Phosphate Sensing
Tóm tắt
Từ khóa
Tài liệu tham khảo
Bevington, 1992, Phosphate-sensitive enzymes: possible molecular basis for cellular disorders of phosphate metabolism, Clin Chem Enzyme Commun, 4, 235
Bevington, 1986, A study of intracellular orthophosphate concentration in human muscle and erythrocytes by 31P nuclear magnetic resonance spectroscopy and selective chemical assay, Clin Sci (Lond), 71, 729, 10.1042/cs0710729
Bun-Ya, 1991, The PHO84 gene of Saccharomyces cerevisiae encodes an inorganic phosphate transporter, Mol Cell Biol, 11, 3229, 10.1128/MCB.11.6.3229
Murer, 2004, The sodium phosphate cotransporter family SLC34, Pflugers Arch, 447, 763, 10.1007/s00424-003-1072-5
Wohlrab, 1986, Molecular aspects of inorganic phosphate transport in mitochondria, Biochim Biophys Acta, 853, 115, 10.1016/0304-4173(86)90007-8
Ferreira, 1993, Phosphate transport in mitochondria: past accomplishments, present problems, and future challenges, J Bioenerg Biomembr, 25, 483, 10.1007/BF01108405
Pisoni, 1992, Incorporation of [32P]orthophosphate into long chains of inorganic polyphosphate within lysosomes of human fibroblasts, J Biol Chem, 267, 3626, 10.1016/S0021-9258(19)50570-1
Pisoni, 1991, Characterization of a phosphate transport system in human fibroblast lysosomes, J Biol Chem, 266, 979, 10.1016/S0021-9258(17)35270-5
Bringhurst, 2006, Regulation of calcium and phosphate homeostasis, 805
Razzaque, 2009, Does FGF23 toxicity influence the outcome of chronic kidney disease?, Nephrol Dial Transplant, 24, 4, 10.1093/ndt/gfn620
Gutierrez, 2008, Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis, N Engl J Med, 359, 584, 10.1056/NEJMoa0706130
Mizobuchi, 2009, Vascular calcification: the killer of patients with chronic kidney disease, J Am Soc Nephrol, 20, 1453, 10.1681/ASN.2008070692
Stubbs, 2007, Role of hyperphosphatemia and 1,25-dihydroxyvitamin D in vascular calcification and mortality in fibroblastic growth factor 23 null mice, J Am Soc Nephrol, 18, 2116, 10.1681/ASN.2006121385
Morishita, 2001, The progression of aging in klotho mutant mice can be modified by dietary phosphorus and zinc, J Nutr, 131, 3182, 10.1093/jn/131.12.3182
Thevelein, 2005, Nutrient sensing systems for rapid activation of the protein kinase A pathway in yeast, Biochem Soc Trans, 33, 253, 10.1042/BST0330253
Brown, 1993, Cloning and characterization of an extracellular Ca2+-sensing receptor from bovine parathyroid, Nature, 366, 575, 10.1038/366575a0
Brown, 1994, A mammalian protein targeted by G1-arresting rapamycin-receptor complex, Nature, 369, 756, 10.1038/369756a0
MacDonald, 2005, Glucose-sensing mechanisms in pancreatic beta-cells, Philos Trans R Soc Lond B Biol Sci, 360, 2211, 10.1098/rstb.2005.1762
Hsieh, 2010, Global regulation by the seven-component Pi signaling system, Curr Opin Microbiol, 13, 198, 10.1016/j.mib.2010.01.014
Lamarche, 2008, The phosphate regulon and bacterial virulence: a regulatory network connecting phosphate homeostasis and pathogenesis, FEMS Microbiol Rev, 32, 461, 10.1111/j.1574-6976.2008.00101.x
Zundel, 1998, Analysis of the conserved acidic residues in the regulatory domain of PhoB, FEBS Lett, 441, 242, 10.1016/S0014-5793(98)01556-7
