Phase II Study of Perioperative Chemotherapy with Cisplatin and Pemetrexed in Non–Small-Cell Lung Cancer

Journal of Thoracic Oncology - Tập 9 - Trang 222-230 - 2014
Grace K. Dy1, Paul N. Bogner1, Wei Tan1, Todd L. Demmy1, Aamer Farooq2, Hongbin Chen1, Saikrishna S. Yendamuri1, Chukwumere E. Nwogu1, Peter W. Bushunow3, James Gannon1, Araba A. Adjei1, Alex A. Adjei1, Nithya Ramnath4
1Roswell Park Cancer Institute, Buffalo, New York
2The Oncology Institute of Hope and Innovation, Anaheim, California
3Rochester General Hospital, Rochester, New York
4Department of Medicine, University of Michigan, Ann Arbor, Michigan

Tài liệu tham khảo

Siegel, 2012, Cancer statistics, 2013, CA Cancer J Clin, 62, 11 Depierre, 2002, Preoperative chemotherapy followed by surgery compared with primary surgery in resectable stage I (except T1N0), II, and IIIa non-small-cell lung cancer, J Clin Oncol, 20, 247, 10.1200/JCO.20.1.247 Rosell, 1999, Preresectional chemotherapy in stage IIIA non-small-cell lung cancer: a 7-year assessment of a randomized controlled trial, Lung Cancer, 26, 7, 10.1016/S0169-5002(99)00045-8 Roth, 1994, A randomized trial comparing perioperative chemotherapy and surgery with surgery alone in resectable stage IIIA non-small-cell lung cancer, J Natl Cancer Inst, 86, 673, 10.1093/jnci/86.9.673 Bromley, 1955, Combined radiotherapy and resection for carcinoma of the bronchus; experiences with 66 patients, Lancet, 269, 937, 10.1016/S0140-6736(55)92787-2 Shields, 1970, Preoperative x-ray therapy as an adjuvant in the treatment of bronchogenic carcinoma, J Thorac Cardiovasc Surg, 59, 49, 10.1016/S0022-5223(19)42513-0 Elias, 1997, Neoadjuvant therapy for surgically staged IIIA N2 non-small cell lung cancer (NSCLC), Lung Cancer, 17, 147, 10.1016/S0169-5002(97)00658-2 Martini, 1993, Preoperative chemotherapy for stage IIIa (N2) lung cancer: the Sloan-Kettering experience with 136 patients, Ann Thorac Surg, 55, 1365, 10.1016/0003-4975(93)91072-U Pisters, 1993, Pathologic complete response in advanced non-small-cell lung cancer following preoperative chemotherapy: implications for the design of future non-small-cell lung cancer combined modality trials, J Clin Oncol, 11, 1757, 10.1200/JCO.1993.11.9.1757 Strauss, 2008, Adjuvant paclitaxel plus carboplatin compared with observation in stage IB non-small-cell lung cancer: CALGB 9633 with the Cancer and Leukemia Group B, Radiation Therapy Oncology Group, and North Central Cancer Treatment Group Study Groups, J Clin Oncol, 26, 5043, 10.1200/JCO.2008.16.4855 Winton, 2005, National Cancer Institute of Canada Clinical Trials Group; National Cancer Institute of the United States Intergroup JBR.10 Trial Investigators. Vinorelbine plus cisplatin vs. observation in resected non-small-cell lung cancer, N Engl J Med, 352, 2589, 10.1056/NEJMoa043623 Arriagada, 2004, International Adjuvant Lung Cancer Trial Collaborative Group. . Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer, N Engl J Med, 350, 351, 10.1056/NEJMoa031644 Douillard, 2006, Adjuvant vinorelbine plus cisplatin versus observation in patients with completely resected stage IB-IIIA non-small-cell lung cancer (Adjuvant Navelbine International Trialist Association [ANITA]): a randomised controlled trial, Lancet Oncol, 7, 719, 10.1016/S1470-2045(06)70804-X Pignon, 2008, Lung adjuvant cisplatin evaluation: a pooled analysis by the LACE Collaborative Group, J Clin Oncol, 26, 3552, 10.1200/JCO.2007.13.9030 Douillard, 2010, Adjuvant chemotherapy for non-small-cell lung cancer: it does not always fade with time, J Clin Oncol, 28, 3, 10.1200/JCO.2009.25.5109 Hu, 2012, Correlation between thymidylate synthase gene polymorphisms and efficacy of pemetrexed in advanced non-small cell lung cancer, Exp Ther Med, 4, 1010, 10.3892/etm.2012.730 Tiseo, 2012, Pharmacogenetic study of patients with advanced non-small cell lung cancer (NSCLC) treated with second-line pemetrexed or pemetrexed-carboplatin, Lung Cancer, 78, 92, 10.1016/j.lungcan.2012.07.009 Smit, 2009, Randomized phase II and pharmacogenetic study of pemetrexed compared with pemetrexed plus carboplatin in pretreated patients with advanced non-small-cell