Pharmacological activities of crocin in saffron
Tóm tắt
Từ khóa
Tài liệu tham khảo
Morimoto S, Umezaki Y, Shoyama Y, Saito H, Nishi K, Irino N (1994) Post-harvest degradation of carotenoid glucose esters in saffron. Planta Med 60:438–440
Lijiang X, Tanaka H, Yaming X, Shoyama Y (1999) Preparation of monoclonal antibody against crocin and its characterization. Cytotechnology 29:65–70
Nair SC, Pannikar B, Panikar KR (1991) Antitumour activity of saffron (Crocus sativus. Cancer Lett 57:109–114
Salomi MJ, Nair SC, Panikkar KR (1991) Inhibitory effects of Nigella sativa and saffron (Crocus sativus) on chemical carcinogenesis in mice. Nut Cancer 16:67–72
Konoshima T, Takasaki M, Tokuda H, Morimoto S, Tanaka H, Xuan LJ, Saito H, Sugiura M, Molnar J, Shoyama Y (1998) Crocin and crocetin derivatives inhibit skin tumor promotion in mice. Phytother Res 12:400–404
Miwa T (1954) Study on Gardenia florida L. (Fuructus Gardeniae) as a remedy for icterus. Report IV, on the effect of the active principle and extract of Fuructus Gardeniae on the bile secretion of rabbits, blood bilirubin and peripheral lymph bilirubin of common bile-duct ligated rabbits. Jpn J Pharmacol 4:69–81
Gainer J, Jones JR (1975) The use of crocetin in experimental atherosclerosis. Experimentia 31:548–549
Ishiyama J, Saito H, Abe K (1991) Epidermal growth factor and basic fibroblast growth factor promote the generation of long-term potentiation in the dentate gyrus of anaesthetized rats. Neurosci Lett 12:403–411
Abe K, Xie F, Saito H (1991) Epidermal growth factor enhances short-time potentiation and facilitates induction of long-term potentiation of evoked potential in rat hippocampal slices. Brain Res 547:171–174
Zhang XY, Shoyama Y, Sugiura M, Saito H (1994) Acute effects of Crocus sativus L. on passive avoidance performance in mice. Biol Pharm Bull 17:217–221
Sugiura M, Shoyama Y, Saito H, Abe K (1995) Ethanol extract of Crocus sativus L. antagonizes the inhibitory action of ethanol on hippocampal long-term potentiation in vivo. Phytother Res 9:100–104
Crowe MJ, Bresnahan JC, Shumann SL, Masters JN, Beattie MS (1997) Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys. Nat Med 3:73–76
Hill IE, MacManus JP, Rasquinha I, Tuor UI (1995) DNA fragmentation indicative of apoptosis following unilateral cerebral hypoxia-ischemia in the neonatal rat. Brain Res 676:398–403
Sugiura M, Shoyama Y, Saito H, Abe K (1994) Crocin (crocetin di-gentiobiose ester) prevents the inhibitory effect of ethanol on long-term potentiation in the dentate gyrus in vivo. J Pharmacol Exp Ther 271:703–707
Ochiai T, Soeda S, Ohno S, Tanaka H, Shoyama Y, Shimeno H (2004) Crocin prevents the death of PC-12 cells through sphingomyelinase-ceramide signaling by increasing glutathione synthesis. Neurohem Int 44:321–330
Soeda S, Ochiai T, Paopong L, Tanaka H, Shoyma Y, Shimeno H (2001) Crocin suppresses tumor necrosisi factor-α-induced cell death of neuronally differentiated PC-12 cells. Life Sci 69:2887–2898
Oppenheim R W (1991) Cell death during development of the nervous system. Ann Rev Neurosci 14:453–501
Batistatou A, Green LA (1991) Aurintricarboxylic acid rescues PC-12 cells and sympathetic neurons from cell death caused by nerve growth factor deprivation: correlation with suppression of endonuclease activity. J Cell Biol 115:461–471
Rukenstein A, Rydel RE, Green LA (1991) Multiple agents rescue PC-12 cells from serum-free cell death by translation- and transcription-independent mechanisms. J Neurosci 11:2552–2563
Mesner PW, Winters TR, Green SH (1992) Nerve growth factor withdrawal-induced cell death in neuronal PC-12 cells resembles that in sympathetic neurons. J Cell Biol 119:1669–1680
Pittman RN, Wang S, DiBenedetto AJ, Mills JC (1993) A system for characterizing cellular and molecular events in programmed neuronal cell death. J Neurosci 13:3669–3680
Colombaioni L, Frago LM, Varela-Nieto I, Pesi R, Garcia-Gil M (2002) Serum deprivation increases ceramide levels and induces poptosis in undifferentiated HN9.10e cells. Neurochem Int 40:327–336
Wang E, Norred WP, Bacon CW, Riley RT, Merrill AH Jr (1991) Inhibition of sphingolipid biosynthesis by fumonisins: implications fro diseases associated with Fusarium moniforme. J Biol Chem 266:14486–14490
