Platelet function during cardiac surgery and cardiopulmonary bypass with low-dose aprotinin

Campbell, 1991, The contribution of platelet dysfunction on postbypass bleeding, J Cardiothorac Anesth, 5, 8, 10.1016/1053-0770(91)90080-D Mohr, 1986, Effect of cardiac operation on platelets, J Thorac Cardiovasc Surg, 92, 434, 10.1016/S0022-5223(19)35797-6 Kestin, 1993, The platelet function defect of cardiopulmonary bypass, Blood, 82, 107, 10.1182/blood.V82.1.107.bloodjournal821107 Bidstrup, 1993, Aprotinin therapy in cardiac operations: A report on use in cardiac centers in United Kingdom, Ann Thorac Surg, 55, 971, 10.1016/0003-4975(93)90128-5 Blauhut, 1991, Effects of high-dose aprotinin on blood loss, platelet function, fibrinolysis, complement, and renal function after cardiopulmonary bypass, J Thorac Cardiovasc Surg, 101, 958, 10.1016/S0022-5223(19)36611-5 Royston, 1992, High-dose aprotinin therapy: A review of the first five years' experience, J Cardiothorac Anesth, 6, 76, 10.1016/1053-0770(91)90052-U Bode, 1989, The use of thrombin inhibitors and aprotinin in the preservation of platelets stored for transfusion, J Lab Clin Med, 113, 753 van Oeveren, 1990, Aprotinin protects platelets against the initial effect of cardiopulmonary bypass, J Thorac Cardiovasc Surg, 99, 788, 10.1016/S0022-5223(19)36893-X Lavee, 1993, Platelet protection by low-dose aprotinin in cardiopulmonary bypass: Electron microscopic study, Ann Thorac Surg, 55, 114, 10.1016/0003-4975(93)90484-Y van Oeveren, 1987, Effects of aprotinin on hemostatic mechanisms during cardiopulmonary bypass, Ann Thorac Surg, 44, 640, 10.1016/S0003-4975(10)62153-4 Boldt, 1993, Platelet function in cardiac surgery: Influence of temperature and aprotinin, Ann Thorac Surg, 55, 652, 10.1016/0003-4975(93)90269-N Carrel, 1991, Low-dose aprotinin also allows reduction of blood loss after cardiopulmonary bypass, J Thorac Cardiovasc Surg, 102, 801, 10.1016/S0022-5223(19)36879-5 Kawasuji, 1993, Effect of low-dose aprotinin on coagulation and fibrinolysis in cardiopulmonary bypass, Ann Thorac Surg, 55, 1205, 10.1016/0003-4975(93)90035-G Schönberger, 1992, Low-dose aprotinin in internal mammary artery bypass operations contributes to important blood saving, Ann Thorac Surg, 54, 1172, 10.1016/0003-4975(92)90089-M Alajmo, 1989, High-dose aprotinin: Hemostatic effects in open-heart operations, Ann Thorac Surg, 48, 536, 10.1016/S0003-4975(10)66857-9 Cosgrove, 1992, Aprotinin therapy for reoperative myocardial revascularization, Ann Thorac Surg, 54, 1031, 10.1016/0003-4975(92)90066-D Covino, 1991, Low-dose aprotinin as blood saver in open-heart surgery, Eur J Cardiothorac Surg, 5, 414, 10.1016/1010-7940(91)90186-N Alvarez, 1995, The use of ultra-low-dose aprotinin to reduce blood loss in cardiac surgery, J Cardiothorac Vasc Anesth, 9, 29, 10.1016/S1053-0770(05)80052-7 Born, 1962, Aggregation of blood platelets by adenosine diphosphate and its reversal, Nature, 163, 927, 10.1038/194927b0 Levy, 1994, Pharmacokinetics of aprotinin in preoperative cardiac surgical patients, Anesthesiology, 80, 1013, 10.1097/00000542-199405000-00010 Cramer, 1991, Differential redistribution of platelet glycoproteins Ib and IIb/IIIa after plasmin stimulation, Blood, 77, 694, 10.1182/blood.V77.4.694.694 Matzdorff, 