Pigment epithelium-derived factor stimulates skeletal muscle glycolytic activity through NADPH oxidase-dependent reactive oxygen species production

Revathy Carnagarin1,2,3,4, Rodrigo Carlessi1,4, Philip Newsholme1,4, Arun M. Dharmarajan1,3, Crispin R. Dass1,2
1Curtin Health Innovation Research Institute, Bentley, 6102, Australia
2School of Pharmacy, Curtin University, Bentley 6102, Australia
3Stem Cell and Cancer Biology Laboratory, School of Biomedical Sciences, Curtin University, Bentley, 6102, Australia
4School of Biomedical Sciences, Curtin University, Bentley, 6102, Australia

Tài liệu tham khảo

Alcantara, 2014, Pigment epithelium-derived factor as a natural matrix metalloproteinase inhibitor: a comparison with classical matrix metalloproteinase inhibitors used for cancer treatment, J. Pharm. Pharmacol., 66, 895, 10.1111/jphp.12218 Benigni, 2000, The proinflammatory mediator macrophage migration inhibitory factor induces glucose catabolism in muscle, J. Clin. Invest., 106, 1291, 10.1172/JCI9900 Borg, 2011, Pigment epithelium-derived factor regulates lipid metabolism via adipose triglyceride lipase, Diabetes, 60, 1458, 10.2337/db10-0845 Brand, 1997, Aerobic glycolysis by proliferating cells: a protective strategy against reactive oxygen species, FASEB J., 11, 388, 10.1096/fasebj.11.5.9141507 Carnagarin, 2015, PEDF-induced alteration of metabolism leading to insulin resistance, Mol. Cell. Endocrinol., 401, 98, 10.1016/j.mce.2014.11.006 Carnagarin, 2016, PEDF attenuates insulin-dependent molecular pathways of glucose homeostasis in skeletal myocytes, Mol. Cell. Endocrinol., 422, 115, 10.1016/j.mce.2015.12.010 Chandel, 1998, Mitochondrial reactive oxygen species trigger hypoxia-induced transcription, Proc. Natl. Acad. Sci. U.S.A., 95, 11715, 10.1073/pnas.95.20.11715 Chen, 2010, Plasma level of pigment epithelium-derived factor is independently associated with the development of the metabolic syndrome in Chinese men: a 10-year prospective study, J. Clin. Endocrinol. Metab., 95, 5074, 10.1210/jc.2010-0727 Chung, 2008, Anti-angiogenic pigment epithelium derivedfactor regulates hepatocyte triglyceride content through adipose triglyceride lipase (ATGL), J. Hepatol., 48, 471, 10.1016/j.jhep.2007.10.012 Colston, 2005, H2O2 activates Nox4 through PLA2-dependent arachidonic acid production in adult cardiac fibroblasts, FEBS Lett., 579, 2533, 10.1016/j.febslet.2005.03.057 Crowe, 2009, Pigment epithelium-derived factor contributes to insulin resistance in obesity, Cell Metab., 10, 40, 10.1016/j.cmet.2009.06.001 Dawson, 1999, Pigment epithelium-derived factor: a potent inhibitor of angiogenesis, Science, 285, 245, 10.1126/science.285.5425.245 Der-Torossian, 2013, Metabolic derangements in the gastrocnemius and the effect of Compound A therapy in a murine model of cancer cachexia, J. Cachexia Sarcopenia Muscle, 4, 145, 10.1007/s13539-012-0101-7 Di Meo, 2001, Mitochondria in exercise-induced oxidative stress, Biol. Signals Recept., 10, 125, 10.1159/000046880 Famulla, 2011, Pigment epithelium-derived factor is one of the most abundant proteins secreted by human adipocytes and induces insulin resistance and inflammatory signaling in muscle and fat cells, Int. J. Obes. (Lond.), 35, 762, 10.1038/ijo.2010.212 Filleur, 2005, Two functional epitopes of pigment epithelial-derived factor block angiogenesis and induce differentiation in prostate cancer, Cancer Res., 65, 5144, 10.1158/0008-5472.CAN-04-3744 Foresti, 2015, Nrf2 activators modulate oxidative stress responses and bioenergetic profiles of human retinal epithelial cells cultured in normal or high glucose conditions, Pharmacol. Res., 99, 296, 10.1016/j.phrs.2015.07.006 Grönke, 2005, Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila, Cell Metab., 1, 323, 10.1016/j.cmet.2005.04.003 Haemmerle, 2006, Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase, Science, 312, 73734, 10.1126/science.1123965 Herrero, 1997, ADP-Regulation of mitochondrial free radical production is different with complex I- or complex II-linked substrates: implications for the exercise paradox and brain hypermetabolism, J. Bioenerg. Biomembr., 29, 241, 10.1023/A:1022458010266 Jackson, 2007, The production of reactive oxygen and nitrogen species by skeletal muscle, J. Appl. Physiol., 102, 1664, 10.1152/japplphysiol.01102.2006 Jenkins, 2004, Identification, cloning, expression, and purification of three novel