Merrill AH Jr, van Echten G, Wang E, Sandhoff K (1993) Fumonisin B1 inhibits sphingosine (sphinganine) N-acyltransferase and de novo sphingolipid biosynthesis in ucltured neurons in situ. J Biol Chem 268:27299–27306
Verheij M, Bose R, Lin XH, Yao B, Jarvis WD, Grant S, Birrer MJ, Szabo E, Zon LI, Kyriakis JM, Haimovitz-Friedman A, Fuks Z, Kolesnick RN (1996) Requirement for ceramide-initiated SAPF/JNK signaling in stress-induced apoptosis. Nature 380:75–79
Yoshimura S, Banno Y, Nakashima S, Hayashi K, Yamakawa H, Sawada M, Sakai N, Nozawa Y (1999) Inhibition of neutral sphingomyelinase activation and ceramide formation by glutathione in hypoxic PC-12 cell death. J Neurochem 73:675–683
Yoshimura S, Banno Y, Nakashima S, Takenaka K, Sakai H, Nishimura Y, Sakai N, Shimizu S, Eguchi Y, Tsujimoto Y, Nozawa Y (1998) Ceramide formation leads to caspase-3 activation during hypoxic PC-12 cell death. J Biol Chem 273:6921–6927
Liu B, Hannun YA (1997) Inhibition of the neutral magnesium-dependent sphingomyelinase by glutathione. J Biol Chem 272:16381–16287
Liu B, Andrieu-Abadie N, Levade T, Zhang P, Obeid LM, Hannun YA (1998) Glutathione regulation of neutral shphingomyelinase in tumor necrosis factor-α-induced cell death. J Biol Chem 273:11313–11320
Urata Y, Yamamoto H, Goto S, Tsushima H, Akazawa S, Yamashita S, Nagataki S, Kondo T (1996) Long exposure to high glucose concentration impairs the responsive expression of γ-glutamylcysteine synthase by interleukin-1β and tumor necrosis factor-α in mouse endothelial cells. J Biol Chem 271:15146–15152
Nakajima A, Yamada K, Zou L-B, Yan Y, Mizuno M, Nabeshima T (2002). Interleukin-6 protects PC12 cells from 4-hydroxynonenal-induced cytotoxicity by increasing intracellular glutathione levels. Free Radic Biol Med, 32:1324–1332
Pan Z, Perez-Polo R (1993) Role of nerve growth factor in oxidant homeostasis: glutathione metabolism. J Neurochem 61:1713–1721
Griffith OW, Anderson ME, Meister A (1979) Inhibition of glutathione biosynthesis by prothionine sulfoximine (S-n-propyl homocysteine sulfoximine), a selective inhibitor of γ-glutamylcysteine synthase. J Biol Chem 254:1205–1210
Ochiai T, Ohno S, Soeda S, Tanaka H, Shoyama Y, Shimeno H (2004) Crocin prevents the death of rat pheochromyctoma (PC-12) cells by its antioxidant effects stronger than those of α-tocopherol. Neurosci Lett 362:61–64
Urano S (1993) Membrane stabilization by vitamin E. In: Mino M, Nakamura H, Diplock AT, Kayden HJ (eds) Vitamin E – its usefulness in health and in curing disease. Japan Sci Soc Press, Tokyo, pp 41–50
Niki E (1993) Function of vitamin E as antioxidant in the membranes. In: Mino M, Nakamura H, Diplock AT, Kayden HJ (eds) Vitamin E – its usefulness in health and in curing disease. Japan Sci Soc Press, Tokyo, pp 23–30
Troy CM, Schelanski ML (1994) Down-regulation of copper/zinc superoxide dismutase causes apoptotic death of PC 12 neuronal cells. Proc Natl Acad Sci USA 91:6384–638
Behl C, Moosmann B (2002) Antioxidant neuroprotection in Alzheimer’s disease as preventive and therapeutic approach. Free Radic Biol Med 33:182–191
Harris ME, Hensley K, Butterfield A, Leedle RA, Carney JM (1995) Direct evidence of oxidative injury produced by the Alzheimer’s β-amiloid peptide (1-40) in cultured hippocampal neurons. Exp Neurol 131:193–202
Sano M, Ernesto C, Thomas RG, Klauber MR, Schafer K, Grundman M, Woodbury P, Growdon J, Cotman CW, Pfeiffer E, Schneider LS, Thal LJ (1997) A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer’s disease. N Engl J Med 336:1216–1222
Mishima K, Tanaka T, Pu F, Egashira N, Iwasaki K, Hidaka R, Matsunaga K, Takada J, Karube Y, Fujiwara M (2003) Vitamin E isoforms α-tocotrienol and γ-tocopherol prevent cerebral infarction in mice. Neurosci Lett 337:56–60
Abdullaev FI (2002) Cancer chemopreventive and tumoricidal properties of saffron (Crocus sativus L.). Exp Biol Med 227:20–25
Sugiura M, Shoyama Y, Saito H, Nishiyama N (1995) Crocin improves the ethanol-induced impairment of learning behaviors of mice in passive avoidance tasks. Proc Japan Acad Ser B 71:319–324