Plasma glutathione of HIV+ patients responded positively and differently to dietary supplementation with cysteine or glutamine

Nutrition - Tập 28 Số 7-8 - Trang 753-756 - 2012
Maria Dorotéia Borges‐Santos1, Fernando Moreto2, Paulo Câmara Marques Pereira3, Yong Ming‐Yu4, Roberto Carlos Burini1
1Department of Public Health, Botucatu Medical School, UNESP–São Paulo State University, Botucatu, São Paulo, Brazil
2Department of Pathology, Botucatu Medical School, UNESP—São Paulo State University, Botucatu, São Paulo, Brazil
3Department of Infectious Diseases, Botucatu Medical School, UNESP–São Paulo State University, Botucatu, São Paulo, Brazil
4MGH Surgery, Shiners Burns Hospital, Boston, Massachusetts, USA

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Jones, 2006, Micronutrient levels and HIV disease status in HIV-infected patients on highly active antiretroviral therapy in the Nutrition for Healthy Living cohort, J Acquir Immune Defic Syndr, 43, 475, 10.1097/01.qai.0000243096.27029.fe

Lanzillotti, 2005, Micronutrients and HIV disease: a review pre- and post-HAART, Nutr Clin Care, 8, 16

Patrick, 2000, Nutrients and HIV: part three—N-acetylcysteine, alpha-lipoic acid, L-glutamine, and L-carnitine, Altern Med Rev, 5, 290

Bogden, 2000, Status of selected nutrients and progression of human immunodeficiency virus type 1 infection, Am J Clin Nutr, 72, 809, 10.1093/ajcn/72.3.809

Pitts, 1995, Con A cytotoxicity: a model for the study of key signaling steps leading to lymphocyte apoptosis in AIDS?, Med Hypothesis, 45, 311, 10.1016/0306-9877(95)90123-X

Meister, 1988, Glutathione metabolism and its selective modification, J Biol Chem, 263, 17205, 10.1016/S0021-9258(19)77815-6

Dröge, 1991, Modulation of lymphocyte functions and immune responses by cysteine and cysteine derivatives, Am J Med, 91, 10.1016/0002-9343(91)90297-B

Griffith, 1999, Biologic and pharmacologic regulation of mammalian glutathione synthesis, Free Radic Biol Med, 27, 922, 10.1016/S0891-5849(99)00176-8

Fukagawa, 1996, Plasma methionine and cysteine kinetics in response to an intravenous glutathione infusion in adult humans, Am J Physiol Endocrinol Metab, 270, E209, 10.1152/ajpendo.1996.270.2.E209

Sen, 2001, Antioxidant and redox regulation of cellular signaling: introduction, Med Sci Sports Exerc, 33, 368, 10.1097/00005768-200103000-00005

Angelini, 2002, Antigen-presenting dendritic cells provide the reducing extracellular microenvironment required for T lymphocyte activation, Proc Natl Acad Sci U S A, 99, 1491, 10.1073/pnas.022630299

Dröge, 2002, Free radicals in the physiological control of cell function, Physiol Rev, 82, 47, 10.1152/physrev.00018.2001

Sen, 2000, Thiol homeostasis and supplements in physical exercise, Am J Clin Nutr, 72, 10.1093/ajcn/72.2.653S

Reid, 2000, In vivo rates of erythrocyte glutathione synthesis in children with severe protein–energy malnutrition, Am J Physiol Endocrinol Metab, 278, E405, 10.1152/ajpendo.2000.278.3.E405

Atkuri, 2007, N-acetylcysteine: a safe antidote for cysteine/glutathione deficiency, Curr Opin Pharmacol, 7, 355, 10.1016/j.coph.2007.04.005

Valencia, 2002, Impact of oral L-glutamine on glutathione, glutamine, and glutamate blood levels in volunteers, Nutrition, 18, 367, 10.1016/S0899-9007(02)00774-8

Halawa, 1991, Use of high performance liquid chromatography in defining the abnormalities in the free amino acid patters in the cerebrospinal fluid of patients with aseptic meningitis, Biomed Chromatogr, 5, 216, 10.1002/bmc.1130050508

Ubbink, 1991, Rapid high-performance liquid chromatographic assay for total homocysteine levels in human serum, J Chromatogr, 565, 441, 10.1016/0378-4347(91)80407-4

Paroni, 1995, HPLC with o-phthalaldehyde precolumn derivatization to measure total, oxidized, and protein-bound glutathione in blood, plasma, and tissue, Clin Chem, 41, 448, 10.1093/clinchem/41.3.448

Borges-Santos, 2004, Deficiência antioxidante em pacientes HIV+, uma deficiência global ou específica de nutrientes?, Rev Bras Nutr Clin, 19, 178

Jahoor, 1999, Erythrocyte glutathione deficiency in symptom-free HIV infection is associated with decreased synthesis rate, Am J Physiol Endocrinol Metab, 276, E205, 10.1152/ajpendo.1999.276.1.E205

Aukrust, 2003, Disturbed glutathione metabolism and decreased antioxidant levels in human immunodeficiency virus-infected patients during highly active antiretroviral therapy—potential immunomodulatory effects of antioxidants, J Infect Dis, 188, 232, 10.1086/376459

Helbling, 1996, Decreased release of glutathione into the systemic circulation of patients with HIV infection, Eur J Clin Invest, 26, 38, 10.1046/j.1365-2362.1996.88237.x

Jones, 2011, Dietary sulfur amino acid effects on fasting plasma cysteine/cystine redox potential in humans, Nutrition, 27, 199, 10.1016/j.nut.2010.01.014

Grimble, 2005, Immunonutrition, Curr Opin Gastroenterol, 21, 216, 10.1097/01.mog.0000153360.90653.82

Hack, 1997, Cystine levels, cystine flux, and protein catabolism in cancer cachexia, HIV/SIV infection, and senescence, FASEB J, 11, 84, 10.1096/fasebj.11.1.9034170

Dröge, 1997, Role of cysteine and glutathione in HIV infection and other diseases associated with muscle wasting and immunological dysfunction, FASEB J, 11, 1077, 10.1096/fasebj.11.13.9367343

Dröge, 1997, Role of cysteine and glutathione in HIV infection and cancer cachexia: therapeutic intervention with N-acetylcysteine, Adv Pharmacol, 38, 581, 10.1016/S1054-3589(08)61000-5

Stipanuk, 2004, Sulfur amino acid metabolism: pathways for production and removal of homocysteine and cysteine, Annu Rev Nutr, 24, 539, 10.1146/annurev.nutr.24.012003.132418

Jackson, 1991, The glycine story, Eur J Clin Nutr, 45, 59

Friesen, 2007, Relationship of dimethylglycine, choline, and betaine with oxoproline in plasma of pregnant women and their newborn infants, J Nutr, 137, 2641, 10.1093/jn/137.12.2641

Lamers, 2007, Glycine turnover and decarboxylation rate quantified in healthy men and women using primed, constant infusions of [1,2-(13)C2]glycine and [(2)H3]leucine, J Nutr, 137, 2647, 10.1093/jn/137.12.2647