lung cancer, J Clin Oncol, 27, 2038, 10.1200/JCO.2008.19.1650 Adjei, 2010, Correlation between polymorphisms of the reduced folate carrier gene (SLC19A1) and survival after pemetrexed-based therapy in non-small cell lung cancer: a North Central Cancer Treatment Group-based exploratory study, J Thorac Oncol, 5, 1346, 10.1097/JTO.0b013e3181ec18c4 Adjei, 2010, Phase II trial of pemetrexed plus bevacizumab for second-line therapy of patients with advanced non-small-cell lung cancer: NCCTG and SWOG study N0426, J Clin Oncol, 28, 614, 10.1200/JCO.2009.23.6406 Takehara, 2005, Prognostic significance of the polymorphisms in thymidylate synthase and methylenetetrahydrofolate reductase gene in lung cancer, Anticancer Res, 25, 4455 Scagliotti, 2009, The differential efficacy of pemetrexed according to NSCLC histology: a review of two phase III studies, Oncologist, 14, 253, 10.1634/theoncologist.2008-0232 Scagliotti, 2008, Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer, J Clin Oncol, 26, 3543, 10.1200/JCO.2007.15.0375 Martini, 1995, Mediastinal lymph node dissection for lung cancer. The Memorial experience, Chest Surg Clin N Am, 5, 189 http://clinicaltrials.gov. Accessed December 11, 2013. http://clinicaltrials.gov/show/NCT00389688. Accessed December 11, 2013. Scagliotti, 2012, Randomized phase III study of surgery alone or surgery plus preoperative cisplatin and gemcitabine in stages IB to IIIA non-small-cell lung cancer, J Clin Oncol, 30, 172, 10.1200/JCO.2010.33.7089 Felip, 2010, Preoperative chemotherapy plus surgery versus surgery plus adjuvant chemotherapy versus surgery alone in early-stage non-small-cell lung cancer, J Clin Oncol, 28, 3138, 10.1200/JCO.2009.27.6204 Gilligan, 2007, Preoperative chemotherapy in patients with resectable non-small cell lung cancer: results of the MRC LU22/NVALT 2/EORTC 08012 multicentre randomised trial and update of systematic review, Lancet, 369, 1929, 10.1016/S0140-6736(07)60714-4 Pisters, 2010, Surgery with or without preoperative paclitaxel and carboplatin in early-stage non-small-cell lung cancer: Southwest Oncology Group Trial S9900, an intergroup, randomized, phase III trial, J Clin Oncol, 28, 1843, 10.1200/JCO.2009.26.1685 Martin, 2002, Long-term results of combined-modality therapy in resectable non-small-cell lung cancer, J Clin Oncol, 20, 1989, 10.1200/JCO.2002.08.092 Ahmed, 2011, Pathologic response after neoadjuvant carboplatin and weekly paclitaxel for early-stage lung cancer: a Brown University oncology group phase II study, J Thorac Oncol, 6, 1432, 10.1097/JTO.0b013e3182209043 Betticher, 2003, Mediastinal lymph node clearance after docetaxel-cisplatin neoadjuvant chemotherapy is prognostic of survival in patients with stage IIIA pN2 non-small-cell lung cancer: a multicenter phase II trial, J Clin Oncol, 21, 1752, 10.1200/JCO.2003.11.040 Ramnath, 2005, Phase II study of neoadjuvant chemotherapy with gemcitabine and vinorelbine in resectable non-small cell lung cancer, Chest, 128, 3467, 10.1378/chest.128.5.3467 Hou, 2012, Expression profiling-based subtyping identifies novel non-small cell lung cancer subgroups and implicates putative resistance to pemetrexed therapy, J Thorac Oncol, 7, 105, 10.1097/JTO.0b013e3182352a45 Bueno, 2000, Nodal stage after induction therapy for stage IIIA lung cancer determines patient survival, Ann Thorac Surg, 70, 1826, 10.1016/S0003-4975(00)01585-X Higgins, 2011, Persistent N2 disease after neoadjuvant chemotherapy for non-small-cell lung cancer, J Thorac Cardiovasc Surg, 142, 1175, 10.1016/j.jtcvs.2011.07.059 Stefani, 2010, Which patients should be operated on after induction chemotherapy for N2 non-small cell lung cancer? Analysis of a 7-year experience in 175 patients, J Thorac Cardiovasc Surg, 140, 356, 10.1016/j.jtcvs.2010.02.018 Smit, 2012, Biomarker analysis in a phase III study of pemetrexed-carboplatin versus etoposide-carboplatin in chemonaive patients with extensive-stage small-cell lung cancer, Ann Oncol, 23, 1723, 10.1093/annonc/mdr563 Peters, 2009, Association of thymidylate synthase variants with 5-fluorouracil cytotoxicity, Pharmacogenet Genomics, 19, 399, 10.1097/FPC.0b013e328329fdec