VanBogelen, 1996, Global analysis of proteins synthesized during phosphorus restriction in Escherichia coli, J Bacteriol, 178, 4344, 10.1128/jb.178.15.4344-4366.1996
Yuan, 2006, Genome prediction of PhoB regulated promoters in Sinorhizobium meliloti and twelve proteobacteria, Nucleic Acids Res, 34, 2686, 10.1093/nar/gkl365
Beard, 2000, Evidence for the transport of zinc(II) ions via the pit inorganic phosphate transport system in Escherichia coli, FEMS Microbiol Lett, 184, 231, 10.1111/j.1574-6968.2000.tb09019.x
Morales, 2006, Serendipitous discovery and X-ray structure of a human phosphate binding apolipoprotein, Structure, 14, 601, 10.1016/j.str.2005.12.012
Berna, 2009, The DING family of proteins: ubiquitous in eukaryotes, but where are the genes?, Bioessays, 31, 570, 10.1002/bies.200800174
Mouillon, 2006, New aspects on phosphate sensing and signalling in Saccharomyces cerevisiae, FEMS Yeast Res, 6, 171, 10.1111/j.1567-1364.2006.00036.x
Persson, 2003, Regulation of phosphate acquisition in Saccharomyces cerevisiae, Curr Genet, 43, 225, 10.1007/s00294-003-0400-9
Toh-e, 1988, PHO85, a negative regulator of the PHO system, is a homolog of the protein kinase gene, CDC28, of Saccharomyces cerevisiae, Mol Gen Genet, 214, 162, 10.1007/BF00340196
Oshima, 1997, The phosphatase system in Saccharomyces cerevisiae, Genes Genet Syst, 72, 323, 10.1266/ggs.72.323
Kaffman, 1994, Phosphorylation of the transcription factor PHO4 by a cyclin-CDK complex, PHO80-PHO85, Science, 263, 1153, 10.1126/science.8108735
Lenburg, 1996, Signaling phosphate starvation, Trends Biochem Sci, 21, 383, 10.1016/0968-0004(96)10048-7
Fristedt, 1996, Isolation and characterization of membrane vesicles of Saccharomyces cerevisiae harboring the high-affinity phosphate transporter, Arch Biochem Biophys, 330, 133, 10.1006/abbi.1996.0235
Auesukaree, 2004, Intracellular phosphate serves as a signal for the regulation of the PHO pathway in Saccharomyces cerevisiae, J Biol Chem, 279, 17289, 10.1074/jbc.M312202200
Lagerstedt, 2004, Structural modeling of dual-affinity purified Pho84 phosphate transporter, FEBS Lett, 578, 262, 10.1016/j.febslet.2004.11.012
Pratt, 2004, Effects of methylphosphonate, a phosphate analogue, on the expression and degradation of the high-affinity phosphate transporter Pho84, in Saccharomyces cerevisiae, Biochemistry, 43, 14444, 10.1021/bi049327t
Mouillon, 2005, Inhibition of the protein kinase A alters the degradation of the high-affinity phosphate transporter Pho84 in Saccharomyces cerevisiae, Curr Genet, 48, 226, 10.1007/s00294-005-0019-0
Huang, 2007, Structure of the Pho85-Pho80 CDK-cyclin complex of the phosphate-responsive signal transduction pathway, Mol Cell, 28, 614, 10.1016/j.molcel.2007.09.013
Huang, 2001, Functional analysis of the cyclin-dependent kinase inhibitor Pho81 identifies a novel inhibitory domain, Mol Cell Biol, 21, 6695, 10.1128/MCB.21.19.6695-6705.2001
Lee, 2007, Regulation of a cyclin-CDK-CDK inhibitor complex by inositol pyrophosphates, Science, 316, 109, 10.1126/science.1139080
Lee, 2008, Molecular basis of cyclin-CDK-CKI regulation by reversible binding of an inositol pyrophosphate, Nat Chem Biol, 4, 25, 10.1038/nchembio.2007.52
