Photochemical Perfluoroalkylation with Pyridine N -Oxides: Mechanistic Insights and Performance on a Kilogram Scale

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As previously noted, the reaction also becomes dark, thus further limiting light penetration.

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See the Supplemental Information for full details of the reactor design.

Pumps were temporarily stopped for <1 min while the feed bottles were refilled.

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We use 24 hr to define a day, but it should be appreciated that in many cases, other restrictions may prevent full 24 hr operation on a large (e.g., plant) manufacturing scale.

Many visible-light-mediated reactions have higher quantum yields, i.e., ≫1 where photon flux may not be the limiting factor. See Luo and Zhang.83