Plasmodium falciparum glycogen synthase kinase-3: molecular model, expression, intracellular localisation and selective inhibitors

Eliane Droucheau1, Aline Primot1, Virginie Thomas1, Denise Mattei2, Marie Knockaert1, Chris Richardson3, Pina Sallicandro4, Pietro Alano4, Ali Jafarshad5, Blandine Baratte1, Conrad Kunick6, Daniel Parzy7, Laurence Pearl3, Christian Doerig5, Laurent Meijer1
1C.N.R.S., Cell Cycle Group, Station Biologique, B.P. 74, 29682 Roscoff cedex, Bretagne, France
2Unité de Biologie des Interactions Hôte-Parasite, Institut Pasteur, 25, rue du Docteur Roux, 75724 Paris cedex 15, France
3Section of Structural Biology, Institute of Cancer Research, Chester Beatty Laboratories, London SW3 6JB, UK
4Laboratorio di Biologia Cellulare, Istituto Superiore di Sanita, Viale Regina Elena 299, Roma 0161, Italy
5INSERM U511 Team, Wellcome Centre of Molecular Parasitology, The Anderson College, 56 Dumbarton Road, Glasgow G11 6NU, Scotland, UK
6Institut für Pharmazie, Universität Hamburg, Bundesstraße 45, D-20146-Hamburg, Germany
7Institut de Médecine Tropicale du Service de Santé des Armées, Le Pharo, Marseille, France

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