Swinnen, 2005, The minimum domain of Pho81 is not sufficient to control the Pho85-Rim15 effector branch involved in phosphate starvation-induced stress responses, Curr Genet, 48, 18, 10.1007/s00294-005-0583-3
Swinnen, 2006, Rim15 and the crossroads of nutrient signalling pathways in Saccharomyces cerevisiae, Cell Div, 1, 3, 10.1186/1747-1028-1-3
Petersson, 1999, Intracellular localization of an active green fluorescent protein-tagged Pho84 phosphate permease in Saccharomyces cerevisiae, FEBS Lett, 462, 37, 10.1016/S0014-5793(99)01471-4
Werner, 2001, Evolution of the Na-P(i) cotransport systems, Am J Physiol Regul Integr Comp Physiol, 280, R301, 10.1152/ajpregu.2001.280.2.R301
Kido, 1999, Identification of regulatory sequences and binding proteins in the type II sodium/phosphate cotransporter NPT2 gene responsive to dietary phosphate, J Biol Chem, 274, 28256, 10.1074/jbc.274.40.28256
Kornberg, 1999, Inorganic polyphosphate: a molecule of many functions, Annu Rev Biochem, 68, 89, 10.1146/annurev.biochem.68.1.89
Brown, 2004, Inorganic polyphosphate in the origin and survival of species, Proc Natl Acad Sci USA, 101, 16085, 10.1073/pnas.0406909101
Kato, 1993, Cloning, sequence and characterization of the polyphosphate kinase-encoding gene (ppk) of Klebsiella aerogenes, Gene, 137, 237, 10.1016/0378-1119(93)90013-S
Ghorbel, 2006, Transcriptional studies and regulatory interactions between the phoR-phoP operon and the phoU, mtpA, and ppk genes of Streptomyces lividans TK24, J Bacteriol, 188, 677, 10.1128/JB.188.2.677-686.2006
Rao, 1999, Inorganic polyphosphate regulates responses of Escherichia coli to nutritional stringencies, environmental stresses and survival in the stationary phase, Prog Mol Subcell Biol, 23, 183, 10.1007/978-3-642-58444-2_9
1979
Kulaev, 1983, Polyphosphate metabolism in micro-organisms, Adv Microb Physiol, 24, 83, 10.1016/S0065-2911(08)60385-9
Kulaev, 2000, Polyphosphate and phosphate pump, Annu Rev Microbiol, 54, 709, 10.1146/annurev.micro.54.1.709
Kulaev, 1999, New aspects of inorganic polyphosphate metabolism and function, J Biosci Bioeng, 88, 111, 10.1016/S1389-1723(99)80189-3
Thomas, 2005, An intracellular phosphate buffer filters transient fluctuations in extracellular phosphate levels, Proc Natl Acad Sci USA, 102, 9565, 10.1073/pnas.0501122102
Docampo, 2005, Acidocalcisomes - conserved from bacteria to man, Nat Rev Microbiol, 3, 251, 10.1038/nrmicro1097
Kumble, 1995, Inorganic polyphosphate in mammalian cells and tissues, J Biol Chem, 270, 5818, 10.1074/jbc.270.11.5818
Schmelzle, 2000, TOR, a central controller of cell growth, Cell, 103, 253, 10.1016/S0092-8674(00)00117-3
Tang, 2001, Amino acid-induced translation of TOP mRNAs is fully dependent on phosphatidylinositol 3-kinase-mediated signaling, is partially inhibited by rapamycin, and is independent of S6K1 and rpS6 phosphorylation, Mol Cell Biol, 21, 8671, 10.1128/MCB.21.24.8671-8683.2001
Jacinto, 2003, TOR signalling in bugs, brain and brawn, Nat Rev Mol Cell Biol, 4, 117, 10.1038/nrm1018
Martin, 2002, Coordinate regulation of translation by the PI 3-kinase and mTOR pathways, Adv Cancer Res, 86, 1, 10.1016/S0065-230X(02)86001-8
Shiba, 2003, Modulation of mitogenic activity of fibroblast growth factors by inorganic polyphosphate, J Biol Chem, 278, 26788, 10.1074/jbc.M303468200