1993, Effect of recombinant aprotinin on platelet activation in patients undergoing open-heart surgery, Haemostasis, 23, 293 Isetta, 1992, Aprotinin treatment in cardiac surgery: Low dose versus high dose, Anesthesiology, 77, A139, 10.1097/00000542-199209001-00139 Carrel, 1991, Low-dose aprotinin for reduction of blood loss after cardiopulmonary bypass, Lancet, 337, 673, 10.1016/0140-6736(91)92485-K Blanco, 1994, Efectos de la aprotinina a dosis bajas en cirugia cardiaca, Rev Esp Anestesiol Reanim, 41, 168 Dietrich, 1992, High-dose aprotinin in cardiac surgery: Three years' experience in 1784 patients, J Cardiothorac Anesth, 6, 324, 10.1016/1053-0770(92)90150-6 Bidstrup, 1989, Reduction in blood loss and blood use after cardiopulmonary bypass with high-dose aprotinin (Trasylol), J Thorac Cardiovasc Surg, 97, 364, 10.1016/S0022-5223(19)34573-8 Corash, 1990, Measurement of platelet activation by fluorescence-activated flow cytometry, Blood Cells, 160, 97 Ginsberg, 1990, Analysis of platelet aggregation disorders based on flow cytometric analysis of membrane glycoprotein IIb-IIIa with conformation-specific monoclonal antibodies, Blood, 76, 2017, 10.1182/blood.V76.10.2017.2017 John, 1993, Reduction of heparin binding to and inhibition of platelets by aprotinin, Ann Thorac Surg, 55, 1175, 10.1016/0003-4975(93)90029-H Santa Ursula, 1991, Variacion plaquetaria durante la cirugia cardiaca con circulacion extracorpórea, Rev Esp Anestesiol Reanim, 38, 98 Merin, 1975, The influence of cardiopulmonary bypass on the size of human platelets, J Thorac Cardiovasc Surg, 70, 727, 10.1016/S0022-5223(19)40305-X Martinowitz, 1990, Is transfusion of fresh plasma after cardiac operations indicated?, J Thorac Cardiovasc Surg, 100, 92, 10.1016/S0022-5223(19)35603-X Harker, 1980, Mechanism of abnormal bleeding in patients undergoing cardiopulmonary bypass: Acquired transient platelet dysfunction associated with selective alpha-granule release, Blood, 56, 824 Rinder, 1991, Platelet activation and aggregation during cardiopulmonary bypass, Anesthesiology, 75, 388, 10.1097/00000542-199109000-00002 Edmunds, 1982, Platelet function during cardiac operation, J Thorac Cardiovasc Surg, 83, 805, 10.1016/S0022-5223(19)37175-2 Wachtfogel, 1985, Loss of platelet alpha4-adrenergic receptors during simulated extracorporeal circulation: Prevention with prostaglandin E1, J Lab Clin Med, 105, 601 Orchard, 1993, Aprotinin reduces cardiopulmonary bypass-induced blood loss and inhibits fibrinolysis without influencing platelets, Br J Haematol, 85, 533, 10.1111/j.1365-2141.1993.tb03344.x Wahba, 1996, Aprotinin has no effect on platelet activation and adhesion during cardiopulmonary bypass, Thromb Haemost, 75, 844, 10.1055/s-0038-1650377 Boldt, 1994, Influence of different anticoagulation regimens on platelet function during cardiac surgery, Br J Anaesth, 73, 639, 10.1093/bja/73.5.639 Escolar, 1991, The platelet open canalicular system: A final common pathway, Blood Cells, 17, 467 Addonizio, 1979, Thromboxane synthesis and platelet protein release during simulated extracorporeal circulation, Blood, 54, 371 Najman, 1993, Effects of aprotinin on anticoagulant monitoring: Implications in cardiovascular surgery, Ann Thorac Surg, 55, 662, 10.1016/0003-4975(93)90272-J