Physical activity and estrogen treatment reduce visceral body fat and serum levels of leptin in an additive manner in a diet induced animal model of obesity

The Journal of Steroid Biochemistry and Molecular Biology - Tập 122 Số 1-3 - Trang 100-105 - 2010
Nora Zoth1, Carmen Weigt1, Ute Laudenbach‐Leschowski1, Patrick Diel1
1Department of Cellular and Molecular Sports Medicine, Institute of Cardiovascular Research and Sports Medicine, German Sports University, Cologne, Germany.

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Wilson, 1999, Clustering of metabolic factors and coronary heart disease, Arch. Intern. Med., 159, 1104, 10.1001/archinte.159.10.1104

Park, 2003, The metabolic syndrome, Arch. Intern. Med., 163, 427, 10.1001/archinte.163.4.427

Janka, 2002, Epidemiology of diabetes mellitus: prevalence, incidence, pathogenesis and prognosis, Z. Arztl. Fortbild. Qualitätssich, 96, 159

Rosi, 2008, Metabolic syndrome affects cardiovascular risk profile and response to treatment in hypertensive postmenopausal women, Hypertension, 52, 865, 10.1161/HYPERTENSIONAHA.108.110478

Pasquali, 2008, Steroids and the metabolic syndrome, J. Steroid Biochem. Mol. Biol., 109, 258, 10.1016/j.jsbmb.2008.03.009

Saad, 2009, The role of testosterone in the metabolic syndrome: A review, J. Steroid Biochem. Mol. Biol., 114, 40, 10.1016/j.jsbmb.2008.12.022

Yanase, 2008, Androgens and metabolic syndrome: lessons from androgen receptor knock out (ARKO) mice, J. Steroid Biochem. Mol. Biol., 109, 254, 10.1016/j.jsbmb.2008.03.017

Simpson, 2005, a fundamental player in energy homeostasis, J. Steroid Biochem. Mol. Biol., 95, 3, 10.1016/j.jsbmb.2005.04.018

Toth, 2000, Menopause-related changes in body fat distribution, Ann. N. Y. Acad. Sci., 904, 502, 10.1111/j.1749-6632.2000.tb06506.x

Jones, 2007, Estrogen and adiposity–Utilizing models of aromatase deficiency to explore the relationship, J. Steroid Biochem. Mol. Biol., 106, 3, 10.1016/j.jsbmb.2007.05.029

Richard, 1987, Effects of exercise training on energy balance of ovariectomized rats, Am. J. Physiol. Regul. Integr. Comp. Physiol., 253, R740, 10.1152/ajpregu.1987.253.5.R740

Hertrampf, 2007, The bone-protective effect of the phytoestrogen genistein is mediated via ER alpha-dependent mechanisms and strogly enhanced by physical activity, Bone, 40, 1529, 10.1016/j.bone.2007.02.006

Bailey, 1980, Role of ovarian hormones in the long-term control of glucose homeostasis, Diabetologia, 19, 475, 10.1007/BF00281829

Beral, 2003, Breast cancer and hormone-replacement therapy in the Million Women Study, Lancet, 362, 419, 10.1016/S0140-6736(03)14596-5

James, 1984, Effect of exercise training on whole-body insulin sensitivity and responsiveness, J. Appl. Physiol., 56, 1217, 10.1152/jappl.1984.56.5.1217

Saengsirisuwan, 2008, Modulation of insulin resistance in ovariectomized rats by endurance exercise training and estrogen replacement, Metabolism, 58, 38, 10.1016/j.metabol.2008.08.004

Latour, 2001, Metabolic effects of physical training in ovariectomized and hyperestrogenic rats, J. Appl. Physiol., 90, 235, 10.1152/jappl.2001.90.1.235

Matthews, 1985, Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man, Diabetologia, 28, 412, 10.1007/BF00280883

Campbell, 2001, Effects of ovarian hormones on exercise metabolism, Curr. Opin. Clin. Nutr. Metab. Care, 4, 515, 10.1097/00075197-200111000-00009

Haram, 2009, Aerobic interval training vs. continuous moderate exercise in the metabolic syndrome of rats artificially selected for low aerobic capacity, Cardiovasc. Res., 81, 723, 10.1093/cvr/cvn332

Diel, 2005, Pulsed estradiol exposure has a limited ability to induce uterine proliferation in ovariectomized female Wistar rats, J. Mol. Cell Endocrinol., 230, 7, 10.1016/j.mce.2004.11.007

Hertrampf, 2006, Combined effects of physical activity, dietary isoflavones and 17beta-estradiol on movement drive, body weight and bone mineral density in ovariectomized female rats, Planta Med., 72, 484, 10.1055/s-2006-931579

Schleipen, 2008, Estrogen receptor subtype-specific effects on markers of bone homeostasis, Mol. Cell Endocrinol., 291, 104, 10.1016/j.mce.2008.03.003

Dohm, 1981, The ovariectomized female rat as a model animal for the study of adaptation to endurance training, Lab Anim. Sci., 31, 146

Mazzeo, 1986, Effects of training on weight, food intake, and body composition in aging rats, Am. J. Clin. Nutr., 44, 732, 10.1093/ajcn/44.6.732

Picard, 2000, Effects of the estrogen antagonist EM-652.HCI on energy balance and lipid metabolism in ovariectomized rats, Int. J. Obes., 24, 830, 10.1038/sj.ijo.0801240

Gray, 1981, Food intake, body weight, and adiposity in female rats: actions and interactions of progestins and antiestrogens, Am. J. Physiol. (Endocrinol. Metab.), 240, E474, 10.1152/ajpendo.1981.240.5.E474

Shinoda, 2002, Effects of physical training on body composition and organ weights in ovariectomized and hyperestrogenic rats, Int. J. Obes., 26, 335, 10.1038/sj.ijo.0801900

Zhang, 1994, Positional cloning of the mouse obese gene and its human homologue, Nature, 372, 425, 10.1038/372425a0

Friedman, 1998, Leptin and the regulation of body weight in mammals, Nature, 395, 763, 10.1038/27376

Hashimi, 2000, Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesitiy, J. Clin. Invest., 105, 1827, 10.1172/JCI9842

Wade, 2004, Regulation of body fat content?, Am. J. Physiol. Regul. Integr. Comp. Physiol., 286, R14, 10.1152/ajpregu.00583.2003

Stevenson, 2000, Cardiovascular effects of oestrogens, J. Steroid. Biochem. Mol. Biol., 74, 387, 10.1016/S0960-0760(00)00117-5

Mestek, 2009, Physical activity, blood lipids and lipoproteins, Am. J. Lifestyle Med., 3, 279, 10.1177/1559827609334885