Hernandez-Ruiz, 2006, Inorganic polyphosphate and specific induction of apoptosis in human plasma cells, Haematologica, 91, 1180
Beck, 2003, Inorganic phosphate as a signaling molecule in osteoblast differentiation, J Cell Biochem, 90, 234, 10.1002/jcb.10622
Schoeters, 1988, Mineralization of adult mouse bone marrow in vitro, Cell Tissue Kinet, 21, 363
Xie, 2004, Osteoblasts respond to hydroxyapatite surfaces with immediate changes in gene expression, J Biomed Mater Res A, 71, 108, 10.1002/jbm.a.30140
Quarles, 1992, Distinct proliferative and differentiated stages of murine MC3T3-E1 cells in culture: an in vitro model of osteoblast development, J Bone Miner Res, 7, 683, 10.1002/jbmr.5650070613
Otsuka, 1999, Characterization of osteoblastic differentiation of stromal cell line ST2 that is induced by ascorbic acid, Am J Physiol, 277, C132, 10.1152/ajpcell.1999.277.1.C132
Berendsen, 2010, Inorganic phosphate stimulates DMP1 expression in human periodontal ligament fibroblasts embedded in three-dimensional collagen gels, Cells Tissues Organs, 192, 116, 10.1159/000289585
Beck, 1998, Relationship between alkaline phosphatase levels, osteopontin expression, and mineralization in differentiating MC3T3-E1 osteoblasts, J Cell Biochem, 68, 269, 10.1002/(SICI)1097-4644(19980201)68:2<269::AID-JCB13>3.0.CO;2-A
Beck, 2000, Phosphate is a specific signal for induction of osteopontin gene expression, Proc Natl Acad Sci USA, 97, 8352, 10.1073/pnas.140021997
Yoshiko, 2007, Osteoblast autonomous Pi regulation via Pit1 plays a role in bone mineralization, Mol Cell Biol, 27, 4465, 10.1128/MCB.00104-07
Chang, 2006, Elevated inorganic phosphate stimulates Akt-ERK1/2-Mnk1 signaling in human lung cells, Am J Respir Cell Mol Biol, 35, 528, 10.1165/rcmb.2005-0477OC
Goseki-Sone, 2002, Phosphate depletion enhances bone morphogenetic protein-4 gene expression in a cultured mouse marrow stromal cell line ST2, Biochem Biophys Res Commun, 299, 395, 10.1016/S0006-291X(02)02646-3
Kimata, 2010, Signaling of extracellular inorganic phosphate up-regulates cyclin D1 expression in proliferating chondrocytes via the Na(+)/Pi cotransporter Pit-1 and Raf/MEK/ERK pathway, Bone, 47, 938, 10.1016/j.bone.2010.08.006
Beck, 2003, Osteopontin regulation by inorganic phosphate is ERK1/2-, protein kinase C-, and proteasome-dependent, J Biol Chem, 278, 41921, 10.1074/jbc.M304470200
Julien, 2007, Phosphate stimulates matrix Gla protein expression in chondrocytes through the extracellular signal regulated kinase signaling pathway, Endocrinology, 148, 530, 10.1210/en.2006-0763
Nair, 1997, Phosphocitrate inhibits a basic calcium phosphate and calcium pyrophosphate dihydrate crystal-induced mitogen-activated protein kinase cascade signal transduction pathway, J Biol Chem, 272, 18920, 10.1074/jbc.272.30.18920
Yamazaki, 2010, Both FGF23 and extracellular phosphate activate Raf/MEK/ERK pathway via FGF receptors in HEK293 cells, J Cell Biochem, 111, 1210, 10.1002/jcb.22842
Bergwitz C, DeRobertis C, Chen H, Friedman A, Jüppner H, Perrimon N. Role of sodium-phosphate co-transporters in the activation of the MAPK pathway by phosphate. J Am Soc Nephrol. In press. Abstract F-FC258.
