Phosphorylation-Dependent Protein Interactions at the Spindle Midzone Mediate Cell Cycle Regulation of Spindle Elongation

Developmental Cell - Tập 17 Số 2 - Trang 244-256 - 2009
Anton Khmelinskii1, Johanna Roostalu, Hélio Roque, Claude Antony, Elmar Schiebel
1Zentrum für Molekulare Biologie der Universität Heidelberg, DKFZ-ZMBH Allianz, Im Neuenheiemer Feld 282, Heidelberg 69117, Germany.

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Baskerville, 2008, The protease activity of yeast separase (esp1) is required for anaphase spindle elongation independently of its role in cleavage of cohesin, Genetics, 178, 2361, 10.1534/genetics.107.085308

Bratman, 2007, Stabilization of overlapping microtubules by fission yeast CLASP, Dev. Cell, 13, 812, 10.1016/j.devcel.2007.10.015

D'Aquino, 2005, The protein kinase Kin4 inhibits exit from mitosis in response to spindle position defects, Mol. Cell, 19, 223, 10.1016/j.molcel.2005.06.005

Fu, 2009, Phosphorylation-dependent anchoring of a kinesin-6 motor klp9p to the microtubule bundler ase1p is required for proper anaphase B, Dev. Cell, 17, 257, 10.1016/j.devcel.2009.06.012

Gardner, 2008, Chromosome congression by Kinesin-5 motor-mediated disassembly of longer kinetochore microtubules, Cell, 135, 894, 10.1016/j.cell.2008.09.046

Glotzer, 2009, The 3Ms of central spindle assembly: microtubules, motors and MAPs, Nat. Rev. Mol. Cell Biol., 10, 9, 10.1038/nrm2609

Goshima, 2000, Establishing biorientation occurs with precocious separation of the sister kinetochores, but not the arms, in the early spindle of budding yeast, Cell, 100, 619, 10.1016/S0092-8674(00)80699-6

Higuchi, 2005, Stabilization of microtubule dynamics at anaphase onset promotes chromosome segregation, Nature, 433, 171, 10.1038/nature03240

Hoog, 2007, Whole-cell investigation of microtubule cytoskeleton architecture by electron tomography, Methods Cell Biol., 79, 145, 10.1016/S0091-679X(06)79006-9

Hoyt, 1992, Two Saccharomyces cerevisiae kinesin-related gene products required for mitotic spindle assembly, J. Cell Biol., 118, 109, 10.1083/jcb.118.1.109

Janke, 2004, A versatile toolbox for PCR-based tagging of yeast genes: new fluorescent proteins, more markers and promoter substitution cassettes, Yeast, 21, 947, 10.1002/yea.1142

Janson, 2007, Crosslinkers and motors organize dynamic microtubules to form stable bipolar arrays in fission yeast, Cell, 128, 357, 10.1016/j.cell.2006.12.030

Jensen, 2001, A novel role of the budding yeast separin Esp1 in anaphase spindle elongation: evidence that proper spindle association of Esp1p is regulated by Pds1p, J. Cell Biol., 152, 27, 10.1083/jcb.152.1.27

Jiang, 1998, PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis, Mol. Cell, 2, 877, 10.1016/S1097-2765(00)80302-0

Jin, 2008, Temporal control of the dephosphorylation of Cdk substrates by mitotic exit pathways in budding yeast, Proc. Natl. Acad. Sci. USA, 105, 16177, 10.1073/pnas.0808719105

Juang, 1997, APC-mediated proteolysis of Ase1 and the morphogenesis of the mitotic spindle, Science, 275, 1311, 10.1126/science.275.5304.1311

Kapitein, 2005, The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks, Nature, 435, 114, 10.1038/nature03503

Kapitein, 2008, Microtubule-driven multimerization recruits ase1p onto overlapping microtubules, Curr. Biol., 18, 1713, 10.1016/j.cub.2008.09.046

Kapitein, 2008, Microtubule cross-linking triggers the directional motility of kinesin-5, J. Cell Biol., 182, 421, 10.1083/jcb.200801145

Kerssemakers, 2006, The distance that kinesin-1 holds its cargo from the microtubule surface measured by fluorescence interference contrast microscopy, Proc. Natl. Acad. Sci. USA, 103, 15812, 10.1073/pnas.0510400103

Khmelinskii, 2007, Cdc14-regulated midzone assembly controls anaphase B, J. Cell Biol., 177, 981, 10.1083/jcb.200702145

Kotwaliwale, 2007, A pathway containing the Ipl1/aurora protein kinase and the spindle midzone protein Ase1 regulates yeast spindle assembly, Dev. Cell, 13, 433, 10.1016/j.devcel.2007.07.003

Loog, 2005, Cyclin specificity in the phosphorylation of cyclin-dependent kinase substrates, Nature, 434, 104, 10.1038/nature03329

Maddox, 2000, The polarity and dynamics of microtubule assembly in the budding yeast Saccharomyces cerevisiae, Nat. Cell Biol., 2, 36, 10.1038/71357

