Platelet-rich plasma (PRP) for knee disorders

EFORT Open Reviews - Tập 2 Số 2 - Trang 28-34 - 2017
Mohammad Shahid1,2, Rik Kundra1,2
1St Michael’s Hospital, 30 Bond Street, Toronto, M5B1W8, Canada
2Walsall Manor Hospital, Moat Road, Walsall, WS2 9PS, UK

Tóm tắt

Platelet-rich plasma (PRP) is an autologous blood product with platelet concentrations above baseline values. The process involves the extraction of blood from the patient which is then centrifuged to obtain a concentrated suspension of platelets by plasmapheresis. It then undergoes a two-stage centrifugation process to separate the solid and liquid components of the anticoagulated blood. PRP owes its therapeutic use to the growth factors released by the platelets which are claimed to possess multiple regenerative properties. In the knee, PRP has been used in patients with articular cartilage pathology, ligamentous and meniscal injuries. There is a growing body of evidence to support its use in selected indications and this review looks at the most recent evidence. We also look at the current UK National Institute of Health & Clinical Excellence (NICE) guidelines with respect to osteoarthritis and the use of PRP in the knee.Cite this article: EFORT Open Rev 2017;2:28–34. DOI: 10.1302/2058-5241.2.160004.

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EFORT Open Reviews

Tập 2 Số 2

28-34

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