Mansfield, 2001, Phosphate ions mediate chondrocyte apoptosis through a plasma membrane transporter mechanism, Bone, 28, 1, 10.1016/S8756-3282(00)00409-9
Beck, 2009, Identification of a novel function of PiT1 critical for cell proliferation and independent of its phosphate transport activity, J Biol Chem, 284, 31363, 10.1074/jbc.M109.053132
Suzuki, 2010, Effects of transgenic Pit-1 overexpression on calcium phosphate and bone metabolism, J Bone Miner Metab, 28, 139, 10.1007/s00774-009-0121-3
Beck, 2010, The phosphate transporter PiT1 (Slc20a1) revealed as a new essential gene for mouse liver development, PLoS One, 5, e9148, 10.1371/journal.pone.0009148
Julien, 2009, Phosphate-dependent regulation of MGP in osteoblasts: role of ERK1/2 and Fra-1, J Bone Miner Res, 24, 1856, 10.1359/jbmr.090508
Meng, 2006, Probing early growth response 1 interacting proteins at the active promoter in osteoblast cells using oligoprecipitation and mass spectrometry, J Proteome Res, 5, 1931, 10.1021/pr060009l
Beck, 2003, Inorganic phosphate regulates multiple genes during osteoblast differentiation, including Nrf2, Exp Cell Res, 288, 288, 10.1016/S0014-4827(03)00213-1
Conrads, 2004, Quantitative proteomic analysis of inorganic phosphate-induced murine MC3T3-E1 osteoblast cells, Electrophoresis, 25, 1342, 10.1002/elps.200405892
Sabbagh, 2005, Hypophosphatemia leads to rickets by impairing caspase-mediated apoptosis of hypertrophic chondrocytes, Proc Natl Acad Sci USA, 102, 9637, 10.1073/pnas.0502249102
Miedlich, 2010, Phosphate-induced apoptosis of hypertrophic chondrocytes is associated with a decrease in mitochondrial membrane potential and is dependent upon Erk1/2 phosphorylation, J Biol Chem, 285, 18270, 10.1074/jbc.M109.098616
Oshima, 2008, Pivotal role of Bcl-2 family proteins in the regulation of chondrocyte apoptosis, J Biol Chem, 283, 26499, 10.1074/jbc.M800933200
Magne, 2003, Phosphate is a specific signal for ATDC5 chondrocyte maturation and apoptosis-associated mineralization: possible implication of apoptosis in the regulation of endochondral ossification, J Bone Miner Res, 18, 1430, 10.1359/jbmr.2003.18.8.1430
Donohue, 2002, Rickets in VDR null mice is secondary to decreased apoptosis of hypertrophic chondrocytes, Endocrinology, 143, 3691, 10.1210/en.2002-220454
Jüppner, 2006, Parathyroid hormone and parathyroid hormone-related peptide in the regulation of calcium homeostasis and bone development, 1377
Potts, 1997, Parathyroid Hormone and parathyroid hormone-related peptide in calcium homeostasis, bone metabolism, and bone development: the proteins, their genes, and receptors, 51
White, 2006, The roles of specific genes implicated as circulating factors involved in normal and disordered phosphate homeostasis: frizzled related protein-4, matrix extracellular phosphoglycoprotein, and fibroblast growth factor 23, Endocr Rev, 27, 221, 10.1210/er.2005-0019
Quarles, 2008, Endocrine functions of bone in mineral metabolism regulation, J Clin Invest, 118, 3820, 10.1172/JCI36479
Bergwitz, 2010, Regulation of phosphate homeostasis by PTH, vitamin D, and FGF23, Annu Rev Med, 61, 91, 10.1146/annurev.med.051308.111339
Urakawa, 2006, Klotho converts canonical FGF receptor into a specific receptor for FGF23, Nature, 444, 770, 10.1038/nature05315
