Phenobarbital and propiconazole toxicogenomic profiles in mice show major similarities consistent with the key role that constitutive androstane receptor (CAR) activation plays in their mode of action

Toxicology - Tập 321 - Trang 80-88 - 2014
Richard A. Currie1, Richard C. Peffer2, Amber K. Goetz3, Curtis J. Omiecinski4, Jay I. Goodman5
1Syngenta Ltd, Jealott’s Hill International Research Centre, Bracknell, Berkshire RG42 6EY, UK
2Syngenta Crop Protection, LLC, P.O. Box 18300, Greensboro, NC, 27419-8300, United States
3Syngenta Crop Protection, LLC, P.O. Box 18300, Greensboro, NC 27419-8300, United States
4Center for Molecular Toxicology and Carcinogenesis, Penn State University, University Park, PA 16802, United States
5Department of Pharmacology and Toxicology, Michigan State University, East Lansing, MI 48824, United States

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