Phospholipase C/Protein Kinase C Pathway Mediates Angiotensin II-Dependent Apoptosis in Neonatal Rat Cardiac Fibroblasts Expressing AT1 Receptor

Booz, 1995, Molecular signalling mechanisms controlling growth and function of cardiac fibroblasts., Cardiovasc Res, 30, 537, 10.1016/S0008-6363(96)88507-5

de Gasparo, 2000, International union of pharmacology XXIII: The angiotensin II receptors., Pharmacol Rev, 52, 415

Clauser, 1996, Angiotensin II receptors: protein and gene structures, expression and potential pathological involvements., Eur J Endocrinol, 134, 403, 10.1530/eje.0.1340403

Gray, 1998, Angiotensin II stimulates cardiac myocyte hypertrophy via paracrine release of TGF-beta 1 and endothelin-1 from fibroblasts., Cardiovasc Res, 40, 352, 10.1016/S0008-6363(98)00121-7

Carey, 2005, Cardiovascular and renal regulation by the angiotensin type 2 receptor, the AT2 receptor comes of age., Hypertension, 45, 840, 10.1161/01.HYP.0000159192.93968.8f

Goldenberg, 2001, Angiotensin II-induced apoptosis in rat cardiomyocyte culture: a possible role of AT1 and AT2 receptors., J Hypertens, 19, 1681, 10.1097/00004872-200109000-00022

Sadoshima, 1993, Molecular characterization of angiotensin II-induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts: Critical role of the AT1 receptor subtype., Circ Res, 73, 413, 10.1161/01.RES.73.3.413

Mayorga, 2004, Bcl-2 is a key factor for cardiac fibroblast resistance to programmed cell death., J Biol Chem, 279, 34882, 10.1074/jbc.M404616200

Shinoura, 1999, Relative level of expression of Bax and Bcl-XL determines the cellular fate of apoptosis/necrosis induced by the overexpression of Bax., Oncogene, 18, 5703, 10.1038/sj.onc.1202966

Shinoura, 1999, Expression level of Bcl-2 determines anti- or proapoptotic function., Cancer Res, 59, 4119

Crow, 2004, The mitochondrial death pathway and cardiac myocyte apoptosis., Circ Res, 95, 957, 10.1161/01.RES.0000148632.35500.d9

Gallagher, 1998, Species variability in angiotensin receptor expression by cultured cardiac fibroblasts and the infarcted heart., Am J Physiol, 274, H801

Thaik, 1995, Interleukin-1 beta modulates the growth and phenotype of neonatal rat cardiac myocytes., J Clin Invest, 96, 1093, 10.1172/JCI118095

Claycomb, 1980, Culture of the terminally differentiated adult cardiac muscle cell: a light and scanning electron microscope study., Dev Biol, 80, 466, 10.1016/0012-1606(80)90419-4

Thomas, 2002, Adenoviral-directed expression of the type 1A angiotensin receptor promotes cardiomyocyte hypertrophy via transactivation of the epidermal growth factor receptor., Circ Res, 90, 135, 10.1161/hh0202.104109

Schorb, 1993, Angiotensin II is mitogenic in neonatal rat cardiac fibroblasts., Circ Res, 72, 1245, 10.1161/01.RES.72.6.1245

Crabos, 1994, Characterization of angiotensin II receptors in cultured adult rat cardiac fibroblasts. Coupling to signaling systems and gene expression., J Clin Invest, 93, 2372, 10.1172/JCI117243

Kawano, 2000, Angiotensin II has multiple profibrotic effects in human cardiac fibroblasts., Circulation, 101, 1130, 10.1161/01.CIR.101.10.1130

Lefroy, 1996, Regional changes in angiotensin II receptor density after experimental myocardial infarction., J Mol Cell Cardiol, 28, 429, 10.1006/jmcc.1996.0039

Meggs, 1993, Regulation of angiotensin II receptors on ventricular myocytes after myocardial infarction in rats., Circ Res, 72, 1149, 10.1161/01.RES.72.6.1149

Mackenna, 1996, Regulation of radiation-induced apoptosis in oncogene-transfected fibroblasts: influence of H-ras on the G2 delay., Oncogene, 12, 237

McGill, 1997, Loss of matrix adhesion triggers rapid transformation-selective apoptosis in fibroblasts., J Cell Biol, 138, 901, 10.1083/jcb.138.4.901

Yamada, 1996, Angiotensin II type 2 receptor mediates programmed cell death., Proc Natl Acad Sci, 93, 156, 10.1073/pnas.93.1.156

Bascands, 2001, Angiotensin II induces phenotype-dependent apoptosis in vascular smooth muscle cells., Hypertension, 38, 1294, 10.1161/hy1201.096540

Li, 1999, Proapoptotic effects of Ang II in human coronary artery endothelial cells: role of AT1 receptor and PKC activation., Am J Physiol, 276, H786

Bouzegrhane, 2002, Is angiotensin II a proliferative factor of cardiac fibroblasts., Cardiovasc Res, 53, 304, 10.1016/S0008-6363(01)00448-5

Braun, 2003, Opposing effects of delta and zeta protein kinase C isozymes on cardiac fibroblast proliferation: use of isozyme-selective inhibitors., J Mol Cel Cardiol, 35, 895, 10.1016/S0022-2828(03)00142-1

Gogvadze, 2001, Cytochrome c release occurs via Ca2+-dependent and Ca2+-independent mechanisms that are regulated by Bax., J Biol Chem, 276, 19066, 10.1074/jbc.M100614200

Zou, 1998, Cell type-specific angiotensin II-evoked signal transduction pathways: critical roles of G subunit, Src family, and Ras in cardiac fibroblasts., Circ Res, 82, 337, 10.1161/01.RES.82.3.337

Colombo, 2001, Beta-Adrenergic stimulation of rat cardiac fibroblasts promotes protein synthesis via the activation of phosphatidylinositol 3-kinase., J Mol Cell Cardiol, 33, 1091, 10.1006/jmcc.2001.1381

Piacentini, 2000, Endothelin-1 stimulates cardiac fibroblast proliferation through activation of protein kinase., J Mol Cell Cardiol, 32, 565, 10.1006/jmcc.2000.1109

Kapoun, 2004, B-type natriuretic peptide exerts broad functional opposition to transforming growth factor-ss in primary human cardiac fibroblasts., Circ Res, 94, 453, 10.1161/01.RES.0000117070.86556.9F

Tian, 2002, Mechanisms of cytokine induced NO-mediated cardiac fibrolast apoptosis., Am J Physiol Heart Circ Physiol, 283, H1958, 10.1152/ajpheart.01070.2001