Miyamoto, 2007, New aspect of renal phosphate reabsorption: the type IIc sodium-dependent phosphate transporter, Am J Nephrol, 27, 503, 10.1159/000107069
Forster, 2006, Proximal tubular handling of phosphate: a molecular perspective, Kidney Int, 70, 1548, 10.1038/sj.ki.5001813
Berndt, 2007, Evidence for a signaling axis by which intestinal phosphate rapidly modulates renal phosphate reabsorption, Proc Natl Acad Sci USA, 104, 11085, 10.1073/pnas.0704446104
Stubbs, 2007, Role of fibroblast growth factor 23 in phosphate homeostasis and pathogenesis of disordered mineral metabolism in chronic kidney disease, Semin Dial, 20, 302, 10.1111/j.1525-139X.2007.00308.x
Segawa, 2009, Type IIc sodium-dependent phosphate transporter regulates calcium metabolism, J Am Soc Nephrol, 20, 104, 10.1681/ASN.2008020177
Wilz, 1979, Plasma 1,25-(OH)2-vitamin D concentrations and net intestinal calcium, phosphate, and magnesium absorption in humans, Am J Clin Nutr, 32, 2052, 10.1093/ajcn/32.10.2052
Nabeshima, 2009, Discovery of alpha-Klotho unveiled new insights into calcium and phosphate homeostasis, Proc Jpn Acad Ser B Phys Biol Sci, 85, 125, 10.2183/pjab.85.125
Strom, 2008, PHEX, FGF23, DMP1 and beyond, Curr Opin Nephrol Hypertens, 17, 357, 10.1097/MNH.0b013e3282fd6e5b
Kuro-o, 2008, Endocrine FGFs and Klothos: emerging concepts, Trends Endocrinol Metab, 19, 239, 10.1016/j.tem.2008.06.002
Silver, 2005, Regulation of PTH synthesis and secretion relevant to the management of secondary hyperparathyroidism in chronic kidney disease, Kidney Int Suppl, S8, 10.1111/j.1523-1755.2005.09501.x
Gardella, 2009, Mimetic ligands for the PTHR1: approaches developments, and considerations, IBMS BoneKey, 6, 71, 10.1138/20090364
Kronenberg, 2007, PTH regulates the hematopoietic stem cell niche in bone, Adv Exp Med Biol, 602, 57, 10.1007/978-0-387-72009-8_7
Berndt, 2009, Novel mechanisms in the regulation of phosphorus homeostasis, Physiology (Bethesda), 24, 17, 10.1152/physiol.00034.2008
Kemper, 1974, Parathyroid secretion: discovery of a major calcium-dependent protein, Science, 184, 167, 10.1126/science.184.4133.167
Slatopolsky, 1996, Phosphorus restriction prevents parathyroid gland growth. High phosphorus directly stimulates PTH secretion in vitro, J Clin Invest, 97, 2534, 10.1172/JCI118701
Sherwood, 1968, Regulation of parathyroid hormone secretion: proportional control by calcium, lack of effect of phosphate, Endocrinology, 83, 1043, 10.1210/endo-83-5-1043
Almaden, 1996, Direct effect of phosphorus on PTH secretion from whole rat parathyroid glands in vitro, J Bone Miner Res, 970, 10.1002/jbmr.5650110714
Silver, 1985, Regulation by vitamin D metabolites of messenger ribronucleic acid for preproparathyroid hormone in isolated bovine parathyroid cells, Proc Natl Acad Sci USA, 82, 4270, 10.1073/pnas.82.12.4270
Estepa, 1999, Effect of phosphate on parathyroid hormone secretion in vivo, J Bone Miner Res, 14, 1848, 10.1359/jbmr.1999.14.11.1848
Moallem, 1998, RNA-protein binding and post-transcriptional regulation of parathyroid hormone gene expression by calcium and phosphate, J Biol Chem, 273, 5253, 10.1074/jbc.273.9.5253
Naveh-Many, 1995, Parathyroid cell proliferation in normal and chronic renal failure in rats. The effects of calcium, phosphate, and vitamin D, J Clin Invest, 96, 1786, 10.1172/JCI118224
