Pirfenidone in patients with progressive fibrotic interstitial lung diseases other than idiopathic pulmonary fibrosis (RELIEF): a double-blind, randomised, placebo-controlled, phase 2b trial

Lancet Respiratory Medicine,The - Tập 9 Số 5 - Trang 476-486 - 2021
Jürgen Behr1,2, Antje Prasse3, Michael Kreuter4, Johannes Johow5, Klaus F. Rabe6, Francesco Bonella7, R. Bonnet8, Christian Grohé9, Matthias Held10, Heinrike Wilkens11, Peter Hammerl12, Dirk Koschel13, Stefan Blaas14, Hubert Wirtz15, Joachim H. Ficker16, Wolfgang Neumeister17, Nicolas Schönfeld18, Martin Claussen6, Nikolaus Kneidinger2, Marion Frankenberger19,20, Simone Hummler4, Nicolas Kahn4, Silke Tello21, Julia Freise3, Tobias Welte3, Petra Neuser5, Andreas Günther21,22, N Schönfeld18, Carmen Schade‐Brittinger, Behnaz Aminossadati, Christian Nasemann9, Soraya Yahiaoui, Christoph Dupuy Backofen, Maik Hahmann, Michael Wittenberg4, Fotios Drakopanagiotakis, Daniel von der Beck, Sedigheh Ghofrani, S Heinemann, Ekaterina Krauss, Hella Rethorn, Andrea Koch21,22, Gabriela Leuschner, Sandhya Matthes, Claus Neurohr6, Tobias Veit3, Katrin Milger, Felix Herth, Julia Benstz3, Thomas Bahmer, Heike Biller, Benjamin Waschki, Rosa-Marie Apel, Ulrich Costabel, Eva Börner, Thomas Wessendorf, M Arnrich, Lacramioara Ilie, Alexandra Wald, Hans‐Jürgen Seyfarth, Christian Reinhardt9, Atif Cinar, Markus Vogler, Siegfried Matthias Huhn, Jaqueline Richter, U Neff, Torsten Blum, Silvan Vesenbeckh, Christian Boch9, Hannes Semper5, Andreas Wilke11, Roman Pfeifer4, Annette Schweda, Angelika Krill, Christian Lensch9, F Joa16, Barbara Schröder, Annabel Plaßmeier, Stefan Baron14, Klaus Peter Froehling
1Asklepios Lung Center Gauting, DZL, Munich, Germany
2Department of Internal Medicine V, University Hospital, Ludwig Maximilian University (LMU) Munich, Member of the German Center for Lung Research (DZL), Munich, Germany
3Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover Medical School, Hannover, Germany
4Center for Interstitial And Rare Lung Diseases, Department of Pneumology, Thoraxklinik Heidelberg University Hospital, Heidelberg, Germany
5Coordinating Center for Clinical Trials, Philipps University Marburg, Marburg, Member of the German Center for Lung Research, Germany
6Lung Clinic Grosshansdorf, Grosshansdorf, Germany
7Department of Pulmonary Medicine, Ruhrlandklinik, University Essen, Essen, Germany
8Zentralklinik Bad Berka, Department of Pulmonary Medicine, Bad Berka, Germany
9Protestantic Lung Clinic Berlin, Berlin, Germany
10Department of Pulmonary Medicine, KWM Missio Clinic, Würzburg, Würzburg, Germany
11Department of Pulmonary Medicine, Saarland University Medical Center, Homburg, Germany
12Lung Clinic Immenhausen, Immenhausen, Germany
13Lung Clinic Coswig, University Carl Gustav Carus Dresden, Dresden, Germany
14Donaustauf Hospital, Center for Pneumology, Donaustauf, Germany
15Department of Pulmonary Medicine, University Hospital Leipzig, Leipzig, Germany
16Paracelsus Medical University Nuernberg, Nuernberg General Hospital, Nuernberg, Germany
17Department of Pulmonary Medicine, Catholic Clinic Koblenz Montabaur, Koblenz, Germany
18Helios Klinikum Emil von Behring, Lungenklinik Heckeshorn, Berlin, Germany
19Asklepios Clinic Gauting, Munich, Germany
20Comprehensive Pneumology Center, Helmholtz Center Munich, Ludwig Maximilian University Munich, Munich, Germany
21Center for Interstitial and Rare Lung Diseases, Justus-Liebig University Giessen, Giessen, Germany
22Member of the German Center for Lung Research and Cardiopulmonary Institute, and Agaplesion Lung Clinic Waldhof-Elgershausen, Greifenstein, Germany

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Lancet Respiratory Medicine,The

Tập 9 Số 5

476-486

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