Miller, 1998, The kinesin-related proteins, Kip2p and Kip3p, function differently in nuclear migration in yeast, Mol. Biol. Cell, 9, 2051, 10.1091/mbc.9.8.2051

Mishima, 2002, Central spindle assembly and cytokinesis require a kinesin-like protein/RhoGAP complex with microtubule bundling activity, Dev. Cell, 2, 41, 10.1016/S1534-5807(01)00110-1

Mishima, 2004, Cell cycle regulation of central spindle assembly, Nature, 430, 908, 10.1038/nature02767

Mollinari, 2002, PRC1 is a microtubule binding and bundling protein essential to maintain the mitotic spindle midzone, J. Cell Biol., 157, 1175, 10.1083/jcb.200111052

Neef, 2007, Choice of Plk1 docking partners during mitosis and cytokinesis is controlled by the activation state of Cdk1, Nat. Cell Biol., 9, 436, 10.1038/ncb1557

Pereira, 2003, Separase regulates INCENP-Aurora B anaphase spindle function through Cdc14, Science, 302, 2120, 10.1126/science.1091936

Queralt, 2006, Downregulation of PP2A(Cdc55) phosphatase by separase initiates mitotic exit in budding yeast, Cell, 125, 719, 10.1016/j.cell.2006.03.038

Rahal, 2008, Mitotic CDKs control the metaphase-anaphase transition and trigger spindle elongation, Genes Dev., 22, 1534, 10.1101/gad.1638308

Saunders, 1992, Kinesin-related proteins required for structural integrity of the mitotic spindle, Cell, 70, 451, 10.1016/0092-8674(92)90169-D

Saunders, 1995, Saccharomyces cerevisiae kinesin- and dynein-related proteins required for anaphase chromosome segregation, J. Cell Biol., 128, 617, 10.1083/jcb.128.4.617

Schuyler, 2003, The molecular function of Ase1p: evidence for a MAP-dependent midzone-specific spindle matrix, J. Cell Biol., 160, 517, 10.1083/jcb.200210021

Schwartz, 1997, BIM1 encodes a microtubule-binding protein in yeast, Mol. Biol. Cell, 8, 2677, 10.1091/mbc.8.12.2677

Severin, 2001, Correct spindle elongation at the metaphase/anaphase transition is an APC-dependent event in budding yeast, J. Cell Biol., 155, 711, 10.1083/jcb.200104096

Shirayama, 1999, APC-Cdc20 promotes exit from mitosis by destroying the anaphase inibitor Pds1 and cyclin Clb5, Nature, 402, 203, 10.1038/46080

Shou, 1999, Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex, Cell, 97, 233, 10.1016/S0092-8674(00)80733-3

Stegmeier, 2002, Separase, polo kinase, the kinetochore protein Slk19, and Spo12 function in a network that controls Cdc14 localization during early anaphase, Cell, 108, 207, 10.1016/S0092-8674(02)00618-9

Straight, 1997, Mitosis in living budding yeast: anaphase A but no metaphase plate, Science, 277, 574, 10.1126/science.277.5325.574

Straight, 1998, Time-lapse microscopy reveals unique roles for kinesins during anaphase in budding yeast, J. Cell Biol., 143, 687, 10.1083/jcb.143.3.687

Sullivan, 2007, Finishing mitosis, one step at a time, Nat. Rev. Mol. Cell Biol., 8, 894, 10.1038/nrm2276

Sullivan, 2003, A non-proteolytic function of separase links the onset of anaphase to mitotic exit, Nat. Cell Biol., 5, 249, 10.1038/ncb940

Sullivan, 2001, Orchestrating anaphase and mitotic exit: separase cleavage and localization of Slk19, Nat. Cell Biol., 3, 771, 10.1038/ncb0901-771

Tytell, 2006, Analysis of kinesin motor function at budding yeast kinetochores, J. Cell Biol., 172, 861, 10.1083/jcb.200509101

Ubersax, 2003, Targets of the cyclin-dependent kinase Cdk1, Nature, 425, 859, 10.1038/nature02062

Uhlmann, 2000, Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast, Cell, 103, 375, 10.1016/S0092-8674(00)00130-6

van den Wildenberg, 2008, The homotetrameric kinesin-5 KLP61F preferentially crosslinks microtubules into antiparallel orientations, Curr. Biol., 18, 1860, 10.1016/j.cub.2008.10.026

Visintin, 1997, CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis, Science, 278, 460, 10.1126/science.278.5337.460

Winey, 1995, Three-dimensional ultrastructural analysis of the Saccharomyces cerevisiae mitotic spindle, J. Cell Biol., 129, 1601, 10.1083/jcb.129.6.1601

Yeong, 2000, Exit from mitosis in budding yeast: biphasic inactivation of the Cdc28-Clb2 mitotic kinase and the role of Cdc20, Mol. Cell, 5, 501, 10.1016/S1097-2765(00)80444-X

Zhu, 2006, Spatiotemporal control of spindle midzone formation by PRC1 in human cells, Proc. Natl. Acad. Sci. USA, 103, 6196, 10.1073/pnas.0506926103