Galitzer, 2008, Fibroblast growth factor 23 acts on the parathyroid to decrease parathyroid hormone secretion, Curr Opin Nephrol Hypertens, 17, 363, 10.1097/MNH.0b013e328303e172
Lavi-Moshayoff, 2009, Human PTH gene regulation in vivo using transgenic mice, Am J Physiol Renal Physiol, 297, F713, 10.1152/ajprenal.00161.2009
Ben-Dov, 2007, The parathyroid is a target organ for FGF23 in rats, J Clin Invest, 117, 4003
Krajisnik, 2007, Fibroblast growth factor-23 regulates parathyroid hormone and 1 alpha-hydroxylase expression in cultured bovine parathyroid cells, J Endocrinol, 195, 125, 10.1677/JOE-07-0267
Imura, 2007, alpha-Klotho as a regulator of calcium homeostasis, Science, 316, 1615, 10.1126/science.1135901
Kilav, 1995, Parathyroid hormone gene expression in hypophosphatemic rats, J Clin Invest, 96, 327, 10.1172/JCI118038
Nechama, 2009, The peptidyl-prolyl isomerase Pin1 determines parathyroid hormone mRNA levels and stability in rat models of secondary hyperparathyroidism, J Clin Invest, 119, 3102, 10.1172/JCI39522
Dinur, 2006, In vitro evidence that upstream of N-ras participates in the regulation of parathyroid hormone messenger ribonucleic acid stability, Mol Endocrinol, 20, 1652, 10.1210/me.2005-0333
Nechama, 2008, The mRNA decay promoting factor K-homology splicing regulator protein post-transcriptionally determines parathyroid hormone mRNA levels, FASEB J, 22, 3458, 10.1096/fj.08-107250
Bikle, 2008
Boullion, 2006, Vitamin D: from photosynthesis, metabolism, and action to clinical application, 1435
Sakaki, 2005, Metabolism of vitamin D3 by cytochromes P450, Front Biosci, 10, 119
Bai, 2003, The autosomal dominant hypophosphatemic rickets R176Q mutation in fibroblast growth factor 23 resists proteolytic cleavage and enhances in vivo biological potency, J Biol Chem, 278, 9843, 10.1074/jbc.M210490200
Carpenter, 2005, Fibroblast growth factor 7: an inhibitor of phosphate transport derived from oncogenic osteomalacia-causing tumors, J Clin Endocrinol Metab, 90, 1012, 10.1210/jc.2004-0357
Berndt, 2003, Secreted frizzled-related protein 4 is a potent tumor-derived phosphaturic agent, J Clin Invest, 112, 785, 10.1172/JCI18563
DeLuca, 1986, The metabolism and functions of vitamin D, Adv Exp Med Biol, 196, 361, 10.1007/978-1-4684-5101-6_24
Inoue, 2005, Role of the vitamin D receptor in FGF23 action on phosphate metabolism, Biochem J, 390, 325, 10.1042/BJ20041799
Yamashita, 2000, Identification of a novel fibroblast growth factor, FGF-23, preferentially expressed in the ventrolateral thalamic nucleus of the brain, Biochem Biophys Res Commun, 277, 494, 10.1006/bbrc.2000.3696
Bastepe, 2008, Inherited hypophosphatemic disorders in children and the evolving mechanisms of phosphate regulation, Rev Endocr Metab Disord, 9, 171, 10.1007/s11154-008-9075-3
von Marschall, 2008, Dentin matrix protein-1 isoforms promote differential cell attachment and migration, J Biol Chem, 283, 32730, 10.1074/jbc.M804283200
Yuan, 2008, 7B2 protein mediated inhibition of DMP1 cleavage in osteoblasts enhances FGF-23 production in hyp-mice, J Bone. Miner Res, 23, S16
Lu, 2009, Studies of the DMP1 57-kDa functional domain both in vivo and in vitro, Cells Tissues Organs, 189, 175, 10.1159/000151727
Lorenz-Depiereux, 2006, DMP1 mutations in autosomal recessive hypophosphatemia implicate a bone matrix protein in the regulation of phosphate homeostasis, Nat Genet, 38, 1248, 10.1038/ng1868
