Phthalates: European regulation, chemistry, pharmacokinetic and related toxicity
Tóm tắt
Từ khóa
Tài liệu tham khảo
Abbott, 2009, Review of the expression of peroxisome proliferator-activated receptors alpha (PPAR alpha), beta (PPAR beta), and gamma (PPAR gamma) in rodent and human development, Reprod. Toxicol., 27, 246, 10.1016/j.reprotox.2008.10.001
Akingbemi, 2001, Oestrogenic and antiandrogenic chemicals in the environment: effects on male reproductive health, Ann. Med., 33, 391, 10.3109/07853890108995952
Andrade, 2006, A dose response study following in utero and lactational exposure to di-(2-ethylheyl) phatalate (DEHP): effects on androgenic status, developmental landmarks and testicular histology in male offspring rats, Toxicology, 225, 64, 10.1016/j.tox.2006.05.007
Anney, 2011, Gene-ontology enrichment analysis in two independent family-based samples highlights biologically plausible processes for autism spectrum disorders, Eur. J. Hum. Genet., 19, 1082, 10.1038/ejhg.2011.75
ATSDR (Agency for Toxic Substances and Disease Registry), 2002
Becker, 2004, DEHP metabolites in urine of children and DEHP in house dust, Int. J. Hyg. Environ. Health, 207, 409, 10.1078/1438-4639-00309
Bility, 2004, Activation of mouse and human peroxisome proliferator-activated receptors (PPARs) by phthalate monoesters, Toxicol. Sci., 82, 170, 10.1093/toxsci/kfh253
Bornehag, 2010, Phthalate exposure and asthma in children, Int. J. Androl., 33, 333, 10.1111/j.1365-2605.2009.01023.x
Braissant, 1996, Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-α, -β, and -γ in the adult rat, Endocrinology, 137, 354, 10.1210/en.137.1.354
Calafat, 2006, Human exposure assessment to environmental chemicals using biomonitoring, Int. J. Androl., 29, 166, 10.1111/j.1365-2605.2005.00570.x
Calley, 1966, Toxicology of a series of phthalate esters, J. Pharm. Sci., 55, 158, 10.1002/jps.2600550206
Canada Gazette, Vol. 144, No. 26 – December 22, 2010. http://gazette.gc.ca/rp-/p2/2010/2010-12-22/html/sor-dors298-eng.html.
Carbone, S., Ponzo, O.J., Gobetto, N., Samaniego, Y.A., Reynoso, R., Scacchi, P., Moguilevsky, J.A., Cutrera, R. Antiandrogenic effect of perinatal exposure to the endocrine disruptor di-(2-ethylhexyl) phthalate increases anxiety-like behavior in male rats during sexual maturation. Horm. Behav., in press.
Carbone, 2012, Different effects by sex on hypothalamic-pituitary axis of prepubertal offspring rats produced by in utero and lactational exposure to di-(2-ethylhexyl) phthalate (DEHP), Neurotoxicology, 33, 78, 10.1016/j.neuro.2011.11.009
Carbone, 2010, Impact of gestational and lactational phthalate exposure on hypothalamic content of amino acid neurotransmitters and FSH secretion in peripubertal male rats, Neurotoxicology, 31, 747, 10.1016/j.neuro.2010.06.006
Chen, 2012, Mono-2-ethylhexyl phthalate induced loss of mitochondrial membrane potential and activation of Caspase3 in HepG2 cells, Environ. Toxicol. Pharmacol., 33, 421, 10.1016/j.etap.2012.02.001
Chronic Hazard Advisory Panel, 1985
Colón, 2000, Identification of phthalate esters in the serum of young Puerto Rican girls with premature breast development, Environ. Health Perspect., 108, 895, 10.1289/ehp.00108895
Dalsenter, 2006, Phthalate affect the reproductive function and sexual behavior of male Wistar rats, Hum. Exp. Toxicol., 25, 297, 10.1191/0960327105ht624oa
David, 2004, Commentary regarding the article by Koch et al.: an estimation of the daily intake of di(2-ethylhexyl) phthalate (DEHP) and other phthalates in the general population, Int. J. Hyg. Environ. Health, 207, 75, 10.1078/1438-4639-00271
De Coster, 2012, Endocrine-disrupting chemicals: associated disorders and mechanisms of action, J. Environ. Public Health, 10.1155/2012/713696
European Food Safety Authority, 2005, Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC) on a request from the Commission related to butylbenzylphthalate (BBP) for use in food contact materials, EFSA J., 241, 1
Feige, 2007, The endocrine disruptor monoethyl-hexyl-phthalate is a selective peroxisome proliferator-activated receptor gamma modulator that promotes adipogenesis, J. Biol. Chem., 282, 19152, 10.1074/jbc.M702724200
