Điều chỉnh dược lý của cổng đồng hóa calcium ty thể kiểm soát viêm phổi trong bệnh xơ nang

Science advances - Tập 6 Số 19 - 2020
Alessandro Rimessi1,2, Chiara Pozzato2, Lorenzo Carparelli2, Alice S. Rossi3, Serena Ranucci3, Ida De Fino3, Cristina Cigana3, Anna Maria Talarico4, Mariusz R. Więckowski5, Carla M. P. Ribeiro6, Claudio Trapella4, Giacomo Rossi7, Giulio Cabrini1,8, Alessandra Bragonzi3, Paolo Pinton1,2
1Center of research on Innovative Therapies for Cystic Fibrosis, University of Ferrara, 44121 Ferrara, Italy.
2Department of Medical Sciences and Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, 44121 Ferrara, Italy.
3Infections and Cystic Fibrosis Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, 20132 Milano, Italy.
4Department of Chemistry and Pharmaceutical Sciences and Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, 44121 Ferrara, Italy.
5Laboratory of Mitochondrial Biology and Metabolism, Nencki Institute of Experimental Biology, 02-093 Warsaw, Poland.
6Department of Medicine/Pulmonary Division, Marsico Lung Institute and Cystic Fibrosis Center, Chapel Hill, NC 27599-7248, USA.
7School of Biosciences and Veterinary Medicine, University of Camerino, 62024 Macerata, Italy.
8Department of Neurosurgery, Biomedicine and Movement, University of Verona, 37126 Verona, Italy.

Tóm tắt

Liệu pháp ty thể cung cấp một chiến lược thay thế để giảm thiểu tình trạng viêm quá mức trong bệnh phổi xơ nang.

Từ khóa


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