata1, Kenji Suzuki1, Kenji Kusumoto1
1Department of Plastic and Reconstructive Surgery, Kansai Medical University, Moriguchi, Japan

Tóm tắt

Từ khóa


Tài liệu tham khảo

Marx RE (2004) Platelet-rich plasma: evidence to support its use. J Oral Maxillofac Surg 62:489–496

Margolis DJ, Kantor J, Santanna J, Strom BL, Berlin JA (2001) Effectiveness of platelet releasate for the treatment of diabetic neuropathic foot ulcers. Diabetes Care 24:483–488

Marx RE, Carlson ER, Eichstaedt RM, Schimmele SR, Strauss JE, Georgeff KR (1998) Platelet-rich plasma: growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 85:638–646

Bhanot S, Alex JC (2002) Current applications of platelet gels in facial plastic surgery. Facial Plast Surg 18:27–33

Man D, Plosker H, Winland-Brown JE (2001) The use of autologous platelet-rich plasma (platelet gel) and autologous plateletpoor plasma (fibrin glue) in cosmetic surgery. Plast Reconstr Surg 107:229–223

Hee HT, Majd ME, Holt RT, Myers L (2003) Do autologous growth factors enhance transforaminal lumbar interbody fusion? Eur Spine 12:400–407

Eppley BL, Pietrzak WS, Blanton M (2006) Platelet-rich plasma: a review of biology and applications in plastic surgery. Plast Reconstr Surg 118:147e–159e

Kakudo N, Minakata T, Mitsui T, Kushida S, Notodihardjo FZ, Kusumoto K (2008) Proliferation-promoting effect of platelet-rich plasma on human adipose-derived stem cells and human dermal fibroblasts. Plast Reconstr Surg 122:1352–1360

Danielsen P, Jørgensen B, Karlsmark T, Jorgensen LN, Agren MS (2008) Effect of topical autologous platelet-rich fibrin versus no intervention on epithelialization of donor sites and meshed splitthickness skin autografts: a randomized clinical trial. Plast Reconstr Surg 22:1431–1440

The World Medical Association (website) (2010) World Medical Association Declaration of Helsinki. Available at: http://www.wma.net/en/30publications/10policies/b3/index.html . Accessed August 1, 2010

Kakudo N, Kushida S, Kusumoto K (2009) Platelet-rich plasma: the importance of platelet separation and concentration. Plast Reconstr Surg 123:1135–1136

Kakudo N, Kusumoto K, Wang YB, Iguchi Y, Ogawa Y (2006) Immunolocalization of vascular endothelial growth factor on intramuscular ectopic osteoinduction by bone morphogenetic protein-2. Life Sci 79:1847–1855

Broughton G II, Janis JE, Attinger CE (2006) Wound healing: an overview. Plast Reconstr Surg 117(suppl 7):1e-S–32e-S

Smith SE, Roukis TS (2009) Bone and wound healing augmentation with platelet-rich plasma. Clin Podiatr Med Surg 26:559–588

Kazakos K, Lyras DN, Verettas D, Tilkeridis K, Tryfonidis M (2009) The use of autologous PRP gel as an aid in the management of acute trauma wounds. Injury 40:801–805

Kurokawa I, Mizutani H, Kusumoto K, Nishijima S, Tsujita-Kyutoku M, Shikata N, Tsubura A (2006) Cytokeratin, filaggrin, and p63 expression in reepithelialization during human cutaneous wound healing. Wound Repair Regen 14:38–45

Zheng Q, Choi J, Rouleau L, Leask RL, Richardson JA, Davis EC, Yanagisawa H (2006) Normal wound healing in mice deficient for fibulin-5, an elastin binding protein essential for dermal elastic fiber assembly. J Invest Dermatol 126:2707–2714

Moiemen NS, Staiano JJ, Ojeh NO, Thway Y, Frame JD (2001) Reconstructive surgery with a dermal regeneration template: clinical and histologic study. Plast Reconstr Surg 108:93–103