Physicians' attitudes toward clinical trials and their relationship to patient accrual in a nordic multicenter study on myeloma

Controlled Clinical Trials - Tập 17 - Trang 372-386 - 1996
Martin Hjorth1, Erik Holmberg2, Stig Rödjer3, Adam Taube4, Jan Westin5
1Department of Medicine, Lidköping Hospital, Sweden
2Oncology Center, Sahlgrenska University Hospital, Sweden
3Department of Medicine, Östra University Hospital, Göteborg, Sweden
4Department of Statistics, Uppsala University, Sweden
5Department of Medicine, Lund University Hospital, Sweden

Tài liệu tham khảo

Hunninghake, 1987, Recruitment experience in clinical trials: Literature summary and annotated bibliography, Control Clin Trials, 8, 6S, 10.1016/0197-2456(87)90004-3 Friedman, 1990, National Cancer Institute Sponsored Cooperative Clinical Trials, Cancer, 65, 2376, 10.1002/1097-0142(19900515)65:10+<2376::AID-CNCR2820651504>3.0.CO;2-A 1991, Viability of cancer clinical research: patient accrual, coverage, and reimbursement, JNCI, 83, 254, 10.1093/jnci/83.4.254 Johansen, 1991, Obstacles in implementing cancer clinical trials, 7, 260 Martin, 1984, Accrual of patients into a multihospital cancer clinical trial and its implications on planning future studies, Am J Clin Oncol., 7, 173, 10.1097/00000421-198404000-00011 Taylor, 1994, Fundamental dilemmas of the randomized clinical trial process: results of a survey of the 1,737 Eastern Cooperative Oncology Group investigators, J Clin Oncol., 12, 1796, 10.1200/JCO.1994.12.9.1796 Hunter, 1987, Selection factors in clinical trials: Results from the Community Clinical Oncology Program physician's patient log, Cancer Treat Rep., 71, 559 Fisher, 1991, Clinical trials in cancer therapy: efforts to improve patient enrollment by community oncologists, Med Pediatr Oncol, 19, 165, 10.1002/mpo.2950190304 Cassileth, 1982, Attitudes toward clinical trials among patients and the public, JAMA, 248, 968, 10.1001/jama.1982.03330080050028 1996, Interferon-alfa-2b added to melphalan-prednisone for initial and maintenance treatment in multiple myeloma: a randomized, controlled trial, Ann Intern Med., 124, 212, 10.7326/0003-4819-124-2-199601150-00004 Hjorth, 1995, Patient accrual and quality of participation in a multicenter study on myeloma—a comparison between major and minor participating centers, Br J Haematol., 91, 109, 10.1111/j.1365-2141.1995.tb05254.x Hjorth, 1992, Impact of active and passive exclusions on the results of a clinical trial in multiple myeloma, Br J Haematol., 80, 55, 10.1111/j.1365-2141.1992.tb06400.x Benson, 1991, Oncologists' reluctance to accrue patients onto clinical trials: an Illinois Cancer Center Study, J Clin Oncol., 9, 2067, 10.1200/JCO.1991.9.11.2067 Taylor, 1984, Physicians' reasons for not entering eligible patients in a randomized clinical trial of surgery for breast cancer, N Engl J Med., 310, 1363, 10.1056/NEJM198405243102106 Taylor, 1987, Interpreting physician participation in randomized clinical trials: the Physician Orientation Profile, J Health Soc Behav., 28, 389, 10.2307/2136792 Pocock, 1983 Shuster, 1985, Ethical issues in cooperative cancer therapy trials from a statistical viewpoint. I. A general overview, Am J Pediatr Hematol/Oncol., 7, 57 Zelen, 1979, A new design for randomized clinical trials, N Engl J Med., 300, 1242, 10.1056/NEJM197905313002203 Schafer, 1982, The ethics of the randomized clinical trial, N Engl J Med., 307, 719, 10.1056/NEJM198209163071204 Farrar, 1991, Clinical trials. Access and reimbursement, Cancer, 67, 1779, 10.1002/cncr.2820671815