Pharmacologic inhibition of ketohexokinase prevents fructose-induced metabolic dysfunction

Molecular Metabolism - Tập 48 - Trang 101196 - 2021
Jemy A. Gutierrez1, Wei Liu1, Sylvie Perez1, Gang Xing1, Gabriele Sonnenberg1, Kou Kou1, Matt Blatnik2, Richard Allen3, Yan Weng4, Nicholas B. Vera1, Kristin Chidsey5, Arthur Bergman4, Veena Somayaji5, Collin Crowley1, Michelle F. Clasquin1, Anu Nigam1, Melissa A. Fulham1, Derek M. Erion1, Trenton T. Ross1, William P. Esler1
1Internal Medicine Research Unit, Pfizer Worldwide Research, Development, and Medical, Cambridge, MA 02139 USA
2Early Clinical Development, Pfizer Worldwide Research, Development, and Medical, Groton, CT 06340 USA
3Quantitative Systems Pharmacology, Pfizer Worldwide Research, Development, and Medical, Cambridge, MA 02139 USA
4Clinical Pharmacology, Pfizer Worldwide Research, Development, and Medical, Cambridge, MA 02139 USA
5Early Clinical Development, Pfizer Worldwide Research, Development, and Medical, Cambridge, MA 02139 USA

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