Terkeltaub, 2006, Physiologic and pathologic functions of the NPP nucleotide pyrophosphatase/phosphodiesterase family focusing on NPP1 in calcification, Purinergic Signal, 2, 371, 10.1007/s11302-005-5304-3
Rutsch, 2001, PC-1 nucleoside triphosphate pyrophosphohydrolase deficiency in idiopathic infantile arterial calcification, Am J Pathol, 158, 543, 10.1016/S0002-9440(10)63996-X
Rutsch, 2003, Mutations in ENPP1 are associated with ‘idiopathic’ infantile arterial calcification, Nat Genet, 34, 379, 10.1038/ng1221
Levy-Litan, 2010, Autosomal-recessive hypophosphatemic rickets is associated with an inactivation mutation in the ENPP1 gene, Am J Hum Genet, 86, 273, 10.1016/j.ajhg.2010.01.010
Lorenz-Depiereux, 2010, Loss-of-function ENPP1 mutations cause both generalized arterial calcification of infancy and autosomal-recessive hypophosphatemic rickets, Am J Hum Genet, 86, 267, 10.1016/j.ajhg.2010.01.006
Chodirker, 1990, Hyperphosphatemia in infantile hypophosphatasia: implications for carrier diagnosis and screening, Am J Hum Genet, 46, 280
Burnett, 2006, Regulation of C-terminal and intact FGF-23 by dietary phosphate in men and women, J Bone Miner Res, 21, 1187, 10.1359/jbmr.060507
Nishi, 2005, Intravenous calcitriol therapy increases serum concentrations of fibroblast growth factor-23 in dialysis patients with secondary hyperparathyroidism, Nephron Clin Pract, 101, c94, 10.1159/000086347
Kolek, 2005, 1alpha,25-Dihydroxyvitamin D3 upregulates FGF23 gene expression in bone: the final link in a renal-gastrointestinal-skeletal axis that controls phosphate transport, Am J Physiol Gastrointest Liver Physiol, 289, G1036, 10.1152/ajpgi.00243.2005
Shimada, 2004, FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis, J Bone Miner Res, 19, 429, 10.1359/JBMR.0301264
Yu, 2005, Genetic dissection of phosphate- and vitamin D-mediated regulation of circulating Fgf23 concentrations, Bone, 36, 971, 10.1016/j.bone.2005.03.002
Chefetz, 2009, GALNT3, a gene associated with hyperphosphatemic familial tumoral calcinosis, is transcriptionally regulated by extracellular phosphate and modulates matrix metalloproteinase activity, Biochim Biophys Acta, 1792, 61, 10.1016/j.bbadis.2008.09.016
Bhattacharyya N, Andreopoulou P, Dumitrescu C, Miwa H, Gafni R, Collins M. Cyclic AMP-mediated processing of FGF23: regulation by O-glycosylation. J Bone Miner Res. In press. Abstract A09003028.
Frishberg, 2007, Hyperostosis-hyperphosphatemia syndrome: a congenital disorder of O-glycosylation associated with augmented processing of fibroblast growth factor 23, J Bone Miner Res, 22, 235, 10.1359/jbmr.061105
Bergwitz, 2009, Defective O-glycosylation due to a novel homozygous S129P mutation is associated with lack of fibroblast growth factor 23 secretion and tumoral calcinosis, J Clin Endocrinol Metab, 94, 4267, 10.1210/jc.2009-0961
Larsson, 2005, Fibroblast growth factor-23 mutants causing familial tumoral calcinosis are differentially processed, Endocrinology, 146, 3883, 10.1210/en.2005-0431
Ichikawa, 2009, Ablation of the Galnt3 gene leads to low-circulating intact fibroblast growth factor 23 (Fgf23) concentrations and hyperphosphatemia despite increased Fgf23 expression, Endocrinology, 150, 2543, 10.1210/en.2008-0877