Pharmacological effects of Catharanthus roseus root alkaloids in acetylcholinesterase inhibition and cholinergic neurotransmission

Phytomedicine - Tập 17 - Trang 646-652 - 2010
David M. Pereira1, Federico Ferreres2, Jorge M.A. Oliveira3, Luís Gaspar1, Joana Faria1, Patrícia Valentão1, Mariana Sottomayor4, Paula B. Andrade1
1REQUIMTE/Department of Pharmacognosy, Faculty of Pharmacy, Porto University, R. Aníbal Cunha, 164, 4050-047 Porto, Portugal
2Research Group on Quality, Safety and Bioactivity of Plant Foods, Department of Food Science and Technology, CEBAS (CSIC), P.O. Box 164, 30100 Campus University Espinardo, Murcia, Spain
3REQUIMTE, Serviço de Farmacologia, Faculdade de Farmácia, Universidade do Porto, R. Aníbal Cunha, 164, 4050-047 Porto, Portugal
4IBMC-Instituto de Biologia Molecular e Celular, Universidade do Porto and Departamento de Botânica, Faculdade de Ciências, Universidade do Porto, R. Campo Alegre 823, 4150-180 Porto, Portugal

Tài liệu tham khảo

Andrade, 2005, Indole alkaloids from Tabernaemontana australis (Müell. Arg) Miers that inhibit acetylcholinesterase enzyme, Bioorg. Med. Chem., 13, 4092, 10.1016/j.bmc.2005.03.045 Bartolucci, 2001, Three-dimensional structure of a complex of galanthamine (Nivalin®) with acetylcholinesterase from Torpedo californica: implications for the design of new anti-Alzheimer drugs, Proteins, 42, 182, 10.1002/1097-0134(20010201)42:2<182::AID-PROT50>3.0.CO;2-1 Blasko, 1990, Isolation, structure elucidation, and biosynthesis of the bisindole alkaloids of Catharanthus, 1 Chopra, 1958 Dong, 1995, Structural studies of vinblastine alkaloids by exciton coupled circular dichroism, Phytochemistry, 40, 1821, 10.1016/0031-9422(95)00627-J Ferreres, F., Pereira, D.M., Valentão, P., Oliveira, J.M.A., Faria, J., Gaspar, L., Sottomayor, M., Andrade, P.B., 2009. Simple and reproducible HPLC-DAD-ESI-MS/MS analysis of alkaloids in Catharanthus roseus roots. J. Pharm. Biomed. Anal. 51, 65–69 Greenblatt, 2004, The complex of a bivalent derivative of galanthamine with Torpedo acetylcholinesterase displays drastic deformation of the active-site gorge: implications for structure-based drug design, J. Am. Chem. Soc., 126, 15405, 10.1021/ja0466154 Hostettmann, 2006, Natural product inhibitors of acetylcholinesterase, Curr. Org. Chem., 10, 825, 10.2174/138527206776894410 Karczmar, 1998, Anticholinesterases: dramatic aspects of their use and misuse, Neurochem. Int., 32, 401, 10.1016/S0197-0186(97)00123-X Kim, 2002, Inhibitory effect of corynoline isolated from the aerial parts of Corydalis incisa on the acetylcholinesterase, Arch. Pharm. Res., 25, 817, 10.1007/BF02976997 Kim, 2004, Acetylcholinesterase inhibitors from the aerial parts of Corydalis speciosa. Arch, Pharm. Res., 27, 1127, 10.1007/BF02975117 Loizzo, 2008, Natural products and their derivatives as cholinesterase inhibitors in the treatment of neurodegenerative disorders: an update, Curr. Med. Chem., 15, 1209, 10.2174/092986708784310422 Lopez, 2002, Acetylcholinesterase inhibitory activity of some Amaryllidaceae alkaloids and Narcissus extracts, Life Sci., 71, 2521, 10.1016/S0024-3205(02)02034-9 Orhan, 2004, Acetylcholinesterase and butyrylcholinesterase inhibitory activity of some Turkish medicinal plants, J. Ethnopharmacol., 91, 57, 10.1016/j.jep.2003.11.016 Orhan, 2009, Contemporary anticholinesterase pharmaceuticals of natural origin and their synthetic analogues for the treatment of Alzheimer's disease, Recent Pat. CNS Drug Discov., 4, 43, 10.2174/157488909787002582 Patrick, 2005 Pelt, 2001 Pereira, 2009, Targeted metabolite analysis of Catharanthus roseus and its biological potential, Food Chem. Toxicol., 47, 1349, 10.1016/j.fct.2009.03.012 Rahman, 2001, Bioactive natural products as a potential source of new pharmacophores. A theory of memory, Pure Appl. Chem., 73, 555, 10.1351/pac200173030555 Rhee, 2001, Screening for acetylcholinesterase inhibitors from Amaryllidaceae using silica gel thin-layer chromatography in combination with bioactivity staining, J. Chromatogr. A, 915, 217, 10.1016/S0021-9673(01)00624-0 Roddick, 1989, The acetylcholinesterase-inhibitory activity of steroidal glycoalkaloids and their aglycones, Phytochemistry, 28, 2631, 10.1016/S0031-9422(00)98055-5 Snape, 1999, A comparative study in rats of the in vitro and in vivo pharmacology of the acetylcholinesterase inhibitors tacrine, donepezil and NXX-066, Neuropharmacology, 38, 181, 10.1016/S0028-3908(98)00164-6 Sottomayor, 2005, The Vinca alkaloids: from biosynthesis and accumulation in plant cells, to uptake, activity and metabolism in animal cells Van der Heijden, 2004, The Catharanthus alkaloids: pharmacognosy and biotechnology, Curr. Med. Chem., 11, 607, 10.2174/0929867043455846