Feleder, 1996, The GABAergic control of gonadotropin-realising hormone secretion in male rats during sexual maturation involves effects on hypothalamic excitatory and inhibitory amino acids systems, Neuroendocrinology, 64, 305, 10.1159/000127133
Foster, 1980, Study of the testicular effects and changes in zinc excretion produced by some n-alkyl phthalates in the rat, Toxicol. Appl. Pharmacol., 54, 392, 10.1016/0041-008X(80)90165-9
Grande, 2007, A dose–response study following in utero and lactational exposure to di-(2-ethylhexyl) phthalate (DEHP): reproductive effects on adult female offspring rats, Toxicology, 229, 114, 10.1016/j.tox.2006.10.005
Heindel, 1989, Reproductive toxicity of three phthalic acid esters in a continuous breeding protocol, Fundam. Appl. Toxicol., 12, 508, 10.1016/0272-0590(89)90024-9
Hu, 2009, Phthalate-induced testicular dysgenesis syndrome: Leydig cell influence, Trends. Endocrinol. Metab., 20, 139, 10.1016/j.tem.2008.12.001
Hurst, 2003, Activation of PPARα and PPARγ by environmental phthalate monoesters, Toxicol. Sci., 74, 297, 10.1093/toxsci/kfg145
Ito, 2007, Di(2-ethylhexyl)phthalate induces hepatic tumorigenesis through a peroxisome proliferator-activated receptor alpha-independent pathway, J. Occup. Health, 49, 172, 10.1539/joh.49.172
Jaakkola, 2008, The role of exposure to phthalates from polyvinyl chloride products in the development of asthma and allergies: a systematic review and meta-analysis, Environ. Health Perspect., 116, 845, 10.1289/ehp.10846
Jaakkola, 1999, Interior surface materials in the home and the development of bronchial obstruction in young children in Oslo, Norway, Am. J. Public Health., 89, 188, 10.2105/AJPH.89.2.188
Johnson, 2012, Of mice and men (and rats): phthalate-induced fetal testis endocrine disruption is species-dependent, Toxicol. Sci., 129, 235, 10.1093/toxsci/kfs206
Kamrin, 2009, Phthalate risks, phthalate regulation, and public health: a review, J. Toxicol. Environ. Health B: Crit. Rev., 12, 157, 10.1080/10937400902729226
Karel, 1947, The intraperitoneal toxicity of some glycols, glycol ethers, glycol esters, and phthalates in mice, J. Pharmacol. Exp. Ther., 90, 338
Kim, 2007, Di(2-ethylhexyl)phthalate leached from medical PVC devices serves as a substrate and inhibitor for the P-glycoprotein, Environ. Toxicol. Pharmacol., 23, 272, 10.1016/j.etap.2006.11.001
Kimber, 2010, An assessment of the ability of phthalates to influence immune and allergic responses, Toxicology, 271, 73, 10.1016/j.tox.2010.03.020
Klaunig, 2003, PPAR alpha agonist-induced rodent tumors: modes of action and human relevance, Crit. Rev. Toxicol., 33, 655, 10.1080/713608372
Koch, 2004, Di(2-ethylhexyl) phthalate (DEHP) metabolites in human urine and serum after a single oral dose of deuterium labelled DEHP, Arch. Toxicol., 78, 123, 10.1007/s00204-003-0522-3
Koch, 2003, Internal exposure of the general population to DEHP and other phthalates – determination of secondary and primary phthalate monoester metabolites in urine, Environ. Res., 93, 177, 10.1016/S0013-9351(03)00083-5
Komar, 2001, Expression and localization of PPARs in the rat ovary during follicular development and the periovulatory period, Endocrinology, 142, 4831, 10.1210/en.142.11.4831
Kruger, 2008, Plastic components affect the activation of the aryl hydrocarbon and the androgen receptor, Toxicology, 246, 112, 10.1016/j.tox.2007.12.028
Lapinskas, 2005, Role of PPARα in mediating the effects of phthalates and metabolites in the liver, Toxicology, 207, 149, 10.1016/j.tox.2004.09.008
Latini, 2003, In utero exposure to di-(2-ethylhexyl) phthalate and duration of human pregnancy, Environ. Health Perspect., 111, 1783, 10.1289/ehp.6202
Li, 2013, Dose-related effect by maternal exposure to di-(2-ethylhexyl) phthalate plasticizer on inducing hypospadiac male rats, Environ. Toxicol. Pharmacol., 35, 55, 10.1016/j.etap.2012.10.006
Li, 2012, Di-(2-ethylhcxyl) phthalate reduces progesterone levels and induces apoptosis of ovarian granulosa cell in adult female ICR mice, Environ. Toxicol. Pharmacol., 34, 869, 10.1016/j.etap.2012.08.013