human calciumin dependent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities, J. Biol. Chem., 279, 48968, 10.1074/jbc.M407841200 Kampfer, 2014, Pigment-Epithelium Derived Factor (PEDF) and the human ovary: a role in the generation of ROS in granulosa cells, Life Sci., 97, 129, 10.1016/j.lfs.2013.12.007 Kozlov, 2005, Skeletal muscles, heart, and lung are the main sources of oxygen radicals in old rats, BBA Mol. Basis Dis., 1740, 382, 10.1016/j.bbadis.2004.11.004 Li, 2002, Essential role of the NADPH oxidase subunit p47phox in endothelial cell superoxide production in response to phorbol ester and tumor necrosis factor-(alpha), Circ. Res., 90, 143, 10.1161/hh0202.103615 Li, 2007, Muscle-derived but not centrally derived transgene GDNF is neuroprotective in G93A-SOD1 mouse model of ALS, Exp. Neurol., 203, 457, 10.1016/j.expneurol.2006.08.028 Matono, 2006, Arachidonic acid induces direct interaction of the p67phox-Rac complex with the phagocyte oxidase Nox2, leading to superoxide production, J. Biol. Chem., 289, 24874, 10.1074/jbc.M114.581785 Nakamura, 2009, Serum levels of pigment epithelium-derived factor (PEDF) are positively associated with visceral adiposity in Japanese patients with type 2 diabetes, Diabetes Metab. Res. Rev., 25, 52, 10.1002/dmrr.820 Nakamura, 2010, Serum levels of pigment epithelium-derived factor (PEDF) are an independent determinant of insulin resistance in patients with essential hypertension, Int. J. Cardiol., 143, 96, 10.1016/j.ijcard.2008.11.169 Nicholls, 2010, Bioenergetic profile experiment using C2C12 myoblast cells, J. Vis. Expt., 46, 2511 Notari, 2006, Identification of a lipase linked cell membrane receptor for pigment epithelium-derived factor, J. Biol. Chem., 281, 38022, 10.1074/jbc.M600353200 Petersen, 2003, Pigment-epithelium-derived-factor (PEDF) occurs at a physiologically relevant concentration in human blood: purification and characterization, Biochem. J., 374, 199, 10.1042/bj20030313 Piao, 2005, Nox 2 stimulates muscle differentiation via NF-κB/iNOS pathway, Free Radic. Biol. Med., 38, 989, 10.1016/j.freeradbiomed.2004.11.011 Powers, 2008, Exercise-induced oxidative stress: cellular mechanisms and impact on muscle force production, Physiol. Rev., 88, 1243, 10.1152/physrev.00031.2007 Remels, 2015, TNF-α-Induced NF-κB activation stimulates skeletal muscle glycolytic metabolism through activation of HIF-1α, Endocrinology, 156, 1770, 10.1210/en.2014-1591 Rychli, 2009, Pigment epithelium-derived factor (PEDF) as a therapeutic target in cardiovascular disease, Expert Opin. Ther. Targets, 13, 1295, 10.1517/14728220903241641 Sabater, 2010, Circulating pigment epithelium-derived factor levels are associated with insulin resistance and decrease after weight loss, J. Clin. Endocrinol. Metab., 95, 4720, 10.1210/jc.2010-0630 Shi, 2015, DJ-1 links muscle ROS production with metabolic reprogramming and systemic energy homeostasis in mice, Nat. Commun., 6, 10.1038/ncomms8415 Smirnova, 2006, ATGL has a key role in lipid droplet/adiposome degradation in mammalian cells, EMBO Rep., 7, 106, 10.1038/sj.embor.7400559 Spitzer, 1989, Altered control of carbohydrate metabolism in endotoxemia, Prog. Clin. Biol. Res., 286, 145 Subramanian, 2010, Pigment epithelium-derived factor receptor (PEDF-R): a plasma membrane-linked phospholipase with PEDF binding affinity, Adv. Exp. Med. Biol., 664, 29, 10.1007/978-1-4419-1399-9_4 Villena, 2004, Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis, J. Biol. Chem., 279, 47066, 10.1074/jbc.M403855200 Yamagishi, 2006, Elevated serum levels of pigment epithelium-derived factor in the metabolic syndrome, J. Clin. Endocrinol. Metab., 91, 2447, 10.1210/jc.2005-2654 Yamagishi, 2010, Pathophysiological role of pigment epithelium-derived factor (PEDF) in hepatic disorders, Curr. Med. Chem., 17, 1995, 10.2174/092986710791233670 Yang, 2011, Serum pigment epithelium-derived factor is elevated in women with polycystic ovary syndrome and correlates with insulin resistance, J. Clin. Endocrinol. Metab., 96, 831, 10.1210/jc.2010-2140 Zhao, 2002, Cytosolic phospholipase A2 (cPLA2) regulation of human monocyte NADPH oxidase activity: cPLA2 affects translocation but not phosphorylation of p67phox and p47phox, J. Biol. Chem., 277, 25385, 10.1074/jbc.M203630200 Zimmermann, 2004, Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase, Science, 306, 1383, 10.1126/science.1100747