Liu, 1986, Synergism between granulosa and theca-interstitial cells in estrogen biosynthesis by gonadotropin-treated rat ovaries: studies on the two-cell, two-gonadotropin hypothesis using steroid antisera, Biol. Reprod., 35, 27, 10.1095/biolreprod35.1.27
Lopez-Carrillo, 2010, Exposure to phthalates and breast cancer risk in northern Mexico, Environ. Health Perspect., 118, 539, 10.1289/ehp.0901091
Lovekamp-Swan, 2003, Mechanisms of phthalate ester toxicity in the female reproductive system, Environ. Health Perspect., 111, 139, 10.1289/ehp.5658
Lovekamp, 2001, Mono-(2-ethylhexyl) phthalate suppresses aromatase transcript levels and estradiol production in cultured rat garnulosa cells, Toxicol. Appl. Pharmacol., 172, 217, 10.1006/taap.2001.9156
Maloney, 1999, Trans-activation of PPARα and PPARγ by structurally diverse environmental chemicals, Toxicol. Appl. Pharmacol., 161, 209, 10.1006/taap.1999.8809
Mu, 2000, Insulin sensitizer, troglitazone, directly inhibits aromatase activity in human ovarian granulosa cells, Biochem. Biophys. Res. Commun., 271, 710, 10.1006/bbrc.2000.2701
Murphy, 2010, Recent advances in the pathophysiology of asthma, Chest, 137, 1417, 10.1378/chest.09-1895
Nelson, 1991, Prenatal and perinatal factors in the etiology of autism, Pediatrics, 87, 761, 10.1542/peds.87.5.761
Pelaia, 2008, Molecular mechanisms underlying airway smooth muscle contraction and proliferation: implications for asthma, Respir. Med., 102, 1173, 10.1016/j.rmed.2008.02.020
Pelaia, 2009, Biological targets for therapeutic interventions in COPD: clinical potential, Int. J. Chron. Obstruct. Pulmon. Dis., 1, 321
Preuss, 2005, Biological monitoring of the five major metabolites of di-(2-ethylhexyl)phthalate (DEHP) in human urine using column-switching liquid chromatography-tandem mass spectrometry, J. Chromatogr., 816, 269
Rusyn, 2006, Modes of action and species-specific effects of di-(2-ethylhexyl)phthalate in the liver, Toxicology, 36, 459
Sampson, 2011, DEHP-plasticised PVC: relevance to blood services, Transfus. Med., 21, 73, 10.1111/j.1365-3148.2010.01056.x
Schlezinger, 2006, A role for the aryl hydrocarbon receptor in mammary gland tumorigenesis, Biol. Chem., 387, 1175, 10.1515/BC.2006.145
Schmid, 1985, Excretion and metabolism of di(2-ethylhexyl)phthalate in man, Xenobiotica, 15, 251, 10.3109/00498258509045356
Selenskas, 1995, Pancreatic cancer among workers processing synthetic resins, Am. J. Ind. Med., 28, 385, 10.1002/ajim.4700280308
Sjoberg, 1991, Glucuronidation of mono(2-ethylhexyl)phthalate. Some enzyme characteristics and inhibition by bilirubin, Biochem. Pharmacol., 41, 1493, 10.1016/0006-2952(91)90566-N
Skakkebaek, 2001, Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects, Hum. Reprod., 16, 972, 10.1093/humrep/16.5.972
Snijder, 2012, Occupational exposure to chemicals and fetal growth: the Generation R Study, Hum. Reprod., 27, 910, 10.1093/humrep/der437
Svechnikova, 2007, The influence of di-(2-ethylhexyl) phthalate on steroidogenesis by the ovarian granulose cells of immature female rats, J. Endocrinol., 194, 603, 10.1677/JOE-07-0238
Swan, 2008, Environmental phthalate exposure in relation to reproductive outcomes and other health endpoints in humans, Environ. Res., 108, 177, 10.1016/j.envres.2008.08.007
Testa, 2012, Di-(2-ethylhexyl) phthalate and autism spectrum disorders, ASN NEURO, 4, 223, 10.1042/AN20120015
Tomita, 1986, Fetotoxic effects of mono-2-ethylhexyl phthalate (MEHP) in mice, Environ. Health. Perspect., 65, 249
Treinen, 1990, Inhibition of FSH stimulated cAMP accumulation and progesterone production by mono(2-ethylhexyl) phthalate in rat granulosa cell cultures, Toxicol. Appl. Pharmacol., 106, 334, 10.1016/0041-008X(90)90252-P
Wittassek, 2008, Phthalates: metabolism and exposure, Int. J. Androl., 31, 131, 10.1111/j.1365-2605.2007.00837.x
Yang, 2008, The PPAR alpha-humanized mouse: a model to investigate species differences in liver toxicity mediated by PPAR alpha, Toxicol. Sci., 101, 132, 10.1093/toxsci/kfm206